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1 at governs thymic EC differentiation for HPC homing.
2 iched olfactory environment that facilitates homing.
3 as hematopoietic stem cell mobilization and homing.
4 into the role of Pak2 in HSPC migration and homing.
5 h possible impacts on foraging efficiency or homing.
6 l EC population with features that guide HPC homing.
7 gulator of AML cell adhesion and bone marrow homing.
8 r a4beta7 on lymphocytes controls lymphocyte homing.
9 R) directly controls thymic ECs to guide HPC homing.
10 ck circuit, a key amplifier of DC lymph node homing.
11 he intestine, further mediating gut-specific homing.
12 T cells permitted detection of intratumoral homing.
13 l candidate ChR have been implicated in skin homing.
14 proved porphyrin pharmacokinetics and tumour-homing.
15 G-CSF administration diminished cancer cell homing.
16 senchymal stromal cells (MSC) in cancer cell homing.
18 elated with increased quiescence and reduced homing abilities of Ptk7-deficient hematopoietic stem an
19 ing displaced to distant sites have impaired homing ability but it is unknown what the role of olfact
20 sor stage that leads to alterations in their homing, accumulation, and function that may be responsib
21 structures have a negative impact on disease-homing activity, highlighting the importance of glycosyl
23 autoantibody responses by increasing the gut-homing alpha4beta7 integrin expression on Tfh cells.
25 ere enriched in ontologies related to B-cell homing and activation; (2) the immune coexpression netwo
26 ne that promotes endothelial progenitor cell homing and angiogenesis, from a citrate-based antioxidan
27 st time, that mechanical signals enhance the homing and attachment of bone marrow cells to bone surfa
28 ruption of retinoid homeostasis affected gut-homing and differentiation of lymphocytes and displayed
29 g may be an effective strategy to improve BM homing and engraftment after allogeneic UCB transplantat
30 ogress, a complete understanding of how HSPC homing and engraftment are regulated is still elusive.
31 have shown that MEIS1 promotes leukemic cell homing and engraftment in bone marrow and enhances cell-
32 e a tractable human niche model for studying homing and engraftment of human hematopoietic cells in n
33 es leukemogenesis and supports leukemic cell homing and engraftment, facilitating interactions betwee
36 dings describe a novel mechanism for BMD-EPC homing and indicate that dual E-selectin/ligand pairs ma
38 our results suggest that SOX11 promotes MCL homing and invasion and increases CAM-DR through the dir
39 molecular effects of pFUS increased both MSC homing and MSC production of VEGF and IL-10, suggesting
41 ors, linTT1-functionalized NWs showed robust homing and penetration into malignant lesions, whereas o
42 NMR measurements showed greater CAR T cell homing and persistence in the tumors and spleen compared
43 lium interactions by which to facilitate EPC homing and promote neovascularization and tissue repair.
44 n (CLA(+) ) T cells are specialized for skin homing and represent the main T-cell population in atopi
47 hematopoietic stem cell regulation mediating homing and retention to the niche in the bone marrow.
48 is accompanied by Th2/Tc2 activation in skin-homing and systemic subsets, correlating with disease se
50 r findings suggest that IL10 inhibits BM-FPC homing and transdifferentiation to myofibroblasts in pre
51 tive of antigen-driven proliferation, tissue homing, and cytotoxic effector functions, with the HLA-D
54 reg cell biology, including their stability, homing, and functional specialization; integrating these
55 omoted SDF-1-CXCR4-axis-mediated chemotaxis, homing, and long-term engraftment when these cells were
58 tification Using Next-Generation Sequencing (HOMINGS) approach was used to analyze the microbiomes of
59 d their expression of several candidate skin-homing-associated chemokine receptors was measured using
60 combinational DNA repair, the probability of homing-associated loss of the effector, the fitness cost
64 ther, we report that Drosophila AMPs display homing behavior to muscle niche and that the niche-drive
65 practices and T-cell maturation, intestinal homing (beta7hi), activation, and HIV-1 coreceptor (CCR5
67 ying increased cytotoxic markers and altered homing capabilities, and remaining relatively stable ove
68 nd conventional B2 cells showed differential homing capacities with peritoneal B1 cells preferentiall
72 ma (CTCL), an often-fatal malignancy of skin-homing CD4(+) T cells for which there are few effective
73 T-cell subsets with distinct functional and homing characteristics exist, but the signaling pathways
74 D8(+) T cells caused by knockout of the skin-homing chemokine receptor CCR10 resulted in an altered b
75 derived clones expressed high levels of skin-homing chemokine receptors and migrated in the presence
76 ed an age-related shift in the expression of homing chemokines and structural deterioration of the st
80 usceptibility to HIV-1 infection (CCR5+, gut-homing, CM CD4+ T cells) was preferentially expressed in
82 enotype and expressed markers of endothelial homing (CX3CR1) and cytotoxicity (NKG2D and perforin).
