ライフサイエンスコーパス: homeostasis

1 nvasion and anoikis resistance through redox homeostasis.

2 s producing glucagon and insulin for glucose homeostasis.

3 tion of starch breakdown to maintain sucrose homeostasis.

4 ted by associative plasticity or by synaptic homeostasis.

5 es, for the modulation of distinct facets of homeostasis.

6 eductase (TrxR) system maintains thiol redox homeostasis.

7 e the hepatic acute-phase response and lipid homeostasis.

8 ective prevention and control of the insulin homeostasis.

9 rols the tissue microenvironment and barrier homeostasis.

10 pact on both normal and pathological DAergic homeostasis.

11 way may link outer membrane fusion to lipids homeostasis.

12 r of regulation in maintaining cellular iron homeostasis.

13 red disturbances in peripheral B- and T-cell homeostasis.

14 glucose detection and the control of energy homeostasis.

15 /miR-155-dependent Treg cell development and homeostasis.

16 model for membrane transport, signaling, and homeostasis.

17 ism plays in seed development and amino acid homeostasis.

18 nd characterized by altered glycogen/glucose homeostasis.

19 age and have important functions in skeletal homeostasis.

20 ions critical for the maintenance of mucosal homeostasis.

21 dulators and acts as a major driver of sleep homeostasis.

22 d balance, and (4) cholesterol synthesis and homeostasis.

23 by differential actions on lipid and glucose homeostasis.

24 me levels, white blood cell counts, and iron homeostasis.

25 s in glomerular cells during development and homeostasis.

26 lays important roles in maintaining cellular homeostasis.

27 cells impaired insulin secretion and glucose homeostasis.

28 rms dual functions to maintain mitochondrial homeostasis.

29 unctions to maintain normal bodily acid-base homeostasis.

30 bon and amino acid metabolisms to biofilm pH homeostasis.

31 and beta-cells in order to maintain glucose homeostasis.

32 pitulated the order of maturation in healthy homeostasis.

33 luences their activation, proliferation, and homeostasis.

34 avorable consequences for whole-body glucose homeostasis.

35 , may play a role fundamental role in immune homeostasis.

36 t their dietary strategy to maintain protein homeostasis.

37 aging requires autophagy to regulate protein homeostasis.

38 perilacunar bone matrix to maintain mineral homeostasis.

39 central role of Fli1 in regulating vascular homeostasis.

40 to adjust iBAT activity and maintain energy homeostasis.

41 e unfolded protein response (UPR) to restore homeostasis.

42 tween intracellular Ca(2+) levels and energy homeostasis.

43 ge are critical parts of achieving metabolic homeostasis.

44 ing that results in dysregulation of glucose homeostasis.

45 ntaining receptor in the context of platelet homeostasis.

46 e responses to infection and maintain tissue homeostasis.

47 one receptor that controls lipid and glucose homeostasis.

48 gnaling pathways involved in regulating skin homeostasis.

49 ient mice did not have defects in intestinal homeostasis.

50 sents a critical component in healthy energy homeostasis.

51 positively regulate neutrophil survival and homeostasis.

52 n, lung epithelial cell identity, and tissue homeostasis.

53 NK in the control of feeding and body weight homeostasis.

54 has helped explain how AMPK restores energy homeostasis.

55 ted expression of Il1b, and supported tissue homeostasis.

56 r the maintenance of cellular and organismal homeostasis.

57 lood pressure (BP), acid-base, and potassium homeostasis.

58 itical incretin that regulates blood glucose homeostasis.

59 dinate cellular stress responses with sterol homeostasis.

60 osteoclasts is required for bone health and homeostasis.

61 logical roles in insulin release and glucose homeostasis.

62 (COX) assembly and the regulation of copper homeostasis.

63 e) and are extensively involved in acid-base homeostasis.

64 m is essential for insulin-regulated glucose homeostasis.

65 involved in development, growth, repair and homeostasis.

66 ay in developmental plasticity and metabolic homeostasis.

67 ct expression of genes involved in phosphate homeostasis.

68 mportant target of insulin action on glucose homeostasis.

