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   1 europeptide F, the Drosophila neuropeptide Y homolog.                                                
     2 about the function of NRG2, the closest NRG1 homolog.                                                
     3 BPR (TAP-binding protein-related), a tapasin homolog.                                                
     4 cy with UTY, a Y-chromosome demethylase-dead homolog.                                                
     5 aligning short reads that are part of remote homologs.                                               
     6 ct functional properties in different enzyme homologs.                                               
     7 t in cells dependent on other anti-apoptotic homologs.                                               
     8 junctions (dHJs) that primarily include both homologs.                                               
     9  markedly different from the regulons of its homologs.                                               
    10 icting secondary structures for multiple RNA homologs.                                               
    11 ific sequence that was mapped but also other homologs.                                               
    12 g of function in functionally diverse enzyme homologs.                                               
    13             Arabidopsis contains two OsMYBS1 homologs.                                               
    14 t the cochaperone, activator of Hsp90 ATPase homolog 1 (Aha1), dramatically increased the production 
    15 e kinase V-Akt murine thymoma viral oncogene homolog 1 (AKT1), and the protease cathepsin H (CTSH), f
  
    17 IFICANCE STATEMENT The discovery that Atonal homolog 1 (Atoh1) governs the development of the sensory
  
  
    20 lood cells preferentially recruit Disc large homolog 1 (Dlgh1) and exclude protein kinase C (PKC)-the
    21 ype I receptor inhibition using dorsomorphin homolog 1 (DMH1) or CRISPR/Cas9 activin A receptor type 
    22 the zinc finger transcription factor Kruppel homolog 1 (Kr-h1), one of the key players in juvenile ho
    23 PGC1alpha binding partners is liver receptor homolog 1 (LRH-1; NR5A2), an orphan nuclear hormone rece
    24 lorectal tumors with epigenetic loss of MutL homolog 1 (MLH1) had lost or had lower levels of HES1 th
    25 er, Msh2-Msh6 or Msh2-Msh3 activate the MutL homolog 1 (Mlh1)-postmeiotic segregation 1 (Pms1) endonu
    26  silent mating type information regulation 2 homolog 1 (SIRT1), which deacetylates forkhead box o3 (F
    27 s related to the outgrowth of TMs was tweety-homolog 1 (TTYH1), which was highly expressed in a fract
    28 creased levels of glioma-associated oncogene homolog 1 and 2 (GLI1/GLI2) compared with naive cells.  
    29 FXR1 (fragile X mental retardation autosomal homolog 1), an RNA-binding protein, are critical to main
  
    31  Meg3 relied on functional enhancer of zeste homolog 2 (EZH2), a component of polycomb repressive com
    32 eraction between Snail and enhancer of zeste homolog 2 (EZH2), an enzymatic subunit of the polycomb-r
  
  
  
    36 e methyl transferase EZH2 (Enhancer of Zeste Homolog 2) is generally associated with H3K27 methylatio
    37 ore subunit of PRC2 (Ezh2 [enhancer of zeste homolog 2]) at the cell membrane, preventing its nuclear
  
    39 ere associated with upregulation of tribbles homolog 3 (Trib3) that suppressed adipogenic differentia
  
    41 centrin-binding site within H. sapiens Prp40 homolog A (HsPrp40A), which contains a hydrophobic triad
  
    43   Loss-of-function mutations of KIB1 and its homologs abolished BR-induced BIN2 degradation and cause
    44 e, we report on two potent ClpG disaggregase homologs acquired through horizontal gene transfer by th
    45 on of alpha-ketoglutarate, inhibits the AlkB homolog (ALKBH) enzymes activity and induces DNA alkylat
    46 We found that human, fly, and yeast profilin homologs all directly enhance microtubule growth rate by
    47 at in addition to a conserved function, UL37 homologs also have divergent virus-specific functions.  
    48  These results solidify Hrq1 as a true RecQ4 homolog and position it as the premier model to determin
    49 th the trimming ability of the fungal Hsp104 homolog and the strength of the [PSI(+)] variant: the gr
  
