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1 aments consist entirely of a single isoform (homotypic).
2 N1)pdm09 recipients, the PPAb titers against homotypic A(H1N1)pdm09 vaccine were similar to those aga
5 CD74 on MCL cells by the HexAbs resulted in homotypic adhesion and triggered intracellular changes t
8 o aggregation are not fully accounted for by homotypic adhesion, and that further factors influence t
9 sible for its unique properties of increased homotypic adhesion, apoptosis resistance and budding.
12 of leukocyte migration that is initiated by homotypic adhesive interactions between platelets, leadi
14 human neutrophils causes rapid (</= 30 min) homotypic aggregation and NET release by a mechanism tha
16 undergo a rapid, ECM-dependent mechanism of homotypic aggregation and NETosis in response to C. albi
22 eterotypic enhancers are stronger than their homotypic analogs and favor specific transcription facto
23 ignaling mechanism for pseudokinases whereby homotypic and heterotypic association is used to assembl
24 targeting sequence, and participates in both homotypic and heterotypic associations with itself and L
26 ace and programed cell-cell adhesion between homotypic and heterotypic cells via sequence-specific DN
27 ble, with rates of disorders and patterns of homotypic and heterotypic continuity similar to those ob
30 ted by the ability of Hax-1 proteins to form homotypic and heterotypic dimers with binding affinities
34 A (NTD and CTD, respectively) engage in both homotypic and heterotypic interactions to create the cap
35 s share highly conserved C-termini mediating homotypic and heterotypic interactions within and betwee
38 ional intercellular communication in several homotypic and heterotypic populations by visualizing the
40 ls are an important statistical correlate of homotypic and heterotypic response and may limit severit
51 equently observed, the mechanistic basis for homotypic binding site synergy is poorly understood.
56 functions as a retention factor, increasing homotypic cell adhesion and limiting tumor spreading to
63 cell death initiated by actomyosin-dependent homotypic cell-in-cell invasion that can be observed in
64 Therefore, our data uncover the existence of homotypic cell-to-cell communication among mobile innate
67 TFs, helping to explain the observation that homotypic chains of binding sites express at low levels.
70 act as direct drivers of gene expression in homotypic clusters of binding sites, independent of spac
71 ltiple copies of single mRNAs organize into 'homotypic clusters' that occupy defined positions within
73 absence of coupling for these mutants in the homotypic configuration could be explained by shifts in
74 KIT mutations, reveals that the strength of homotypic contacts and the cooperativity in the action o
75 ative interactions mediated by multiple weak homotypic contacts between receptor molecules are respon
78 uture occurrences of both the same disorder (homotypic continuity) and other disorders (heterotypic c
82 gardless of the specific type of GJ channel (homotypic Cx43 and Cx45, and heterotypic Cx43/Cx45 and C
83 ermore, these mutations induced formation of homotypic DC clusters, which represent close correlates
86 rate phages that are either closely related (homotypic defence) or unrelated (heterotypic defence) to
89 ally forms heterodimers with Dpp rather than homotypic dimers, providing a possible explanation for t
91 have evolved means to preferentially take up homotypic DNA containing short and genus-specific sequen
92 cadherin recapitulated this outcome, whereas homotypic E-cadherin engagement promoted apoptotic signa
93 r attachment protein receptors [SNAREs]) and homotypic endoplasmic reticulum (ER) fusion (Sey1p) for
99 Cells were recombined and cultured as either homotypic [(F(C))(E(C)) and (F(N))(E(N))] or heterotypic
101 lysosome depends on the GTPase Rab7 and the homotypic fusion and protein sorting (HOPS) complex, but
102 ein and subunit of the Vps-C complexes HOPS (homotypic fusion and protein sorting) and CORVET (class
103 We find that the tethering complex HOPS (homotypic fusion and protein sorting); the small GTPases
105 ations in the vacuolar tether complex, HOPS (HOmotypic fusion and vacuolar Protein Sorting complex).