69 on of mutant cells to maintain proper tissue homeostasis.

70 lerosis, macromolecule production, and redox homeostasis.

71 etabolic pathways to warrant systemic energy homeostasis.

72 le in regulating food consumption and energy homeostasis.

73 atocytes did not show any changes in glucose homeostasis.

74 hanical loads in order to maintain cartilage homeostasis.

75 ive process that functions to restore tissue homeostasis.

76 tonomic responses to maintain cardiovascular homeostasis, a basic understanding of the regulation and

77 show that it does not achieve global perfect homeostasis-a condition where internal nutrient concentr

78 sourea-mutagenized grandsires for intestinal homeostasis abnormalities after oral administration of d

79 ignals to control cell growth and organismal homeostasis across eukaryotes.

80 sleep may play a role in correcting cellular homeostasis after various insults.

81 linked sleep duration and quality to glucose homeostasis, although the mechanistic pathways remain un

82 phagy, resulting in changes of mitochondrial homeostasis and alterations in GC and antibody-secreting

83 Ps), atrial NP and B-type NP, regulate fluid homeostasis and arterial BP through renal actions involv

84 gs indicate a major role for TRPV4 in Ca(2+) homeostasis and barrier function in human retinal capill

85 tudies identify a complex regulation of 5-HT homeostasis and behaviors by integrin alphavbeta3, revea

86 We examined glucose homeostasis and beta-cell function of these mice fed a c

87 lysine kinase 4 (WNK4) regulates electrolyte homeostasis and blood pressure.

88 implies that developmental changes in sleep homeostasis and circadian amplitude make adolescents par

89 Sleep homeostasis and circadian function are important maintai

90 sults in dysregulation of lung microvascular homeostasis and contributes to lung pathology in ARDS.

91 rgy-dense diet is known to disrupt metabolic homeostasis and contributes to the disease risk, circadi

92 outlines how a core concept from theories of homeostasis and cybernetics, the inference-control loop,

93 ls is important for maintaining interstitial homeostasis and delivering antigens and soluble factors

94 n-specific manner to maintain cardiac energy homeostasis and determines cardiac physiological adaptat

95 Connexins play essential roles in lens homeostasis and development.

96 f regulatory genes involved in cardiomyocyte homeostasis and disease compensation.

97 amily signaling to normal development, adult homeostasis and disease, and also revealed novel mechani

98 et mRNAs, and play key roles in development, homeostasis and disease.

99 plays multiple roles in development, tissue homeostasis and disease.

100 lay key roles in development and periodontal homeostasis and during the loss of periodontal tissue in

101 is required for maintaining cellular Ca(2+) homeostasis and electrical stability in murine atria und

102 also BK channel function in maintaining ASL homeostasis and emphasize the possibility that pirfenido

103 on shapes the myeloid cell repertoire during homeostasis and following infection.

104 ceral sensations, plays an important role in homeostasis and guiding motivated behaviour.

105 as an important central regulator in energy homeostasis and immunity.

106 progenitors (MDPs) produce monocytes during homeostasis and in response to increased demand during i

107 aracrine mechanism that coordinates neuronal homeostasis and inflammation in the CNS.

108 microcirculation is critical for endothelial homeostasis and inflammation.

109 an important role in controlling OB-ISCs in homeostasis and injury repair, which is likely to be cru

110 Microglia are essential for CNS homeostasis and innate neuroimmune function, and play im

111 hanisms that underlie the regulation of iron homeostasis and its disorders.

112 posed of genes involved in periplasmic Cu(+) homeostasis and its putative DNA recognition sequence.

113 s for BMP signaling in linking mitochondrial homeostasis and lipid metabolism.High-throughput genetic

114 Energy homeostasis and oncogenic signaling are critical determi

115 role of cell death in maintenance of T-cell homeostasis and outline novel therapeutic strategies tai

116 fferential actions of ILP7 and ILP8 in lipid homeostasis and ovarian development.

117 ications in understanding its impact on skin homeostasis and pathogenesis.

