ライフサイエンスコーパス: homeobox

1 he 180-base pair DNA fragment comprising the homeobox.

2 The transcription factor caudal-type homeobox 1 (CDX1) is a key regulator of differentiation

3 ed by engrailed 1 (En1) and developing brain homeobox 1 (Dbx1).

4 In distal-less homeobox 1 (Dlx1(-/-)) mice with late-onset interneuron

5 n of the transcription factor genomic screen homeobox 1 (gsx1) produced profound defects in PPI in ze

6 sis-associated genes, we identified Iroquois homeobox 1 (IRX1).

7 ion with overexpression of its cofactor meis homeobox 1 (MEIS1) .

8 P1; from mesoderm to cardiac mesoderm), meis homeobox 1 (MEIS1) and GATA-binding protein 4 (GATA4) (p

9 We show that muscle segment homeobox 1 (MSX1) acts exclusively in collateral arteria

10 tor 4 alpha (Hnf4a), which competed with NK2 homeobox 1 (Nkx2.1) for binding to forkhead box A2 (Foxa

11 NK3 homeobox 1 (Nkx3.1), a transcription factor expressed in

12 of the homeodomain transcription factor NK6 homeobox 1 (Nkx6.1) in rat pancreatic islets induces bet

13 ncreatic and duodenal homeobox 1 (PDX1), NK6 homeobox 1 (NKX6.1), forkhead box A2 (FOXA2), and NK2 ho

14 Pre-B cell leukemia homeobox 1 (Pbx1)-d is a dominant-negative splice isofor

15 Although the pancreatic duodenal homeobox 1 (Pdx-1) transcription factor is known to play

16 he beta cell markers pancreatic and duodenal homeobox 1 (Pdx1) and paired box 4 (Pax4).

17 iverse functions for pancreatic and duodenal homeobox 1 (PDX1), a transcription factor indispensable

18 of cells expressing pancreatic and duodenal homeobox 1 (PDX1), most pancreatic cells are refractory

19 in sites occupied by pancreatic and duodenal homeobox 1 (PDX1), NK6 homeobox 1 (NKX6.1), forkhead box

20 Pituitary homeobox 1 (PITX1) functions as a tumor suppressor in he

21 In this study, we identify Prospero-related homeobox 1 (Prox1) as a novel co-repressor of the retino

22 nchymal lineage as defined by Paired related homeobox 1 (Prx).

23 ltant induction of zinc-finger E-box-binding homeobox 1 (ZEB1) as mediated by microRNA deregulation.

24 nduced by the EMT, zinc finger E-box binding homeobox 1 (ZEB1) binds and silences IRF1.

25 related to the mesoderm stage; E-box-binding homeobox 1 (ZEB1) in the module correlated with postcard

26 ased expression of zinc finger E-box binding homeobox 1 (ZEB1) is associated with tumor grade and met

27 ough activation of zinc finger E-box binding homeobox 1 (ZEB1) sensitized tumor cells to the antiprol

28 ression of VIM and zinc finger E-box binding homeobox 1 (ZEB1), aberrant cell motility, and increased

29 n (EMT) regulator, Zinc finger E-box binding homeobox 1 (ZEB1), or overexpression of the ZEB1-repress

30 mutated (ATM) and zinc finger E-box binding homeobox 1 (ZEB1).

31 ranscription factors pancreatic and duodenal homeobox 1 and sterol regulatory element-binding protein

32 s of function mutations/deletions in the PBX homeobox 1 gene (PBX1), a gene known to have a crucial r

33 se; (5) upregulating pancreatic and duodenal homeobox 1 gene expression and the insulin secretagogue

34 Akt phosphorylation, pancreatic and duodenal homeobox 1 nucleocytoplasmic shuttling, and transcriptio

35 e expression driven by the pancreas-duodenum homeobox 1 promoter is abundant in several hypothalamic

36 oR-HDAC3 complex as well as Prospero-related homeobox 1 protein (PROX1).

37 sess the effect of zinc finger E box-binding homeobox 1 transcription factor (ZEB1), siRNA-mediated k

38 nd decreased Zeb1 (zinc finger E-box-binding homeobox 1) and promoted beta cell apoptosis as measured

39 ain transcription factor gene CUX1 (cut-like homeobox 1) in ~1-5% of various tumors.

