ライフサイエンスコーパス: housekeeping

1 d in 18% of participants, most commonly with housekeeping (48%) and transportation (36%) and least co

2 ases containing the a3-subunit, but not the "housekeeping" a1-subunit, were isolated bound to actin.

3 nput differentiates proton signaling from pH housekeeping activity.

4 ductase (GR), thereby supporting fundamental housekeeping and antioxidant pathways.

5 100 000 person-years [95% CI 593-809]), and housekeeping and factory workers.

6 We compared the pulsing of five housekeeping and five developmentally induced genes by d

7 Macroautophagy serves cellular housekeeping and metabolic functions through delivery of

8 Sensory-motor and motor circuits have both housekeeping and modulatory functions, implemented in th

9 ts and thus plays critical roles in cellular housekeeping and nutrient recycling.

10 to increase exposure to PBDEs and that good housekeeping and personal hygiene practices may reduce e

11 using two independent reporters representing housekeeping and photosynthetic pre-proteins.

12 riches for context-specific transcripts over housekeeping and/or structural RNA, and it preserves the

13 ribed and silent genes, repetitive elements, housekeeping, and tissue-specific genes.

14 the stress-directed SAGA complex versus the housekeeping assembly factor TFIID.

15 o generate catabolites that are required for housekeeping biosynthesis processes.

16 thway which plays a crucial role in cellular housekeeping by internalization, transport, sorting and

17 first time that AGGF1 activates autophagy, a housekeeping catabolic cellular process, in endothelial

18 This study shows that KatG is the major housekeeping catalase of DC3000 and provides protection

19 ology categories were overrepresented, while housekeeping cellular functions were mainly transcriptio

20 genome and involved in regulation of either housekeeping/cellular maintenance genes or liver-specifi

21 Here we show that calreticulin, a housekeeping chaperone commonly expressed in most eukary

22 iability and likely functions as the general housekeeping chaperonin, GroEL1 is dispensable, but its

23 in contrast to those metabolites exhibiting housekeeping characteristics?

24 indicates that such recruitment of cellular housekeeping components is a common feature used to inte

25 lular localization relative to the ancestral housekeeping desaturase may have allowed proto-SAD5's re

26 ansport, and mutations in the ubiquitous and housekeeping dynamin 2 (DNM2) have been associated with

27 endosomal membranes, thereby regulating the housekeeping endocytic transport in eukaryotes.

28 Their turnover requires the housekeeping endonuclease RNase E and is activated by th

29 that interact with different core promoters: housekeeping enhancers (hkCP) and developmental enhancer

30 In cells transfected with an siRNA for the housekeeping enzyme glyceraldehyde-3-phosphate dehydroge

31 study can act as a model whereby a universal housekeeping enzyme may be adapted to act also as a key

32 Deletion of the gene coding the housekeeping enzyme sortase A led to the release of NudP

33 In Salmonella enterica, CobA is the housekeeping enzyme that is required for de novo AdoCbl

34 ndings suggest that rather than serving as a housekeeping enzyme, MS has a broad and dynamic role in

35 hosphatase 1 (dCTPase) is a nucleotide pool "housekeeping" enzyme responsible for the catabolism of c

36 Aminoacyl-tRNA synthetases (aaRSs) are housekeeping enzymes essential for protein synthesis.

37 ption that they are largely constitutive and housekeeping enzymes.

38 MTH1 is one of the "housekeeping" enzymes that are responsible for hydrolyzi

39 While the essential SecA1 handles "housekeeping" export, the nonessential SecA2 exports a s

40 binding protein profilin is believed to be a housekeeping factor that maintains a general pool of una

41 allows for a reversible sigma-switching from housekeeping factors to alternate sigma-factors when the

42 However, housekeeping forms of clathrin-mediated endocytosis were

43 6S RNAs function through interaction with housekeeping forms of RNA polymerase holoenzyme (Esigma(

44 all RNA that binds within the active site of housekeeping forms of RNA polymerases (e.g. Esigma(70) i

45 BDE-153 was associated with higher housekeeping frequency (35.9%[0.4, 83.9%]) and BDE-209 w

46 In conclusion, seafood consumption, higher housekeeping frequency, and foam mattress were associate

47 curtains and carpets at home, mattress type, housekeeping frequency, and television use was also coll

48 r whether defects in this well characterized housekeeping function cause the specific degeneration of

49 degradation of mitochondria, is an important housekeeping function in eukaryotic cells, and defects i

50 ants and mammals and serves a general genome housekeeping function in plants.