    51  greater the trimming activity of the Hsp104 homolog and the weaker the variant, the greater the curi
    52 Therefore, we cloned the maize Tel2 and Tti1 homologs and showed that TEL2 can interact with both TTI
  
    54 ), RAB5A, VPS35 (vacuolar protein sorting 35 homolog), and M6PR (mannose 6-phosphate receptor) blocke
    55 genes, including 292 disease resistance gene homologs, and nine genes determining essential oil chara
  
  
  
  
  
    61 d motif analyses indicated that XND1 and its homologs are present only in angiosperms and possess a h
  
    63 superfamily of methyltransferases, and Trm10 homologs are widely conserved throughout Eukarya and Arc
    64 suppressor gene PTEN (phosphatase and tensin homolog) are frequent events and are associated with the
  
  
  
    68 tol phosphatase PTEN (phosphatase and tensin homolog) as primarily responsible for defects in B lymph
  
  
    71 e kinase v-RAF murine sarcoma viral oncogene homolog B (BRAF(V600E)), oncogenic signaling enhances gl
  
    73 t betaCAs and includes the identification of homologs between species using phylogenetic approaches, 
  
    75  of the GtCCR2 SB occurs not from the Asp-96 homolog, but by proton return from the earlier protonate
    76 nhances covalent flavinylation of Complex II homologs, but the mechanisms underlying the covalent att
  
  
  
  
    81 cular functions, including how the mammalian homologs Cripto-1 and Cryptic recognize and regulate TGF
  
    83 phage migration inhibitory factor (MIF), its homolog D-dopachrome tautomerase (D-DT), and their commo
  
    85 rate that depletion of the single Drosophila homolog dBRWD3 results in altered gene expression and ab
    86  the loss of LKB1 and phosphatase and tensin homolog deleted on chromosome 10 (PTEN) induces activati
    87 the tumor suppressor, phosphatase and tensin homolog deleted on chromosome 10 (PTEN), alters the inva
  
    89 y and functionally closely related GalNAc-T3 homolog did not show compensatory functionality for effe
  
    91 ison of the two structures reveals that UL37 homologs differ in their overall shapes, distributions o
    92  by the phylogenetically conserved Doublesex homolog dmd-3, which is both required and sufficient for
  
    94   Here we show that knockdown of EAF2 or its homolog EAF1 sensitized prostate cancer cells to DNA dam
    95 or (HER3/ERBB3) and its catalytically active homologs EGFR and HER2 are essential for their signaling
    96  angiogenic potential of EMC10 and its mouse homolog (Emc10) in cultured endothelial cells and infarc
  
    98 cific to eutherian mammals because no direct homologs exist at the syntenic genomic locus in metather
    99 ripts encoding the Respiratory Burst Oxidase Homolog F, signaling components involved in ethylene and
   100 romotes the expression and activation of Ras homolog family member A (RhoA) and subsequent activation
   101 ed to the activation of the small GTPase Ras homolog family member A (RhoA) by the Galpha12/13 pathwa
   102      Here, we show that knocking out the Ras homolog family member A (RhoA) gene in normal fibroblast
  
   104 mponents (PotA, PotB, PotC, and PotD), while homologs for polyamine biosynthesis were conspicuously a
   105 ing conformations of a glutamate transporter homolog from archaebacterium Pyrococcus horikoshii, sodi
  
   107 es in their DNA-binding domains (DBDs), LANA homologs from Kaposi sarcoma-associated herpesvirus (KSH
  
   109 etic Z-rings formed by the bacterial tubulin homolog FtsZ, and the stabilization of the newly formed 
   110 sion correlates with increased levels of Ras homolog gene family, member A (RhoA), a KCTD13/CUL3 ubiq
   111 s, we created domain swaps between the close homologs Gpa2 and Rx1, which confer resistance in potato
   112 c Hsp90 homologs, whereas organellular Hsp90 homologs (Grp94 and TRAP1) are relatively insensitive to
  