118 5), a key regulator of endoplasmic reticulum homeostasis and PI3K/AKT signaling, is overexpressed in

119 at FDXR was necessary for mitochondrial iron homeostasis and proper expression of several master regu

120 GF receptor signaling to regulate intestinal homeostasis and regeneration, as well as adenoma formati

121 nd our experiments highlight concerns on the homeostasis and regenerative capacity of muscles in thes

122 ls produced in adult organisms during tissue homeostasis and repair.

123 , failed to activate AMPK and sustain energy homeostasis and resulted in apoptosis.

124 Proper bone homeostasis and skeletal strength are maintained by bala

125 uiescence" plays an important role in tissue homeostasis and stem cell biology.

126 Rdelta is important in maintaining metabolic homeostasis and suggest that intestinal-specific activat

127 describe a role for talin in maintaining the homeostasis and survival of the regulatory T (Treg) cell

128 ophagy is essential for maintaining cellular homeostasis and survival under various stress conditions

129 ds including cholesterol to support neuronal homeostasis and synaptic integrity.

130 ssary for normal TMJ condyle development and homeostasis and that these DDR2 functions are restricted

131 rol of genetic programs involved in cellular homeostasis and the associated diseases.

132 importance of vasodilation in cardiovascular homeostasis and therapy, our structural understanding of

133 ling in AT2 cells, contributing to both lung homeostasis and tumor initiation.

134 x-1 expression may play a key role in tissue homeostasis and wound healing during Th2-mediated immune

135 they reside, and how they function in normal homeostasis and wound repair.

136 hondrial membrane potential controls calcium homeostasis, and AMP-activated protein kinase (AMPK) is

137 acellular proteolysis is crucial for protein homeostasis, and ClpP proteases are conserved between eu

138 ochrome bc1 complex, disruption of cell-wall homeostasis, and DNA damage.

139 New insight into the development, homeostasis, and functions of distinct IEL subsets has r

140 ypes of cells important to iron acquisition, homeostasis, and hematopoiesis (enterocytes, hepatocytes

141 ant mechanism of how p97 maintains lysosomal homeostasis, and implicate the pathway as a modulator of

142 stem is best known for its control of B cell homeostasis, and it is a target of therapeutic intervent

143 Oylation is critical in maintaining cellular homeostasis, and its deregulation leads to the corruptio

144 ia play critical roles in brain development, homeostasis, and neurological disorders.

145 and thereby pivotally modulates development, homeostasis, and plasticity.

146 cts to dampen thermogenesis, maintain tissue homeostasis, and reveal an electrophysiological regulato

147 te that hENT3 is indispensable for lysosomal homeostasis, and that mutations in hENT3 can result in a

148 ON1-RELATED KINASE1 involved in sugar/energy homeostasis, and the posttranslational regulation of WRI

149 uding autophagosome degradation, cholesterol homeostasis, antigen presentation, and cell invasion.

150 lp cells in attenuating dentin resorption in homeostasis are also reviewed.

151 ynaptic strength, short-term plasticity, and homeostasis are determined input-specifically, generatin

152 We discuss ribosome homeostasis as an overarching principle that governs the

153 ists regulate metabolic hormones and glucose homeostasis as efficiently as human ligands, although fu

154 oliferating cells require to maintain energy homeostasis as well as to build plasma membranes for new

155 it can nonetheless disrupt intestinal immune homeostasis at inductive and effector sites of oral tole

156 lation in the regulation of cellular protein homeostasis beyond the endoplasmic reticulum.

157 carbon [BC] and PM2.5 levels, serum calcium homeostasis biomarkers (parathyroid hormone, calcium, an

158 rols helminth infection and maintains tissue homeostasis but can lead to allergy and fibrosis if not

159 ycling system that is essential for cellular homeostasis but is dysregulated in a number of diseases,

160 abundant in the liver and involved in lipid homeostasis, but its relevance to the long-term risk of

161 ppreciated mechanism for restoring stem cell homeostasis, but one with some associated risk in animal

162 apparent role in early bone development and homeostasis, but which is required for osteoclast-mediat

163 work, we study the effects produced on iron homeostasis by a wide range of copper concentrations in

164 haperones play key roles in cellular protein homeostasis by binding to exposed hydrophobic regions of

165 Regulation of glucose homeostasis by insulin depends on beta-cell growth and f

166 Under steady-state conditions, MG maintain homeostasis by producing antiinflammatory cytokines and

167 ly isolated microdomains, facilitating local homeostasis by redistributing ions, removing neurotransm

168 line transporter gene, CTL1, controls ionome homeostasis by regulating the secretory trafficking of p

169 process is a significant decline in adaptive homeostasis capacity.

