ライフサイエンスコーパス: histone modifying enzyme

1 uitment of nucleosome remodeling factors and histone modifying enzymes.

2 icate balance between opposing activities of histone modifying enzymes.

3 of nucleosome disruption in the presence of histone modifying enzymes.

4 -dependent nucleosome remodeling enzymes and histone modifying enzymes.

5 e elements, co-activators/co-repressors, and histone modifying enzymes.

6 ses transcription without the requirement of histone-modifying enzymes.

7 hibits BA synthesis by recruiting repressive histone-modifying enzymes.

8 elements through RNAi-mediated targeting of histone-modifying enzymes.

9 eged state, which is partially controlled by histone-modifying enzymes.

10 essive effect of energy restriction on these histone-modifying enzymes.

11 onal regulation by partnering with different histone-modifying enzymes.

12 tion of individual histone modifications and histone-modifying enzymes.

13 otes association of chromatin-remodeling and histone-modifying enzymes.

14 Manipulation of histone modifying enzymes and the signaling pathways tha

15 The activity of histone-modifying enzymes and histone modifications of d

16 s those encoding ribosomal proteins, DNA and histone-modifying enzymes and proteins involved in post-

17 ion factors, chromatin remodeling complexes, histone-modifying enzymes and subset-specific transcript

18 ess has been made in the characterization of histone-modifying enzymes and the roles they play in tra

19 understanding of physiological functions of histone-modifying enzymes and their molecular mechanisms

20 ordinated activity of transcription factors, histone modifying enzymes, and ATP-dependent chromatin r

21 -specific DNA-binding transcription factors, histone-modifying enzymes, and chromatin-remodeling enzy

22 splicing regulation via local recruitment of histone-modifying enzymes, and emerging evidence points

23 are present in the promoters of the affected histone-modifying enzymes, and luciferase reporter assay

24 , including other AP2 transcription factors, histone-modifying enzymes, and regulators of nucleosome

25 o interact with other transcription factors, histone-modifying enzymes, and transcription elongation

26 Histone-modifying enzymes are responsible for regulating

27 he results support pharmaceutical control of histone modifying enzymes as a strategy for controlling

28 Gene silencing at these loci requires histone-modifying enzymes as well as factors that regula

29 ctivity-dependent regulation is unique among histone-modifying enzymes but consistent with redox sens

30 verse set of chromatin regulators, including histone-modifying enzymes, chromatin remodelers, and his

31 d previously unappreciated interplay between histone-modifying enzymes, citrullination of nonhistone

32 "active" and "repressive" cross-talk between histone-modifying enzymes coexist on the same multigene

33 ize DNA in a sequence-specific manner, and a histone modifying enzyme complex are responsible for ind

34 Histone modifying enzymes contribute to the activation o

35 nct patterns of modifications established by histone-modifying enzymes control diverse chromosomal pr

36 of 16 long intergenic noncoding RNAs and key histone modifying enzymes critical for circadian gene ex

37 e demethylases are the most recent family of histone-modifying enzymes discovered.

38 out ESCs and the inhibitors of Lsd1 and p300 histone modifying enzymes during differentiation of E14T

39 many IL-6-dependent genes, catalyzed by the histone-modifying enzyme enhancer of zeste homolog 2 (EZ

40 DNA methylation then leads to recruitment of histone-modifying enzymes, followed by establishment of

41 anti-senescence role in primary cells, this histone-modifying enzyme functions more broadly in the r

42 The histone-modifying enzyme G9a/KMT1C can act both as a coa

43 onse, but not earlier, Blimp-1 recruited the histone-modifying enzymes G9a and HDAC2 to the Il2ra and

44 Dysregulation of histone modifying enzymes has been associated with numer

45 Many histone-modifying enzymes have additional nonhistone sub

46 Accordingly, several histone-modifying enzymes have been described as proto-o

47 Histone-modifying enzymes have enormous potential as reg

48 ne residues remains a challenge because many histone-modifying enzymes have nonhistone targets.

49 of histone deacetylases (HDACs), a class of histone-modifying enzymes, have promising effects in can

50 The functions of histone-modifying enzymes Hdac1(rpd3) and Su(var)3-9 and

51 We found that two histone-modifying enzymes, HDAC1 and HDAC2, were require

52 we showed that during mouse development, the histone-modifying enzyme histone deacetylase 3 (Hdac3) r

53 Recent studies have shown that the histone-modifying enzymes histone acetyltransferase (HAT

54 Histone-modifying enzymes, histone deacetylases (HDACs),

55 lymphoma (DLBCL) tumors contain mutations in histone-modifying enzymes (HMEs), indicating a potential

56 combinations of reader and writer domains in histone-modifying enzymes implement local rewriting rule

