ライフサイエンスコーパス: homologous gene

1 ded by the RPE65 gene rather than by another homologous gene.

2 me segment and has been proposed to affect a homologous gene.

3 bacteria and red algae possess just one nblA-homologous gene.

4 c as a result of the disparate regulation of homologous genes.

5 o-sex chromosomes that contain a total of 12 homologous genes.

6 uman and mouse tumors or whether they affect homologous genes.

7 The annotations describe matches to human homologous genes.

8 quence similarity to transfer annotations to homologous genes.

9 and was conserved in >50% of human and mouse homologous genes.

10 NA (known as siRNA) inhibits expression from homologous genes.

11 ery different reactions, they are encoded by homologous genes.

12 s or non-native probes derived from putative homologous genes.

13 create multiple crossover libraries from non-homologous genes.

14 randed RNA by sequence-specific silencing of homologous genes.

15 sponds to double-stranded RNA by suppressing homologous genes.

16 nce sequence the positions of all introns in homologous genes.

17 represented in the mouse by a cluster of six homologous genes.

18 ifficulty in studying expression patterns of homologous genes.

19 e results shed light on the evolution of X-Y homologous genes.

20 idual loops that were of comparable size for homologous genes.

21 ve been discovered by chance or by searching homologous genes.

22 bit a low level of amino acid identity among homologous genes (20 to 59%), perhaps reflecting a signi

23 The interactions between MITEs and homologous genes across 19 accessions provided a fine so

24 Two adjacent homologous genes (alpA and alpB), which encode H. pylori

25 ults support the hypothesis that exchange of homologous genes among S. aureus genomes can play a role

26 nal BLAST searches that are used to identify homologous genes and combine them into two fundamentally

27 phs' to represent the assembly of reads from homologous genes and discuss potential applications of g

28 information in the public domain concerning homologous genes and their products increases greatly.

29 genomic context in operons containing other homologous genes, and distributions of conserved surface

30 . cruzi genome contains a large family of TS homologous genes, and it has been suggested that TS homo

31 es abundance, similarity between isoforms or homologous genes, and large data size all pose challenge

32 ganization, the low level of conservation of homologous genes, and the lack of many genes conserved i

33 y relevant cis-regulatory sequence change in homologous genes, and validate it using microarray data

34 Clusters of two or more homologous genes are abundant, totaling 1391 clusters co

35 mary literature, articles about well-studied homologous genes are added as references.

36 , and B. afzelli), suggesting that all three homologous genes are important to the maintenance of Lym

37 We show that homologous genes are present, and expressed, in a wide r

38 Although these homologous genes are required absolutely for recombinati

39 from the pea FTase allowed the cloning of a homologous gene, AtFT1, from Arabidopsis.

40 nd atTIC40, encode the Tic proteins, and two homologous genes, atHSP93-V and atHSP93-III, encode Hsp9

41 hosphate)-binding cassette (ABC) transporter-homologous gene, ATP11A.

42 yet no mutations have been described in the homologous genes beta- and gamma-synuclein.

43 A comparison of homologous genes between B. schlosseri and other diverse

44 In a comparison of the genomic sequences of homologous genes between C.elegans and Caenorhabditis br

45 r the conservation of expression patterns of homologous genes between distantly related species.

46 Substitution analysis of homologous genes between human and rodent also indicates

47 entists study macrosynteny, microsynteny and homologous genes between sequences.

48 Exchange of homologous genes between the two organisms showed that t

49 This signal specifies the cardiac field, and homologous genes (BMP2/4 and Nkx2.5) perform this functi

50 mLAR1 and HmLAR2, are products of different, homologous genes, both containing two tandem intracellul

51 -stranded RNA (dsRNA) inhibits expression of homologous genes by a process involving messenger RNA de

52 rely heavily on pre-computation to identify homologous genes by genome-wide comparisons.

53 onserved in Caenorhabditis elegans, in which homologous genes (called lin-2, lin-7, and lin-10) are r

54 ingle nucleotide changes, translocations and homologous genes can easily be extracted.