51 GTP dysregulation occurs, revealing a vital housekeeping function of (p)ppGpp; in fact, loss of (p)p

52 books depict metabolism as a well understood housekeeping function of cells.

53 fferocytosis is recognized as a constitutive housekeeping function of macrophages, these data indicat

54 VAPs have an intracellular housekeeping function, as well as an extracellular signa

55 Thus, rather than serving a general housekeeping function, our data suggest that PMCA1a is a

56 uted, and is thus widely believed to play a "housekeeping" function in mammalian cells.

57 tious disease, but also are involved in host housekeeping functions and can suppress allergic disease

58 Proteins with housekeeping functions and stable expression level such

59 netic states across cell types correspond to housekeeping functions and stimulus response, respective

60 t nonhost resistance mechanisms and pathogen housekeeping functions are conserved at deeper phylogene

61 nly been assigned stress response and normal housekeeping functions but also have a role in certain h

62 that have been thought primarily to subserve housekeeping functions in cells-ribosomal RNAs, transfer

63 but instead are often involved in essential housekeeping functions that are highly conserved across

64 veal that NF-Y regulates not only genes with housekeeping functions through cell type-invariant promo

65 525 orthologs that generally associated with housekeeping functions), or specific to each genome (>20

66 in signaling processes and avoid genes with housekeeping functions, and that miRNAs orchestrate temp

67 They are involved in housekeeping functions, metabolism (sugar, amino acids),

68 t protein homologues; instead, they affected housekeeping functions, such as signal recognition parti

69 We show that although FAS possesses housekeeping functions, under starvation conditions it i

70 al binding events are enriched at genes with housekeeping functions, while distal binding events inte

71 tified of which class A sortase is meant for housekeeping functions.

72 ed to nucleotide biosynthesis and a range of housekeeping functions.

73 r suited than stochastic switch behavior for housekeeping functions.

74 KAR2 under stress had no effect on its known housekeeping functions.

75 rmal tissues, which were highly enriched for housekeeping functions.

76 ble elements and structural genes for normal housekeeping functions.

77 drives their selection and whether they have housekeeping functions.

78 while also performing important homeostatic housekeeping functions.

79 fficient translation of genes with important housekeeping functions.

80 ates the translation of genes with important housekeeping functions.

81 s rendering them unable to perform important housekeeping functions.

82 t plants, features consistent with essential housekeeping functions.

83 men was determined by quantitating the human housekeeping GAPDH gene.

84 g copies) and RNA transcripts from the GAPDH housekeeping gene (5.45 ng total mouse embryonic stem ce

85 there was no amplification of CRX; only the housekeeping gene (GAPDH) demonstrated amplification.

86 nching holes to deliver cholesterol-modified housekeeping gene (Gapdh) siRNA to the mouse ear skin.

87 Among children positive for the P falciparum housekeeping gene (PF08_0085; ubiquitin-conjugating enzy

88 est, as indicated by local expression of the housekeeping gene acpP and by expression from a constitu

89 tissue-specific transcriptional control of a housekeeping gene by a generic TF.

90 from 69 of the 74 FFPE tissues from which a housekeeping gene could be amplified and was also cost-e

91 ute and temporal control of the prototypical housekeeping gene encoding the proliferating cell nuclea

92 xpression domains in C(3), including typical housekeeping gene expression patterns in various tissues

93 We identified SNORD44 as a suitable housekeeping gene for qPCR analysis comparing normal and

94 which dominantly inherited mutations in the housekeeping gene GARS, which encodes glycyl-tRNA synthe

95 tases were quantified by measuring the human housekeeping gene hHPRT in livers.

96 These results indicate that the housekeeping gene HPRT regulates purinergic signaling in

97 nant of Polycomb recruitment to the CGI of a housekeeping gene in somatic cells.

