ライフサイエンスコーパス: host defence

1 gen infection and for establishing effective host defence.

2 iew of the immune system and its function in host defence.

3 ptides (AMPs) and other mechanisms of innate host defence.

4 oteases in the interaction with human innate host defence.

5 ruses, appears to have adapted to evade this host defence.

6 I interferons and other genes important for host defence.

7 of epithelial-derived defensins in mammalian host defence.

8 rial products in this region is critical for host defence.

9 ce for the importance of natural products in host defence.

10 SNOs) are central to signal transduction and host defence.

11 has revealed new and important insights into host defence.

12 ral to both innate and adaptive immunity for host defence.

13 portant role in allowing B. cepacia to evade host defence.

14 lineages are recognised; each has a role in host defence.

15 direct and indirect effects on pathogens and host defence.

16 potent regulator of the cellular response in host defence.

17 at they have an important underlying role in host defence.

18 portals of bacterial entry, are important to host defence.

19 ncluding cell proliferation, development and host defence.

20 innate immunity that plays pivotal roles in host defence.

21 24 h, p=0.0032) without being detrimental to host defence.

22 pneumococcal pneumonia without compromising host defence.

23 uently validate for their role in antifungal host defence.

24 analysis has suggested their involvement in host defence.

25 22 and IL-23 are able to restore the mucosal host defence.

26 in the pathogenesis of atopic dermatitis and host defence.

27 ways that are directly relevant to the human host defence.

28 umoniae infection, HVEM is also required for host defence.

29 of microbes, whether to promote mutualism or host defence.

30 sting that extrusion of NETs is important in host defence.

31 t targeting HVEM with agonists could improve host defence.

32 ns in nutrient availability as well as plant host defences.

33 he importance of this system for survival to host defences.

34 creted protein may protect the parasite from host defences.

35 microbial virulence apparently by modulating host defences.

36 g Salmonella against oxygen radical-mediated host defences.

37 organisms to resist antimicrobial drugs and host defences.

38 lymeric protein hydrogel for protection from host defences.

39 ing in strong selection for the evolution of host defences.

40 exploit cognitive and sensory limitations in host defences.

41 properties to facilitate persistence despite host defences.

42 virulence factor which functions to subvert host defences.

43 s to the ability of the spirochaete to evade host defences.

44 er the cytoplasm of plant cells and suppress host defences.

45 lasia in the intestinal mucosa, and elevated host-defence ability against an intestinal bacterial pat

46 the amino sugars as a harbinger of potential host defence activation, and suppresses the expression o

47 ding protein (LBP), which are central to the host defence against bacteria, and cholesteryl ester tra

48 OS) produced by phagocytes are essential for host defence against bacterial and fungal infections.

49 lergic and autoimmune disorders, and optimal host defence against bacterial and parasitic infections

50 We investigated the role of mast cells in host defence against bacterial infections using a well c

51 s (AMPs) represent a key component of innate host defence against bacterial pathogens.

52 studies indicate that STING is essential for host defence against DNA pathogens such as HSV-1 and fac

53 acute peritonitis that is indispensable for host defence against early systemic bacterial spread and

54 rophage mannose receptor is not essential to host defence against fungal pathogens, as previously tho

55 lls best known for their role in allergy and host defence against helminth parasites.

56 The host defence against helminths such as Nippostrongylus b

57 led pro- and anti-inflammatory responses for host defence against infection and disease states.

58 ndicate that one of the functions of IL-3 in host defence against infection is to expand populations

59 ation by macrophages is an essential part of host defence against infection.

60 ant protein (SP)-A and SP-D, are involved in host defence against infectious and allergenic agents vi

61 cyte-derived intestinal MPs in ILC3-mediated host defence against intestinal infection.

62 h1 response, which is critical for effective host defence against intracellular pathogens.

63 ropriate inflammatory responses critical for host defence against invading pathogens or tumours.

64 Th2 immunity is a primary host defence against metazoan pathogens and two of the i

65 ogen species (RNS) play an essential role in host defence against Mycobacterium tuberculosis (MTB) in

66 t allergic immunity has an important role in host defence against noxious environmental substances, i

67 reveals the critical importance of LUBAC in host defence against pathogens.

68 that T(H)17 cells have an important role in host defence against specific pathogens and are potent i

69 lymphocytes are believed to be important in host defence against the human immunodeficiency virus (H

70 distinct effector functions best suited for host defence against the invading pathogen.

71 conserved T-cell receptor and contribute to host defence against various microbial pathogens.

72 duction of cytokines, which are important in host defence against virus infections to both RSV and rh

73 change in community composition might affect host defences against Bd.

74 While theoretical models on the evolution of host defences against disease have been widely studied,

75 ne response that are normally concerned with host defences against infection can, under some circumst

76 on immune cells, which also plays a role in host defences against infection.

