ライフサイエンスコーパス: homeobox gene

1 into Hoxa9 impaired leukemogenicity of this homeobox gene.

2 ng the proximal promoter (Pp) from the Rhox5 homeobox gene.

3 1 genes, whereas D283 overexpresses the OTX2 homeobox gene.

4 n the 3'-UTR of a target of lsy-6, the cog-1 homeobox gene.

5 ntained the orthodenticle homologue 2 (OTX2) homeobox gene.

6 e homeodomain transcription factor 2 (Pitx2) homeobox gene.

7 between the CLAVATA pathway and the WUSCHEL homeobox gene.

8 ified processes, including transcription and homeobox genes.

9 thin the arcuate that express Nkx2.1 and Dlx homeobox genes.

10 longs to the highly divergent H2.0 family of homeobox genes.

11 throid differentiation and downregulation of homeobox genes.

12 ncluded loci located upstream of a number of homeobox genes.

13 anscription factor of the Iroquois family of homeobox genes.

14 ncluding overexpression of the Gsx1 and Gsx2 homeobox genes.

15 that GLP-1 increases pancreatic and duodenal homeobox gene-1 and Foxa2 expression and inhibits FoxO1

16 restored by expression of the paired-related homeobox gene-1 protein.

17 upregulation of palladin, and paired-related homeobox gene-1 protein.

18 Mutations of the pancreatic duodenal homeobox gene-1, Pdx1, cause heritable diabetes in human

19 Iroquois homeobox gene 3 (Irx3) is a transcription factor of the

20 Here we show that Iroquois homeobox gene 3 (Irx3) is critical for efficient conduct

21 two transcription factors: Iroquois-related homeobox gene 3 (Irx3) posterior to the ZLI, and paired

22 on properties of CTCF at the human and mouse homeobox gene A (HOXA) loci.

23 FL, approximately 150 kb distal to the Pitx2 homeobox gene, a developmental left-right asymmetry (LRA

24 The unc-42 homeobox gene also regulates AVA and AVE identity; howev

25 of the loss-of-function alleles of the cog-1 homeobox gene, an inducer of the fate of the gustatory n

26 In mice, the Crx cone-rod homeobox gene and Math5 are expressed shortly after cell

27 ect regulation of the EC phenotype by GAX, a homeobox gene and negative transcriptional regulator of

28 There was an overrepresentation of homeobox genes and 31% of the most commonly methylated g

29 d transcription factors, including dozens of homeobox genes and other genes implicated in cancer.

30 nvolved in intestinal development, including homeobox genes and targets of the Polycomb repressive co

31 TMERISTEMLESS (STM) and BREVIPEDICELLUS (BP) homeobox genes and their ability to modify leaf form.

32 d for transcription factors (including other homeobox genes) and genes participating in hormonal path

33 nown as Nkx2.1 (related to the NK-2 class of homeobox genes) and T/ebp (thyroid-specific enhancer-bin

34 ts two to four and for the activation of the homeobox gene apterous, the Zinc-finger gene rotund and

35 We cloned a Populus Class 1 KNOX homeobox gene, ARBORKNOX1 (ARK1), which is orthologous t

36 l characterization of a Populus class-I KNOX homeobox gene, ARBORKNOX2 (ARK2), which we show influenc

37 e mice, we tested whether the Engrailed (En) homeobox genes are a common genetic substrate regulating

38 Increasing evidence indicates that many homeobox genes are aberrantly expressed in cancers, and

39 The Six homeobox genes are essential developmental regulators or

40 Moreover, KDM6A- and KDM6B-responsive Homeobox genes are expressed at significantly higher lev

41 Dlx5 and Dlx6 homeobox genes are expressed in developing and mature co

42 ch members of the class-1 KNOX sub-family of homeobox genes are expressed.

43 Homeobox genes are potentially useful as DNA methylation

44 Our results strongly suggest that human RHOX homeobox genes are under an epigenetic control mechanism

45 Although clustered homeobox genes are well-characterized targets of MLL and

46 Mutations in the X-linked aristaless-related homeobox gene (ARX) have been linked to structural brain

47 Grg3 and HDAC1 to the methylated Aristaless homeobox gene (Arx) promoter in beta cells.

48 We have identified the Engrailed (En) homeobox genes as being crucial to producing the distinc

49 log of the vertebrate Xenopus Vent family of homeobox genes, as a novel Wnt repressor and a putative