40 transgene driven by the Prx1 (paired related homeobox 1) promoter.

41 ind that the ZEB1 (zinc finger E-box binding homeobox 1) transcription factor activity in highly mese

42 meodomain-containing protein HLX1 (H2.0-like homeobox 1).

43 y up-regulation of zinc finger E box-binding homeobox 1, loss of E-cadherin, up-regulation of cadheri

44 elium derive from embryonic, endodermal, NK2 homeobox 1-expressing (NKX2-1+) precursor cells.

45 ription regulator, zinc finger E-box binding homeobox 1.

46 ve tumor suppressor roles in T-cell leukemia homeobox 1/3-transformed human T-ALL cell lines and NOTC

47 and enhancer of split 1/pancreatic duodenal homeobox-1 (Hes-1/PDX-1) in mature cholangiocytes determ

48 vely heterodimerize with pre-B-cell leukemia homeobox-1 (Pbx1).

49 Mutations in pancreatic duodenal homeobox-1 (PDX1) are associated with diabetes in humans

50 Pancreatic duodenal homeobox-1 (Pdx1), a transcription factor required for p

51 The Zinc-finger E-box-binding Homeobox-1 (ZEB1) is a transcription factor that promote

52 ing of the proadipogenic pre-B-cell leukemia homeobox-1/homeobox 9 complex.

53 array screening reveals that caudal-related homeobox 2 (Cdx2) and Rbl2/p130 are remarkably suppresse

54 tivity studies, we identified caudal-related homeobox 2 (CDX2) transcription factor as a positive reg

55 ation of the TE master regulator Caudal-type homeobox 2 (Cdx2).

56 Distal-less homeobox 2 (Dlx2) acted downstream of Ascl1 in promoting

57 e transcriptional determinants, including GS Homeobox 2 (Gsx2) and Early B-cell factor 1 (Ebf1).

58 show that the transcription factor Ladybird homeobox 2 (Lbx2) positively controls the Wnt/beta-caten

59 Y box (SOX) binding sites, that SOX9 and LIM homeobox 2 (LHX2) are coexpressed in the nuclei of matur

60 n mice to investigate the role of the TF LIM homeobox 2 (Lhx2) in this process and report that in con

61 1 (NKX6.1), forkhead box A2 (FOXA2), and NK2 homeobox 2 (NKX2.2) - factors that co-occupy active enha

62 ectives on how the transcription factors NK2 homeobox 2 (NKX2.2), paired box 6 (PAX6), and LIM domain

63 lopmental transcription factor orthodenticle homeobox 2 (Otx2) as an upstream mediator of these endur

64 SOX9 acts synergistically with orthodenticle homeobox 2 (OTX2) to activate the RPE65 and retinaldehyd

65 e validated new OGT targets is Orthodenticle homeobox 2 (OTX2), a transcription factor critical for b

66 ed with a similar reduction in orthodenticle homeobox 2 (Otx2), which is restricted to VTA neurons at

67 xogenous (eGFP) or endogenous [orthodenticle homeobox 2 (Otx2)] genes can be efficiently targeted to

68 as upregulated, one of which was POU class 3 homeobox 2 (Pou3f2).

69 wo novel candidate driver genes, POU class 4 homeobox 2 (POU4F2) (mutated in 9 [8.9%] samples) and ZK

70 in protein ligase (Toporsa); and POU class 6 homeobox 2 (Pou6f2), we uncovered that sumoylation regul

71 rms were directly targeted by Visual Systems Homeobox 2 (VSX2), a transcription factor involved in pa

72 we identify the TF zinc finger E box-binding homeobox 2 (Zeb2) to play a crucial role in regulating D

73 box 10 (SOX10) and zinc finger E-box binding homeobox 2 (ZEB2).

74 e demonstrate that zinc-finger E-box-binding homeobox 2 (Zeb2, also called Sip1) transcription factor

75 cytoplasmic calcineurin-dependent 1 and LIM homeobox 2 during normal hair cycling in adult skin.

76 uction of transcription factor orthodenticle homeobox 2 expression.

