ライフサイエンスコーパス: homeobox protein

1 raction with members of the PBC subfamily of homeobox proteins.

2 or and human diabetes gene pancreas/duodenum homeobox protein 1 (Pdx1) regulates beta-cell survival a

3 e best known of which is pancreatic duodenal homeobox protein 1 (Pdx1).

4 tudy of cardiac function in prospero-related homeobox protein 1 (Prox1) heterozygous mice, using pres

5 ic identity through upregulation of prospero homeobox protein 1 (PROX1), the master regulator of lymp

6 and the transcription factor paired-related homeobox protein 1 (PRRX1; alias PRX-1), a newly identif

7 type, expressing lymphatic markers (prospero homeobox protein 1 and vascular endothelial growth facto

8 results in attenuated expression of prospero homeobox protein 1 during development.

9 r 3 (VEGFR-3) but not of LYVE-1 and prospero homeobox protein 1.

10 ing the transcription factor T cell leukemia homeobox protein-1) has a major role in the pathogenesis

11 Caudal-related homeobox protein 2 (Cdx2) is an intestine-specific trans

12 ntaining the K50 class homeodomain Pituitary homeobox protein 2 (PITX2) bound to its consensus DNA si

13 cine zipper protein (HD-ZIP)-encoding genes: HOMEOBOX PROTEIN 21 (HB21), HOMEOBOX PROTEIN 40 (HB40),

14 -encoding genes: HOMEOBOX PROTEIN 21 (HB21), HOMEOBOX PROTEIN 40 (HB40), and HOMEOBOX PROTEIN 53 (HB5

15 N 21 (HB21), HOMEOBOX PROTEIN 40 (HB40), and HOMEOBOX PROTEIN 53 (HB53).

16 cgn), specificity protein 8 (SP8) and/or LIM homeobox protein 7 (Lhx7) separates striatal CR+ interne

17 ed null mutations of GSC, encoding Goosecoid homeobox protein, a paired-like homeodomain transcriptio

18 initiation do not express KNOX (Knotted-like homeobox) proteins, a molecular marker for shoot apical

19 t and included LIM1, POD1, GFRA1, WT1, BCL2, Homeobox protein A11, timeless, pleiotrophin, HGF, HNF3,

20 Our previous study of LPS predicted homeobox protein A5 (HOXA5) as a target of miR-26a-2, an

21 Because BELL homeobox proteins are a family of plant-specific transcr

22 Homeobox proteins are critical regulators of development

23 Three-amino acid extension loop (TALE) homeobox proteins are highly conserved transcription reg

24 Ato repression is mediated by the conserved homeobox proteins BarH1 and BarH2.

25 The homeobox protein Barx2 is expressed in both smooth and s

26 ral retina leucine zipper) and CRX (cone rod homeobox) proteins bind to the adjacent NRE and Ret-4 si

27 er," and motifs in this enhancer contain the homeobox protein-binding site TTATTAACA.

28 Expression of the homeobox protein CDX1 is lost or reduced in a significan

29 Homeobox proteins comprise a major class of transcriptio

30 Mutations in the cone-rod-homeobox protein CRX are typically associated with domin

31 rid screens with Nr2e3 as bait, the cone-rod homeobox protein Crx was identified as an interacting pa

32 st two-hybrid assays indicated that cone-rod homeobox protein (CRX) interacts with ataxin-7, we perfo

33 The cardiac muscle-restricted homeobox protein Csx/Nkx2.5 (Csx) is expressed in the pr

34 family, NKx 2.5, the cardiac muscle-specific homeobox protein (CSX).

35 Because BLR encodes a BELL1-like (BELL) homeobox protein, direct binding of BLR to AG cis-regula

36 benstein and colleagues demonstrate that the homeobox proteins Dlx1 and Dlx2 promote interneuron migr

37 n the transcriptional regulation mediated by Homeobox proteins during embryonic development and cellu

38 al subtypes express Distalless-related (DLX) homeobox proteins during their differentiation, we set o

39 the insulinoma-associated protein, IA-1, the homeobox protein Gsh-1, and the vertebrate but not the D

40 up-regulated Ape1 via a transcription factor homeobox protein Hox-A5-dependent mechanism.

41 NUP98 fused to the homeodomain region of the homeobox protein HOXA9, and acts as an aberrant transcri

42 epigenetic silencing of RASSF1A requires the homeobox protein HOXB3.

