ライフサイエンスコーパス: hope

1 atient is left scared, confused, and without hope.

2 eturns to health investments and undermining hope.

3 espite gloomy forecasts, there is reason for hope.

4 ess effective in all endpoints compared with HOPE.

5 iduals completely unable to feel pain offers hope.

6 NPC-specific immunosuppression may bring new hope.

7 idation of complete networks than originally hoped.

8 oncologist (6 [4.7%] and 5 [3.9%]), loss of hope (3 [2.3%] and 10 [7.8%]), or therapy interference (

9 eated and treated patients, respectively) or HOPE-3 (10.6% and 2.1% of untreated and treated, respect

10 or SPRINT (5.4% untreated, 13.9% treated) or HOPE-3 (13.9% treated, 1.7% untreated).

11 of 120 mm Hg or higher, including SPRINT and HOPE-3 eligibility, and estimated who may have newly req

12 assess the representativeness of SPRINT and HOPE-3 relative to patients in the United States and to

13 h as Heart Outcomes Prevention Evaluation-3 (HOPE-3), did not find consistent benefit.

14 97.3%), "clinician concern about taking away hope" (71.3%), and "unrealistic clinician expectations"

15 The HIV Organ Policy Equity (HOPE) Act now allows transplantation of organs from HIV-

16 Donor families empathized with the initial hope and ultimate despair of potential recipients who mu

17 unt, having low power increases individuals' hope and, in turn, their perceptions of their exchange p

18 For surrogates, a tension existed between hope-based and fact-based expectations.

19 neralized effect on solid organ viability by HOPE before transplantation.

20 particular, seeds from 0.02mM MJ treated Ben Hope black currants exerted contents of gallic, caffeic,

21 ugg(-1) measured in seeds from untreated Ben Hope black currants.

22 vel antimetabolite drug developed at City of Hope Cancer Center, has anticancer activity that stems p

23 apeutic principle that provides a glimmer of hope: cellular postconditioning.

24 Offering hope, early interventions that place institutionalised c

25 In a third group, kidneys were perfused by HOPE for 1 hour after cold storage.

26 The research reviewed provides hope for a complete understanding of, and eventual cure

27 mately 2 years from discontinuation provides hope for a cure for some patients.

28 new physiological mechanisms, promise great hope for a disease that often carries a prognosis worse

29 in psychiatry may not turn into therapeutic hope for affected individuals.

30 many of whom amputation represents the only hope for alleviation of symptoms.

31 T cells are powerful new medicines, offering hope for curative responses in patients with cancer.

32 arch domain criteria (RDoC) matrix offer new hope for determining the neural substrate underlying the

33 These studies provide hope for developing a universal reagent to treat many di

34 well as RAS signaling networks have renewed hope for developing strategies to selectively block hype

35 These findings offer renewed hope for development of IL-12-based treatments for cance

36 e and glucose homeostasis have rekindled the hope for development of novel treatments for obesity and

37 This provides hope for efficient treatment of early obesity-associated

38 h this new understanding has emerged renewed hope for engineering these assembly lines to produce new

39 ing distinct molecular subtypes and offering hope for implementation of targeted therapies.

40 rove progression-free survival, offering new hope for patients suffering from IPF.

41 the cardiovascular field that may offer new hope for patients suffering massive heart attacks.

42 The hope for precision medicine has long been on the drug di

43 with specific DNA repair defects, providing hope for precision treatment of such tumors.

44 antation in the past 5 years provide renewed hope for prevention and treatment of liver graft infecti

45 Stem cell therapy provides immense hope for regenerating the pathological heart, yet has be

46 as metal particles on oxide supports, offers hope for significant bifunctional gains.

47 trolling lipid homeostasis and provide a new hope for the development of small-molecule PCSK9 inhibit

48 these advancements are but an aspiration and hope for the future.

49 und becomes metallic at 180 GPa, fueling the hope for the possible realization of superconductivity a

50 f cancer immunotherapy has generated renewed hope for the treatment of many malignancies by introduci

51 and their differentiated progeny offer great hope for treating disease by providing an unlimited sour

52 ng or non-replicating Mtb may offer our best hope for treatment-shortening combination chemotherapy o

53 idly evolving story of ketamine offers great hope for untangling and treating the biology of both dep

54 tes of greater than 90% the best that can be hoped for is noninferiority trial outcomes compared with

55 e eliminates the barriers, therefore raising hopes for clean/efficient recovery.