57 Recurrent mutations in histone-modifying enzymes imply key roles in tumorigenes

58 With a limited number of histone-modifying enzymes, implying less redundancy, Try

59 USF1 is present in complexes with histone modifying enzymes in cell extracts, and these en

60 These results implicate MET-2 as a second histone-modifying enzyme in germ-line reprogramming and

61 This study identifies LSD1 as a novel histone-modifying enzyme in the orchestrated regulation

62 romatin remodeler, transcription factor, and histone-modifying enzyme in the regulation of the plurip

63 cent advances have shown the crucial role of histone-modifying enzymes in controlling gene activation

64 ever, the cellular and molecular etiology of histone-modifying enzymes in craniofacial disorders is u

65 However, the role of histone-modifying enzymes in the adult brain is still fa

66 Although an essential role for histone-modifying enzymes in these processes is well est

67 ndent chromatin remodeling factors, and some histone-modifying enzymes including Elongator were repea

68 reversibly on lysine or arginine residues by histone-modifying enzymes, including lysine and arginine

69 We therefore conclude that a histone modifying enzyme is necessary to permit an ATP-d

70 In worms, a histone-modifying enzyme is necessary to keep small RNA-

71 t of transcriptional coactivators, including histone modifying enzymes, is an important step in trans

72 t polycomb group (PcG) proteins, a subset of histone-modifying enzymes known to be crucial for B-cell

73 However, regulatory mechanisms for histone modifying enzymes like Set2 that travel with elo

74 e-dependent chromatin-remodeling enzymes and histone-modifying enzymes may regulate transcription by

75 rk for understanding how a broadly expressed histone-modifying enzyme mediates cell-type-specific GAT

76 In addition, histone-modifying enzymes often have multiple nonhistone

77 e of effects on CNS2-mediated recruitment of histone-modifying enzymes p300 and JmjC domain-containin

78 Histone-modifying enzymes play a critical role in modula

79 As Pol II associates with histone-modifying enzymes, Pol II tracking might be crit

80 Histone-modifying enzymes regulate transcription and are

81 sion via morpholino technologies of a single histone-modifying enzyme, Rps6ka4/Msk2, resulted in clea

82 pe is the result of the abnormal activity of histone-modifying enzymes, specifically, class I histone

83 in remodeling factors occurs in concert with histone modifying enzymes such as histone acetyltransfer

84 harmacological modulation of the activity of histone-modifying enzymes, such as histone deacetylases,

85 d structure of heterochromatin by recruiting histone-modifying enzymes, such HDAC1/2, SETDB1, and nuc

86 eading strand DNA polymerase, and associated histone modifying enzymes that spread heterochromatin wi

87 We identify a histone-modifying enzyme that selectively methylates the

88 ing platform for various mRNA processing and histone-modifying enzymes that act co-transcriptionally.

89 Therefore, we tested whether RD2 contacts histone-modifying enzymes that may mediate both repressi

90 ugh recruitment of transcription factors and histone-modifying enzymes that shape muscle differentiat

91 oteins (MBPs) followed by the recruitment of histone-modifying enzymes that together promote chromati

92 ding surfaces, preventing the recruitment of histone modifying enzymes, thereby specifying a new patt

93 from the repressive effect of CG-12 on these histone-modifying enzymes, thereby abolishing the activa

94 hemical reagents for capturing site-specific histone-modifying enzymes, thus providing molecular insi

95 ins, which involves the physical coupling of histone modifying enzymes to histone binding proteins.

96 L) complex composed of noncoding roX RNA and histone modifying enzymes to hypertranscribe most genes

97 es a SP1- and SMAD3-dependent recruitment of histone modifying enzymes to the PLOD2 promoter other th

98 H1 also helps to tether DNA- and histone-modifying enzymes to chromatin.

99 Most coregulator complexes contain histone-modifying enzymes to control ERalpha target gene

100 lomeres in Saccharomyces cerevisiae requires histone-modifying enzymes to create chromatin domains th

101 on protein 16 of transcriptional factors and histone-modifying enzymes to immediate early (alpha) gen

102 These TALE factors recruit histone-modifying enzymes to promote an active chromatin

103 as transcriptional repressors by recruiting histone-modifying enzymes to promoters and enhancers of

104 ecruiting chromatin-remodeling complexes and histone-modifying enzymes to the HIV-1 long terminal rep

105 Etv5 recruits histone-modifying enzymes to the Il17a-Il17f locus, resu

106 Furthermore, Ssdp1/2 recruit histone-modifying enzymes to the motor neuron-specifying

107 expression in VSMCs by identification of the histone-modifying enzymes, transcription factors, and co

108 during the epigenetic reprogramming process, histone-modifying enzymes work together with Smad1 to fa