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1 reatments are unsatisfactory but surgery may hold promise.
2 ions and payment reform for injectable drugs hold promise.
3   Potent, broad-spectrum protection by nmAbs holds promise.
4 l for ACAA detection and discovery, and they hold promise as a diagnostic for the evaluation and moni
5 t-potentiated task performance may therefore hold promise as a non-subjective measure of individual a
6 ors (5-hydroxytryptamine receptor 4 [5HT4R]) hold promise as a novel therapeutic approach to multiple
7 eted, community-based HIV testing strategies hold promise as a scalable and effective means to identi
8  fast-growing adventitious root cultures may hold promise as a sustainable resource for the large-sca
9 rchestration of sensory neurogenesis and may hold promise as a target for new pain therapeutics.
10 nhibition of alphavbeta1 integrin could thus hold promise as a therapeutic intervention in CKD charac
11 est that differentiation-targeted treatments hold promise as a therapeutic strategy in GI cancer.
12 nt of PSGL-1, and they suggest that CD43 may hold promise as a therapeutic target to modulate Th17 ce
13 ion of macrophages, including NF-kappaB, may hold promise as an adjunct therapeutic avenue for pneumo
14 findings suggest that SERCA2b activation may hold promise as an effective therapy for type-2 diabetes
15 nvironment warrant further investigation and hold promise as an immunotherapeutic strategy.
16 atively affect both host and microbiota, may hold promise as an inflammatory bowel disease therapy.
17        Molecules involved in this system may hold promise as early therapeutic targets for late-life
18 hibitors under development that, as a group, hold promise as effective cancer treatments.
19  and phosphonate ligand-functionalized MMSNs hold promise as effective sorbents for sequestering U fr
20 ke coaching in healthy dietary practices may hold promise as effective, practical, nonstigmatizing in
21                                  Solar cells hold promise as energy conversion devices due to their u
22 ural systems, principles of its organization hold promise as general prototypes of rhythms in other f
23 ng PNAs are unique and potent compounds that hold promise as inhibitors of cellular functions that ar
24 l-asparaginases, our engineered ErA variants hold promise as l-asparaginases with fewer side effects.
25 lized through a helical conjugated backbone, hold promise as models for investigating phenomena arisi
26 amidate N-H), which suggests that they might hold promise as new hydrogen-bonding hosts for optoelect
27                             These nanobodies hold promise as new tools for research, diagnosis and th
28  in pain, therapeutics targeting this system hold promise as novel analgesics.
29            Altogether, BRCA1 and CRISP2 DMRs hold promise as novel blood surrogate markers for early
30      Lanthanide doped nanoparticles (Ln:NPs) hold promise as novel luminescent probes for numerous ap
31     Thus, targeted osteocyte therapies could hold promise as novel osteoporosis and disuse-induced bo
32                  These bispecific antibodies hold promise as novel prophylactic and/or therapeutic ag
33 sis at multiple levels, and these approaches hold promise as novel therapies.
34 ology and signaling suggest new targets that hold promise as potential molecular therapeutics includi
35           Microtubule (MT) stabilizing drugs hold promise as potential treatments for Alzheimer's dis
36            Urban greening and tree cover may hold promise as proactive strategies to decrease urban v
37                           Regulatory T cells hold promise as targets for therapeutic intervention in
38 ms of ischaemia-reperfusion injury, and some hold promise as targets of therapeutic relevance.