43 om overexpression of a class 1 KNOTTED1-like homeobox protein in Arabidopsis plants.

44 r findings support a key role for the HOXC10 homeobox protein in cervical cancer progression.

45 d the ability to bind with TaHOX1 (the first homeobox protein in Triticum aestivum).

46 dings suggest that these variants affect the homeobox protein IRX3.

47 suggest that the activity of KN1 and related homeobox proteins is maintained following intercellular

48 We demonstrate that Hopx, an atypical homeobox protein, is a specific marker of +4 cells.

49 Previous studies have shown that the LIM homeobox protein Islet1 (ISL1) marks the LGE subventricu

50 We report here that the intestine-specific homeobox protein ISX is critical to control the metaboli

51 e for beta-catenin-mediated expansion of LIM/homeobox protein Lhx2(+) cells, in the stem/early progen

52 tative NKE elements, possible targets of NK2 homeobox proteins like the essential islet transcription

53 Here we show that homeobox protein Mohawk (Mkx) is a key transcription fac

54 lly cloned cog-1 and found that it encodes a homeobox protein most similar to the mammalian GTX and N

55 protein interaction network surrounding the homeobox protein Nanog.

56 diac MLCK is highly regulated by the cardiac homeobox protein Nkx2-5 in neonatal cardiomyocytes.

57 Decreased levels of the prostate-specific homeobox protein NKX3.1 are correlated with hormone-refr

58 The prostatic homeobox protein Nkx3.1, a known proliferation inhibitor

59 n the nucleus and with an androgen-regulated homeobox protein (NKX3.1) in the cytoplasm of LNCaP cell

60 n vertebrate embryogenesis identified Xom, a homeobox protein of the bone morphogenetic protein 4 pat

61 we identify a pathway in which the conserved homeobox protein Orthodenticle (Otd) acts together with

62 gulation of the expression boundaries of the homeobox proteins Pax6, Dbx2 and Msx1 generates precurso

63 n of five of these proteins as the dispersed homeobox protein PDX-1.

64 Like certain other homeobox proteins, PDX-1 contains a consensus FPWMK moti

65 leading to organ asymmetry - implicating the homeobox protein Pitz-2 in one key step - and others sup

66 The clustered homeobox proteins play crucial roles in development, hem

67 In vertebrates, PBC and MEIS homeobox proteins play important roles in development an

68 ype specific, with transcription factors and homeobox proteins predominating in embryonal cells and g

69 granule cells, coexpressed calbindin and the homeobox protein Prox1.

70 a previously identified gene that encodes a homeobox protein required for normal trichome and root h

71 nes encoding the DM protein kinase (DMPK), a homeobox protein Six5 and a protein containing WD repeat

72 The homeobox protein STF-1 appears to function as a master c

73 ed localization of Not mRNA, which encodes a homeobox protein that distinguishes mesoderm from endode

74 CDX1 is a homeobox protein that inhibits proliferation of intestin

75 , designated GPBOX, encodes a 227-amino-acid homeobox protein that is first expressed at E10.5 in the

76 ions and responses; and (c) HLX1, encoding a homeobox protein that may regulate T-cell development.

77 ; the cold shock protein, CspC; the YbgS (or homeobox protein); the putative stress-response protein

78 ain are the response elements for the NKx2.1 homeobox protein, thyroid transcription factor 1 (TTF1).

79 s that are distinct from, but interact with, homeobox proteins to establish lineage-specific gene exp

80 ) fusions of KN1 and Arabidopsis KN1-related homeobox proteins to that of the viral movement protein

81 LeHB-1, a previously uncharacterized tomato homeobox protein, was shown by gel retardation assay to

82 tina-specific transcription factor, cone-rod homeobox protein, which binds to a pineal regulatory ele

83 investigate the mechanism by which the Six1 homeobox protein, which has a crucial role during develo

84 valuated by immunohistochemistry for CDX2, a homeobox protein whose expression in normal adult tissue

85 opment and function, including LIM proteins, homeobox proteins, wnt and T-box pathway proteins, as we

86 regulated targets, zinc finger E-box binding homeobox proteins ZEB1 and ZEB2, which act as transcript

87 -regulation of the zinc finger E-box binding homeobox protein, ZEB2, and the down-regulation of miR-2