  
  
  
  
  
   119 mmalian cells to show that these two EGF-CFC homologs have distinct, highly specific ligand binding a
   120 s and functional analyses of the human H2-Ob homolog, HLA-DOB, revealed both loss- and gain-of-functi
   121 gs of AtHY5 in monocots; however, AtHYH (HY5 homolog) homologs are absent in the monocots analyzed.  
   122 t that overexpression of cel-mir-237 and its homolog, hsa-miR-125b, functions as sensitizers to gamma
   123 teasome itself, these include the proteasome homolog HslV, which functions together with the AAA+ Hsl
  
   125 nown tumor necrosis factor (TNF) superfamily homolog in Drosophila, Coxiella-infected flies exhibit r
  
  
   128    In this study, we identified another OxyR homolog in V. cholerae, which we named OxyR2, and we ren
   129 h a potential role in root development, DRO1 homologs in Arabidopsis and peach showed root-specific e
   130  the SM regulator laeA, and deletion of mcrA homologs in Aspergillus terreus and Penicillum canescens
   131 is of exons regulated by ancient CELF family homologs in chicken, Drosophila, and Caenorhabditis eleg
   132 We have identified and characterized new ACR homologs in different cryptophyte species, showing that 
   133 evealed five glutamine amidotransferase-QueC homologs in Enterobacteria and Pseudomonas phage, and di
  
   135 survey of the wealth of information on human homologs in model organisms across numerous databases.  
   136 obacteria and Pseudomonas phage, and distant homologs in other phage and bacterial genomes, suggestin
  
  
  
  
   141 (rRNA) and 34 proteins, including 14 without homologs in the evolutionarily related bacterial ribosom
   142  protein interacts with P. blakesleeanus Ras homologs in yeast two-hybrid assays, indicating that Mad
  
  
  
   146 w fold and only 0.3L-2.3L effective sequence homologs, including one beta protein of 182 residues, on
   147 Trithorax-group proteins and their mammalian homologs, including those in BAF (mSWI/SNF) complexes, a
   148 efect caused by mutation of the nematode RD3 homolog is suppressed in vivo by mutation of key compone
   149  contacts for proteins without many sequence homologs is still of low quality and not very useful for
   150 hemotaxis by c-di-GMP through MapZ orthologs/homologs is widespread in proteobacteria and that the us
   151    K-Ras (Kirsten-rat sarcoma viral oncogene homolog) is a prominent oncogene that has been proven to
   152    This asymmetry, unobserved in other Hsp90 homologs, is due to buckling of one of the protomers and
  
   154  compared Kirsten rat sarcoma viral oncogene homolog (KRAS) mutations in pancreatic CTC and correspon
   155 ether the Kirsten rat sarcoma viral oncogene homolog (KRAS)-variant, a germline mutation in a microRN
   156 dimeric structure resolved for the bacterial homolog, LeuT, presumably because of a kink at TM12 prev
  
   158  cell differentiation and, together with its homolog LRF, supports CD4(+) T cell helper effector resp
  
  
  
  
  
  
   165 of succinyl-CoA, which is a close structural homolog of (2S)-methylsuccinyl-CoA and an essential inte
   166 falciparum and Toxoplasma gondii is FtsH1, a homolog of a bacterial membrane AAA+ metalloprotease.   
  