39 NFR2 and introduce novel TNFR2 agonists that hold promise as therapeutics to treat a variety of disea
40 lNAc-T) family are currently unavailable but hold promise as therapeutics, especially if selective ag
41 s suggest that iPSC-based population studies hold promise as tools for the functional validation of G
42             Consequently, FKBP5 blockade may hold promise as treatment intervention for stress-relate
43 throughput screening for inhibitors that may hold promise as treatments for retroviral infections and
44 lic awareness, mobilisation, and empowerment hold promise as universal methods to reset all other con
45 t activators of the innate immune system and hold promise as vaccine adjuvant and for anticancer immu
46  light-activated gene regulation, while also holding promise as light-activated agents for spatiotemp
47 and circulation in peripheral blood, thereby holding promise as not only a TME-derived anticancer tar
48  penetrant mutations or sporadic forms - and holds promise as a biomarker for diagnosis and novel dru
49                                    XJB-5-131 holds promise as a clinical candidate for the treatment
50           Thus, PET imaging of NFTs not only holds promise as a diagnostic tool but also may enable t
51               This living bacteria interface holds promise as a dynamic substrate for stem cell diffe
52                               Nitryl cyanide holds promise as a high energy density material (HEDM) a
53 etalloproteinase inhibitors, such as TIMP-4, holds promise as a means to interrupt the progression of
54                                  PET imaging holds promise as a method to study, at the molecular lev
55                                      It also holds promise as a new fluorophore, since initial screen
56                            (99m)Tc-duramycin holds promise as a noninvasive imaging radiotracer for e
57 ating that use of low-affinity anti-IgE mAbs holds promise as a novel therapeutic approach for IgE-me
58 suggesting that hepcidin-ferroportin pathway holds promise as a novel therapeutic target in the treat
59 f glutaminase by nanoparticle drug delivery, holds promise as a novel therapy for pancreatic cancer.
60 the combination of voruciclib and venetoclax holds promise as a novel, exclusively oral combination t
61 to behaving like an animal hormone, ABA also holds promise as a nutraceutical plant-derived compound
62                      Whole-body hyperthermia holds promise as a safe, rapid-acting, antidepressant mo
63                      Network kernel analysis holds promise as a sensitive method for detecting biolog
64 enzyme's Km or Vmax are medicinally targeted-holds promise as a strategy in the design of therapies f
65         Our data suggest that [F-18]-AV-1451 holds promise as a surrogate marker for the detection of
66 satile microfluidics, cellular interrogation holds promise as a systematic strategy that can compleme
67 g activin and its related signaling pathways holds promise as a therapeutic approach to these disease
68                                        Titin holds promise as a therapeutic target for heart failure
69                                   The method holds promise as a tool to discover other novel organize
70 -specific gene editing in many organisms and holds promise as a tool to generate models of human dise
71 Nevertheless, exploiting this unique biology holds promise as a viable strategy for the development o
72       Therefore, this class of CB1R agonists holds promise as a viable treatment for neuropathic pain
73                             This development holds promise as an alternative to single-plex RT-qPCR m
74 acterially produced unglycosylated G protein holds promise as an economical approach to a protective
75 ibition of Wnt signaling by PORCN inhibition holds promise as differentiation therapy in genetically
76                              Cibinetide thus holds promise as novel disease-modifying therapeutic of
77 r dementia, indicative that these antibodies hold promising diagnostic potential.
78 Our results show that this design philosophy holds promise, enables microwave-free control, and offer
79                       Stem cell therapy once held promise for generating large quantities of neurons
80                 Treatments targeting ALT may hold promise for a broadly applicable therapeutic modali
81                                These results hold promise for a new generation of bistable, ultrahigh
82 organic) multication lead halide perovskites hold promise for a new generation of easily processable
83                                   The latter hold promise for a variety of applications, such as ener
84  of circulating, tumor-derived nucleic acids hold promise for addressing the challenge of developing
85          Thus, neutralization of PTHrP might hold promise for ameliorating cancer cachexia and improv
86 ng the Bcl-2/Bcl-xL-Beclin 1 interaction may hold promise for ameliorating hypercapnia-induced immuno
87                                   Nanolasers hold promise for applications including integrated photo
88                                         CTCs hold promise for cancer diagnosis and prognosis and to i
89 sical activity components suggests that they hold promise for childhood obesity prevention worldwide.
90   With recent clinical approval, epothilones hold promise for clinical use after CNS injury.
91 cal halophytes whose edible succulent shoots hold promise for commercial production in saline water.
92                                 These models hold promise for complex neurological diseases such as A
93 s study indicates that peroxymonosulfate may hold promise for decontamination of prion-contaminated s
94 ion studies to rare variants, these findings hold promise for defining the pathogenesis of brain diso
95 rative and cell cycle-related functions, and hold promise for development of novel therapeutic approa
96 operties in all-inorganic halide perovskites hold promise for diverse applications such as phononic a
97 ets of sequence-homogenized domains that may hold promise for engineering efforts since they exhibit
98 s cobalamin-catalysed organic reactions that hold promise for environmentally friendly cobalt catalys
99 ore, orthologous esk1 kak double mutants may hold promise for ethanol production in crop plants.