77 present useful targets in the modulation of host defences against viral pathogens.

78 CD4(+) T cells are critical for host defence and autoimmunity.

79 terleukin (IL)-17 (T(H)17), are critical for host defence and autoimmunity.

80 challenges of the infectious process such as host defence and bacterial products.

81 protein interaction networks are integral to host defence and immune signalling pathways, which are o

82 ctions, and suggest a potential role in both host defence and immunopathology.

83 and IL-17, might have essential functions in host defence and in the pathogenesis of autoimmune disea

84 scavenger receptors play important roles in host defence and in the regulation of acquired immunity.

85 Our results show that p38 may influence host defence and inflammation by maintaining the balance

86 and CD4+ T cells plays an important role in host defence and mucosal homeostasis, thus it is importa

87 ation of eosinophils, which are important in host defence and the pathogenesis of allergies and asthm

88 Innate lymphoid cells (ILCs) contribute to host defence and tissue repair but can induce immunopath

89 charide that also confers resistance to many host defences and antibiotic treatments.

90 his pattern likely resulted from both weaker host defences and greater adaptation by parasites to inf

91 ensive polysaccharide capsule, which impedes host defences and is absolutely required for fungal viru

92 he ModA2 phasevarion in adaptation to innate host defences and reveal an additional microenvironmenta

93 er of virulence genes required to circumvent host defences and/or acquire nutrients in the host.

94 s, bacterial parasites cooperate to overcome host defences, animals breed cooperatively, and humans a

95 ted with roles in reproduction, immunity and host defence appear to be under diversifying positive se

96 Host defences are often accompanied by programmed cell d

97 t that coordinates inflammatory responses in host defence but is pathogenic in autoimmunity.

98 (RNS) function as powerful antimicrobials in host defence, but so far little is known about their bac

99 gene product in plant-microbe interaction or host defence, but the fact that all the transcripts were

100 nocytes play a crucial role in antimicrobial host defence, but the mechanisms by which they protect t

101 ate immune system is absolutely required for host defence, but, uncontrolled, it leads to inflammator

102 eukaryotic counterparts, TtAgo functions in host defence by DNA-guided DNA interference.

103 st-growing intracellular Salmonella overcome host defence by reprogramming macrophage polarization.

104 dapt to diverse environments and/or to evade host defences by antigenic variation.

105 hat potentially allows the organism to evade host defences by antigenic variation.

106 , adrenaline may also serve in favour of the host defences by lowering antimicrobial peptide resistan

107 ptors, advances in chemotaxis, subversion of host defences by pathogens, adaptation to high salt, com

108 Staphylococcus aureus subverts host defences by producing a collection of virulence fac

109 factor is an adenylate cyclase that impairs host defences by raising cellular cAMP levels.

110 at the antimicrobial conditions generated by host defences can accelerate the generation of genome re

111 n that gingival bleeding and infiltration of host defence cells are symptoms of periodontal infection

112 Whereas acute inflammation is critical for host defence, chronic inflammation contributes to tumori

113 plants as responsible for detoxification of host defence compound 2-benzoxazolinone.

114 vading pathogens and for initiating cellular host defence countermeasures, which include the producti

115 These results directly link the initial host defence defect to the loss of CFTR, an anion channe

116 For example, the herbicide atrazine affects host defences (e.g. resistance and tolerance) of the amp

117 include proteins which function to modulate host defences either through proteolysis, post-translati

118 pecificity correlated with their response to host defences: escalating traits largely affected genera

119 w ecological feedbacks generate diversity in host defence focussing on when polymorphism can evolve w

120 This defect in host defence has generally been ascribed to the immaturi

121 loss of CFTR function first disrupts airway host defence has remained uncertain.

122 are an important native component of innate host defence in mice and provide protection against necr

123 undant function, and is required for mucosal host defence in the lung.

124 ntimicrobial peptide important in epithelial host defence in the small intestine.

125 s well as improved strategies for augmenting host defence in this vulnerable population.

126 Human pathogenic Yersinia resist host defences, in part through the expression and delive

127 r 17 (TH17) cells are critically involved in host defence, inflammation, and autoimmunity.

128 e essential function of the immune system in host defence is best illustrated when it goes wrong; und

129 The requirement for FADD in mammalian host defence is evocative of innate immune signalling in

130 notion that humoral immunity contributes to host defence is unproven.

131 Dendritic cells serve a key function in host defence, linking innate detection of microbes to ac

132 ndent necrotic pathway that has emerged as a host defence mechanism against murine cytomegalovirus.

133 urst, effectively masking the impact of this host defence mechanism.

134 Therefore, as a part of the host-defence mechanism, the mucus could also be responsi

135 tions in pathogenesis by blocking non-immune host defence mechanisms and acting as a relatively non-i

136 cause biofilms notoriously resist killing by host defence mechanisms and antibiotics.