50 The transcription factor HB9, encoded by the homeobox gene B9 (HLXB9), is involved in the development

51 The Nirenberg and Kim homeobox gene Bapx1 (Nkx3-2) has an established role in

52 ene spineless, and for the repression of the homeobox gene Bar and the putative transcription factor

53 velopmental transcription factors, including homeobox genes belonging to the Antennapedia (ANTP) clas

54 s with PRC2 and recruits this complex to the homeobox genes BREVIPEDICELLUS and KNAT2 to stably silen

55 igate in vivo roles of a murine hypothalamic homeobox gene, Bsx, we generated and analyzed two mutant

56 ecular analyses of a newly identified murine homeobox gene, Bsx/Bsx1a, that is expressed in the devel

57 architecture and phylogenetic analyses grape homeobox genes can be classified into eleven subfamilies

58 s is in particular found for the caudal-type homeobox genes (Cdx) genes, known to act as upstream reg

59 n of stem-like cells and enterocytes via the homeobox gene CDX1.

60 significant downregulation of a caudal type homeobox gene, Cdx2, leading to obvious villus dysmorpho

61 t by influencing expression of an intestinal homeobox gene, Cdx2.

62 Here, we identified the conserved NK-2 homeobox gene ceh-24 to be crucially required for flippi

63 We report here that the NK-2 class homeobox gene ceh-51 is a direct target of TBX-35 and at

64 expression and regulation of the C. elegans homeobox gene ceh-63, which encodes a single-homeodomain

65 at this cluster was embedded within a larger homeobox gene cluster, the Super-Hox cluster, in the anc

66 ox5, the founding member of a large X-linked homeobox gene cluster.

67 bryonic stem (ES) cells is the X-linked Rhox homeobox gene cluster.

68 f polycomb repression such as the Hox and NK homeobox gene clusters.

69 are undifferentiated and aberrantly express homeobox gene clusters.

70 ession activation by nhr-67 of the Nkx6-type homeobox gene cog-1, an inducer of ASER fate, that is in

71 The homeobox genes comprise a large gene superfamily charact

72 zinc finger-homeodomain (ZF-HD) subfamily of homeobox genes, consisting of 14 members in Arabidopsis.

73 Homeobox genes constitute a large family of genes widely

74 Homeobox genes control developmental patterning and are

75 Homeobox genes convey positional information in embryos

76 to derepressed genes, including a number of homeobox genes critical for immune system, brain and cra

77 In mice lacking the cone-rod homeobox gene (Crx), photoreceptors fail to establish no

78 e PI placode and its derivatives express the homeobox gene Dchx1 and can be followed until the late p

79 Nobox (newborn ovary homeobox gene) deficiency disrupts early folliculogenesi

80 To our knowledge, Gax is the first homeobox gene described that inhibits NF-kappaB activity

81 meobox 1 (LBX1), a developmentally regulated homeobox gene, directs expression of the known EMT induc

82 The distal-less homeobox gene (dlx) 5 encodes a transcription factor tha

83 Mice lacking the Dlx1 and Dlx2 homeobox genes (Dlx1/2 mutants) have severe deficits in

84 nt literature claimed that the developmental homeobox gene DLX5 is imprinted and that its imprinting

85 Analyses of homeobox genes during development show that some of thes

86 ssed in FSHD myoblasts, including the double homeobox genes DUX4 and DUX4c.

87 The homeobox gene egl-5 has been shown to regulate the migra

88 beta-catenin homolog bar-1 or the downstream homeobox gene egl-5 results in a defective response and

89 The homeobox gene Emx1 is expressed in three guanylate cycla

90 Homeobox genes encode transcription factors notable for

91 Homeobox genes encode transcription factors that are ess

92 Homeobox genes encode transcription factors that control

93 Homeobox genes encode transcription factors that play im

94 Homeobox genes encode transcription factors which functi

95 Homeobox genes encode transcription factors whose expres

96 Homeobox genes encode transcriptional regulators that co

97 red to transgenics, where the paired-related homeobox gene enhancer or the osteocalcin promoter direc

98 A number of homeobox genes expressed in reproductive tissues have be

99 lication, including upregulation of proximal homeobox gene expression and silencing of distal-associa

100 onserved paradigm to epigenetically regulate homeobox gene expression during development.