98 The role of this metabolic housekeeping gene in tumorigenesis is still a matter of

99 t locations within a BAC containing the DHFR housekeeping gene locus, we obtain copy-number-dependent

100 on (calculated for each kit as the number of housekeeping gene PCR-positive samples divided by the to

101 CR-positive samples divided by the number of housekeeping gene PCR-positive samples) were 58 to 93%.

102 ase/autocrine motility factor (PGI/AMF) is a housekeeping gene product/cytokine that catalyzes a step

103 intersubspecies lateral gene transfer of the housekeeping gene recA, which has not previously been re

104 phylogenetic analyses of vacA sequences and housekeeping gene sequences indicate that vacA does not

105 ed and identified to the species level using housekeeping gene sequencing.

106 We applied ScanDel to HPRT1, the housekeeping gene underlying Lesch-Nyhan syndrome, an X-

107 through retroposition of a highly conserved housekeeping gene, Caf40.

108 the core promoter -270GC-rich box of PIGM, a housekeeping gene, disrupts binding of the generic trans

109 -function mutations in the widely expressed, housekeeping gene, GARS The mechanisms underlying select

110 e compared to that of beta2 microglobulin, a housekeeping gene.

111 robust upregulation of this highly expressed housekeeping gene.

112 s suggest a surprising potential role for a 'housekeeping' gene in fine-tuning the development of an

113 y after photobleaching implied modulation of housekeeping-gene pulse strength occurs at the level of

114 free CpG island from the human HNRPA2B1-CBX3 housekeeping genes (A2UCOE) effectively prevents transge

115 ly 25% of expressed genes that are essential/housekeeping genes (e.g. RNA synthesis and splicing).

116 Housekeeping genes (HKG) are presumed to be constitutive

117 Housekeeping genes (HKGs) are essential for basic mainte

118 Selection of optimal housekeeping genes (HKGs) as reference genes is critical

119 is dependent on normalization by appropriate housekeeping genes (HKGs).

120 as developed based on the sequences of eight housekeeping genes (ppa, pgm, gyrB, gmk, glyA, atpA, arc

121 ic proteins, but also repress a small set of housekeeping genes - such as those encoding lactate dehy

122 displays binary behavior, strongly expressed housekeeping genes altered the magnitude of their transc

123 ysis of 1930 pneumococcal genotypes from six housekeeping genes and 94 genotypes from related species

124 erol (gpd1) caused a prolonged repression of housekeeping genes and a delay in gene activation at ind

125 those of four major gastric proteins and two housekeeping genes and comparable to the level of pepsin

126 proteins do not include proteins encoded by housekeeping genes and instead include ABC transporters

127 an expanded eight gene version based on six housekeeping genes and two 'putative virulence' genes (e

128 , our analysis reveals that the locations of housekeeping genes are closely associated with cross-tis

129 ly bipartite organization in which conserved housekeeping genes are concentrated in syntenic gene-ric

130 We previously reported that specialized and housekeeping genes are differentially regulated via de n

131 ed during terminal erythroid maturation, but housekeeping genes are not preferentially lost.

132 By using housekeeping genes as a model, we demonstrated that XP-D

133 th been shown to be suitable alternatives to housekeeping genes as loading controls.

134 s-related genes, and are reduced to encoding housekeeping genes as well as a protease subunit (clpP)-

135 ulation of a large number of genes including housekeeping genes as well as actively regulated genes.

136 When normalized with respect to the housekeeping genes B2M or GAPDH, mean tumor/normal ratio

137 spect to tissue weight or mRNA levels of the housekeeping genes B2M or GAPDH, were over-expressed in

138 parison to normalization with respect to the housekeeping genes B2M or GAPDH.

139 ate tissue-specific, co-regulated as well as housekeeping genes based only on their initial proximity

140 ve to either: tissue weight or levels of the housekeeping genes beta-2 microglobulin (B2M) and glycer

141 a set of randomly chosen genes, and a set of housekeeping genes broadly conserved in eukaryotes.

142 As loss of neighbouring housekeeping genes can confer collateral lethality, we s

143 nes, and multilocus sequence typing of three housekeeping genes confirmed culture purity.

144 e groEL gene, and multilocus sequencing of 7 housekeeping genes confirmed the presence of a common st

145 phylogenetically distinct clusters, whereas housekeeping genes do not, consistent with a recent spre

146 IB dynamics that regulate specialized versus housekeeping genes during cardiac hypertrophy.

147 promoter regions of some of the most active housekeeping genes during interphase in human cells, but

148 rom positive controls, negative controls and housekeeping genes embedded in the nCounter system.