100 atorial approaches targeting the Raf pathway hold promise for even more substantial clinical benefits
101 ain, demonstrated in anaesthetized rats, and hold promise for future in vivo studies in animal models
102 for efficient treatment remain, these trials hold promise for future phase III clinical trials.
103                              Novel therapies hold promise for high-risk smoldering multiple myeloma (
104 in patients with a high-risk profile and may hold promise for identification of vulnerable plaque.
105                                  Our methods hold promise for identifying and addressing sources of b
106 physical techniques, and screening libraries hold promise for identifying suitable agents that could
107 advances in experimental closed-loop systems hold promise for improved clinical benefit in patients w
108         Bimetallic, nanostructured materials hold promise for improving catalyst activity and selecti
109 e final Phase 3 of the 1000 Genomes Project, hold promise for improving imputation accuracy in geneti
110 highlighting processes warranting study that hold promise for improving mechanistic understanding of
111                    Adaptive decoding methods hold promise for improving neuroprosthetic performance i
112 uality two-dimensional chalcogenide crystals hold promise for innovations of next-generation photodet
113                         This methodology may hold promise for large cetaceans in the wild for which r
114 ompacted mucus penetrating DNA nanoparticles hold promise for lung gene therapy.
115 he mammalian target of rapamycin pathway may hold promise for malformation-associated epilepsy.
116 second harmonic of an Nd:YAG laser (532 nm), hold promise for manipulating and interrogating biologic
117             Integrating DNA delivery systems hold promise for many applications including treatment o
118                       Personalized medicines hold promise for many diseases.
119                                    They thus hold promise for metastasis diagnosis, image-guided surg
120  These data suggest that the MYOM3 fragments hold promise for minimally invasive assessment of experi
121 l protein functions in a reversible fashion, hold promise for modulating intracellular signaling netw
122       Biosensors with direct electron output hold promise for nearly seamless integration with portab
123 otic resistance, natural products once again hold promise for new antimicrobial therapies, especially
124                           These insights may hold promise for new treatments for addiction.
125 lecular basis of age-related memory loss may hold promise for new treatments for cognitive disorders.
126                                    Skyrmions hold promise for next-generation magnetic storage as the
127 etasurfaces are planar optical elements that hold promise for overcoming the limitations of refractiv
128                                  The results hold promise for polysaccharide solubilization under mil
129                 Microscopic swimming devices hold promise for radically new applications in lab-on-a-
130 hese results, involving a simple PHE device, hold promise for realizing programmable logic elements i
131                           Artificial muscles hold promise for safe and powerful actuation for myriad
132 ular, crystalline, and porous materials that hold promise for storage and transport of chemical cargo
133  In vitro methods for interneuron generation hold promise for studying human cellular and functional
134                                Although CPMs hold promise for supporting sex-specific decision making
135 selective electrocatalysts for CO2 reduction hold promise for sustainable fuel production.
136 ogy, multi-target pharmacological strategies hold promise for tackling disease-related networks.
137 al and ADME profile of this corrector series hold promise for the development of more efficacious com
138 hich target specific cytokines and pathways, hold promise for the future.
139 by which HPV induces genomic instability and hold promise for the identification of drug targets.
140 chemical cells (DS-PECs) for water splitting hold promise for the large-scale storage of solar energy
141                                 The findings hold promise for the likely influence of federal CF&B re
142 the inflammatory and reparative response may hold promise for the prevention of postinfarction heart
143 ipulating the biosynthesis of these peptides hold promise for the remediation of soils and groundwate
144 y with data-driven and mechanistic modeling, hold promise for the systematic interrogation of these c
145  that posaconazole-loading of leukocytes may hold promise for the therapy of IPA.
146  target of rapamycin (PI3K/AKT/mTOR) pathway hold promise for the treatment of breast cancer, but res
147 Efforts to induce physiological angiogenesis hold promise for the treatment of diabetic microvascular
148 to joint inflammation, and anti-DEK aptamers hold promise for the treatment of JIA and other types of
149 h as efflux pumps, are under development and hold promise for the treatment of multidrug resistant in
150                   gamma-Secretase inhibitors hold promise for the treatment of patients with NOTCH1 m
151    Thus, targeting of TCR-related events may hold promise for the treatment of TFH-derived lymphomas.
152 tion and suggest that MEK/ERK inhibitors may hold promise for the treatment of type 2 diabetes.