77 tely 8 weeks, before which Nirenberg and Kim homeobox 2.2 (NKX2.2) was not observed in the pancreatic

78 previously identified Zhx2 (zinc fingers and homeoboxes 2) as a regulator of numerous liver-enriched

79 Pituitary homeobox-2 (PITX2) plays a substantial role in the devel

80 RTqPCR for paired-like homeobox 2b (PHOX2B), tyrosine hydroxylase (TH), and dou

81 for the poorly characterized T-cell leukemia homeobox 3 (TLX3) TF was confirmed with gel shift assay

82 homeodomain transcription factor distal-less homeobox 3 gene (DLX3) is required for hair, tooth and s

83 nscription factor 1 beta and T-cell leukemia homeobox 3.

84 zed by the aberrant expression of the Double homeobox 4 (DUX4) transcription factor leading to altere

85 pancy and transcriptional activity of double homeobox 4 (DUX4), a protein whose aberrant expression h

86 xpression of the transcription factor Double Homeobox 4 (DUX4).

87 ermore, the homeodomain proteins distal-less homeobox 5 (DLX5) and DLX6 reciprocally inhibit BMP/H2-m

88 ed CHD by repressing Isl1 and activating NK2 homeobox 5 (Nkx2.5), resulting in decreased cell prolife

89 WUSCHEL-RELATED HOMEOBOX 5 (WOX5), which is specifically expressed in th

90 on the transcription factor WUSCHEL-RELATED HOMEOBOX 5 (WOX5), which is specifically expressed in th

91 and atrial conduction, including Nkx2-5 (NK2 homeobox 5), Tbx3, and Tbx5 are dysregulated.

92 use of existing transgenic mouse lines, Lim homeobox 6 (Lhx6)-Cre and parvalbumin (PV)-Cre, to defin

93 (PV)-expressing GPe neurons over that of Lim homeobox 6 (Lhx6)-expressing GPe neurons, restores movem

94 This study demonstrates that the LIM homeobox 8 (Lhx8) transcription factor regulates choline

95 proadipogenic pre-B-cell leukemia homeobox-1/homeobox 9 complex.

96 associated with hepatocyte nuclear factor 1 homeobox A (Hnf1a) and hepatocyte nuclear factor 4A (Hnf

97 hylates its own promoter and the promoter of homeobox A (HOXA) genes, enhancing its own expression an

98 In silico prediction suggests that homeobox A1 (HOXA1) is a direct target of miR-181c.

99 Homeobox a1 (Hoxa1) is one of the most rapidly induced g

100 ated that inhibition of miR-181c upregulates homeobox A1 (HOXA1), which is important for hepatocyte g

101 t 6, ecotropic viral integration site 1, and homeobox A11.

102 entified both common gene targets, including homeobox A5 (HOXA5), which could account for some of the

103 Homeobox A9 (HOXA9) is a homeodomain-containing transcri

104 ectly and indirectly by decreasing levels of homeobox A9 (HOXA9).

105 Among them, we found HOXA9 (Homeobox A9), a putative oncogene in leukaemia, which al

106 y and caused differentiation of MLL-AF9- and homeobox A9-driven (HOXA9-driven) leukemias.

107 ther through the expression of KNOTTED1-LIKE HOMEOBOX and other indeterminacy genes, altering known d

108 is significant co-occupancy of Nanog (Nanog homeobox) and Hoxa1 on many common target sites, and the

109 Interestingly, aristaless-related homeobox (ARX), a homeobox-containing transcription fact

110 motif-pairs with constrained spacing-Ets and Homeobox as well as Ets and E-box.

111 The MLL-Homeobox axis we identified significantly contributes to

112 disorders, including the 17q12 deletion HNF1 homeobox B (HNF1B) and triple X syndromes in 19 of 419 u

113 variants in the hepatocyte nuclear factor 1 homeobox B (HNF1B) gene are associated with the risk of

114 n polycystic kidney disease 1 (PKD1) or HNF1 homeobox B (HNF1B), inherited from the unaffected parent

115 c livers express hepatocyte nuclear factor 1 homeobox B (HNF1beta).