55 which is a process by which the proximity of homologous genes can lead to a change in gene expression

56 Interactions between paired homologous genes can lead to changes in gene expression.

57 to the formation of novel structures and how homologous genes can regulate the disparate morphologica

58 oteins encoded by the reductive dehalogenase homologous genes CbdbA1092 and CbdbA1503 were specifical

59 found to be produced by the highly conserved homologous gene (Cbfa2t1) in the mouse, suggesting an ev

60 The murine CD1 locus contains two highly homologous genes, CD1d1 and CD1d2.

61 atients retain at least one copy of a highly homologous gene, centromeric SMN ( SMN2 ).

62 We demonstrate here that the homologous gene cluster pilABCD in an otitis media isola

63 fungal symbiont, Neotyphodium uncinatum, two homologous gene clusters (LOL-1 and LOL-2) associated wi

64 Among a large number of homologous gene clusters in C. elegans, two gene familie

65 S. meliloti as suggested by the presence of homologous gene clusters in other bacterial genomes.

66 Pan-genome analysis identified 10,110 homologous gene clusters present only in a subset of str

67 A total of 331 homologous gene clusters were essential for fitness duri

68 Homologous gene clusters were found in genomes of other

69 While the homologous genes complement lethality of the QSR1 deleti

70 In addition, we annotate the homologous genes containing cysteine (Cys) instead of Se

71 Because homologous genes control early developmental events as w

72 rs through both homologous crossing over and homologous gene conversion during meiosis.

73 t to high levels of recombination as well as homologous gene conversion, indicating that patterns pro

74 A set of homologous genes could be identified in Brassica napus t

75 ch in Arabidopsis thaliana is encoded by two homologous genes, CSN5A and CSN5B.

76 Plasmids carrying homologous genes cut at appropriate sites recombined eff

77 e DNA diversity of a noncoding region of the homologous genes DD44Y and DD44X, sampling S. latifolia

78 er-1106, observed in HRR25 (CKIdelta/epsilon homologous gene)-deleted Saccharomyces cerevisiae cells

79 during remodeling of the endometrium, and a homologous gene, derailed, is known to regulate muscle a

80 Comparative analysis of inferred homologous genes derived from this model shows patterns

81 aracterized the full-length cDNAs of 3-OST-1 homologous genes, designated as 3-OST-2, 3-OST-3A, and 3

82 nts KB25/pKJB5 at 44 degrees C, but the less homologous gene does not.

83 These two homologous genes encode small proteins containing a calc

84 oremediation of chlorinated solvents, reveal homologous genes encoding an incomplete Wood-Ljungdahl p

85 d IRX10 and IRX10-like (IRX10-L), two highly homologous genes encoding members of the glycosyltransfe

86 quencies of apparent gene conversion between homologous genes encoding outer membrane proteins.

87 Several homologous genes encoding proteins involved in regulatin

88 Mammals have three homologous genes encoding proteins with hyaluronan synth

89 Four homologous genes encoding SAPAP proteins have been previ

90 reonine protein phosphatase1) and FyPP3, two homologous genes encoding the catalytic subunits of prot

91 reonine protein phosphatase1) and FyPP3, two homologous genes encoding the catalytic subunits of Ser/

92 clude rapid cold-induced expression of three homologous genes encoding transcriptional activators, CB

93 The phenylalanine ammonia-lyase homologous gene encP from the "Streptomyces maritimus" e

94 yndrome) led us to study the role of two non-homologous genes, EVC and LBN, in heart development and

95 No homologous gene exists in any (non-H. pylori) organism.

96 Characterization of p44-homologous genes expressed by the HGE agent in a tissue

97 This map was then compared to homologous gene expression in zebrafish, mouse, and shar

98 conserved, one possible model to account for homologous gene expression patterns, is conservation of

99 rom across-tissue differential expression to homologous gene expression.

100 HME results from mutations in one of two homologous genes, EXT1 and EXT2.

101 ssed gene display for the analysis of highly homologous gene families as demonstrated by its applicat

102 e can infer rooted species phylogenies using homologous gene families from complete genomes of 10 bac

103 blished sequences, and to detect potentially homologous gene families in both P. falciparum and Plasm

104 n dorsal columns of fly neurectoderm, and of homologous gene families in corresponding domains of ver

105 The differential gain and loss of genes from homologous gene families represents an important source

106 ntraction of KIR haplotypes as well as other homologous gene families that map in tandem.