170 ved better than Apelin-13 by improving fluid homeostasis, cardiovascular hemodynamics recovery, and l

171 potassium pump that maintains intracellular homeostasis, cell shape and turgor under conditions in w

172 erized neuron types in maintaining metabolic homeostasis, communication between these cells remains p

173 Defects in stress granule homeostasis constitute a cornerstone of ALS/FTLD pathoge

174 l description of airway surface liquid (ASL) homeostasis could accelerate development of such therapi

175 Disturbances in endoplasmic reticulum (ER) homeostasis create a condition termed ER stress.

176 verging roles in the regulation of metabolic homeostasis depending on the energetic state.

177 Cellular protein homeostasis depends on heat shock proteins 70 kDa (Hsp70

178 C as a novel regulator of energy and glucose homeostasis downstream of the leptin-PI3K pathway in POM

179 to early embryonic development and cellular homeostasis during adulthood.

180 are links between the two and that synaptic homeostasis during aging requires autophagy to regulate

181 s provide a mechanism of NCoR1 in intestinal homeostasis during development and provide a key link to

182 n the concept that cytokinin regulates auxin homeostasis during gynoecium development.

183 into a critical mechanism in satellite cell homeostasis during muscle regeneration could help inform

184 Adaptive homeostasis enables biological systems to make continuou

185 ATEMENT Evolutionary pressure driving energy homeostasis favored detection and comparison of caloric

186 Here, we demonstrate that during homeostasis, FRCs also suppress T cell activation via pr

187 absence in secondary lymphoid tissues during homeostasis, gammadeltaT17 cells emerge in bone marrow c

188 peptide hormones involved in control of bone homeostasis, glucose regulation, satiety, and gastro-int

189 ts role in the regulation of astrocyte water homeostasis have been studied.

190 their own intrinsic requirements for copper homeostasis, have evolved mechanisms to acquire copper t

191 ical role in cellular energetics and calcium homeostasis; however, how MAM is affected under diabetic

192 The host immune response is critical for homeostasis; however, when chronic low level activation

193 atic system plays a key role in tissue fluid homeostasis, immune cell trafficking, and fat absorption

194 d complex network essential for tissue fluid homeostasis, immune trafficking and absorption of dietar

195 lipids onto CD1d, regulates liver iNKT cell homeostasis in a manner dependent on hepatocyte CD1d.

196 ever the cells are able to compensate Ca(2+) homeostasis in an efficient way to minimize systolic dys

197 ently maintaining hydrogen peroxide (H2 O2 ) homeostasis in Arabidopsis.

198 ates both LD size and cellular neutral lipid homeostasis in both leaves and seeds.

199 function of CaCC-mediated cytoplasmic Cl(-) homeostasis in controlling the organization of PtdIns(4,

200 C-1alpha in the maintenance of mitochondrial homeostasis in dopaminergic neurons.

201 hate (NADPH) production and imbalanced redox homeostasis in erythrocytes.

202 inase (AMPK) is a master regulator of energy homeostasis in eukaryotes.

203 -gated Ca(2+) channels, CaV, regulate Ca(2+) homeostasis in excitable cells following plasma membrane

204 irculating AKH levels in turn regulate lipid homeostasis in fat body/adipose and the intestine.

205 importance of oxygen, energetics, and redox homeostasis in immune cell metabolism, and how these fac

206 processes involved in modulating carotenoid homeostasis in plant tissues.

207 deling of root architecture by modulating Fe homeostasis in roots.

208 tem cells (HSCs) progressively impairs their homeostasis in the bone marrow through an unidentified m

209 plays a key role in the regulation of water homeostasis in the brain.