56 Patients' hopes for healing were often unrealistic, posing challen

57 pharmacological target ERalpha (ESR1) raised hopes for improved endocrine therapies.

58 f patients with psychotic disorders, raising hopes for more appropriate treatment for these antibody-

59 EVs hold high hopes for novel diagnostic and translational discoveries

60 History encourages caution about our hopes for simplistic answers for presumed "fat drugs" an

61 ately, many patients die on the waiting list hoping for a chance of survival.

62 stitute, SickKids Foundation, and Soccer for Hope Foundation.

63 Here, we aimed to test HOPE in a rodent model of kidney grafts associated with

64 e events by two-to-three weeks, which offers hope in mitigating their catastrophic impact on life, ag

65 e functional genomics of these loci, and the hope is that at least some of these new pathways relevan

66 The hope is that the increase in viral production will lead

67 The hope is that this could accelerate progress toward meeti

68 ding articles could not be included, but the hope is that what follows provides a succinct overview o

69 Our hope is to narrow the gap between the practicing oncolog

70 We hope it is equally useful and interesting to those with

71 his shift is exciting, as we and many others hope it not only will support translation of drug effica

72 As an open source software project, we hope it will attract additions from the community and gr

73 We hope it will now prove useful to many medical sequencing

74 I hope it will still be useful, informative, and enjoyable

75 ome, or all of CLASH is found to be true, we hope it will stimulate future research on the link betwe

76 These discoveries will, it is hoped, lead to further advances in diagnostic classifica

77 e mechanisms of leukaemogenesis and provides hope not only for similar developments in management of

78 ogy are under active investigation and offer hope of adding to the limited available treatment option

79 s to pinpoint new causes of disease with the hope of advancing personalized approaches to the treatme

80 e and its role in atopic conditions with the hope of applying this knowledge to the understanding, pr

81 iscrimination or impoverishment and with the hope of attaining optimal health and social outcomes.

82 elopments in gene and chelation therapy give hope of better prognosis for patients, but successful tr

83 have been investigated in clinical trials in hope of circumventing MDR, with only limited success.

84 HOPE of DCD kidneys was superior to other clinically use

85 are paired with induction regimens with the hope of demonstrating long-term progression-free surviva

86 surface of the virus envelope--thus renewing hope of developing carbohydrate-based HIV vaccines.

87 ng innovative ideas and cannot depend on the hope of developing novel, more powerful technologies.

88 e opportunity to do so in new ways, with the hope of distinguishing between potential explanations fo

89 field of organic electronics thrives on the hope of enabling low-cost, solution-processed electronic

90 eats of the human immune system and our best hope of finally creating an HIV vaccine.

91 nd synthesize ideas on several topics in the hope of providing a coherent picture of and physical ins

92 ation into non-T-cell-inflamed tumors in the hope of rendering them immunotherapy responsive.

93 ith a discussion of future directions in the hope of stimulating additional research in this importan

94 rrently lung transplantation offers the only hope of survival.

95 It is the hope of this committee that this new information will as

96 advances in quantum device fabrication offer hope of utility.

97 oot camp and summer bridge activities in the hopes of better supporting scientific workforce developm

98 al stage matched healthy fertile controls in hopes of better understanding their contribution to the

99 ting the hemagglutinin (HA) stem revitalized hopes of developing a universal influenza vaccine.

100 bundance in giant planets and because of the hopes of discovering high-energy-density materials.

101 In the hopes of improving outcomes, clinicians are increasingly

102 ouse models have been generated, and despite hopes of mimicking human pathology, none displayed profo

103 ses without explicit supportive evidence, in hopes of providing fertile ground for future studies.

104 darabine, melphalan conditioning regimen, in hopes of reducing relapse and decreasing graft rejection

105 f complex illnesses like bipolar disorder in hopes of uncovering the neurobiology of each, as well as

106 For the sake of patients with cancer, we hope one form of precision oncology will deliver on its

107 The study was performed at City of Hope or University of Minnesota with participants comple

108 s for ameliorating the burden of DMD and, we hope, other rare and devastating diseases.