153            Antisense oligonucleotides (AONs) hold promise for therapeutic correction of many genetic
154 ions used for prevention in older adults may hold promise for those in middle age.
155                                         They hold promise for transforming the current technologies i
156                         Kerr frequency combs hold promise for transforming these lab-scale oscillator
157 entification and isolation of these lineages hold promise for translational medicine aimed at in vivo
158                          Parasitic helminths hold promise for treating inflammatory disorders, so we
159  prevent memory loss in Ts65Dn mice, and may hold promise for treatment in individuals with DS and de
160 naling pathways, and as such, JAK inhibitors hold promise for treatment of autoimmune disorders, incl
161 ese cases is yet missing, but is believed to hold promise for treatment of cancer and prevention of h
162 it light long after cessation of excitation, hold promise for ultrasensitive in vivo imaging because
163 tion studies (GWASs) have been considered to hold promise for unravelling complex relationships betwe
164                                    PROs also hold promise for use in evaluating adherence, adverse ef
165 in their electric and magnetic ground states hold promise for use in next-generation memory devices i
166 ce their cooperation with B cells, and which hold promise for vaccine development.
167 vskite solar cells and lithium-ion batteries hold promise for various potential applications.
168 ey competences in sustainability science and hold promises for other sectors as well.
169 nd designed with additional functionalities, holding promise for system integration.
170                              This phenomenon holds promise for a new generation of capacitors capable
171 al of modern condensed-matter physics, which holds promise for a new generation of electronic/photoni
172 One-dimensional conductive particle assembly holds promise for a variety of practical applications, i
173 mage and deleterious molecular perturbations holds promise for advancing clinical applications.
174 ide detection of intraventricular hemorrhage holds promise for advancing individual care, targeted th
175 des a further indication that TAML catalysis holds promise for advancing water treatment.
176 t construction of truly de novo biocatalysts holds promise for applications in chemical and biochemic
177 truct biological matter from the molecule up holds promise for applications ranging from smart materi
178              Exploiting this spin dependency holds promise for artificial photosynthetic systems requ
179 regulatory T cell (Treg)-based immunotherapy holds promise for autoimmune diseases.
180  new approach for autoantibody detection and holds promise for being used for patient stratification
181 understanding of such vesiculation processes holds promise for better elucidation of human physiology
182 orks under behaving conditions, our approach holds promise for better understanding of healthy and ab
183                               This discovery holds promise for better understanding the normal physio
184 neration of biosensor based detection tools, holds promise for biological science studies.
185                                   The method holds promise for commercial and regulatory residue anal
186 using renewable sources of electrical energy holds promise for converting CO2 to fuels and chemicals.
187                       De novo protein design holds promise for creating small stable proteins with sh
188                  Allosteric drug development holds promise for delivering medicines that are more sel
189 s with intraplaque hemorrhage and ultimately holds promise for detection of high-risk plaques in pati
190 tes appears to phenocopy cancer cells, which holds promise for developing common therapeutics against
191 with a chemical scaffold distinct from these holds promise for developing peripherally active CB1 inv
192 ed to as "enterotypes" or "community types", holds promise for drastically improving personalized med
193  as a new two-dimensional (2D) material that holds promise for electronic and photonic technologies.
194    Targeting these pathological interactions holds promise for eliminating minimal residual disease i
195 ysis of contemporary and resurrected enzymes holds promise for elucidating the origins and activities
196 with histone deacetylase inhibitors (HDACis) holds promise for enhancing cancer immune therapy.