116 e regulatory factor 6 (RFX6) gene, increased homeobox B13 (HOXB13) binding at the rs339331 region, an

117 screening, identification of a single gene, homeobox B5 (Hoxb5, also known as Hox-2.1), with express

118 The Caudal-Related Homeobox (Cdx) protein family is a group of the transcri

119 Here, we show that the mouse Caudal-related homeobox (Cdx) proteins (mCdx1, mCdx2, and mCdx4) are al

120 In mammals, there are three Dlx homeobox clusters with closely located gene pairs (Dlx1/

121 The homeobox coding DNA may therefore have a secondary funct

122 The most notable examples of homeobox containing genes are the Hox genes, arranged on

123 strate that functional loss, or gain, of the homeobox-containing gene barx1 produces gain, or loss, o

124 ouse embryos represses the expression of the homeobox-containing genes Pax3 and Cdx2 at the dorsal po

125 tingly, aristaless-related homeobox (ARX), a homeobox-containing transcription factor critical for th

126 enome-wide association studies indicated the homeobox-containing transcription factor Engrailed-2 (En

127 VAX1 encodes a homeobox-containing transcription factor identified as a

128 t of the 39 mammalian Hox genes and in other homeobox-containing transcription factors.

129 The use of cone-rod homeobox (CRX) transcription factor messenger RNA for MD

130 We demonstrate that the homeobox DNA has a characteristic 3-base-pair periodicit

131 ed this phenotype to deleterious nonsense or homeobox domain missense mutations in NKX6-2.

132 inactivating mutations affecting the NKX6-2 homeobox domain.

133 The homeobox encodes a DNA-binding domain found in transcrip

134 eal a novel requirement for Prospero-related homeobox factor 1 (Prox1) during mouse heart development

135 We identified the PRRX1 homeobox factor as a repressor of PPARG2 expression in a

136 s glucocorticoid receptor and brain-specific homeobox factor.

137 apping function and expression among various homeobox factors.

138 e WUS-box, which is conserved in WUS-related HOMEOBOX family members, and the ethylene-responsive ele

139 NKX2 homeobox family proteins have a role in cancer developme

140 Iroquois homeobox gene 3 (Irx3) is a transcription factor of the

141 two transcription factors: Iroquois-related homeobox gene 3 (Irx3) posterior to the ZLI, and paired

142 Here, we identified the conserved NK-2 homeobox gene ceh-24 to be crucially required for flippi

143 f polycomb repression such as the Hox and NK homeobox gene clusters.

144 are undifferentiated and aberrantly express homeobox gene clusters.

145 The homeobox gene Emx1 is expressed in three guanylate cycla

146 lication, including upregulation of proximal homeobox gene expression and silencing of distal-associa

147 Together our results highlight how homeobox gene families evolved during eukaryote evolutio

148 encephalon, members of the distal-less (Dlx) homeobox gene family are expressed in, and regulate the

149 lustered HOX genes, the role of nonclustered homeobox gene family members in hematopoiesis and leukem

150 e found that the hematopoietically expressed homeobox gene Hhex is overexpressed in acute myeloid leu

151 y connected, at megabase distances, with the homeobox gene IRX3.

152 ate that the Zfhx1b (Sip1, Zeb2) zinc finger homeobox gene is required in the MGE, directly downstrea

153 Pitx2 is the homeobox gene located in proximity to the human 4q25 fam

154 The NKX3.1 homeobox gene plays essential roles in prostate differen

155 m under the control of the pancreas duodenal homeobox gene promoter.

156 mesters to determine methylation patterns of homeobox gene promoters across gestation.

157 gut epithelium requires the activity of the homeobox gene Prox1.

158 ow that the proximal promoter from the Rhox5 homeobox gene recruits polymerase II and begins elongati

159 that evolution of an enhancer element in the homeobox gene REDUCED COMPLEXITY (RCO) altered leaf shap

160 ed the lineage of selected Emx2+ [vertebrate homeobox gene related to Drosophila empty spiracles (ems

161 ibuted greatly to the expansion of the grape homeobox gene superfamily.

162 eltamir larvae derepress a network of direct homeobox gene targets in the posterior ventral nerve cor

163 ls of ovarian cancer that expressed HOXA9, a homeobox gene that is associated with poor prognosis in

164 n specifically prevents CBs that express the homeobox gene tinman from completing their dorsal migrat

165 The homeobox gene Tshz1 is expressed in a unique patchy patt

166 llaborating transcription factors is the POU homeobox gene unc-86, which collaborates with ttx-3 to d

167 oth genes requires the early activity of the homeobox gene zerknullt (zen).

168 The hematopoietically expressed homeobox gene, Hhex, is a transcription factor that is i

169 nvestigated the role of the homeodomain-only homeobox gene, HOPX, in the pathogenesis of HNSCC.