149 e, in wild-type virus-infected cells mRNA of housekeeping genes exemplified by GAPDH is degraded rapi

150 ely removes highly expressed but nonspecific housekeeping genes from lens tissue expression profiles,

151 such GAPs generated so far bear mutations in housekeeping genes important for parasite development in

152 y be used for other types of therapeutic and housekeeping genes in endogenous and exogenous stem cell

153 alterations of Creb, ubiquitin-C, and other housekeeping genes in PS-deficient MEFs, indicating tran

154 interacts with transcriptional regulators at housekeeping genes in somatic cells is not well understo

155 or, to mechanistically dissect how essential housekeeping genes like TFR1 successfully balance the op

156 erentially hypermethylated, whereas those of housekeeping genes remain hypomethylated.

157 In this study, expression profiles of 16 housekeeping genes selected from C. maculata were cloned

158 ots typically involves normalization against housekeeping genes such as beta-actin.

159 rase III is highly conserved and transcribes housekeeping genes such as ribosomal 5S rRNA, tRNA and o

160 red as selfish genes, outnumber essential or housekeeping genes suggests that they offer selective ad

161 +)CD8(+) stage involved a global shutdown of housekeeping genes that is rare among cells of the immun

162 In contrast, housekeeping genes that lack pronounced Pol II pausing s

163 by a process that may be common among other housekeeping genes that reside in large regulatory domai

164 is brings about global repression and allows housekeeping genes to be expressed in all cells of the b

165 hout prior knowledge of or assumptions about housekeeping genes to normalize microarrays that are qui

166 After in silico analysis, a final set of 7 housekeeping genes was selected (dnaA, metS, recA, tufA,

167 bolic functions, while mRNA levels for these housekeeping genes were low in cells at the bottom of th

168 says were used to detect fungal DNA, and two housekeeping genes were used to assess the presence of a

169 Four housekeeping genes with allelic polymorphisms were ident

170 ilocus sequence types (ST(M); based on seven housekeeping genes) and four groups of clonally linked (

171 thermore, we present 692 uniformly expressed housekeeping genes, 43% of whose human orthologs are als

172 omains of early embryonic development genes, housekeeping genes, and constitutive regulatory elements

173 usually differ for gene density, GC content, housekeeping genes, and recombination frequency.

174 th polymorphisms at multiple loci (rrn, vcg, housekeeping genes, and repetitive DNA) designated profi

175 and IB), atpD (type II), and recA (type III) housekeeping genes, as well as a Fic family toxin gene (

176 11 H. ducreyi loci, including virulence and housekeeping genes, augmenting published data sets with

177 levels affect the polyadenylation levels of housekeeping genes, but not of p21 and c-fos genes, whic

178 leotide polymorphism (SNP) approach for nine housekeeping genes, characterizing penA alleles, and ant

179 scheme, based on conserved regions of seven housekeeping genes, gltA, gdhB, recA, cpn60, rpoD, gyrB,

180 valuate the suitability of two commonly used housekeeping genes, glyceraldehyde 3-phosphate dehydroge

181 iption start site on many of the most active housekeeping genes, including genes encoding translation

182 e to convergent losses of photosynthesis and housekeeping genes, making them excellent systems for st

183 II plays a role in incrementally increasing housekeeping genes, proportionate to the increase in hea

184 s, especially to conserved regions of common housekeeping genes, such as actin, alpha/beta-tubulin, a

185 MLST) scheme, comprised of seven single-copy housekeeping genes, to genetically characterize Trichomo

186 ched for the insulator binding protein CTCF, housekeeping genes, transfer RNAs and short interspersed

187 ion partners of functional fusions are often housekeeping genes, whereas the 3' fusion partners are e

188 genes, 43% of whose human orthologs are also housekeeping genes.

189 els of promoter SNP density are common among housekeeping genes.

190 contain both spliced and unspliced mRNAs of housekeeping genes.

191 affect expression or polymerase occupancy at housekeeping genes.

192 ription in many pathogens; they also control housekeeping genes.

193 ng scheme (MLST) for P. acnes based on seven housekeeping genes.

194 interspersed Tcrd elements and neighbouring housekeeping genes.

195 und in the body of some actively transcribed housekeeping genes.

196 and relies on the sequencing of one or more housekeeping genes.

197 ning regions of gyrA and parC, two essential housekeeping genes.

198 obile genetic elements and also mutations in housekeeping genes.