109 We hope others will search EchinoDB to discover datasets re

110 We hope our contribution will help stimulate the mathematic

111 We hope our discussion will generate a greater appreciation

112 cially available filovirus glycoproteins, we hope our experiences with possible difficulties in purif

113 We hope our method can eventually reinforce our understandi

114 We hope our results not only help focus future management a

115 We hope our study will facilitate deeper understanding of t

116 In addition, HOPE-perfused DCD livers achieved similar results as con

117 This said, hope remains high that any of a number of emerging techn

118 HOPE seems to offer important benefits in preserving hig

119 be freely downloaded and used, and will, we hope, serve as an essential resource for this important

120 l A concentrations among couples in Utah-the HOPE study.

121 ojects from our own research group, with the hope that a description of the process, motivations, and

122 We hope that a detailed understanding of the XCMS and MZmin

123 siasm for the cholesterol hypothesis and the hope that additional agents that lower low-density lipop

124 cular mechanisms of charge storage, with the hope that better devices can be rationally designed.

125 in phase 2 and 3 studies, providing immense hope that better treatment will be imminently and widely

126 We hope that by understanding the complex range of effects

127 rties of future devices, giving rise to much hope that carbon electronics operating at high frequenci

128 analysis is an active research area with the hope that cellular process can be deciphered from a sing

129 We hope that CitSci.org will ultimately increase discoverab

130 Two recent reports give hope that CRISPR technology may allow such challenge to

131 his new understanding of cGVHD finally gives hope that effective therapies are imminent for this deva

132 t spares other retinal cells, leading to the hope that expression of light-activated signaling protei

133 The use of such strategies offers hope that for many patients, the next regeneration of th

134 ursued in clinics to treat leukemia with the hope that further breakthroughs in NK cell biology can e

135 By doing this we hope that future studies can better quantify both the be

136 is turned off in melanoma cells, raising the hope that in the future we might be able to turn the swi

137 It is our hope that increased use and awareness of guideline crite

138 This finding fuels hope that inhibition of SARM1 or its downstream componen

139 gkin lymphoma (HL) are remarkable, and raise hope that it may alter the treatment landscape in this d

140 "appropriate-response" perspective, with the hope that it usefully informs future research on and pub

141 We also hope that it will be a call to action for the global tub

142 We hope that it will become an important resource for explo

143 prove control over tumor growth have sparked hope that long-lived control of cancer through stimulati

144 cter as the main deterrent to reflux and the hope that measurement of a low LES pressure would mark t

145 It is our hope that methods such as ours will pave the way for mor

146 n a number of lymphoma subtypes, fueling the hope that MRD detection may soon be applicable in clinic

147 ield of vaccine development and has fostered hope that new ways will be found to combat infectious di

148 des particularly designed to bind to it, and hope that our approach can be used to address some of th

149 Paralleling oncology, we can hope that our treatments will move from nonspecific, lik

150 Finally, we hope that our work also serves as an illustration of the

151 We hope that our work will help accelerate activities in th

152 studies promise even more progress, with the hope that principled targeting of identified thalamic ci

153 Researchers hope that progress in identifying aetiological mechanism

154 We hope that recognition and dissemination of these results

155 We hope that resuscitation councils and other stakeholders

156 taken to improve data validity, raising the hope that robust biomarker tests will become available i

157 the mechanisms of lung fibrosis, and offers hope that similar approaches will transform the manageme

158 We hope that such a cost-effective process can be embraced

159 d other pathogens of Arctic wildlife, in the hope that such models may eventually allow proactive mit

160 We hope that the adapted scheme will help streamline the pr

161 ly in late Phase 1 clinical trials, offering hope that the antifungal armamentarium can be expanded t

162 We hope that the approach described herein will prove usefu

163 hemagglutinin (HA) stalk domain has renewed hope that the development of "universal" influenza virus

164 These regions are then resected with the hope that the individual is rendered seizure free as a c

165 We hope that the issues raised in our article will encourag

166 We hope that the knowledge and material presented here will

167 We hope that the system will serve as a model for other hea

168 We hope that the techniques developed herein may be useful

169 mples of programs that can give us reason to hope that the treatment playing field is being leveled s

170 It is our hope that the use of phenotypic maps such as these will

171 Although there is reason to hope that these discoveries will eventually lead to new

172 There is hope that these efforts will bring a holistic understand

173 f primary biliary cholangitis and PSC in the hope that these new drugs can be used more effectively.