101 is further required for KNOX (knotted1-like homeobox) gene expression and localized auxin activity m

102 Together our results highlight how homeobox gene families evolved during eukaryote evolutio

103 uring the past decade it was recognized that homeobox gene families such as the clustered Hox genes p

104 encephalon, members of the distal-less (Dlx) homeobox gene family are expressed in, and regulate the

105 The Iroquois (IRX) homeobox gene family consists of six highly conserved tr

106 lustered HOX genes, the role of nonclustered homeobox gene family members in hematopoiesis and leukem

107 nscription factor, Hoxc8, is a member of the homeobox gene family that is vital for growth and differ

108 ee was constructed to compare the sea urchin homeobox gene family to those of vertebrates, with the r

109 ressed homeobox (Hhex) gene, a member of the homeobox gene family, is an essential regulator of embry

110 of the CRX gene, itself a member of the Otx homeobox gene family.

111 The SHOX (short stature homeobox) gene family consists of two closely related me

112 We hypothesized that Dlx1, Dlx2 and Brn3b homeobox genes function in parallel intrinsic pathways t

113 The Pitx2 homeobox gene functions at the final stages of this casc

114 The Pitx2 homeobox gene functions in both cranial paraxial mesoder

115 The homeobox gene GAX inhibits angiogenesis and induces p21(

116 The homeobox gene GAX inhibits angiogenesis in vascular endo

117 The homeobox gene Gax is expressed in vascular endothelial c

118 We show here that the homeobox gene Gbx2 is essential in this process and is d

119 The mouse homeobox gene Gbx2 is first expressed throughout the pos

120 Homeobox genes Gsx1 and Gsx2 (formerly Gsh1 and Gsh2) ar

121 The homeobox gene Gsx2 (formerly Gsh2) is known to be requir

122 The homeobox gene Gsx2 has previously been shown to be requi

123 Homeobox genes have been correlated with cancer patient

124 Using transgenic mice in which the homeobox gene HB9 drives the reporter green fluorescent

125 The homeobox gene Hb9 is expressed selectively by motor neur

126 The homeobox gene Hesx1 is an essential repressor that is re

127 report we have investigated the role of the homeobox gene Hex in the development and differentiation

128 ent upon the cell-autonomous activity of the homeobox gene Hex.

129 The homeobox gene hhex is one of the earliest markers of the

130 e found that the hematopoietically expressed homeobox gene Hhex is overexpressed in acute myeloid leu

131 acts in part by inhibiting expression of the homeobox gene hhex, which is one of the earliest foregut

132 The hematopoietically expressed homeobox gene, Hhex, is a transcription factor that is i

133 nvestigated the role of the homeodomain-only homeobox gene, HOPX, in the pathogenesis of HNSCC.

134 The homeobox gene Hoxa-13 codes for a transcription factor i

135 The homeobox gene HOXA10 controls uterine organogenesis duri

136 The homeobox gene Hoxa10 controls uterine organogenesis, and

137 We found that MLL directly activates the Homeobox gene HOXA10.

138 The homeobox gene HOXA5 encodes a transcription factor that

139 ing site in the 3'-UTR of the antiangiogenic homeobox gene HOXA5, the expression and antiangiogenic a

140 The homeobox gene HOXA9 has recently been shown to be an imp

141 am in the cell of origin, which includes the homeobox genes Hoxa9 and Meis1 as key components.

142 Here, we show that the Hox homeobox gene Hoxb8a is a critical component that acts d

143 The homeobox gene HOXC6 was highly up-regulated in human gas

144 mporal expression analysis of additional LIM-homeobox genes identifies a LIM-homeobox gene network du

145 , we focus on the function of Msx1 and Msx2, homeobox genes implicated in several disorders affecting

146 ory elements and altered expression of these homeobox genes implicates CHD7 in the maintenance of cer

147 vo shRNA screen to identify a new role for a homeobox gene in human mammary adenocarcinoma.

148 ere we report a case of rapid evolution of a homeobox gene in humans and non-human primates.

149 Mutation of the Chx10 homeobox gene in mice and humans causes congenital blind

150 This study reveals a novel role for a homeobox gene in ovarian tumorigenicity by its induction

151 didates for causing FSHD, including the DUX4 homeobox gene in the D4Z4 repeat, but none have been def

152 a recently identified cluster of 12 X-linked homeobox genes in mice.

153 sed interest in understanding the role(s) of homeobox genes in regulating development of reproductive

154 ion may reflect a broader role for other LIM-homeobox genes in retinal development, and perhaps in es

155 re we describe, annotate and name four novel homeobox genes in the human genome: ARGFX, DPRX, TPRX1 a

156 lf (104 of 192) of all CpG island-associated homeobox genes in the lung cancer cell line A549 were me

157 erize the expression patterns of a set of 49 homeobox genes in the MOE with in situ hybridization.