197                   This experimental platform holds promise for exploring exotic physics in fractional
198 t the levels set by European legislation and holds promise for future adaptation to include other myc
199   The tunable binary citrem/SPC nanoplatform holds promise for future development of hemocompatible a
200 ng of colloidal semiconductor nanostructures holds promise for future device concepts in optoelectron
201 perimental mouse model of MPE, a result that holds promise for future efficient therapies against the
202 e, and perhaps D-cycloserine and rapastinel, holds promise for future glutamate-modulating strategies
203                         Electronic detection holds promise for future miniaturized in-situ applicatio
204  compatible with large-scale integration and holds promise for future spintronic devices for informat
205  While challenges still exist, this approach holds promise for gaining new insights into host-pathoge
206 as9 delivery by adeno-associated virus (AAV) holds promise for gene therapy but faces critical barrie
207  facilitates functional genomic research and holds promise for gene therapy.
208                                         tIDS holds promise for high-efficacy personalized neuromodula
209 ing geographical and environmental gradients holds promise for identifying such mechanisms.
210                           Digital technology holds promise for improving access to, and quality of, m
211                      Modeling these findings holds promise for improving CRT outcomes.
212 induced neurons by direct lineage conversion holds promise for in vitro modelling of sporadic Alzheim
213              BACKGROUND AND AIMS: Proteomics holds promise for individualizing cancer treatment.
214 ve haplotype diversity at the rye Sr50 locus holds promise for mining effective resistance genes.
215 enitor cells from pluripotent stem cells and holds promise for modelling haematopoietic disease in hu
216 cilizumab (anti-IL-6 receptor [IL-6R]) which holds promise for modulating multiple immune pathways re
217 ilizing activity of pseudolaric acid B (PAB) holds promise for new anticancer agents.
218 lization of versatile electronic devices and holds promise for next-generation (opto)electronics.
219 y integrated within a larger-bandgap matrix, holds promise for novel electronic and optoelectronic pr
220 ding of natural mineralization processes and holds promise for novel materials design.
221 d aggregated Abeta42 species, this candidate holds promise for novel preclinical AD imaging and thera
222 s mechanism in disease and how its targeting holds promise for novel therapeutics.
223  findings here suggest that the FSC platform holds promise for optimization of anti-cancer combinatio
224                                 This process holds promise for other applications like catalysis and
225 f treatment of graft-versus-host disease and holds promise for other diseases characterized by inflam
226                                This approach holds promise for patients suffering from genetic diseas
227 of normal NCDPs in FECD-affected endothelium holds promise for potential autologous cell therapies.
228 mage data is an active area of research that holds promise for precision medicine, early assessment o
229 f forward and reserve isomerization pathways holds promise for predictably controlling responses of p
230 ers in conjunction with in-depth phenotyping holds promise for providing insights into the pathophysi
231      A brief psychosocial prevention program holds promise for reducing the 1-year incidence of anxie
232 gineering clinically relevant cells in vitro holds promise for regenerative medicine, but most protoc
233 ological agent that can selectively kill SCs holds promise for rejuvenating tissue stem cells and ext
234 st for hydrogen evolution in acidic solution holds promise for replacing scarce and expensive platinu
235 e method for sub-surface tomographic imaging holds promise for several applications in semiconductor
236 ting the FGFBP1 and TGF-beta1 signaling axis holds promise for slowing age- and disease-related degen
237 ion of 6.42% (n=5); consequently, the method holds promise for the analysis of commercial fruit juice
238 nsformations.Plasmon-enhanced photocatalysis holds promise for the control of chemical reactions.
239 topoietic stem cell (HSC)-based gene therapy holds promise for the cure of many diseases.
240  understanding of NAb repertoire development holds promise for the design of both biological diagnost
241 The 3D X-ray structure of these DNA crystals holds promise for the design of new structural motifs to
242 and/or desensitization/inactivation of nAChR holds promise for the development of new antidepressants
243 therapy), making this regulation unique, and holds promise for the development of novel alternative/c
244  RNA-protein interaction in hantaviruses and holds promise for the development of the first anti-hant
245       This precision spectroscopic technique holds promise for the future development of high-through
246    Laser-generated-focused ultrasound (LGFU) holds promise for the high-precision ultrasound therapy
247 essful attempt at engineering heme stability holds promise for the production of stable Hb-based bloo
248 ain pseudospin coherence at room temperature holds promise for the realization of new classical and q
249                              Thus blue light holds promise for the sterilization of clinical surfaces
250 clearance of these cells by senolytic agents holds promise for the treatment of atherosclerosis.