107 structural and functional gene annotations, homologous gene families, multiple sequence alignments,

108 ncluding trinucleotide repeat expansions and homologous gene families, to facilitate their functional

109 ies phylogeny based on 36 genomes with 8,332 homologous gene families.

110 We have identified the homologous gene family (Rbm) on the mouse Y with a view

111 In vitro recombination of homologous genes (family shuffling) has been proposed as

112 Patterns of homologous gene flow among genomes of 12 strains from a

113 Homologous genes for both C-P lyase and phosphonatase de

114 ion, including the convergent recruitment of homologous genes for venom expression.

115 to explore the expression of this gene and a homologous gene, Foxp1, in the developing brain.

116 d by virus-mediated, transient expression of homologous gene fragments.

117 Both the homologous gene from E. faecalis V583 (EF1861) and E. co

118 on and molecular characterization of an ORC4-homologous gene from maize argues that, in its evolution

119 mid based expression of plmT2 or fos ORF4 (a homologous gene from the fostriecin biosynthetic gene cl

120 Cloning of the homologous gene from the mouse revealed 93% amino acid h

121 a coli, a gene fragment corresponding to the homologous gene from the pathogenic oral bacterium Porph

122 We have cloned and sequenced the homologous gene from Xenopus (Xenopus Dna2).

123 Our study identified homologous genes from Arabidopsis thaliana with known fu

124 and DeltaPpGbeta2 can be complemented by the homologous genes from Arabidopsis, AtXLG2 and AtAGB1, re

125 urther confirmation of this interaction, the homologous genes from Chlamydia trachomatis, serovar E,

126 acids that showed significant similarity to homologous genes from crayfish, insects, earthworms, and

127 targets are located at the same position in homologous genes from different plants; these either cou

128 rameshift signals are present in at least 21 homologous genes from different species, 2 of which are

129 homologous genes from each group underlie quantitative t

130 difficulties in metagenomic assembly is that homologous genes from evolutionarily closely related spe

131 soflavone synthase, and used them to isolate homologous genes from other leguminous species including

132 s but can be replaced by at least one of the homologous genes from other pathways.

133 share significant sequence similarities with homologous genes from other plants, the clade-specific f

134 uding ESTs derived from duplicated genes and homologous genes from related species.

135 validated by qRT-PCR, and compared with the homologous genes from S. japonica, a species in the same

136 e C4-Pepc and C4-Me genes from maize and the homologous genes from sorghum (Sorghum bicolor) and Seta

137 analysis of sequences from gene families and homologous genes from species of varying divergence can

138 To rectify this problem, we compare homologous genes from the budding yeast Saccharomyces ce

139 es encoding ShMKS1 and ShMKS2 as well as the homologous genes from the cultivated tomato, Solanum lyc

140 ation among these editases, we have isolated homologous genes from the Japanese pufferfish, Fugu rubr

141 or a convergent gene fusion involving a MutS-homologous gene functioning within the mitochondrion and

142 and their mechanism of export, we cloned the homologous genes (glnA1 and sodA) from the rapid-growing

143 ation genes, like the glutathione peroxidase homologous gene GPXH/GPX5 and the sigma-class glutathion

144 sharing a core cis-regulatory motif and each homologous gene group as sharing a homologous cis-regula

145 roup of genes specified by the user or among homologous gene groups; (3) inter-database comparative v

146 An unproven assumption is that homologous genes have a common ancestor.

147 Homologous genes have recently been shown to regulate st

148 Although homologous genes have yet to be inactivated in any other

149 ons and is mapped to chromosome 17; a highly homologous gene, hUAT2, maps to a nearby region of chrom

150 the single-gene-deficient mice by the intact homologous gene (i.e., hsp70.3 in hsp70.1-/- mice and vi

151 rged substantially, making identification of homologous genes impossible despite a separation of only

152 we demonstrate the expression pattern of the homologous gene in adult mouse brain and early mouse emb

153 obolus heterostrophus Hypothesizing that the homologous gene in Coccidioides posadasii could be impor

154 A targeted deletion of the homologous gene in Listeria was generated, and in contra

155 Knockout of the homologous gene in zebrafish recapitulated a heart failu

156 rice and barley and to a lesser extent with homologous genes in Arabidopsis.