84 fic for CD19 controlled the activity, tissue-homing, cytokine release, and phenotype of sCAR-T cells
85 f overwhelming antigenic stimulus and tissue homing/cytotoxic-effector functions but that a vast majo
86 nal PET imaging and quantification of T-cell homing during inflammation and cardiomyocyte viability a
88 TOR deficiency reduces the generation of gut-homing effector T-cells in both mesenteric lymph nodes a
89 effects of MSC therapy by overcoming the low homing efficiency of MSCs systemically administered in i
92 e-tolerant cleavage properties of the I-TevI homing endonuclease can be harnessed to enhance Cas9 app
93 ected evolution experiments with the GIY-YIG homing endonuclease I-TevI that targets the thymidylate
94 extensively retargeted variants of a single homing endonuclease, that have been shown to function ef
98 ge preferences, and provide insight into how homing endonucleases may escape a dead-end life cycle in
101 cues caused the animals to make directional homing errors and that the magnitude and direction of th
103 following IUHCT; and (3) enhanced donor HSC homing following firategrast treatment translates into i
105 Unlike monocytes or dendritic cells, gut-homing gammadelta T-APCs employed an IL-6 independent me
107 ient parasites are rapidly eliminated by the homing Gr1(+) inflammatory monocytes, thus highlighting
109 te immune response that engages resident and homing immune cells along with pro- and counter-inflamma
111 iming, whereas allogeneic T-cell numbers and homing in lymphoid and GVHD target organs were not consi
112 sue of Immunity, Tinoco et al. (2016) report homing-independent functions of PSGL-1 in immune checkpo
113 ls only when they were exposed to a zoospore homing inducer (5% (v/v) ethanol), which caused the tact
114 ntigen presentation in the mLNs imprints gut-homing integrin signatures on donor T cells, leading to
119 Efficient hematopoietic stem cell (HSC) homing is important for hematopoietic cell transplantati
120 viously reported that SDF-1alpha-induced EPC homing is mediated by a panel of adhesion molecules high
124 k 6, whereas cells expressing the intestinal homing marker increased steadily in the central memory (
126 Microbe, Abed et al. (2016) describe a novel homing mechanism by which fusobacteria localize to tumor
127 nstream migration and retrieval during adult homing migration of chum salmon might be controlled by e
132 t prevented downregulation of lymphoid organ homing molecules, and impeded Treg cell homing to non-ly
133 Our results may be explained by an enhanced homing motivation and possibly an enriched olfactory env
139 olecules enhance migration, polarization and homing of B cells to splenic and extranodal tissues, eve
141 d rapidly induces CXCL9 and -10 that support homing of blood-borne CXCR3-expressing NK cells to the l
142 that IL10 inhibits pressure overload-induced homing of BM-FPCs to the heart and their transdifferenti
149 d follicular stromal cells and modulates the homing of CXCR5-expressing cells toward the FDC-containi
150 tal liver (FL) and result in preferential FL homing of donor HSCs and enhanced long-term engraftment
151 HSCs from the FL and results in increased FL homing of donor HSCs following IUHCT; and (3) enhanced d
154 ermination of lesion growth, cyst formation, homing of GFP(+)/Tie2(+) EPCs, numbers of circulating EP
157 eading to defects in adhesion, migration and homing of HSCs regenerated in a Wnt5a-haploinsufficient
160 biological processes including development, homing of immune cells, wound healing, and cancer cell i
161 pregulates local chemoattractants to enhance homing of intravenously (IV)-infused MSC and improve out
162 sures to skeletal muscle would improve local homing of iv-infused MSCs and their therapeutic efficacy
163 recovery seen in patients and that boosting homing of MDMs with an anti-inflammatory bias to the inj
165 ion of Pak2-WT but not by Pak2-KD; defective homing of Pak2-deleted HSPCs was rescued by constitutive
166 establish that RAGE-PR3 interaction mediates homing of prostate cancer cells to the bone marrow.
167 ere able to follow and quantify the specific homing of systemically applied (64)Cu-labeled chicken ov
169 ssue and angiogenesis, which facilitates the homing of targeted NPs to adipose angiogenic vessels, th
170 Tfh and B cells, which is essential for the homing of Tfh cells and the development of B cell follic
177 nced myeloid differentiation and improved BM homing of UCB CD34(+) cells, an effect that was overcome
178 mokine receptors if possible to increase the homing of vaccine-primed cells to sites of infection.
180 nanosystem consisting of a tumor vasculature-homing peptide (CGKRK) fused to a pro-apoptotic peptide
181 ) conjugated with T7 peptide (T7) and stroke homing peptide (SHp) for penetrating BBB and targeting i
183 with an extended C-terminus comprised of CAR homing peptide that recognizes inflamed blood vessels an
184 umors yield a distinct landscape of vascular homing peptides characterized by over-representation of
185 uctural peptides, cell-penetrating and tumor-homing peptides, antimicrobial peptides, peptide hormone
188 focused-ultrasound (pFUS) increases enhanced homing permeability and retention of MSC in mouse kidney
189 and warrant strict safety monitoring of gut-homing perturbing agents used in treating intestinal inf
191 all-trans retinoic acid (ATRA) induces a gut-homing phenotype in activated CD4(+) conventional T cell
192 Retinoic acid, a known inducer of the gut-homing phenotype, abrogated the activation-induced demet
196 d to a cell-intrinsic increase in neutrophil-homing potential or a decrease in protection against L.