199 identified as outliers, historic markers, or housekeeping genes.

200 biogenesis and function as well as for many housekeeping genes.

201 ultilocus sequence typing based on bacterial housekeeping genes.

202 ylogeny based on partial sequencing of seven housekeeping genes.

203 RNA (mRNA) expression via GAPDH or 18S rRNA housekeeping genes.

204 of messenger RNAs were normalized with six "housekeeping" genes and a reference RNA.

205 We found that the repression of "housekeeping" genes coincides with the transient activat

206 m mutations in a family of general "cellular housekeeping" genes is unknown.

207 The four 'housekeeping' genes tested were expressed in purified is

208 ve chromatin and constitutively transcribed (housekeeping) genes.

209 ys are spatially proximal to one another and housekeeping-genes tend to be proximal to several other

210 for at least one daily-living activity, with housekeeping, grocery shopping, and laundry being the ac

211 We find that sets of housekeeping interactions provide a sensitive means of e

212 operon, which encodes an alternative to the housekeeping Isc iron-sulphur cluster assembly system.

213 ichia coli, this process requires either the housekeeping Isc or the stress-induced Suf pathway.

214 ion observed in A. thaliana mainly producing housekeeping isoprenoid metabolites.

215 n remain problematic, due to the absence of "housekeeping" kinases and the obvious fallacy of the ass

216 ggravates the loss of RNA polymerase II from housekeeping loci, which apparently do not accumulate at

217 ydrogenase (GAPDH) is often used as a stable housekeeping marker for constant gene expression.

218 em, where it probably constitutes a baseline housekeeping mechanism and a first line of defence again

219 st chaperone gene expression is an essential housekeeping mechanism and provides a roadmap for defini

220 method for data normalization by identifying housekeeping microRNA.

221 nous ZnT8 from a basal level to 32.5% of the housekeeping Na(+)/K(+) ATPase on the cell surface, ther

222 tant over the two samples, which function as housekeeping normalization genes.

223 ion when iron is unavailable to activate the housekeeping NrdAB enzyme.

224 domain superfamily, CsrD, in addition to the housekeeping nucleases RNase E and PNPase.

225 llular constituents is critical for cellular housekeeping, nutrient recycling, and various aspects of

226 eep loss, suggesting that it may promote the housekeeping of heavily used and strong synapses in resp

227 of all specialized genes, while sparing the housekeeping ones, and, thus, attenuated pathological hy

228 Transcriptome analyses often have focused on housekeeping or tissue-specific genes or on gene coexpre

229 s mutated in IBMFS frequently participate in housekeeping pathways, which are important for cell grow

230 reated a mouse model that mimicked the human housekeeping pattern of fpgs gene expression.

231 ts, quantitates adduct levels relative to a "housekeeping peptide", and annotates modifications based

232 2alpha activity in the generation of a basal housekeeping PI3P pool and in the control of membrane re

233 Genome packaging is an essential housekeeping process in virtually all organisms for prop

234 ticipates in basic functional and structural housekeeping processes common to all cell types.

235 pivotal role in the mitophagy mitochondrial housekeeping program.

236 diverse developmental pathways and cellular housekeeping programs.

237 TFIIB is constitutively bound to all paused, housekeeping, promoters, whereas de novo recruitment of

238 We use this probe to measure kinase and housekeeping protein activities, separately or simultane

239 nly one protein per assay with an additional housekeeping protein for normalization.

240 ly, it is not understood how deficiency of a housekeeping protein leads to the selective degeneration

241 y, total protein is estimated using either a housekeeping protein or the sample median across all sli

242 stable isotope-labeled standard peptides (or housekeeping protein peptides), but quantitation using w

243 election on the transferrin receptor TfR1, a housekeeping protein required for iron uptake and the ce

244 Alternatively, it may act as a housekeeping protein that regulates the activity of endo

245 t cells requires its binding to an essential housekeeping protein, translation elongation factor Tu (

246 SMN1 encodes SMN, a ubiquitous housekeeping protein, which makes the primarily motor ne

247 encodes beta-actin, an abundant cytoskeletal housekeeping protein.

248 s the major route of initiation of mRNAs for housekeeping proteins and thus, the bulk of protein synt

249 e trends were maintained for subsets of only housekeeping proteins and when moving from exomes of 1,0

250 factors, whereas the process likely involves housekeeping proteins as well.