158 sx1 are the only Paired-like CVC (Prd-L:CVC) homeobox genes in the mouse genome.

159 me that an epigenetic drug could up-regulate homeobox genes in the reproductive homeobox genes on chr

160 h consistent high-level expression of select Homeobox genes, including HOXA9.

161 Seven such loci were near homeobox genes, including the HOXC and HOXD clusters, an

162 thylation of the 5' CpG island region of the homeobox gene Irx3 in TRAMP is associated with reduced g

163 y connected, at megabase distances, with the homeobox gene IRX3.

164 TheRpx/Hesx1 homeobox gene is expressed during gastrulation in the an

165 In C. elegans, the ceh-36 Otx homeobox gene is expressed in the AWC sensory neurons th

166 ate that the Zfhx1b (Sip1, Zeb2) zinc finger homeobox gene is required in the MGE, directly downstrea

167 Genome clustering of homeobox genes is often thought to reflect arrangements

168 of DLX4, a transcription factor encoded by a homeobox gene, is associated with reduced survival of ov

169 t SHOOT MERISTEMLESS, a class I KNOTTED-LIKE HOMEOBOX gene, is likely to play a role in PLB regenerat

170 We tested the role of the LIM-homeobox gene Isl1 in the development of forebrain choli

171 The expression of LIM homeobox genes islet1 and islet2 is tightly regulated du

172 and cyclin D1 (CCND1) with the IL-6-induced homeobox gene ISX (intestine-specific homeobox) in 119 p

173 wn 129sv mouse and the visual blind cone-rod homeobox gene knock out mouse (Crx(-/-) ) with degenerat

174 The knotted-like homeobox gene knox10, which is located on the short arm

175 Here we show that the homeobox gene Lbx1 determines a GABAergic cell fate in t

176 The finding of widespread methylation of homeobox genes lends support to the hypothesis that a su

177 Here we report that two closely related LIM-homeobox genes, Lhx1 and Lhx5, were expressed in the dev

178 The LIM homeobox gene Lhx2 is expressed in cortical progenitors

179 In this study, we show that the LIM-homeobox gene Lhx2 is extensively expressed in the devel

180 Here, we provide evidence that the LIM homeobox gene Lhx2, which is expressed in the optic neur

181 Here we present evidence that the LIM-homeobox gene Lhx3, a direct target of beta-catenin, is

182 The LIM-homeobox gene Lhx6 is induced by this rescue experiment,

183 hlh2 bHLH transcription factor, but lack LIM homeobox gene Lhx8 and show reduced expression of Ngn3.

184 nhibition in orofacial tissue, and uncovered homeobox genes lhx8 and msx2.

185 We show that in one mutant strain the LIM homeobox gene lim-6 is defective whereas in another stra

186 of ASER to inhibit the expression of the LIM homeobox gene lim-6, neuropeptide-encoding genes and put

187 The LIM-class homeobox gene Lim1 is expressed in the intermediate meso

188 NKX3.1 is a homeobox gene located at chromosome 8p21.2, and one copy

189 Pitx2 is the homeobox gene located in proximity to the human 4q25 fam

190 idopsis thaliana) contains approximately 100 homeobox genes, many of which have been shown to play cr

191 licated by the top DMRs were protocadherins, homeobox genes, MAPKs and ryanodine receptors.

192 The DLX4 homeobox gene maps to the 17q21.3-q22 region that is amp

193 are characterized by high expression of the homeobox gene MEIS1.

194 n signature revealed overexpression of FLT3, homeobox genes (MEIS1, PBX3, HOXB3), and immunotherapeut

195 lators of cardiac development, including the homeobox gene MEIS2.

196 altered in Alzheimer disease, including the homeobox gene MEOX2 (also known as GAX), a regulator of

197 A principal function of Gsc and Vent1/2 homeobox genes might be to mediate a self-adjusting mech

198 bryo have pointed to a critical role for the homeobox gene Mix-like (mMix) in gastrulation, its funct

199 Here we show that the muscle segment homeobox gene (Msh) family members Msx1 and Msx2, which

200 The expression of the homeobox genes Msx1 and Msx2 is dramatically reduced in

201 licated in EMT in cancer metastases, and the homeobox genes Msx1 and Msx2.