   168 we investigated whether Appl, the Drosophila homolog of App, could influence sleep-wake regulation wh
   169 ifically, we show that CUA-1, the C. elegans homolog of ATP7A/B, localizes to lysosome-like organelle
  
  
  
   173     We demonstrate that CKS1 is a functional homolog of CKS1/SUC1 and can physically interact with th
   174 ria but are also present in ATP7B, the human homolog of copA, and direct ribosomal frameshifting in v
  
  
  
   178 se data strongly suggest that MRV is a mouse homolog of HHV-6A, HHV-6B, and HHV-7.IMPORTANCE Herein w
  
  
   181 ng potential new biomarkers, a P. falciparum homolog of insulin-degrading enzyme (PfIDEh) met our sea
  
   183 study shows that mutations of HRPU-2, a worm homolog of mammalian hnRNP U, result in dysfunction of a
  
   185 ole in regulating the expression of SLO-2 (a homolog of mammalian Slo2) in Caenorhabditis elegans Los
  
   187      In addition, we show that the mammalian homolog of mRNA-cap, RNGTT, can replace mRNA-cap to play
   188 e show that Myoglianin (MYO), the Drosophila homolog of myostatin and GDF11, regulates not only body 
  
  
  
  
   193  the ETS domain of Ets-1, a close structural homolog of PU.1, 2:1 complex formation may represent an 
   194  F element-encoded protein TraR is a distant homolog of the chromosome-encoded transcription factor D
  
  
  
  
   199      Here, we identify Fft3, a fission yeast homolog of the mammalian SMARCAD1 SNF2 chromatin remodel
   200 a pseudoenzyme PDX1.2 that is a noncatalytic homolog of the PDX1 subunit of the vitamin B6 biosynthes
   201      They can therefore be viewed as the rat homolog of the primate anterior limb of the internal cap
   202 tors, we identified RPAP2 IYO Mate (RIMA), a homolog of yeast and human proteins linked to nuclear im
  
   204 work (TGN) depends on ECHIDNA (ECH), a plant homolog of yeast Triacylglycerol lipase (TLG2/SYP4) inte
   205      Here we show in mouse that ZFP804A, the homolog of ZNF804A, is required for normal progenitor pr
  
  
   208  functional analysis of two maize (Zea mays) homologs of At-NPF6.3 (Zm-NPF6.6 and Zm-NPF6.4) showed t
   209 d phylogenetic analysis, we identified three homologs of AtHY5 in monocots; however, AtHYH (HY5 homol
   210     LanC-like (LanCL) proteins are mammalian homologs of bacterial LanC enzymes, which catalyze the a
  
   212  both in shared expression patterns of wheat homologs of Brachypodium genes and functional overlap re
  
  
   215 e found that three pathways that include the homologs of Drosophila Dys, Trio, and Shot were downregu
  
   217 thaliana, the GLX system is encoded by three homologs of GLXI and three homologs of GLXII, from which
   218  encoded by three homologs of GLXI and three homologs of GLXII, from which several predicted GLXI and
  
  
   221  because its genome encodes a single TLR and homologs of many downstream signaling components, includ
  
   223 lants, we have characterized the Arabidopsis homologs of SEIPIN proteins, which are crucial factors f
   224 (SLs) that are predicted to form in MYB33/65 homologs of species as evolutionary distant as gymnosper
   225 dopsis (Arabidopsis thaliana) genome encodes homologs of the Guided Entry of Tail (GET)-anchored prot
   226 these loci colocalize with the B. distachyon homologs of the major flowering pathway genes VRN2 and F
   227  carbohydrate binding module (CBM48) and are homologs of the PROTEIN TARGETING TO STARCH (PTST) prote
   228 elated sequence has been added to the model, homologs of the unrelated sequence will also produce hig
  
   230 endent 5-oxoprolinase; most prokaryotes lack homologs of this enzyme (and the gamma-glutamyl cycle) b
   231 haracterization of novel phages that possess homologs of this GTA's structural and regulatory genes h
   232 to possess the RNase A superfamily fold, and homologs of this toxin are associated with secretion sys
  
   234  This pseudogene was flanked by C. porcellus homologs of two genes, FBXO3 and ORF91, a relationship a
   235 ve transfer of rabbit IgG against the murine homologs of two immunodominant fragments in adult C57BL/
  
  
   238 omozygous diploids, the presence of multiple homologs or homeologs in polyploids affords greater tole
   239 light, suggesting redundancy with other ELF3 homologs or possibly an alternative mode of action for t
  