157 Conserved effects on sleep-like behaviour of homologous genes in C. elegans and Drosophila suggest a

158 ips) for obtaining sequence information from homologous genes in closely related species.

159 omparisons of intron-exon structures between homologous genes in different eukaryotic species have re

160 he same ligand to regulate the expression of homologous genes in different organisms.

161 tive mapping, which compares the location of homologous genes in different species, is a powerful too

162 The existence of homologous genes in diverse species is intriguing.

163 volved, and map-based cloning identified two homologous genes in duplicated regions of the genome.

164 There are two RAD54-homologous genes in human cells, hRAD54 and RAD54B.

165 We now report the identification of homologous genes in humans and mice encoding MGAT2.

166 ided important insights into the function of homologous genes in humans, such studies are necessarily

167 biosis genes are CASTOR and POLLUX, the twin homologous genes in Lotus japonicus that encode putative

168 on, they can be used to overexpress specific homologous genes in M. maripaludis.

169 ngus and is unique to filamentous fungi, but homologous genes in Magnaporthe, Ustilago, Aspergillus,

170 Mrr superfamily of homologous genes in microbial genomes restricts modified

171 ms and by analyzing site-specific changes in homologous genes in model systems such as the yeast Sacc

172 pported by independent expression data or by homologous genes in other species.

173 Homologous genes in plants including rice and potato ind

174 unavailable, thus sequence comparison among homologous genes in present-day organisms forms the core

175 were made to induce the four annotated Xa27 homologous genes in rice cultivar Nipponbare, but none o

176 genes had been completed, reports of sets of homologous genes in several species of Gram-negative pla

177 imated that a minimum copy number of the p44-homologous genes in the genome is 18; (v) detected two d

178 ifferent mRNAs that are transcribed from p44-homologous genes in the HGE agent cultivated in HL-60 ce

179 Knockout or knockdown of the homologous genes in the higher plant model Arabidopsis t

180 dentification and characterization of highly homologous genes in the invertebrates Caenorhabditis ele

181 By contrast, knockouts of homologous genes in the mouse often do not exhibit compa

182 milar intron architecture, and therefore the homologous genes in these fungi are likely to use the sa

183 Distantly homologous genes in this region, US7, US8, US9, and US10

184 n subsequent generations, and can inactivate homologous genes in trans.

185 However, the deletion of the homologous genes in Y. pseudotuberculosis does not seem

186 By comparing yapK and yapJ to three homologous genes in Y. pseudotuberculosis IP32953 (YPTB0

187 For example, they share nine non-redundant homologous genes, including ribonucleotide reductase sma

188 , by connecting contigs with the guidance of homologous genes-information that is orthogonal to the s

189 Based on the presumed function of homologous genes involved in the biosynthesis of thiovir

190 ing animals and plants share common cores of homologous genes involved in the key processes of viral

191 I-PpoI-induced contact between homologous genes is abrogated by the transcriptional inh

192 nts a conserved linkage because the order of homologous genes is conserved.

193 d proposed that the functional similarity of homologous genes is primarily determined by the cellular

194 w report that the differential regulation of homologous genes is the mechanism responsible for the di

195 nes EGD-e and L. innocua CLIP 11262, contain homologous genes (lmo2764 and lin2907, respectively) tha

196 However, a handful of genes, including the homologous genes LNK1 and LNK2, are more strongly induce

197 Thus, two highly homologous genes, located in a head-to-head configuratio

198 and PCR analyses revealed disruption of the homologous gene locus in one fbpA::OmegaKm transformant

199 On the other hand, the order of exons within homologous genes (<2.5 kb) was preserved, as expected.

200 that the shared and divergent parts of these homologous genes may be involved in specifying the share

201 Nucleotide identities of homologous genes mostly varied by less than 1% within po

202 Deletion of two homologous genes, MRS3 and MRS4, that encode mitochondri

203 In addition to NY-BR-1, a homologous gene, NY-BR-1.1, was identified in this study

204 henomenon in which silencing among dispersed homologous genes occurs.

