ライフサイエンスコーパス: hnRNP-F

1 hnRNP F had a higher frequency of expression than CKB in

2 hnRNP F may be a potential target in the treatment of hy

3 hnRNP F stimulated Sirtuin-1 transcription via hnRNP F-r

4 Interestingly, AS targets of the QKI-6-hnRNP F/H pathway in OLs are differentially affected in

5 The sumoylation of hnRNP A1, hnRNP F, and hnRNP K were confirmed in vivo by coimmunop

6 ophy, and glomerulotubular fibrosis in Akita hnRNP F-Tg mice.

7 TB, Fox, Muscleblind, CELF/CUG-BP, TIA-1 and hnRNP F/H, respectively.

8 CKB and hnRNP F were expressed in 78% and 89% of colon tumors, r

9 These results establish hnRNP H and hnRNP F as being repressors of exon inclusion and sugges

10 We show that hnRNP H and hnRNP F proteins are present in a complex with Fox2 and

11 In this study, we identify hnRNP H and hnRNP F proteins as being novel silencers of fibroblast

12 ess is known, however, about how hnRNP H and hnRNP F silence exons.

13 ence was used to knock down both hnRNP H and hnRNP F.

14 at least seven SR proteins and repressed by hnRNPs F, H and I, supporting an extensive antagonism of

15 d with control plasmid or plasmid containing hnRNP F cDNA in vitro.

16 Our results define hnRNP F as a regulatory element of MBP expression in oli

17 reviously shown that Glorund, the Drosophila hnRNP F/H homolog, contributes to anterior-posterior axi

18 , heterogeneous nuclear ribonucleoprotein F (hnRNP F) and high mobility group box 1 protein (HMGB1) i

19 fection of heterogenous ribonucleoprotein F (hnRNP F) or small interfering RNA resulted in lower abun

20 f heterogeneous nuclear ribonucleoprotein F (hnRNP F) overexpression on angiotensinogen (Agt) gene ex

21 f heterogeneous nuclear ribonucleoprotein F (hnRNP F) renoprotective action in a type 2 diabetes (T2D

22 ified a broad spectrum of in vivo functional hnRNP F/H targets in OLs that contain conserved exons fl

23 lement were identified as hnRNP A1, hnRNP H, hnRNP F, and SF2/ASF by site-specific cross-linking and

24 port of additional hnRNP proteins, including hnRNP F.

25 binding motifs related to those in mammalian hnRNP F and H, which play roles in regulated RNA splicin

26 These results demonstrate that mammalian hnRNP F can act as a negative regulator in the pre-mRNA

27 DCS has been shown to assemble hnRNP H, not hnRNP F, from HeLa cell extracts, and we show that hnRNP

28 more RPTC apoptosis and lower expression of hnRNP F, SIRTUIN-1, and FOXO3alpha than nondiabetic kidn

29 ndrocytes and imply an important function of hnRNP F in the control of myelin synthesis.

30 These results suggest an involvement of hnRNP F and CKB in colorectal cancer.

31 we demonstrate that a change in the level of hnRNP F is an important determinant in the regulated use

32 s studied both showed high protein levels of hnRNP F in colon tumors compared with normal colon tissu

33 inase activity results in phosphorylation of hnRNP F in the cytoplasm and its release from MBP mRNA a

34 analyses of cellular proteins, the ratio of hnRNP F to H or H' was found to be higher in memory B ce

35 ence that cytoplasmic QKI-6 acts upstream of hnRNP F/H, which forms a novel pathway to control AS in

36 hat the overexpression of either hnRNP H1 or hnRNP F resulted in the dramatic silencing of exon IIIc.

37 sgenic (Tg) mice specifically overexpressing hnRNP F in their RPTCs were created, and the effects on

38 sgenic (Tg) mice specifically overexpressing hnRNP F in their RPTCs.

39 of Sirtuin-1 small interfering RNA prevented hnRNP F stimulation of Foxo3alpha and downregulation of

40 Here, we identify the RNA-binding protein hnRNP F as a novel component of MBP mRNA transport granu

41 nRNP H can interact with the related protein hnRNP F, suggesting that hnRNPs H and F may exist as a h

42 ts of this enhancer complex are the proteins hnRNP F, KSRP, and an unidentified protein of 58 kDa (p5

43 Fourth, overexpression of recombinant hnRNP F in plasma cells resulted in a decrease in the en

44 B), heterogeneous nuclear ribonucleoprotein (hnRNP) F/H and E/K are identified as interacting SRE pai

45 rs, heterologous nuclear ribonucleoproteins (hnRNPs) F and H.

46 Our results demonstrate that hnRNP F protects kidneys against oxidative stress and ne

47 , using a recombinant protein we showed that hnRNP F could bind to the region downstream of a poly(A)

48 The results showed that hnRNP F overexpression attenuated systemic hypertension,

49 Additionally, they suggest that hnRNP F is a potential marker for colorectal cancer prog

50 These data suggest that hnRNP F plays a modulatory role and can ameliorate hyper

51 RNP F stimulated Sirtuin-1 transcription via hnRNP F-responsive element in the Sirtuin-1 promoter.

52 In vitro, hnRNP F overexpression prevented the high-glucose stimul

53 In vitro, hnRNP F overexpression stimulated Sirtuin-1 and Foxo3alp