202 The zebrafish muscle segment homeobox genes msxB, msxC and msxE are expressed in part

203 e regulated by Nanog-like and identified the homeobox gene mxtx2, which is both necessary and suffici

204 The homeobox gene Nanog is a key intrinsic determinant of se

205 ditional LIM-homeobox genes identifies a LIM-homeobox gene network during bipolar cell development th

206 The cardiac homeobox gene Nkx2.5 plays a key and dosage-sensitive ro

207 The cardiac specific homeobox gene nkx2.5, a member of the nk-2 class family,

208 of prostate epithelial differentiation, the homeobox gene Nkx3-1, marks a stem cell population that

209 Expression of the homeobox gene Nkx3.1 was lost in Tsc1-deficient mPIN, an

210 n to disrupt folliculogenesis: newborn ovary homeobox gene (Nobox) and factor in the germ-line alpha

211 entification and characterization of a novel homeobox gene of the paired-like class on the X chromoso

212 uced cells revealed up-regulation of several homeobox genes of the A and B cluster as well as of Meis

213 -regulate homeobox genes in the reproductive homeobox genes on chromosome X (Rhox) family, including

214 es the pervasive influence of gut mesenchyme homeobox genes on endoderm differentiation and digestive

215 ort the discovery of a cluster of 12 related homeobox genes on the X chromosome expressed in male and

216 Special attention was given to homeobox genes, opsin genes, genes involved in neural cr

217 edulloblastoma cell lines, we found that the homeobox gene OTX2 was amplified more than 10-fold in th

218 ebrates, the common expression border of two homeobox genes, Otx2 and Gbx2, demarcates the prospectiv

219 also affects the expression of other ventral homeobox genes, particularly Six3 and Emx2.

220 mediated TGF-beta/BMP signaling controls the homeobox gene patterning of oral/aboral and proximal/dis

221 This is similar to the effect of homeobox gene patterning of vertebrae in modern mammals,

222 egut endoderm is marked by activation of the homeobox gene Pdx1 (IPF1).

223 Two redundant functioning homeobox genes, PENNYWISE (PNY) and POUND-FOOLISH (PNF),

224 Two related BEL1-like homeobox genes, PENNYWISE (PNY) and POUND-FOOLISH (PNF),

225 Heterozygous mutations in the homeobox gene, PITX2, result in ocular anterior segment

226 of mouse mutant aphakia have implicated the homeobox gene Pitx3 in the survival of substantia nigra

227 These data suggest that beta-catenin and homeobox genes play an important and conserved role in i

228 The NKX3.1 homeobox gene plays essential roles in prostate differen

229 alyse the chromosomal organization of the NK homeobox genes, presumed to be part of a single cluster

230 ESX1 is an X-linked homeobox gene primarily expressed in the placenta and te

231 m under the control of the pancreas duodenal homeobox gene promoter.

232 mesters to determine methylation patterns of homeobox gene promoters across gestation.

233 Identification of this family of homeobox genes provides an opportunity to study colinear

234 Expression of the homeobox gene Prox1 in the exocrine pancreas changes thr

235 The homeobox gene Prox1 is crucial for mammalian lymphatic v

236 The activity of the homeobox gene Prox1 is necessary and sufficient for veno

237 ional inactivation of a single allele of the homeobox gene Prox1 led to adult-onset obesity due to ab

238 gut epithelium requires the activity of the homeobox gene Prox1.

239 The paired-related homeobox genes, Prx1 and Prx2, encode transcription fact

240 ow that the proximal promoter from the Rhox5 homeobox gene recruits polymerase II and begins elongati

241 that evolution of an enhancer element in the homeobox gene REDUCED COMPLEXITY (RCO) altered leaf shap

242 Homeobox genes regulate embryonic and placental developm

243 We show that Dlx1/Dlx2 homeobox genes regulate GABA synthesis during forebrain

244 SCL/TAL1, GATA1, GATA2, CD34, CD31, and the homeobox gene-regulating factor CDX4 These data indicate

245 ed the lineage of selected Emx2+ [vertebrate homeobox gene related to Drosophila empty spiracles (ems

246 Lastly, we provide evidence that Prx homeobox genes repress expression of an Msx2 transgene,

247 Lim 1 is a homeobox gene required for head and urogenital developme

248 ized STIMPY (STIP; also called WOX9 [12]), a homeobox gene required for the growth of the vegetative

249 Thus, the up-regulation of the 4 homeobox genes resulting from the down-regulation of miR

250 lved loss of expression of the knotted1-like homeobox gene SHOOTMERISTEMLESS (STM) in leaves and that

251 activity of the class I KNOX (KNOTTED1-like homeobox) genes SHOOTMERISTEMLESS (STM) and BREVIPEDICEL

252 rimary myoblasts from mice lacking the Barx2 homeobox gene show altered patterns of actin remodeling,

253 ontrast, expression of TCP, TPR and KNOTTED1 homeobox genes showed a sustained down-regulation.

