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1 europeptide F, the Drosophila neuropeptide Y homolog.
2 about the function of NRG2, the closest NRG1 homolog.
3 BPR (TAP-binding protein-related), a tapasin homolog.
4 cy with UTY, a Y-chromosome demethylase-dead homolog.
5 aligning short reads that are part of remote homologs.
6 ct functional properties in different enzyme homologs.
7 t in cells dependent on other anti-apoptotic homologs.
8 junctions (dHJs) that primarily include both homologs.
9 markedly different from the regulons of its homologs.
10 icting secondary structures for multiple RNA homologs.
11 ific sequence that was mapped but also other homologs.
12 g of function in functionally diverse enzyme homologs.
13 Arabidopsis contains two OsMYBS1 homologs.
14 t the cochaperone, activator of Hsp90 ATPase homolog 1 (Aha1), dramatically increased the production
15 e kinase V-Akt murine thymoma viral oncogene homolog 1 (AKT1), and the protease cathepsin H (CTSH), f
17 IFICANCE STATEMENT The discovery that Atonal homolog 1 (Atoh1) governs the development of the sensory
20 lood cells preferentially recruit Disc large homolog 1 (Dlgh1) and exclude protein kinase C (PKC)-the
21 ype I receptor inhibition using dorsomorphin homolog 1 (DMH1) or CRISPR/Cas9 activin A receptor type
22 the zinc finger transcription factor Kruppel homolog 1 (Kr-h1), one of the key players in juvenile ho
23 PGC1alpha binding partners is liver receptor homolog 1 (LRH-1; NR5A2), an orphan nuclear hormone rece
24 lorectal tumors with epigenetic loss of MutL homolog 1 (MLH1) had lost or had lower levels of HES1 th
25 er, Msh2-Msh6 or Msh2-Msh3 activate the MutL homolog 1 (Mlh1)-postmeiotic segregation 1 (Pms1) endonu
26 silent mating type information regulation 2 homolog 1 (SIRT1), which deacetylates forkhead box o3 (F
27 s related to the outgrowth of TMs was tweety-homolog 1 (TTYH1), which was highly expressed in a fract
28 creased levels of glioma-associated oncogene homolog 1 and 2 (GLI1/GLI2) compared with naive cells.
29 FXR1 (fragile X mental retardation autosomal homolog 1), an RNA-binding protein, are critical to main
31 Meg3 relied on functional enhancer of zeste homolog 2 (EZH2), a component of polycomb repressive com
32 eraction between Snail and enhancer of zeste homolog 2 (EZH2), an enzymatic subunit of the polycomb-r
36 e methyl transferase EZH2 (Enhancer of Zeste Homolog 2) is generally associated with H3K27 methylatio
37 ore subunit of PRC2 (Ezh2 [enhancer of zeste homolog 2]) at the cell membrane, preventing its nuclear
39 ere associated with upregulation of tribbles homolog 3 (Trib3) that suppressed adipogenic differentia
41 centrin-binding site within H. sapiens Prp40 homolog A (HsPrp40A), which contains a hydrophobic triad
43 Loss-of-function mutations of KIB1 and its homologs abolished BR-induced BIN2 degradation and cause
44 e, we report on two potent ClpG disaggregase homologs acquired through horizontal gene transfer by th
45 on of alpha-ketoglutarate, inhibits the AlkB homolog (ALKBH) enzymes activity and induces DNA alkylat
46 We found that human, fly, and yeast profilin homologs all directly enhance microtubule growth rate by
47 at in addition to a conserved function, UL37 homologs also have divergent virus-specific functions.