106 -to-lysosomal trafficking, controlled by the homotypic fusion and vacuole protein sorting (HOPS) comp
108 lian homolog of yeast VPS41, a member of the homotypic fusion and vacuole protein sorting (HOPS) comp
109 vacuole/lysosome, they are integrated by the homotypic fusion and vacuole protein sorting (HOPS) comp
113 lysosome fusion in a manner dependent on the homotypic fusion and vacuole protein sorting (HOPS) teth
114 Qc-SNARE Vam7p is a binding partner for the homotypic fusion and vacuole protein sorting complex (a
116 amily GTPase Ypt7p and its effector complex, homotypic fusion and vacuole protein sorting complex (HO
117 nd that this permeabilization is enhanced by homotypic fusion and vacuole protein sorting complex (HO
118 phate (PI3P) and the tethering complex HOPS (homotypic fusion and vacuole protein sorting complex), w
120 C core vacuole/endosome tethering) and HOPS (homotypic fusion and vacuole protein sorting) tethering
121 e Vps34p, and Vps39p, a subunit of the HOPS (homotypic fusion and vacuole protein sorting) tethering
122 etrameric adaptor protein complex) and HOPS (homotypic fusion and vacuole protein sorting)-tethering
124 ctures of Vps33, the SM subunit of the yeast homotypic fusion and vacuole protein-sorting (HOPS) comp
125 omes via an interaction with the class C Vps/homotypic fusion and vacuole protein-sorting (HOPS) comp
126 mutations disrupting all six members of the homotypic fusion and vacuole protein-sorting (HOPS) mult
134 coding the atlastin-1 GTPase, which mediates homotypic fusion of ER tubules to form the polygonal ER
137 wo distinct processes: microtubule-dependent homotypic fusion of mLDs and expansion of individual mLD
139 1 that implicates the SNARE protein VTI11 in homotypic fusion of protein storage and lytic vacuoles.
140 autophagosomal machinery to CCVs for optimal homotypic fusion of the Coxiella-containing compartments
142 Like other intracellular fusion events, the homotypic fusion of yeast vacuoles requires a Rab GTPase
147 lar compound events (i.e. granule-to-granule homotypic fusion) was severely reduced in the absence of
148 typic fusion of late endosomes/vacuoles in a homotypic fusion- and vacuole protein sorting/Vps41-depe
155 or Arl8 (Arf-like GTPase 8) and its effector homotypic fusion/vacuole protein sorting complex (HOPS)
156 axon terminals form two independent sets of homotypic gap junctions, a feature which might be import
157 uggest that an essential interaction between homotypic gD and gH/gL occurs during both HSV-1 and SaHV
158 rom mice cultured on astrocyte islands with "homotypic" glutamatergic or GABAergic pairs and autaptic
160 hocytic activation molecule (SLAM) family of homotypic haematopoietic cell-specific receptors, we det
161 ads to acute illness and results in lifelong homotypic immunity, but individuals remain susceptible t
162 leads to acute illness followed by lifelong homotypic immunity, but susceptibility to infection by t
163 ence consistent with the expected impacts of homotypic immunity, heterotypic immunity, and immune enh
164 m VE-cadherin results in loss of VE-cadherin homotypic interaction and AJ disassembly; however, the s
165 amiana, we define multiple sites of N domain homotypic interaction and infer that it forms a parallel
168 o suppress TNF-induced necrosis, and its RIP homotypic interaction motif (RHIM) domain was required t
169 ix (Z-form) and receptor-interacting protein homotypic interaction motif (RHIM) domains for protein h
170 nifested this function by binding to the RIP homotypic interaction motif (RHIM) domains of TRIF and R
173 ell death pathway requires an N-terminal RIP homotypic interaction motif (RHIM) within R1, acting in
174 ain a motif with some resemblance to the RIP Homotypic Interaction Motif (RHIM), a domain found in ma
175 ase (RIP) 3 (also called RIPK3) mediates RIP homotypic interaction motif (RHIM)-dependent programmed
176 t apoptosis together with competitors of RIP homotypic interaction motif (RHIM)-dependent signal tran
177 activates programmed necrosis through a RIP homotypic interaction motif-dependent association of TRI
179 t contain receptor-interacting protein (RIP) homotypic interaction motifs (RHIM) play a key role in c
181 , located in the SEFIR domain, abolished the homotypic interaction of ACT1 with IL-17 receptors, with
186 separate alpha121 and alpha345 networks by a homotypic interaction through their trimeric noncollagen
188 rt a model in which WRM-1, which can undergo homotypic interaction, binds LIT-1 and thereby generates
190 To define the gH and gL requirements for homotypic interaction, we evaluated the function of a pa
193 connect with prospective glomeruli based on homotypic interactions among neurons expressing the same
194 l tether between the two organelles, forming homotypic interactions and heterocomplexes with its homo
195 smic domain of atlastin acts as a tether and homotypic interactions are timed by GTP binding and hydr
196 previously observed to mediate nectin/nectin homotypic interactions as well as TIGIT/necl-5 recogniti
197 ns initiate intracellular signalling through homotypic interactions between epitopes that are specifi
199 The phenotypes indicate that these promote homotypic interactions between melanophores and xanthoph
200 double-positive thymocytes that provide key homotypic interactions between signaling lymphocyte acti
202 we show that this interaction competes with homotypic interactions between the N termini of differen
203 as adherens junction protein, which through homotypic interactions contributes to the maintenance of
204 overlap with an epitope in D4 that mediates homotypic interactions essential for KIT activation.