174 We hope that these results will help catalyze improvements

175 It is our hope that these results will shed light on biological in

176 We hope that this (non-exhaustive and subjective) list of p

177 We hope that this analysis assists efforts to ensure this g

178 It is TATFAR's hope that this analysis, combined with other related ana

179 We hope that this conceptual mechanistic framework will sti

180 It is the hope that this could become a real-word application nich

181 We hope that this critical assessment will increase the imp

182 I hope that this description of my journey, with various r

183 We hope that this extensive systematic study will foster fu

184 It is our hope that this review illuminates these apparently contr

185 This is done in the hope that this review may offer guidance in regard to pe

186 We hope that this review will be of great value to boron cl

187 gies that have led to these improvements, we hope that this review will serve as a useful conceptual

188 We hope that this review will serve as an updated introduct

189 By simplifying access to metabolite data, we hope that this system will help enable data sharing and

190 We dare to hope that this tutorial will stimulate new interdiscipli

191 h subject was contributed by experts, and we hope that this will provide a useful resource for newcom

192 We hope that this work will inspire the design of even more

193 standing of influenza virus transmission, we hope that this work will provide a standardized statisti

194 We hope that this, to our knowledge, new approach will be u

195 pes in adult mice is encouraging, and brings hope that with novel therapies, skills and functionality

196 Also, we hope that with this review, we provide a forum and a sta

197 It is hoped that a comprehensive understanding of these mechan

198 It is hoped that a deeper understanding of how these systems c

199 In time, it is hoped that data from ongoing and planned clinical trials

200 It is hoped that future research will lead to more definitive

201 ment patterns and key traveler groups, it is hoped that interventions can be implemented to protect a

202 widely available to all stakeholders, it is hoped that it will enhance therapeutic development pipel

203 on immunotherapy for seed allergy, but it is hoped that such a gap be filled by the development of sa

204 It is hoped that the concepts described here will provide the

205 ng the novel design example presented, it is hoped that the findings will inspire akin designs for ot

206 It is hoped that the molecular mechanisms discussed in this re

207 ave lagged behind those of B-cell ALL, it is hoped that the molecular revolution will enhance our und

208 en primarily genomic medicine, wherein it is hoped that the nucleotide dissimilarities among differen

209 It has been hoped that the recent availability of WHO quantitative s

210 It is hoped that the steady advances in the development of LRA

211 It is hoped that these new models will increase our understand

212 It is hoped that this guidance will assist practitioners and t

213 It is hoped that this model provides a framework for understan

214 It is hoped that this overview will encourage further avenues

215 -related motivational dysfunction, and it is hoped that this research will ultimately lead to improve

216 tic information is also presented, and it is hoped that this review not only provides an account of t

217 It is hoped that this review will lead to a renewed interest i

218 It is hoped that this tabulated summary will provide a useful

219 d dynamics of the HIV-1 Env trimer and renew hopes that a better understanding of Env will translate

220 atedly collected at fixed study sites in the hopes that changes in abundance and productivity may be

221 sensitivity in various tissues, thus raising hopes that electrical activity could be optically mapped

222 can be integrated into research pipelines in hopes that they will be broadly applied in future GWAS a

223 Finally, we hope the recommendations in this report will facilitate

224 We hope the results will provide insights into a better und

225 Furthermore, we hope this facile synthesis strategy can be widely applic

226 We hope this overview will guide TB researchers in the desi

227 Ultimately, we hope this review alleviates some of the confusion surrou

228 Ultimately, we hope this review serves as a useful reference when choos

229 We hope this review will inspire efforts to identify and ex

230 We hope this review will not only help researchers who work

231 We hope this review will not only provide informative knowl

232 We hope this Review will raise awareness to consider the ki

233 and summarizing some guiding principles, we hope this review will stimulate more molecular scientist

234 equires validation before widespread use, we hope this study stimulates further work in refining an A

235 response to gene expression in this way, we hope to achieve more effective and personalized treatmen

236 rstanding of AD and eventually may offer new hope to AD patients.