137 o the ability of M. tuberculosis to overcome host defence mechanisms and grow in a mammalian host.

138 several orders of magnitude lower, and their host defence mechanisms are substantially more effective

139 Since host defence mechanisms can be costly, individual hosts

140 erated a strategy to efficiently escape from host defence mechanisms during reactivation from latency

141 ons of years, during which time a variety of host defence mechanisms has evolved.

142 Understanding of anti-candida host defence mechanisms in the vagina has developed slow

143 actors at its disposal) and the integrity of host defence mechanisms.

144 llularly, thereby helping the virus to avoid host defence mechanisms.

145 lps the bacilli to overcome the onslaught of host defence mechanisms.

146 which are necessary to avoid or overcome the host defence mechanisms.

147 Nitric oxide (NO) is an important host defence molecule that varies its immune stimulatory

148 gress in understanding the function of these host defence molecules in intestinal physiology.

149 growing evidence that microbes contribute to host defences of plants and animals.

150 The effect of elicitors associated with host defence on betacyanin accumulation in Amaranthus ma

151 e conserved structures that also function in host defence, pain, organ protection and tissue remodell

152 ted that Par37 displays characteristics of a host defence peptide.

153 increase (P < 0.05) in the production of the host-defence peptide (HDP), BD2.

154 Host defence peptides (HDPs) are critical components of

155 esist or tolerate a variety of antimicrobial host defence peptides and proteins.

156 The identification of the host defence peptides as target effectors in the innate

157 hat of the active sub-units of, for example, host-defence peptides and p53.

158 innate immune receptors cooperate to mediate host defence: phagocytic receptors, such as the mannose

159 g with a variety of proteins affiliated with host defence, programmed cell death and innate immunity

160 ance to the antibacterial effects of a human host defence protein.

161 rring susceptibility to this major pulmonary host defence protein.

162 tify human neutrophil elastase (NE) as a key host defence protein: NE degrades Shigella virulence fac

163 n to identify protein complexes that contain host defence proteins and pathogenicity factors.

164 ogen-derived effector and are perceived by a host defence receptor.

165 t is perceived via direct interaction with a host defence receptor.

166 Angiogenins are a family of host defence-related ribonucleases, of which at least on

167 of Udorn does not (effectively) inhibit this host defence response in human monocytes.

168 cells of the innate immune system to mount a host defence response to infection, they must recognize

169 d in clearance of ROS, thus anticipating the host defence response.

170 cant side effects such as suppression of the host defence response.

171 ate hosts, trematode parasites down regulate host defence responses by interfering with key signal-tr

172 y the fungus, and for the rapid induction of host defence responses in an incompatible reaction.

173 associated molecular products, TLRs activate host defence responses through their intracellular signa

174 Interleukin (IL)-1 is a mediator of host defence responses to inflammation and injury, inclu

175 IL-1 mediates host defence responses to local and systemic disease and

176 TLRs can directly induce innate host defence responses, but the mechanisms of TLR-mediat

177 mst12 mutant also failed to elicit localized host defence responses, including papilla formation and

178 en linked to the activation of intracellular host defence signalling pathways.

179 ful drivers of both the strength and type of host defence strategies against parasites.

180 of the ecology and evolution of alternative host defence strategies.

181 , the evolutionary history of this DNA-based host defence strategy is unclear.

182 role in resistance to non-oxidative mucosal host defences such as anti-microbial peptides.

183 ruses express proteins to evade non-specific host defences such as complement, interferons and the in

184 rane decoration may enable them to evade the host defence system and colonize the subgingival space.

185 ucociliary clearance (MCC) is a major airway host defence system that is impaired in patients with sm

186 While these stresses serve as part of a host defence system, V. cholerae has evolved resistance

187 e been implicated in pathogen evasion of the host defence system.

188 crease in Paneth-cell-mediated antimicrobial host defence that compromised dendritic cell recruitment

189 ults reveal a critical role for cryopyrin in host defence through bacterial RNA-mediated activation o

190 or (OF) is an adenylate cyclase that impairs host defences through a variety of mechanisms including

191 Bacterial pathogens must suppress host defences to cause disease.

192 al nitrooxidative stress response suppresses host defences to facilitate the growth and development o

193 clearly establish that MCs may contribute to host defences to Leishmania in a differential manner, by

194 Host defences to microorganisms rely on a coordinated in

195 for DNA-PK, a finding with implications for host defence, vaccine development and autoimmunity.DOI:h

196 nd host, leading to the intricate balance of host defence versus parasite survival.

197 en as an adaptation of the parasite to evade host defence: we show that the coordination necessary fo

198 ue characteristics involved in circumventing host defences, which significantly contribute to their v