   241 n this well-studied model, it is unclear how homolog pairing in diploids or environmental conditions 
  
   243   Meiotic synapsis and recombination between homologs permits the formation of cross-overs that are e
  
   245 sing a polymer model, we observe significant homolog proximity that increases in saturated culture co
  
  
  
   249  find here, using the phosphatase and tensin homolog (PTEN) pseudogene as a model system, that antise
   250 ion, higher levels of phosphatase and tensin homolog (PTEN), and diminished Akt phosphorylation.     
   251 umor-suppressor genes phosphatase and tensin homolog (PTEN), cyclin dependent kinase inhibitor 2A (CD
   252 diated degradation of phosphatase and tensin homolog (PTEN), which impaired intercellular junction fo
   253 ndrial damage induces Phosphatase and Tensin Homolog (PTEN)-induced Putative Kinase 1 (PINK1) and Par
   254 lization, we define a phosphatase and tensin homolog (PTEN)-regulated checkpoint that retains deltaR 
  
   256   Here, we show that Akt activation by a Ras homolog, R-Ras, stabilizes the microtubule cytoskeleton 
  
   258 g Mmp2 and Oamb can be replaced by its human homolog Ras-responsive element-binding protein 1 (RREB-1
   259 known function included transcription factor homologs related to oxidative stress by 3D-homology mode
   260 ein Imd leads to activation of the NF-kappaB homolog Relish and robust antimicrobial peptide gene exp
   261 he Arabidopsis uORF and its maize (Zea mays) homolog repressed the translation of the main open readi
   262 s2t6A and ct6A by depletion of tcdA and mtaB homologs, respectively, demonstrating that TcdA and MtaB
  
  
   265 ain specificity of antibodies was studied by homolog-scanning mutagenesis (HSM) with single human dom
  
  
  
  
  
  
   272 n, Mer2 is required for pairing by mediating homolog spatial juxtaposition, with implications for cro
  
  
   275 velopment and is less characterized than its homolog Tau, which has various roles in neurodegeneratio
  
   277 ein we show that mftE encodes a creatininase homolog that catalyzes cleavage of the oxidatively decar
   278 tal structures of BjaI, a CoA-dependent LuxI homolog that represent views of enzyme complexes that ex
   279  lost, resulting in an elevated frequency of homologs that do not receive a crossover, which in turn 
   280  of plant R-proteins, animal NLRs, and their homologs that represent the NB-ARC (nucleotide-binding a
  
   282 HFR-TS3) operates as an inhibitor of its two homologs, thus regulating DHFR and TS activities and, as
   283 nel to cations in GtCCR2 requires the Asp-96 homolog to be unprotonated, as has been proposed for the
   284 n (Ubqn), the ubiquitin receptor whose human homolog ubiquilin 2 is associated with familial amyotrop
   285  Drosophila, amorphic mutations in the KIF1A homolog unc-104 disrupt the formation of mature boutons.
  
  
   288 reted MSPds derived from the C. elegans VAPB homolog VPR-1 promote mitochondrial localization to acti
  
  
   291 language region extended to right-hemisphere homologs was positively associated with the time elapsed
  
   293 ls between use-dependent and use-independent homologs, we have determined the molecular basis that un
   294    Using a dataset that only contains remote homologs, we have shown that WSeqKernel performs remarka
  
   296 g ATPase inhibitor of cytosol-specific Hsp90 homologs, whereas organellular Hsp90 homologs (Grp94 and
   297 r secondary structure prediction of multiple homologs, whereby the mapping data benefits not only the
   298 c pathways dependent on the C. elegans PINK1 homolog, which is necessary for cellular resistance to c
   299 modifiers have functionally-similar X-linked homologs whose deficiency is involved in ccRCC progressi
   300 ariation at sector positions can distinguish homologs with a conserved dynamic pattern and optimal ca
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