237 h-dimensional immunofluorescence signals, we hope to advance these data toward mainstream adoption in

238 he support of many people over the years and hope to be able to do the same for others through my men

239 reasons for optimism were a need to maintain hope to benefit the patient (n = 34), a belief that the

240 ding mechanisms, and how, in the process, we hope to create a more efficient and sustainable biomedic

241 We hope to exploit our findings to develop STING-targeted i

242 ns identified from the past 40 years, with a hope to facilitate the research of both basic scientists

243 In the future, we hope to fully characterize steroid receptor-specific fun

244 With respect to these results, we hope to give a strong impulse for further investigation

245 y and studying their molecular functions, we hope to help the interpretation of GWAS results and prov

246 Collectively, we hope to highlight the power of aryne chemistry to access

247 Proponents of this approach hope to improve not only short-term survival, but also p

248 Gene therapy (GT) has offered immense hope to individuals who are visually impaired because of

249 We hope to inspire the fabrication of these cascaded logic

250 We hope to make the community more aware of these powerful

251 However, if we hope to meet the needs of patients within our changing h

252 his secondary mutation into Candid#1 GPC, we hope to minimize the likelihood of reversion and enhance

253 mal preoperative coagulation tests, with the hope to mitigate bleeding complications.

254 By characterizing such correlations one may hope to obtain information regarding functionally-releva

255 We hope to offer chemists the tools to have a good grasp of

256 With further study, we hope to offer these patients more individualized patient

257 rin and its derivatives provide a glimmering hope to peek into the world of antiaromatic systems.

258 rigorous entomological baseline that we can hope to project future health impacts of these viruses.

259 With this I hope to promote the diversity of OMO-based projects that

260 In this review, we hope to provide a brief overview of the important genera

261 sive review of PRRT2-associated diseases, we hope to provide a scientific resource for informing futu

262 isting regulatory and developmental gaps, we hope to provide a sense of where focusing resources may

263 We hope to provide an understanding of the human-protozoal

264 In highlighting existing deficiencies, we hope to provide direction for future research that will

265 We hope to raise awareness that the cell biology of miRNAs

266 Ultimately, the best hope to reduce the disease burden is with broadly protec

267 logy for communicating outcomes, these tools hope to reduce the influence of subjective judgment of s

268 ied to identify gaps where they exist in the hope to spur further activity in this very important res

269 In presenting these, we hope to stimulate further debate and action towards impr

270 que property combinations and in doing so we hope to stimulate further research and yet more innovati

271 By opening up this discussion, we hope to stimulate future debates on co-production as wel

272 al antibodies currently in development offer hope to those individuals suffering from the disease by

273 boration and harmonization is required if we hope to transition from empiric selection of therapeutic

274 ast 20 years and the clinical questions they hoped to address.

275 dopsis with typical QTP distribution, and is hoped to be a new model system to study speciation and e

276 iology underlying pediatric gliomas, fueling hopes to achieve both goals.

277 ical systems, both in cells and in vivo, and hopes to communicate to readers the diversity of applica

278 This review hopes to describe the projection-specific intrinsic char

279 ement and accompanying recommendations, ASCO hopes to increase awareness of the tremendous global imp

280 rary using the central domain of ubiquilin-2 hoping to identify proteins whose binding is affected by

281 elopment can greatly aid academic scientists hoping to partner with pharmaceutical companies.

282 erosclerotic plaque in patients for decades, hoping to prevent acute coronary events.

283 HOPE-treated DCD kidneys showed dramatically better func

284 ic cholangiopathy or nonfunction occurred in HOPE-treated livers, whereas 18% of unperfused DCD liver

285 HOPE treatment of DCD livers significantly decreased gra

286 approach, hypothermic oxygenated perfusion (HOPE), used for DCD liver grafts, is based on cold perfu

287 The effect of HOPE was dependent on perfusate oxygenation in the cold.

288 Their hope was that a similar progression of medical understan

289 mising avenues for future research, which we hope will bring us closer to an integrated understanding

290 ics at the "bio-nanosheet" interface that we hope will enable safe and successful development of tech

291 dge, we outline a pragmatic approach that we hope will enhance clinical management in this area.

292 endations for experimental protocols that we hope will increase the chance that future experiments ca

293 e applications from different fields that we hope will inspire new users to adopt 2D-LC for their ana

294 s and cognitive-functional linguists that we hope will spark the cross-disciplinary discussion necess

295 ound the world and provides evidence that we hope will spur the development of detailed guidelines on

296 In this article, we offer guidelines that we hope will steer researchers toward best practices for th

297 t step for this latter population, and it is hoped will allow for more efficient combinations with no

298 This, we hope, will shed greater light on the potential mechanism

299 glass compositions via blending raises much hope with the potential to provide new glasses with new

300 ut their disease prognosis and corresponding hopes, worries, and goals.