254 The short stature homeobox gene SHOX is associated with idiopathic short s

255 Mutations in the short stature homeobox gene SHOX lead to growth retardation associated

256 The short stature homeobox gene Shox2 is an important player in the SAN ge

257 recently reported that overexpression of a 4-homeobox-gene signature (ie, PBX3/HOXA7/HOXA9/HOXA11) is

258 The independent prognostic impact of this 4-homeobox-gene signature was confirmed in a validation se

259 e report that functional inactivation of the homeobox gene Six2 results in premature and ectopic diff

260 Mutations in the homeobox gene SIX3 account for 1.3% of all cases of huma

261 The homeobox gene Six3 is expressed in ependymal cells durin

262 The homeobox gene Six3 is expressed in the developing pituit

263 The homeobox gene Six3 regulates forebrain development.

264 The homeobox gene Six3 represses Wnt1 transcription.

265 n signaling is involved in activation of the homeobox gene STIMPY (STIP or WOX9) expression in merist

266 Also, the homeobox gene, STIMPY, emerges strongly as a link betwee

267 CpG islands associated with many other homeobox genes, such as SIX, LHX, PAX, DLX, and Engraile

268 The tissue-specific expression patterns of homeobox genes suggested roles in both vegetative and re

269 ibuted greatly to the expansion of the grape homeobox gene superfamily.

270 eltamir larvae derepress a network of direct homeobox gene targets in the posterior ventral nerve cor

271 NKX3.1 is a homeobox gene that codes for a haploinsufficient prostat

272 ls of ovarian cancer that expressed HOXA9, a homeobox gene that is associated with poor prognosis in

273 ive damage and loss-of-function of Nkx3.1, a homeobox gene that is known to be required for prostatic

274 Pitx2, a paired-related homeobox gene that is mutated in Rieger syndrome I, is t

275 Gbx2 is a homeobox gene that plays a crucial role in positioning t

276 at the enhancer level of bagpipe (bap), a NK homeobox gene that serves as an early regulator of visce

277 ouse Rhox gene cluster contains more than 30 homeobox genes that are candidates to regulate multiple

278 The X-linked RHOX cluster encodes a set of homeobox genes that are selectively expressed in the rep

279 Two key Class I KNOTTED1-like homeobox genes that promote meristem identity in the cam

280 The NK homeobox gene tinman (tin) is required for the specifica

281 n specifically prevents CBs that express the homeobox gene tinman from completing their dorsal migrat

282 We previously reported that the homeobox genes Tlx1 and Tlx3 determine glutamatergic cel

283 attenuate the potential of stem cell active homeobox genes to acquire oncogenic properties.

284 age of the libraries by detecting most known homeobox gene transcription factor cDNAs.

285 The homeobox gene Tshz1 is expressed in a unique patchy patt

286 llaborating transcription factors is the POU homeobox gene unc-86, which collaborates with ttx-3 to d

287 rative functions of Bmp-activated downstream homeobox genes, ved, vent and vox.

288 n for dominant enhancers of mutations in the homeobox genes vox and vent, which function in parallel

289 Recently, eight mutations in the SIX1 homeobox gene were discovered in BOR patients.

290 Six homeobox genes were among them; ALX4, HOXC11, HOXD3, and

291 A total of 45 homeobox genes were detected as part of the pituitary tr

292 Most homeobox genes were hypo-methylated throughout gestation

293 One candidate is the Aristaless (Arx) homeobox gene, which lies genetically downstream of the

294 The human DLX homeobox genes, which are related to Dll (Drosophila dis

295 and sequence analyses of their Hox and other homeobox genes, which encode crucial transcription facto

296 racterized the genetic relationship of these homeobox genes with LFY and FT.

297 gnificant number of embryonic patterning and homeobox genes with region-specific expression in the ad

298 lium and in the milkweed bug Oncopeltus, the homeobox gene zerknullt (zen) controls the fusion of the

299 with novel expression characteristics of the homeobox gene zerknullt (zen), including a broad zen exp

300 oth genes requires the early activity of the homeobox gene zerknullt (zen).