207 ogether, our data show that ligand-dependent homotypic interactions in D5 and D7 are essential for VE
212 e effector caspase-1, which interact through homotypic interactions of caspase recruitment domains (C
213 Moreover, these analyses revealed reversible homotypic interactions of NT5B at low pH and in high cal
216 high structural similarity among them, only homotypic interactions participate in complex formation,
217 a transition in the stiffness of E-cadherin homotypic interactions regulates actin and membrane dyna
218 n to enhance binding to host cells, B domain homotypic interactions support cell accumulation and bio
219 ns between pre-amyloid oligomers prevent the homotypic interactions that would lead to mature amyloid
220 ct mediated by receptor biasing toward ErbB3 homotypic interactions uncommonly formed by native neure
221 d neuronal development, ALCAM undergoes both homotypic interactions with other ALCAM molecules and he
222 nimal region in Dab2 that modulates platelet homotypic interactions, all of which provide the foundat
223 1 is the only SYP protein that is capable of homotypic interactions, and is able to interact with bot
224 Our results indicate that Cox15 exhibits homotypic interactions, forming highly stable complexes
229 JAM-B as the major ligand for JAM-C, whereas homotypic JAM-C interactions remained at background leve
230 e 2 exceeded chance levels (P < .05) for all homotypic (median tetrachoric correlation of rho = 0.54
232 eport that autophagosome maturation requires homotypic membrane fusion catalyzed by SNARE proteins.
233 he dynamin superfamily, is known to catalyse homotypic membrane fusion in the smooth endoplasmic reti
236 es nucleotide hydrolysis to the catalysis of homotypic membrane fusion to form a branched endoplasmic
239 protein (GRASP) proteins are Golgi-localized homotypic membrane tethers that organize Golgi stacks in
243 ecific associations for both heterotypic and homotypic motif-pairs with particular haematopoietic cel
244 regulated myeloma cell adhesion, increasing homotypic myeloma cell adhesion while decreasing myeloma
246 rate a role for NKG2D-ligand interaction via homotypic NK cell contact in NK cell effector function.
247 o, that innate immune NK cells can engage in homotypic NK-to-NK cell interactions for optimal surviva
248 atorial complexity of eight linkage types in homotypic (one chain type per polymer) and heterotypic (
249 the issue of whether the PLAD mediates only homotypic or also heterotypic interactions remained inco
258 olfactory bulb mitral cells is an emergent, homotypic property of local networks and sensory informa
260 tions that are created through extracellular homotypic protein-protein interactions between cadherin
261 t replicate by recruitment and conversion of homotypic proteins into growing protein aggregates.
265 g a caspase recruitment domain (ASC) through homotypic PYD-PYD interactions and the assembly of an in
266 ocesses, indicating that both connexins form homotypic rather than heterotypic or heteromeric gap jun
267 EGF and a NRG moiety, can potentially drive homotypic receptor interactions and diminish formation o
268 cell membrane regions and ligand-independent homotypic receptor preassembly, thereby preventing sTNF-
269 is thought to result in lifelong immunity to homotypic reinfection (ie, reinfection with the same ser
272 ored following 5 consecutive days of chronic homotypic restraint stress (CHS), via up-regulating hypo
275 idence is provided for SNAP23 involvement in homotypic SG fusion that occurs in the activated cells.
278 iases while accounting for the phenomenon of homotypic site clustering commonly observed in developme
279 ed immunity was strongest against completely homotypic strains and weakest against fully heterotypic
280 ne effectiveness, comparing effectiveness of homotypic strains with fully or partly heterotypic strai
281 effectiveness was 94% (95% CI 80-98) against homotypic strains, 71% (39-86) against partly heterotypi
282 accine effectiveness was 83% (78-87) against homotypic strains, 82% (70-89) against single-antigen va
284 trocyte subpopulations selectively regulated homotypic synapses through metabotropic glutamate recept
288 derm adhesion through a mechanism other than homotypic trans interactions between the two cell groups
290 rocess, we studied fragment formation during homotypic vacuolar lysosome membrane fusion in Saccharom
293 y that can provide long-term immunity to the homotypic virus and can provide short-term immunity (onl
298 over, the adhesive property occurred in both homotypic with Cx50 expressed in both pairing cells and
299 ecific subtypes pattern mosaics by mediating homotypic (within-subtype) short-range repulsive interac
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