170 of DLX4, a transcription factor encoded by a homeobox gene, is associated with reduced survival of ov

171 t SHOOT MERISTEMLESS, a class I KNOTTED-LIKE HOMEOBOX gene, is likely to play a role in PLB regenerat

172 e homeodomain transcription factor 2 (Pitx2) homeobox gene.

173 between the CLAVATA pathway and the WUSCHEL homeobox gene.

174 into Hoxa9 impaired leukemogenicity of this homeobox gene.

175 6 (KNAT6) together with ARABIDOPSIS THALIANA HOMEOBOX GENE1 (ATH1).

176 d transcription factors, including dozens of homeobox genes and other genes implicated in cancer.

177 nvolved in intestinal development, including homeobox genes and targets of the Polycomb repressive co

178 TMERISTEMLESS (STM) and BREVIPEDICELLUS (BP) homeobox genes and their ability to modify leaf form.

179 The Six homeobox genes are essential developmental regulators or

180 Our results strongly suggest that human RHOX homeobox genes are under an epigenetic control mechanism

181 velopmental transcription factors, including homeobox genes belonging to the Antennapedia (ANTP) clas

182 architecture and phylogenetic analyses grape homeobox genes can be classified into eleven subfamilies

183 Homeobox genes constitute a large family of genes widely

184 Analyses of homeobox genes during development show that some of thes

185 We hypothesized that Dlx1, Dlx2 and Brn3b homeobox genes function in parallel intrinsic pathways t

186 am in the cell of origin, which includes the homeobox genes Hoxa9 and Meis1 as key components.

187 erize the expression patterns of a set of 49 homeobox genes in the MOE with in situ hybridization.

188 Genome clustering of homeobox genes is often thought to reflect arrangements

189 Homeobox genes regulate embryonic and placental developm

190 We show that Dlx1/Dlx2 homeobox genes regulate GABA synthesis during forebrain

191 ontrast, expression of TCP, TPR and KNOTTED1 homeobox genes showed a sustained down-regulation.

192 The tissue-specific expression patterns of homeobox genes suggested roles in both vegetative and re

193 The X-linked RHOX cluster encodes a set of homeobox genes that are selectively expressed in the rep

194 attenuate the potential of stem cell active homeobox genes to acquire oncogenic properties.

195 Most homeobox genes were hypo-methylated throughout gestation

196 licated by the top DMRs were protocadherins, homeobox genes, MAPKs and ryanodine receptors.

197 Two related BEL1-like homeobox genes, PENNYWISE (PNY) and POUND-FOOLISH (PNF),

198 alyse the chromosomal organization of the NK homeobox genes, presumed to be part of a single cluster

199 and sequence analyses of their Hox and other homeobox genes, which encode crucial transcription facto

200 anscription factor of the Iroquois family of homeobox genes.

201 ified processes, including transcription and homeobox genes.

202 ion factor HHEX (hematopoietically expressed homeobox) has been repeatedly linked to type 2 diabetes

203 a downstream effector molecule of H2.0-like homeobox (HLX), a gene functionally relevant for AML pat

204 e we uncover unique RNA regulons embedded in homeobox (Hox) 5' untranslated regions (UTRs) that confe

205 activation of most developmentally critical homeobox (Hox) a-d genes.

206 miRNAs involved in cell differentiation and Homeobox (Hox) gene control.

207 etermination of defined roles for endogenous homeobox (Hox) genes in adult hematopoietic stem and pro

208 pes that result from oncogenic activation of homeobox (HOX) transcription factors are associated with

209 todermal ridge (AER), whereas an alternative Homeobox (Hox)-Fibroblast growth factor (Fgf)-Wingless t

210 tosis of AML cells through inhibition of the homeobox (HOX)A9 oncogene expression, reducing the trans

211 biquitylation of H2A and thereby derepresses homeobox HOXC5 and HOXC13 gene expression.

212 re we analysed complete suites of ANTP-class homeoboxes in two calcareous sponges, Sycon ciliatum and

213 The knotted1 (kn1) homeobox (knox) gene family was first identified through

214 hich ectopic expression of the KNOTTED1-like Homeobox (KNOX) gene, BKn3, causes inverted polarity of

215 r unknown role for the Class I KNOTTED1-LIKE HOMEOBOX (KNOX) gene, TKN4, in specifying the formation

216 KNOTTED1-LIKE HOMEOBOX (KNOX) genes are important regulators of merist

217 anscription factors such as the KNOTTED-LIKE HOMEOBOX (KNOX) genes, the hormone auxin, and miRNAs.