210 Commensal bacteria contribute to immune homeostasis in the gastrointestinal tract; however, the

211 Finally, novel therapies that might restore homeostasis in the GI tract during GVHD are highlighted.

212 endocannabinoid system in maintaining immune homeostasis in the gut/pancreas and reveals a conversati

213 position in controlling ion balance and ion homeostasis in the plant cell.

214 We sought to investigate protein homeostasis in this disease.

215 ecently, we showed an altered ocular surface homeostasis in unmanipulated NK1R(-/-) mice, suggesting

216 vel role for Erk5 during bone maturation and homeostasis in vivo.

217 5 exhibit severe dysregulation of sleep-wake homeostasis, including lack of recovery sleep and impair

218 K could potentially maintain cellular energy homeostasis independently of Thr172 phosphorylation.AMPK

219 ntrol db/db mice were phenotyped for glucose homeostasis, insulin sensitivity, insulin secretion, ste

220 Perturbation of iron homeostasis is a major strategy in host-pathogen interac

221 Gut homeostasis is a tightly regulated process requiring fin

222 -reaching implications for understanding how homeostasis is achieved in regenerating epithelia.

223 Maintenance of glucose homeostasis is achieved via functional interactions amon

224 g choice, infants' capacity to regulate iron homeostasis is important but less well understood than t

225 The energy cost of ionic homeostasis is maintained across the two models.

226 This observed neuronal homeostasis is maintained by new neurons formed in vivo

227 tly stimulated and dynamic environment where homeostasis is often disrupted, resulting in the common

228 e selectively eliminated to maintain protein homeostasis is poorly understood.

229 sed by the mucosal immune system to maintain homeostasis is the secretion of immunoglobulins (Igs) ac

230 ional roles in animal development and tissue homeostasis is unknown.

231 immunoreceptor (DCIR), a key component in DC homeostasis, is required to modulate lung inflammation a

232 ned by a more complex regulation at cellular homeostasis level.

233 Secondary effects on protein folding homeostasis likely contribute to UPR activation, but del

234 Robustness of function through homeostasis may be ensured in any system through mechani

235 rstanding and knowledge gaps related to iron homeostasis, measurement of and evidence for iron status

236 nvolving carbohydrate metabolism and glucose homeostasis mediated by GLD4.

237 The postprandial homeostasis model assessment index (+54%) and glucose co

238 ein intake and offspring fasting insulin and homeostasis model assessment of insulin resistance (HOMA

239 insulin C-peptide, glycated hemoglobin, and homeostasis model assessment of insulin resistance.

240 group of patients who lost weight, glycemia, homeostasis model of assessment of insulin resistance, s

241 t cell proteins potentially relevant to skin homeostasis: neural cell adhesion molecule L1 and dipept

242 neither interferes with prostate epithelial homeostasis nor significantly accelerates tumor initiati

243 C2C failed to rescue two defects in PM lipid homeostasis observed in E-Syts KO cells, delayed diacylg

244 gest that pathological changes in renal iron homeostasis occurs in lupus nephritis, contributing to t

245 , involved in both embryonic development and homeostasis of adult organs.

246 Furthermore, VISTA regulates the peripheral homeostasis of CD27(-) gammadelta T cells and their acti

247 opose that physiological hypoxia coordinates homeostasis of CPCs, providing mechanistic explanations

248 hat the glycogen shunt functions to maintain homeostasis of glycolytic intermediates and ATP during l

249 Notch ligands, specifically jagged-2, to the homeostasis of HSPCs is unknown.

250 ggests that glycylation is essential for the homeostasis of primary cilia, which has important implic

251 photorespiration, synthesis of hormones, and homeostasis of reactive oxygen species (ROS).

252 Symbiotic bacteria assist in maintaining homeostasis of the animal immune system.

253 We propose that the homeostasis of the non-AUG translatome is maintained thr

254 , we explored the impacts of impaired Ca(2+) homeostasis on myofibril integrity.