48 These results solidify Hrq1 as a true RecQ4 homolog and position it as the premier model to determin
49 th the trimming ability of the fungal Hsp104 homolog and the strength of the [PSI(+)] variant: the gr
51 greater the trimming activity of the Hsp104 homolog and the weaker the variant, the greater the curi
52 Therefore, we cloned the maize Tel2 and Tti1 homologs and showed that TEL2 can interact with both TTI
54 ), RAB5A, VPS35 (vacuolar protein sorting 35 homolog), and M6PR (mannose 6-phosphate receptor) blocke
55 genes, including 292 disease resistance gene homologs, and nine genes determining essential oil chara
61 d motif analyses indicated that XND1 and its homologs are present only in angiosperms and possess a h
63 superfamily of methyltransferases, and Trm10 homologs are widely conserved throughout Eukarya and Arc
64 suppressor gene PTEN (phosphatase and tensin homolog) are frequent events and are associated with the
68 tol phosphatase PTEN (phosphatase and tensin homolog) as primarily responsible for defects in B lymph
71 e kinase v-RAF murine sarcoma viral oncogene homolog B (BRAF(V600E)), oncogenic signaling enhances gl
73 t betaCAs and includes the identification of homologs between species using phylogenetic approaches,
75 of the GtCCR2 SB occurs not from the Asp-96 homolog, but by proton return from the earlier protonate
76 nhances covalent flavinylation of Complex II homologs, but the mechanisms underlying the covalent att
81 cular functions, including how the mammalian homologs Cripto-1 and Cryptic recognize and regulate TGF
83 phage migration inhibitory factor (MIF), its homolog D-dopachrome tautomerase (D-DT), and their commo
85 rate that depletion of the single Drosophila homolog dBRWD3 results in altered gene expression and ab
86 the loss of LKB1 and phosphatase and tensin homolog deleted on chromosome 10 (PTEN) induces activati
87 the tumor suppressor, phosphatase and tensin homolog deleted on chromosome 10 (PTEN), alters the inva
89 y and functionally closely related GalNAc-T3 homolog did not show compensatory functionality for effe
91 ison of the two structures reveals that UL37 homologs differ in their overall shapes, distributions o
92 by the phylogenetically conserved Doublesex homolog dmd-3, which is both required and sufficient for
94 Here we show that knockdown of EAF2 or its homolog EAF1 sensitized prostate cancer cells to DNA dam
95 or (HER3/ERBB3) and its catalytically active homologs EGFR and HER2 are essential for their signaling
96 angiogenic potential of EMC10 and its mouse homolog (Emc10) in cultured endothelial cells and infarc
98 cific to eutherian mammals because no direct homologs exist at the syntenic genomic locus in metather
99 ripts encoding the Respiratory Burst Oxidase Homolog F, signaling components involved in ethylene and
100 romotes the expression and activation of Ras homolog family member A (RhoA) and subsequent activation
101 ed to the activation of the small GTPase Ras homolog family member A (RhoA) by the Galpha12/13 pathwa
102 Here, we show that knocking out the Ras homolog family member A (RhoA) gene in normal fibroblast
104 mponents (PotA, PotB, PotC, and PotD), while homologs for polyamine biosynthesis were conspicuously a
105 ing conformations of a glutamate transporter homolog from archaebacterium Pyrococcus horikoshii, sodi
107 es in their DNA-binding domains (DBDs), LANA homologs from Kaposi sarcoma-associated herpesvirus (KSH
109 etic Z-rings formed by the bacterial tubulin homolog FtsZ, and the stabilization of the newly formed
110 sion correlates with increased levels of Ras homolog gene family, member A (RhoA), a KCTD13/CUL3 ubiq
111 s, we created domain swaps between the close homologs Gpa2 and Rx1, which confer resistance in potato
112 c Hsp90 homologs, whereas organellular Hsp90 homologs (Grp94 and TRAP1) are relatively insensitive to
119 mmalian cells to show that these two EGF-CFC homologs have distinct, highly specific ligand binding a
120 s and functional analyses of the human H2-Ob homolog, HLA-DOB, revealed both loss- and gain-of-functi
121 gs of AtHY5 in monocots; however, AtHYH (HY5 homolog) homologs are absent in the monocots analyzed.
122 t that overexpression of cel-mir-237 and its homolog, hsa-miR-125b, functions as sensitizers to gamma
123 teasome itself, these include the proteasome homolog HslV, which functions together with the AAA+ Hsl
125 nown tumor necrosis factor (TNF) superfamily homolog in Drosophila, Coxiella-infected flies exhibit r
128 In this study, we identified another OxyR homolog in V. cholerae, which we named OxyR2, and we ren
129 h a potential role in root development, DRO1 homologs in Arabidopsis and peach showed root-specific e
130 the SM regulator laeA, and deletion of mcrA homologs in Aspergillus terreus and Penicillum canescens
131 is of exons regulated by ancient CELF family homologs in chicken, Drosophila, and Caenorhabditis eleg
132 We have identified and characterized new ACR homologs in different cryptophyte species, showing that
133 evealed five glutamine amidotransferase-QueC homologs in Enterobacteria and Pseudomonas phage, and di
135 survey of the wealth of information on human homologs in model organisms across numerous databases.