218 phology of RNAi lines resemble KNOTTED1-LIKE HOMEOBOX (KNOX) mutants, consistent with a mechanistic c

219 Class I KNOTTED-LIKE HOMEOBOX (KNOX) proteins regulate development of the mul

220 factors including the Class I KNOTTED1-LIKE HOMEOBOX (KNOXI) proteins, auxin, and cytokinin are know

221 kpoint (MEC)-3 (LIM)-homeobox subfamily, LIM homeobox (Lhx)6 and -8 are remarkably conserved and invo

222 e present study, we identified a total of 73 homeobox-like genes in the grapevine genome and analyzed

223 tional activation of multiple PRC2-repressed homeobox master regulators and their regulated developme

224 by leveraging methylated CpG sites in a LIM homeobox member gene (LHX9), which may have a role in th

225 We report that mohawk homeobox (Mkx), a tendon-specific transcription factor,

226 Cone-rod homeobox mRNA was expressed in all tumors (relative expr

227 Uterine inactivation of muscle segment homeobox (Msx) genes alters epithelial cell junction pro

228 xpression of regenerative genes, such as Msh homeobox (Msx) genes, are absent in this animal group.

229 Pre-B-cell leukemia homeobox (PBX) and myeloid ecotropic viral integration s

230 Pre-B-cell leukemia homeobox (PBX) transcription factors are known to regula

231 Pre-B-cell leukemia homeobox (Pbx)-regulating protein-1 (Prep1) is a ubiquit

232 ability to initiate Pancreatic and duodenal homeobox (Pdx1) expression for the first time.

233 related orphan receptor beta, brain-specific homeobox/POU domain protein 3b, Ets variant gene 1, subs

234 or and human diabetes gene pancreas/duodenum homeobox protein 1 (Pdx1) regulates beta-cell survival a

235 ic identity through upregulation of prospero homeobox protein 1 (PROX1), the master regulator of lymp

236 and the transcription factor paired-related homeobox protein 1 (PRRX1; alias PRX-1), a newly identif

237 type, expressing lymphatic markers (prospero homeobox protein 1 and vascular endothelial growth facto

238 results in attenuated expression of prospero homeobox protein 1 during development.

239 r 3 (VEGFR-3) but not of LYVE-1 and prospero homeobox protein 1.

240 cine zipper protein (HD-ZIP)-encoding genes: HOMEOBOX PROTEIN 21 (HB21), HOMEOBOX PROTEIN 40 (HB40),

241 -encoding genes: HOMEOBOX PROTEIN 21 (HB21), HOMEOBOX PROTEIN 40 (HB40), and HOMEOBOX PROTEIN 53 (HB5

242 N 21 (HB21), HOMEOBOX PROTEIN 40 (HB40), and HOMEOBOX PROTEIN 53 (HB53).

243 cgn), specificity protein 8 (SP8) and/or LIM homeobox protein 7 (Lhx7) separates striatal CR+ interne

244 Our previous study of LPS predicted homeobox protein A5 (HOXA5) as a target of miR-26a-2, an

245 Mutations in the cone-rod-homeobox protein CRX are typically associated with domin

246 up-regulated Ape1 via a transcription factor homeobox protein Hox-A5-dependent mechanism.

247 dings suggest that these variants affect the homeobox protein IRX3.

248 We report here that the intestine-specific homeobox protein ISX is critical to control the metaboli

249 e for beta-catenin-mediated expansion of LIM/homeobox protein Lhx2(+) cells, in the stem/early progen

250 Here we show that homeobox protein Mohawk (Mkx) is a key transcription fac

251 actor-binding sites for ARABIDOPSIS THALIANA HOMEOBOX PROTEIN5, LIM1 (for LINEAGE ABNORMAL11, INSULIN

252 tative NKE elements, possible targets of NK2 homeobox proteins like the essential islet transcription

253 Further, residual homeobox pseudogenes are observed in the three lineages.

254 The retinal anterior homeobox (rax) gene encodes a transcription factor neces

255 The X-linked reproductive homeobox (RHOX) gene cluster encodes transcription facto

256 sl)-1/mitosis entry checkpoint (MEC)-3 (LIM)-homeobox subfamily, LIM homeobox (Lhx)6 and -8 are remar

257 scripts can be spliced to produce intergenic homeobox swaps.