197 or, CD44, on MSC membranes, to improve their homing potential towards an inflammatory site without af
198 ine production, gene expression, plasticity, homing potentials, and their reactivity to self-antigens
203 imaging shows that iNSCs are tumouritropic, homing rapidly to co-cultured glioblastoma cells and mig
204 s) are multiplexed, increasing the effective homing rate and decreasing the effective resistant allel
205 the vector, and then use the nuclease-based homing reaction as a form of gene drive to spread those
206 of different molecular processes during the homing reaction, various fitness effects, and the effica
207 ut it did decrease the expression of the gut-homing receptor alpha4beta7 on plasmacytoid dendritic ce
209 cells that express the vascular endothelium-homing receptor CX3CR1 (fractalkine receptor) are enrich
210 iquely defined by expression of the follicle-homing receptor CXCR5, the guidance receptor promoting t
214 unexpected role for lectin CD22 as a B-cell homing receptor GALT, and identification of the orphan G
218 ILC3, but not ILC2, undergo the RA-dependent homing receptor switch in gut-associated lymphoid tissue
219 tively analyzed the expression patterns of 9 homing receptors (CCR/CXCR) in naive and memory CD4+ and
220 cells alter their expression of homeostatic homing receptors and subsequently undergo apoptosis due
222 K cell lineage via regulation of a subset of homing receptors that respond to homeostatic ligands whi
223 a regulation of homeostatic and inflammatory homing receptors, and that in its absence KLF2-deficient
224 icient T cells had reduced expression of gut homing receptors, diminished production of inflammatory
227 matical model to estimate tolerable rates of homing-resistant allele generation to suppress a wild po
228 uppressed populations rapidly rebounding, as homing-resistant alleles have a significant fitness adva
229 with current designs, the slow emergence of homing-resistant alleles is expected to result in suppre
232 ting memory CD8 T cell pool expressing liver-homing/retention markers (CD69(+)CD103(+) CXCR6(+)CXCR3(
236 lls had gestationally regulated responses to homing signals and/or adhesion mechanisms that influence
243 signalling results in a defect in thymic HPC homing, suggesting the feedback regulation of thymic pro
244 To remedy this, we theoretically explore a homing system architecture in which guide RNAs (gRNAs) a
245 he recent development of a CRISPR-Cas9-based homing system for the suppression of Anopheles gambiae i
248 of human psoriatic epidermal cells and skin-homing T cells, JNJ-54271074 selectively inhibited strep
249 at, instead of preferentially infecting skin-homing T cells, VZV alters cell signaling and remodels s
250 ood and skin phenotypes and determining skin-homing T-cell functional properties are needed to establ
252 in (EPO)-EPO receptor (R) signaling promotes homing to BM and early engraftment of UCB CD34(+) cells.
253 ng hematopoietic stem/progenitor cell (HSPC) homing to BM have been assessed to improve UCB engraftme
255 or type 5, a chemokine receptor required for homing to GCs) and expand in lymph nodes (LNs) following
258 tion, T cell transendothelial migration, and homing to lymph nodes, all of which also depend on WASp.
260 rgan homing molecules, and impeded Treg cell homing to non-lymphoid organs, causing CD8(+) T-cell-med
263 mechanism by which cancer cells direct MDSC homing to primary tumor and suggests that targeting MDSC
266 igated the role of CCR5 in regulating T-cell homing to the atherosclerotic aorta and the functionalit
271 dard transplantation protocol relies on cell homing to the bone marrow after intravenous injection.
272 a pivotal director in multiple myeloma cell homing to the bone marrow and multiple myeloma progressi
274 ys an essential role in MM cell survival and homing to the bone marrow, and therefore represents a th
275 one marrow stromal cells and reduces MM cell homing to the bone marrow, in association with decreased
276 nscriptomic analyses confirmed that MM cells homing to the CHT displayed gene-expression differences
279 valuable model in which to study cancer cell homing to the hematopoietic niche and to establish a scr
281 CFCs with erythropoietin could enhance their homing to the ischemic site after transient middle cereb
282 pment of the cells in the lungs, followed by homing to the liver and to a joint afflicted with hemart
283 ma (LLC), an additional defect in tumor cell homing to the lungs and a resulting reduction in the num
287 factory hypothesis for salmon imprinting and homing to their natal stream is well known, but the endo
290 , their seasonal timing and possible return (homing) to western headwater tributaries where they were
291 nto the skin was independent of typical skin-homing trafficking receptors and instead required alpha4
292 cipate that coupling DO sequences with tumor-homing transduction domains can create a potentially val
293 in support of path integration, including a homing vector system that tracks movement relative to ho
295 use model, we demonstrate generation of lung-homing, virus-specific T effectors after influenza infec
296 marrow microvasculature, and thus for marrow homing, we conducted a first-in-humans clinical trial to
297 03(+) dendritic cells, which regulate T cell homing, were also reduced in mesenteric lymph nodes of i
299 n ECFCs highlighted its notable role in ECFC homing with erythropoietin priming (ECFCEPO, 147% +/- 14
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