136 obacteria and Pseudomonas phage, and distant homologs in other phage and bacterial genomes, suggestin
141 (rRNA) and 34 proteins, including 14 without homologs in the evolutionarily related bacterial ribosom
142 protein interacts with P. blakesleeanus Ras homologs in yeast two-hybrid assays, indicating that Mad
146 w fold and only 0.3L-2.3L effective sequence homologs, including one beta protein of 182 residues, on
147 Trithorax-group proteins and their mammalian homologs, including those in BAF (mSWI/SNF) complexes, a
148 efect caused by mutation of the nematode RD3 homolog is suppressed in vivo by mutation of key compone
149 contacts for proteins without many sequence homologs is still of low quality and not very useful for
150 hemotaxis by c-di-GMP through MapZ orthologs/homologs is widespread in proteobacteria and that the us
151 K-Ras (Kirsten-rat sarcoma viral oncogene homolog) is a prominent oncogene that has been proven to
152 This asymmetry, unobserved in other Hsp90 homologs, is due to buckling of one of the protomers and
154 compared Kirsten rat sarcoma viral oncogene homolog (KRAS) mutations in pancreatic CTC and correspon
155 ether the Kirsten rat sarcoma viral oncogene homolog (KRAS)-variant, a germline mutation in a microRN
156 dimeric structure resolved for the bacterial homolog, LeuT, presumably because of a kink at TM12 prev
158 cell differentiation and, together with its homolog LRF, supports CD4(+) T cell helper effector resp
165 of succinyl-CoA, which is a close structural homolog of (2S)-methylsuccinyl-CoA and an essential inte
166 falciparum and Toxoplasma gondii is FtsH1, a homolog of a bacterial membrane AAA+ metalloprotease.
168 we investigated whether Appl, the Drosophila homolog of App, could influence sleep-wake regulation wh
169 ifically, we show that CUA-1, the C. elegans homolog of ATP7A/B, localizes to lysosome-like organelle
173 We demonstrate that CKS1 is a functional homolog of CKS1/SUC1 and can physically interact with th
174 ria but are also present in ATP7B, the human homolog of copA, and direct ribosomal frameshifting in v
178 se data strongly suggest that MRV is a mouse homolog of HHV-6A, HHV-6B, and HHV-7.IMPORTANCE Herein w
181 ng potential new biomarkers, a P. falciparum homolog of insulin-degrading enzyme (PfIDEh) met our sea
183 study shows that mutations of HRPU-2, a worm homolog of mammalian hnRNP U, result in dysfunction of a
185 ole in regulating the expression of SLO-2 (a homolog of mammalian Slo2) in Caenorhabditis elegans Los
187 In addition, we show that the mammalian homolog of mRNA-cap, RNGTT, can replace mRNA-cap to play
188 e show that Myoglianin (MYO), the Drosophila homolog of myostatin and GDF11, regulates not only body
193 the ETS domain of Ets-1, a close structural homolog of PU.1, 2:1 complex formation may represent an
194 F element-encoded protein TraR is a distant homolog of the chromosome-encoded transcription factor D
199 Here, we identify Fft3, a fission yeast homolog of the mammalian SMARCAD1 SNF2 chromatin remodel
200 a pseudoenzyme PDX1.2 that is a noncatalytic homolog of the PDX1 subunit of the vitamin B6 biosynthes
201 They can therefore be viewed as the rat homolog of the primate anterior limb of the internal cap
202 tors, we identified RPAP2 IYO Mate (RIMA), a homolog of yeast and human proteins linked to nuclear im
204 work (TGN) depends on ECHIDNA (ECH), a plant homolog of yeast Triacylglycerol lipase (TLG2/SYP4) inte
205 Here we show in mouse that ZFP804A, the homolog of ZNF804A, is required for normal progenitor pr
208 functional analysis of two maize (Zea mays) homologs of At-NPF6.3 (Zm-NPF6.6 and Zm-NPF6.4) showed t
209 d phylogenetic analysis, we identified three homologs of AtHY5 in monocots; however, AtHYH (HY5 homol
210 LanC-like (LanCL) proteins are mammalian homologs of bacterial LanC enzymes, which catalyze the a
212 both in shared expression patterns of wheat homologs of Brachypodium genes and functional overlap re
215 e found that three pathways that include the homologs of Drosophila Dys, Trio, and Shot were downregu
217 thaliana, the GLX system is encoded by three homologs of GLXI and three homologs of GLXII, from which
218 encoded by three homologs of GLXI and three homologs of GLXII, from which several predicted GLXI and
221 because its genome encodes a single TLR and homologs of many downstream signaling components, includ
223 lants, we have characterized the Arabidopsis homologs of SEIPIN proteins, which are crucial factors f
224 (SLs) that are predicted to form in MYB33/65 homologs of species as evolutionary distant as gymnosper
225 dopsis (Arabidopsis thaliana) genome encodes homologs of the Guided Entry of Tail (GET)-anchored prot