258 ement of membrane molecules regulated by the homeobox TF Even-skipped (Eve), the major determinant of

259 creatic transcription factor 1a (Ptf1a), the homeobox TF-Lbx1 and the Lim-homeodomain (Lim-HD), and T

260 i revealed a striking clustering of distinct homeobox TFBS.

261 ally activate CCAAT displacement protein/cut homeobox transcription factor (CUX1).

262 ved that the retina and anterior neural fold homeobox transcription factor (Rax) is selectively expre

263 brainstem expression program, including LIM homeobox transcription factor 1 beta and T-cell leukemia

264 Mutations in the LIM homeobox transcription factor 1-beta (LMX1B) are a cause

265 activation and/or maintenance of LMX1A (LIM homeobox transcription factor 1alpha) and PITX3 (paired-

266 e validate and assess the mechanism by which homeobox transcription factor A1 (HOXA1), a pro-invasion

267 Here we show that deregulation of the homeobox transcription factor gene DUX4 and the ETS tran

268 d signaling the expression of the intestinal homeobox transcription factor ISX.

269 d signals, directly activates the LIM domain homeobox transcription factor Lhx1 in the visceral endod

270 ruitment, in part by directly activating the homeobox transcription factor Lhx1.

271 Hcrt neurons in vivo, we identified the LIM homeobox transcription factor Lhx9 as necessary and suff

272 Using an unbiased screen, we identified the homeobox transcription factor MEIS2 as an endogenous sub

273 We show that the binding of homeobox transcription factor OTX2 at the Nrl promoter w

274 n chromosome 4q25, close to the gene for the homeobox transcription factor PITX2.

275 This includes Meis1, a TALE class homeobox transcription factor required for B-cell develo

276 viously identified the signaling pathways of homeobox transcription factor STIMPY and metabolic sugar

277 licated in senescence, we identified DLX2, a homeobox transcription factor that has been shown to be

278 Lhx1 encodes a LIM homeobox transcription factor that is expressed in the p

279 DUX4 is a double homeobox transcription factor that is normally expressed

280 mportantly, we identify Lhx2 (encoding a LIM/homeobox transcription factor) as a direct NF-kappaB tar

281 We show that Abdominal-B (Abd-B), a homeobox transcription factor, is required in developing

282 We report that zinc finger and homeobox transcription factor-1 (Zeb1), a master regulat

283 expression of the Zinc finger E-box binding homeobox transcription factor-2 (ZEB2) is correlated wit

284 Genes encoding homeobox transcription factors are mis-expressed in the

285 ave drawn attention to the importance of Alx homeobox transcription factors during craniofacial devel

286 The role of Homeobox transcription factors during fin and limb devel

287 ansformation by regulating the expression of homeobox transcription factors in mice.

288 opment in grape revealed that genes encoding homeobox transcription factors were differentially regul

289 In Hand2-overexpressing mutants, non-Hox homeobox transcription factors were dysregulated.

290 We have identified two planarian homeobox transcription factors, Smed-nkx2.1 and Smed-arx

291 al and abaxial domains and maintained by WOX homeobox transcription factors, whereas other marginal e

292 Epidermal-specific deletion of the homeobox transcription regulator DLX3 disrupts keratinoc

293 VentX is a human homeobox transcriptional factor that regulates prolifera

294 how that SIX1, a member of the SIX family of homeobox transcriptional factors, is a novel repressor o

295 t that WOX7, a member of the WUSCHEL related homeobox (WOX) family transcription factors, inhibits la

296 ample of this is seen in the WUSCHEL-RELATED HOMEOBOX (WOX) gene family, named after the Arabidopsis

297 The Medicago truncatula WUSCHEL-related homeobox (WOX) gene, STENOFOLIA (STF), plays a key role

298 The WUSCHEL related homeobox (WOX) genes play key roles in stem cell mainten

299 The WUSCHEL-RELATED HOMEOBOX (WOX) genes WOX1 and PRS are expressed in the l

300 h a classical feedback circuit involving the homeobox WUSCHEL (WUS) gene and the CLAVATA (CLV) gene s