ライフサイエンスコーパス: histone deacetylase 2

1 (such as PI3K) leading to the inhibition of histone deacetylase 2.

2 rescued by the simultaneous decrease of the Histone Deacetylase 2.

3 se in levels of the memory repressor protein histone deacetylase 2.

4 icosteroid resistance though inactivation of histone deacetylase 2.

5 uding BRG1, BRM, hSNF2H, BAF155, mSin3a, and histone deacetylase 2.

6 dent repression domain, which interacts with histone deacetylase 2.

7 of brain sections showed that TopIIbeta and histone deacetylase 2, a known TopIIbeta-interacting pro

8 ed inflammatory genes through recruitment of histone deacetylase-2, activating anti-inflammatory gene

9 effect may be due to inhibition of PDE4 and histone deacetylase-2 activation, resulting in switching

10 of 1) chromatin perturbation by mutation of histone deacetylases, 2) activation of Snf1, and 3) the

11 lar value in severe asthma and COPD, wherein histone deacetylase-2 activity is reduced.

12 ardiac function via p27/casein kinase-2alpha/histone deacetylase 2 and indicate that mutations within

13 e demonstrate that Hu proteins interact with histone deacetylase 2 and inhibit its deacetylation acti

14 nflammation enhanced the interaction between histone deacetylase 2 and methyl-CpG-binding protein 2,

15 1 and methylated CpG binding protein 2 with histone deacetylase 2 and of REST with histone deacetyla

16 r the development of selective inhibitors of histone deacetylase 2 and suggest that cognitive capacit

17 eacetylase 1 but had no effect on binding to histone deacetylases 2 and 3, the coactivator p300, or e

18 and increased methyl-CpG binding protein-2, histone-deacetylase-2, and switch-independent-3a binding

19 Histone deacetylase 2 associates with and reduces the hi

20 rodegeneration, and a human homolog of RPD3, histone deacetylase 2, bound ATM and abrogated ATM activ

21 Importantly, reversing the build-up of histone deacetylase 2 by short-hairpin-RNA-mediated knoc

22 anscription, and FosB in turn, utilizes FosB/histone deacetylase 2 complex to repress E-cadherin expr

23 de novo methylation of the promoter, whereas histone deacetylase 2 cooperates with DNMT1 to inhibit t

24 sor 1, methylated CpG binding protein 2, and histone deacetylase 2 enrichment, but not of sirtuin 1 o

25 through epigenetic modifications mediated by histone deacetylase 2 (HDAC-2).

26 recruitment of the transcriptional repressor histone deacetylase-2 (HDAC-2) to this site.

27 A reduction in histone deacetylase 2 (HDAC2) activity and expression ha

28 ubiquitin ligase activity, by recruiting the histone deacetylase 2 (HDAC2) and CCAAT/enhancer-binding

29 ng molecule that mediates S-nitrosylation of histone deacetylase 2 (HDAC2) and epigenetic changes in

30 FOXP3 specifically inhibited binding of histone deacetylase 2 (HDAC2) and HDAC4 to the site and

31 LPS stimulates S-nitrosylation of histone deacetylase 2 (HDAC2) and interferes with its bi

32 e nucleus, accompanied by S-nitrosylation of histone deacetylase 2 (HDAC2) and Sirtuin 1 (SIRT1), dea

33 RFX5 specifically interacts with histone deacetylase 2 (HDAC2) and the mammalian transcri

34 expression by recruiting chromatin modifier histone deacetylase 2 (HDAC2) as revealed by chromatin i

35 lying mechanism involves recruitment of MTA1-histone deacetylase 2 (HDAC2) complexes onto two selecti

36 previously shown that subunits of the mSin3A/histone deacetylase 2 (HDAC2) corepressor complex copuri

37 onstrate that the chromatin-modifying enzyme histone deacetylase 2 (Hdac2) functions with a small hom

38 triggers NO synthesis and S-nitrosylation of histone deacetylase 2 (HDAC2) in neurons, resulting in c

39 ilencing of histone deacetylase 1 (Hdac1) or histone deacetylase 2 (Hdac2) in OPCs did not affect BMP

40 ation is associated with decreased levels of histone deacetylase 2 (HDAC2) in the nucleus accumbens.

41 Histone deacetylase 2 (HDAC2) is a member of a large fam

42 Histone deacetylase 2 (HDAC2) negatively regulates excit

43 ng to the glucocorticoid response element of histone deacetylase 2 (HDAC2) promoter, resulting in the

44 ted by acetylation of core histones, whereas histone deacetylase 2 (HDAC2) suppresses inflammatory ge

45 Corticosteroids recruit histone deacetylase 2 (HDAC2) to the actively transcribi

46 es FOXM1 bound to the FHRE before recruiting histone deacetylase 2 (HDAC2) to the promoter, leading t

47 Association of histone deacetylase 2 (Hdac2) with T-Cad promoter and re

48 d the glucocorticoid receptor (GR-alpha) and histone deacetylase 2 (HDAC2), a corepressor important f

49 s of inhibitor kappaB-alpha (IkappaB-alpha), histone deacetylase 2 (HDAC2), acetylated (ac-) histone

50 ted to its N-terminal domain, which recruits histone deacetylase 2 (Hdac2), as demonstrated by (i) im

51 istance is largely caused by inactivation of histone deacetylase 2 (HDAC2), which is critical for the

52 munoprecipitation assay experiments revealed histone deacetylase 2 (HDAC2)-MTA1 protein-protein inter

53 eacetylase (HDAC) inhibitors or knockdown of histone deacetylase 2 (HDAC2).

54 ach virus results in hyperphosphorylation of histone deacetylase 2 (HDAC2).

55 cription factor activator protein 1, reduced histone deacetylase-2 (HDAC2) expression, raised macroph

56 ve inflammation via reduced transcription of histone deacetylase-2 (HDAC2) in lung epithelial and mac

57 Histone deacetylase-2 (HDAC2) is a component of a comple

58 Here we show that histone deacetylase-2 (Hdac2) regulates expression of ma

59 oter by binding to nearby DNA and recruiting histone deacetylase-2 (HDAC2) to reduce histone acetylat

60 Histone deacetylase-2 (HDAC2), an epigenetic regulator,

61 4 (also called Mi-2beta) is a component of a histone-deacetylase-2 (HDAC2)-containing complex, the nu

62 (CoREST), histone deacetylase 1 (HDAC1), and histone deacetylase 2 in erythroleukemia and T cell leuk

63 e repressor CoREST (also known as RCOR1) and histone deacetylase 2 in these early dividing cells; and

64 at the essential nuclear gene, P. falciparum histone deacetylase 2 (PfHda2), is a global silencer of

65 ownstream molecules casein kinase-2alpha and histone deacetylase 2 were significantly elevated in Eya

66 This blockade is mediated by histone deacetylase 2, which is increased by Alzheimer's