226 these loci colocalize with the B. distachyon homologs of the major flowering pathway genes VRN2 and F
227 carbohydrate binding module (CBM48) and are homologs of the PROTEIN TARGETING TO STARCH (PTST) prote
228 elated sequence has been added to the model, homologs of the unrelated sequence will also produce hig
230 endent 5-oxoprolinase; most prokaryotes lack homologs of this enzyme (and the gamma-glutamyl cycle) b
231 haracterization of novel phages that possess homologs of this GTA's structural and regulatory genes h
232 to possess the RNase A superfamily fold, and homologs of this toxin are associated with secretion sys
234 This pseudogene was flanked by C. porcellus homologs of two genes, FBXO3 and ORF91, a relationship a
235 ve transfer of rabbit IgG against the murine homologs of two immunodominant fragments in adult C57BL/
238 omozygous diploids, the presence of multiple homologs or homeologs in polyploids affords greater tole
239 light, suggesting redundancy with other ELF3 homologs or possibly an alternative mode of action for t
241 n this well-studied model, it is unclear how homolog pairing in diploids or environmental conditions
243 Meiotic synapsis and recombination between homologs permits the formation of cross-overs that are e
245 sing a polymer model, we observe significant homolog proximity that increases in saturated culture co
249 find here, using the phosphatase and tensin homolog (PTEN) pseudogene as a model system, that antise
250 ion, higher levels of phosphatase and tensin homolog (PTEN), and diminished Akt phosphorylation.
251 umor-suppressor genes phosphatase and tensin homolog (PTEN), cyclin dependent kinase inhibitor 2A (CD
252 diated degradation of phosphatase and tensin homolog (PTEN), which impaired intercellular junction fo
253 ndrial damage induces Phosphatase and Tensin Homolog (PTEN)-induced Putative Kinase 1 (PINK1) and Par
254 lization, we define a phosphatase and tensin homolog (PTEN)-regulated checkpoint that retains deltaR
256 Here, we show that Akt activation by a Ras homolog, R-Ras, stabilizes the microtubule cytoskeleton
258 g Mmp2 and Oamb can be replaced by its human homolog Ras-responsive element-binding protein 1 (RREB-1
259 known function included transcription factor homologs related to oxidative stress by 3D-homology mode
260 ein Imd leads to activation of the NF-kappaB homolog Relish and robust antimicrobial peptide gene exp
261 he Arabidopsis uORF and its maize (Zea mays) homolog repressed the translation of the main open readi
262 s2t6A and ct6A by depletion of tcdA and mtaB homologs, respectively, demonstrating that TcdA and MtaB
265 ain specificity of antibodies was studied by homolog-scanning mutagenesis (HSM) with single human dom
272 n, Mer2 is required for pairing by mediating homolog spatial juxtaposition, with implications for cro
275 velopment and is less characterized than its homolog Tau, which has various roles in neurodegeneratio
277 ein we show that mftE encodes a creatininase homolog that catalyzes cleavage of the oxidatively decar
278 tal structures of BjaI, a CoA-dependent LuxI homolog that represent views of enzyme complexes that ex
279 lost, resulting in an elevated frequency of homologs that do not receive a crossover, which in turn
280 of plant R-proteins, animal NLRs, and their homologs that represent the NB-ARC (nucleotide-binding a
282 HFR-TS3) operates as an inhibitor of its two homologs, thus regulating DHFR and TS activities and, as
283 nel to cations in GtCCR2 requires the Asp-96 homolog to be unprotonated, as has been proposed for the
284 n (Ubqn), the ubiquitin receptor whose human homolog ubiquilin 2 is associated with familial amyotrop
285 Drosophila, amorphic mutations in the KIF1A homolog unc-104 disrupt the formation of mature boutons.
288 reted MSPds derived from the C. elegans VAPB homolog VPR-1 promote mitochondrial localization to acti
291 language region extended to right-hemisphere homologs was positively associated with the time elapsed
293 ls between use-dependent and use-independent homologs, we have determined the molecular basis that un
294 Using a dataset that only contains remote homologs, we have shown that WSeqKernel performs remarka
296 g ATPase inhibitor of cytosol-specific Hsp90 homologs, whereas organellular Hsp90 homologs (Grp94 and
297 r secondary structure prediction of multiple homologs, whereby the mapping data benefits not only the
298 c pathways dependent on the C. elegans PINK1 homolog, which is necessary for cellular resistance to c
299 modifiers have functionally-similar X-linked homologs whose deficiency is involved in ccRCC progressi
300 ariation at sector positions can distinguish homologs with a conserved dynamic pattern and optimal ca
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