205 OsbHLH068, which is a homologous gene of AtbHLH112 that is up-regulated under

206 Gene-targeted knockdown of CYP2C55, the homologous gene of CYP2C9, demonstrated viability rescue

207 of Staphylococcus epidermidis, but not in a homologous gene of the more aggressive human pathogen, S

208 or why the same mutation in highly conserved homologous genes of different species leads to different

209 H. saguini contains homologous genes of known virulence factors found in oth

210 egions of extreme codon conservation between homologous genes of related species.

211 G5-like and D1-like genes of Ddp5 and in the homologous genes of the Ddp1, Dmp1, and Dmp2 plasmids we

212 and that none of them can be replaced by the homologous genes of the other mce operons.

213 human PTTG family consists of at least three homologous genes, of which PTTG1 is located on chromosom

214 We also identified a homologous gene on the Mus musculus X chromosome (MMUX)

215 ugView is a Java application for visualizing homologous genes on a pair of related genomes, and can a

216 Clustering of co-expressed, non-homologous genes on chromosomes implies their co-regulat

217 rangements in linear order were revealed for homologous genes on these two chromosomes that are total

218 If the two groups consist of two homologous genes, one from each individual, the IBD is c

219 le sets of chemotaxis genes, the deletion of homologous genes or even different genes in the same ope

220 lignments and trees representing families of homologous genes or proteins.

221 ome) can be assigned to one of two groups: X-homologous genes or testis-specific gene families with n

222 the molecular basis of how these two highly homologous genes orchestrate their diverse functions rem

223 rom multiple sequence alignments of putative homologous genes (orthologs and paralogs) and further ut

224 KEY MESSAGE: The homologous genes OsbHLH068 and AtbHLH112 have partially

225 Here, two rice CCR4 homologous genes, OsCCR4a and OsCCR4b, were identified.

226 s displaying V(D)J-mediated immunity, and no homologous gene pair has been identified in other organi

227 of this question we asked whether mouse X-Y homologous gene pairs are expressed in brain in a sex-sp

228 Structural variations distinguish homologous gene pairs characterized by divergent promote

229 gate the partial coding sequence for 56 more homologous gene pairs from the neo-sex chromosomes.

230 Approximately 12 X-Y homologous gene pairs have been identified in the non-re

231 ust to gene expression levels and removal of homologous gene pairs.

232 mutations in PDE6A and those reported in the homologous gene PDE6B encoding the beta subunit of rod c

233 Work on homologous genes present in Escherichia coli suggests th

234 The homologous gene product of myxomavirus (MV), M153R, was

235 21, but not in the syp122 mutant lacking the homologous gene product; the delay was rescued by comple

236 This process often yields homologous gene products exhibiting diverse functions.

237 of the Hpa RXLR effector gene HaRxL96 and a homologous gene, PsAvh163, from the Glycine max (soybean

238 plication events can be used to discriminate homologous genes, QuartetS uses an approximate phylogene

239 ccharomyces cerevisiae where deletion of the homologous gene RAD27 results in genome instability and

240 apeutic agents in gene therapy by initiating homologous gene recombination and repair.

241 ing, c-IAP1-deficient mice were generated by homologous gene recombination.

242 at removing low quality clusters of putative homologous genes recovered by heuristic-based approaches

243 The family is composed of five highly homologous genes referred to as TAFA-1 to -5.

244 erial symbionts and pathogens each contain a homologous gene region necessary for the synthesis and t

245 Four homologous genes regulated as part of the AFT1-regulon (

246 herefore, by combining chemical genetics and homologous gene replacement in somatic cells, we reveal

247 Using mutagenesis and homologous gene replacement in Tetrahymena thermophila,

248 analysis of an archaeon, we have developed a homologous gene replacement strategy for Halobacterium s

249 LEU2 was replaced by ADE1, preventing simple homologous gene replacement to become Leu2(+).

250 sertional mutagenesis, chemical mutagenesis, homologous gene replacement, conditional knockdown techn

251 thaliana accessions, this locus contains two homologous genes, RPW8.1 and RPW8.2.