251 In contrast, levels of many housekeeping proteins did not change.

252 at they have retained typical structural and housekeeping proteins found in nematocysts of jellyfish,

253 own that the expression level of such common housekeeping proteins is, in fact, dependent on various

254 ecursors for the synthesis of peptidoglycan, housekeeping proteins, and virulence factors in bacteria

255 he synthesis of the peptidoglycan cell wall, housekeeping proteins, and virulence factors of bacteria

256 vation among strains in the sequences of the housekeeping proteins, there was significantly greater d

257 ylation sites from 1,257 tissue-specific and housekeeping proteins.

258 ted into two structural/functional classes: "housekeeping" proteins involved in replication and metab

259 mRNAs encoding ribosomal proteins and other 'housekeeping' proteins tending to have shorter tails.

260 atalytic mechanism distinct from that of the housekeeping PTAC.

261 were categorized as constitutively expressed housekeeping, regulated homeostatic, or dynamic early st

262 RhoGDIalpha has been regarded as a housekeeping regulator essential to control homeostasis

263 d have come at some expense to the protein's housekeeping role in aminoacylation and editing.

264 We conclude that MT3 may play a housekeeping role in metal homeostasis, while MT4 may fu

265 Aside from its housekeeping role in the assembly of snRNPs, additional

266 in Gram-negative bacteria has a more global housekeeping role, prompting our investigation to determ

267 suggest that they may carry out an important housekeeping role.

268 ssemblies that have probably served cellular housekeeping roles for at least one billion years, ances

269 ass E sortase (SavSrtE) annotated to perform housekeeping roles in Streptomyces avermitilis Biochemic

270 maged DNA and also allow the study of normal housekeeping roles of PARP-1 with undamaged DNA.

271 he crl gene has two overlapping promoters, a housekeeping, RpoD- (sigma(70)) dependent promoter, and

272 The housekeeping sarco(endo)plasmic reticulum Ca(2+) ATPase

273 is essential for protein export and is the "housekeeping" SecA, whereas SecA2 is an accessory SecA t

274 ion in expression of stress-related, but not housekeeping, selenoproteins.

275 ma factor activity from competition with the housekeeping sigma factor for RNA polymerase and allows

276 dependent upon a consensus sequence for the housekeeping sigma factor SigA and an A+T-rich upstream

277 sigma(G) but not promoters dependent on the housekeeping sigma factor sigma(A) .

278 by RNA polymerase containing sigma(70), the housekeeping sigma factor, but not by RNA polymerase con

279 gages the C terminus of the Escherichia coli housekeeping sigma factor, sigma(70).

280 The housekeeping sigma(70) factor of Escherichia coli recogn

281 (Eco) 6S RNA interacts specifically with the housekeeping sigma(70)-holoenzyme (Esigma(70)) and plays

282 Mtb RbpA-SID in complex with domain 2 of the housekeeping sigma-factor, sigma(A).

283 erved region (NCR), which is present only in housekeeping sigma-factors.

284 Primary, or housekeeping, sigma factors are responsible for most of

285 Housekeeping sigmas direct transcription from thousands

286 r melting, to those universally conserved in housekeeping sigmas relaxed their stringent promoter req

287 We discuss both the housekeeping sigmas, which govern transcription of the m

288 The prototypic housekeeping sortase A (SaSrtA) from Staphylococcus aure

289 In contrast, the housekeeping sortase A (SrtA) is critical for biofilm fo

290 be covalently linked to the cell wall by the housekeeping sortase A.

291 Genetic disruption of the housekeeping sortase in several Gram-positive pathogens

292 and that they govern the pilin-specific and housekeeping sortase specificity.

293 xically, we discovered that depletion of the housekeeping sortase SrtA was lethal for Actinomyces ori

294 ptidoglycan is subsequently catalysed by the housekeeping sortase SrtF.

295 In addition, the housekeeping sortase, SrtA, was found to process EbpB an

296 UMOylations, and one (CrUBC3) is involved in housekeeping SUMOylations.

297 ences in stability between developmental and housekeeping transcripts, although strongly induced RNAs

298 t to no increase in H4K12 acetylation of the housekeeping tubA promoter.

299 iously for different groups of genes such as housekeeping versus regulated genes.

300 oter interactions differentially regulating "housekeeping" versus "developmental" genes.