255 To maintain energy homeostasis, orexigenic (appetite-inducing) and anorexig

256 tal for all organisms, yet disruption of its homeostasis, particularly in labile forms that can contr

257 to the Mas receptor (MasR) improves glucose homeostasis, partly by enhancing glucose-stimulated insu

258 regulator of autophagy, a critical catabolic homeostasis pathway that involves sequestration of selec

259 ctive mathematical model of an expanded iron homeostasis pathway was constructed that includes specie

260 A element is a critical part of the low zinc homeostasis pathway.

261 Hence, connections from phosphate homeostasis (PHO) to TORC1 may differ between C. albican

262 Control of glucose homeostasis plays a critical role in health and lifespan

263 g kidney that in adult kidney contributes to homeostasis, predominantly of the collecting duct, and r

264 In homeostasis, proliferation of all epithelial and mesench

265 with a model in which PhoPQ-dependent Mg(2+) homeostasis protects Salmonella against nitrooxidative s

266 een the host and pathogen that lead to metal homeostasis provide several opportunities for intercepti

267 res specific for myeloid cell chemotaxis and homeostasis reappeared in BRAFi-resistant tumors.

268 dicating a crucial role for Blimp1 in T cell homeostasis regulation.

269 the mechanisms responsible for such adaptive homeostasis remain largely unknown.

270 skeletal muscle to maintain systemic glucose homeostasis remains largely unexplored.

271 ll function of SIRT5 in organismal metabolic homeostasis remains unclear.

272 this pathway for mitochondrial and cellular homeostasis represents a significant knowledge gap.

273 mice exhibited paradoxical superior glucose homeostasis resulting from an enhanced insulin secretion

274 sis Pathway (HBP), as well as cellular redox homeostasis, resulting in global changes in protein glyc

275 iverse mechanisms for maintaining inhibitory homeostasis.SIGNIFICANCE STATEMENT Corelease of neurotra

276 These favorable effects on metabolic homeostasis suggest that the RGD integrin-binding domain

277 e proteins enable gap junction formation and homeostasis, supporting communication between adjacent c

278 tightly regulated by the cell, maintaining a homeostasis that, if disrupted, can impair cell function

279 During animal development and homeostasis, the structure of tissues, including muscles

280 l across the cell membrane and disrupt redox homeostasis, thereby inhibiting bacterial growth.

281 ons in lipid metabolism may affect iNKT cell homeostasis through effects on CD1d-associated lipid ant

282 intestinal lamina propria contribute to gut homeostasis through the immunomodulatory interleukin IL1

283 eg cell development and peripheral Treg cell homeostasis through the regulation of BIC/microRNA 155 (

284 Cdx1 and Cdx2 also regulate intestinal homeostasis throughout life.

285 of SLC13A5 from facilitating hepatic energy homeostasis to influencing hepatoma cell proliferation a

286 These findings link immune homeostasis to key determinants of anti-tumoral immunity

287 ts of light, circadian rhythmicity and sleep homeostasis to provide a quantitative theoretical framew

288 role of SP-NK1R signaling in ocular surface homeostasis under steady-state.

289 nd TFs that dynamically cooperate to restore homeostasis upon fasting.

290 tions were inversely associated with glucose homeostasis variables and inflammation variables (all P

291 h which beige fat controls whole-body energy homeostasis via Ca(2+) cycling.

292 bacteria, fungi, and viruses mediate mucosal homeostasis via their composite genes (metagenome) and m

293 ion and the consequent deregulation of lipid homeostasis was also shown to attenuate hepatocellular c

294 s lipids and is linked to systemic metabolic homeostasis, we hypothesized that there might be thermog

295 f genes involved in the regulation of energy homeostasis were found to relate to fetal growth and neo

296 the adverse effects of ATB2 cells on glucose homeostasis were partially dependent upon T cells and ma

297 ncy, maintenance of genome integrity and ATP homeostasis were robustly expressed.

298 glia play diverse, critical roles in retinal homeostasis, which are presumably enabled by their compl

299 ong tendency to maintain physiological NADPH homeostasis, which is regulated by glucose-6-phosphate d

300 adian clocks play an important role in lipid homeostasis, with impact on various metabolic diseases.