252 We examined sequence variation in 18 homologous gene segments (including nearly 10,000 base p

253 g the CREB gene by transfecting cells with a homologous gene sequence double-stranded RNA drastically

254 ic applications, with particular emphasis on homologous gene sequences among mammals.

255 here was specific competition for binding by homologous gene sequences but not by pUC nor Bacillus su

256 ication designed for comparative analysis of homologous gene sequences either from multigene families

257 and unique short (US) genomic regions, where homologous genes share a high degree of colinearity and

258 f DNA and amino acid identity for 65% of the homologous genes shared by the two genomes.

259 he 4A3 mRNAs and that these otherwise highly homologous genes show different exon-intron distribution

260 Comparison of expression of eight ABI5-homologous genes shows overlapping regulation by ABI3, A

261 Homologous gene silencing was validated by reverse trans

262 are the expression pattern with those of the homologous genes SorCS1 and SorCS2.

263 those in genes with a small number of known homologous gene structures, show a significant correlati

264 on of functional features of dog-human-mouse homologous genes suggests that the dog might have underg

265 Finally, we identify a homologous gene, syne-2, that is expressed in an overlap

266 Recent studies entailing homologous gene targeting and mutation of WI-1 have prov

267 The relative frequency of homologous gene targeting was approximately one allelic

268 in C. albicans CAI4 was readily disrupted by homologous gene targeting, but efforts to disrupt the se

269 We created an Ercc1 mutant through homologous gene targeting.

270 e function has been hampered by obstacles to homologous gene targeting.

271 ted lactoferrin knockout (LFKO(-/-)) mice by homologous gene targeting.

272 we generated mice deficient in XIAP through homologous gene targeting.

273 In addition, there are four TipE-homologous genes (TEH1-4) in D. melanogaster and three t

274 In a nonrestoring genotype we identified a homologous gene that exhibits a deletion in the promoter

275 numerous pseudoparalogs were detected, i.e. homologous genes that apparently were acquired by early

276 t it is composed of approximately 100 highly homologous genes that are found only in mycobacteria.

277 RGA and GAI are homologous genes that encode putative transcriptional re

278 ogs are two fundamentally different types of homologous genes that evolved, respectively, by vertical

279 We show that Nematostella uses homologous genes to achieve bilateral symmetry: Multiple

280 ion systems create opportunities for testing homologous genes to increase competence of transformatio

281 Cosuppression, the silencing of dispersed homologous genes triggered by high copy number, may have

282 sed in Escherichia coli strains in which the homologous gene was mutated.

283 nment of sea urchin gene models to groups of homologous genes was accomplished by BLAST alignment and

284 An algorithm for detecting local clusters of homologous genes was applied to the genome of Caenorhabd

285 correlation of transposition hot spots among homologous genes was poor.

286 UTR1, cytosolic NAD kinase, and YEF1, a UTR1-homologous gene we characterized as encoding a low speci

287 Mutations in homologous genes were identified in the barley eceriferu

288 Homologous genes were subsequently identified in other i

289 Two homologous genes were suggestively associated: BCOR (Xp1

290 e source of diversity is naturally occurring homologous genes, which provide 'functional diversity'.

291 50 (CYP) 2B1 and 2B2 proteins are encoded by homologous genes whose promoters contain a mammalian-app

292 strain of H. ducreyi (35000HP) contains two homologous genes whose protein products have estimated m

293 for the simultaneous inactivation of several homologous genes with a single transgene.

294 method for simultaneously identifying novel homologous genes with identical structure in the human,

295 screens are limited in the identification of homologous genes with overlapping functions.

296 ay profile of mammalian nociceptors revealed homologous genes with potentially shared nociceptive fun

297 hat regulatory interactions between pairs of homologous genes within the same cell can lead to under-

298 hereas the expression of YOL002c and a third homologous gene, YOL101c, was induced by high zinc.

299 to reflect the presence of a second, highly homologous gene, ZmMrp4, that is also coregulated with t

300 described within the products of two, highly homologous genes: ZNF198/RAMP/FIM and ZNF261/DXS6673E.