251             Although adoptive T-cell therapy holds promise for the treatment of many cancers, its cli
252                                 Gene therapy holds promise for the treatment of many pathologies of t
253                    This therapeutic strategy holds promise for this AML patient subgroup in future cl
254                    Targeting the JAK pathway holds promise for treating age-related dysfunction.
255                         Nucleic acid editing holds promise for treating genetic disease, particularly
256 and suggests that reprogramming this circuit holds promise for treating opiate addiction.
257 c organic and physical-inorganic chemistries holds promise for tremendous new opportunities in both a
258   Loading viral vectors with cGAMP therefore holds promise for vaccine development.
259 ingual immunotherapy (SLIT) for food allergy hold promise; however, the immunologic mechanisms underl
260                   Although perovskite oxides hold promise in applications ranging from solid oxide fu
261    DNA nanoassemblies, such as DNA origamis, hold promise in biosensing, drug delivery, nanoelectroni
262 ective experience of a rodent, rodent models hold promise in dissecting well-conserved limbic circuit
263 ed at augmenting restoration of the GI tract hold promise in returning cART recipients to full health
264 g functionalized C3 -symmetrical triptycenes hold promise in the design of functional materials.
265  idiopathic pulmonary fibrosis, a number may hold promise in the treatment of diabetic nephropathy, w
266 e cytoplasmic chromatin-mediated pathway may hold promise in treating inflammation-related disorders.
267 ic acid with bone, the proposed nanomedicine hold promises in delivering drug to bone microenvironmen
268 alytic performance toward ethanol oxidation, holding promise in fuel-cell applications.
269       The application of enhancer technology holds promise in accelerating basic neuroscience researc
270 ets, decrease the antibiotic consumption and holds promise in averting antibiotic resistance.
271   The faster responsiveness of this approach holds promise in avoiding hyperglycemia and hypoglycemia
272 medicine and providers of mental health care holds promise in bridging the treatment gap in mental he
273 ndicated (eg, allergy, renal impairment) and holds promise in differentiating tumor progression from
274                    This class of antibiotics holds promise in fighting MRSA infections.
275 nsively decoding these regulatory mechanisms holds promise in getting deeper insights into a variety
276  time period and then degrades or destructs, holds promise in medical implants, reconfigurable electr
277 es to lower aberrant inflammasome activation holds promise in reducing multiple chronic diseases of a
278 in 2D nature of suspended graphene membranes holds promising in numerous technological applications.
279 noninvasive hemoglobin monitoring technology holds promise, it is not yet an acceptable substitute fo
280 ciency, this review will focus on those that hold promise or are already at an advanced stage of test
281 hybrid has high cadmium removal capacity and holds promising prospects for treatment of metal-contami
282                    The results of this study hold promise that AAV-based supplemental gene therapy wi
283 ighly consistent with histology findings and hold promise to accurately characterize the heterogeneou
284 orated with photonic crystal (PC) structures hold promise to address many of the aforementioned chall
285 ined small-molecule inhibitors such as PDZ1i hold promise to advance targeted brain cancer therapy.
286                             SC-Ads therefore hold promise to be more potent vectors and vaccines than
287           Injectable, acellular biomaterials hold promise to limit left ventricular remodeling and he
288 se designs are an underused intervention and hold promise to reduce malaria transmission in sub-Sahar
289                               Flow cytometry holds promise to accelerate antibiotic susceptibility de
290 Thus, the light weight and waterproof design holds promise to advance the next generation of mobile h
291 ter algorithms that improve with experience, holds promise to enable computers to assist humans in th
292 t only a combination of tools and approaches holds promise to end M leprae transmission.
293 , known as 'antenna-reactor' nanostructures, holds promise to expand the scope of chemical reactions
294                                   The latter holds promise to facilitate timely transplantation and o
295                           This approach thus holds promise to identify other transient protein-protei
296 sic science underlying BRCA network function holds promise to maximally exploit genome instability fo
297 alytic hydroamination of alkenes with amines holds promise to rapidly deliver value-added chiral amin
298 unotherapeutic targeting of amyloid deposits holds promise to transform outcomes in systemic amyloido
299               Carbon-ion radiotherapy (CIRT) holds promise to treat inoperable locally-advanced non-s
300  for quantitative proteomics of archaea that holds promise to unravel gene function.

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