ライフサイエンスコーパス: how best to

1 rogressive disease, to answer issues such as how best to achieve and maintain optimum glycaemia witho

2 How best to achieve both weight loss and clinical benefi

3 ives, the aim is to facilitate discussion on how best to achieve consensus on this issue by driving t

4 ions about synapses, and discuss ideas about how best to achieve further progress in the field.

5 How best to achieve this goal is unknown.

6 The question now is how best to achieve this?

7 A major challenge in tumor immunology is how best to activate the relatively low avidity self-spe

8 ose of this review is to update providers on how best to address asthma in adolescents.

9 ently, there is no comprehensive guidance on how best to address testing issues specific to MN partic

10 The MS research community needs to determine how best to address two key unanswered questions.

11 A key statistical issue is therefore how best to adjust for the two different probe designs.

12 s methods enable informed decision making on how best to allocate limited resources that could lead t

13 osts also raises further questions regarding how best to allocate mental effort to minimize those cos

14 is is often suggested as a means of deciding how best to allocate resources, but some of its many eth

15 Understanding how best to apply these agents clinically and how they i

16 We are still learning how best to apply this new technology in an environment

17 variation, frustrating efforts to determine how best to apply this treatment tool.

18 n, childhood and adulthood; and to establish how best to apply this understanding to provide individu

19 ard understanding pathophysiology as well as how best to approach surgical management when indicated.

20 ient monitoring, when to change therapy, and how best to approach treatment options, including optima

21 How best to archive and mine the complex data derived fr

22 This review focuses on how best to ascertain the functional relevance of molecu

23 d highly interdisciplinary, understanding of how best to assemble these materials into films or hybri

24 How best to assess therapeutic misconception is unclear.

25 lectivity, allows medicinal chemists to plan how best to block its metabolism.

26 The problem of how best to bring this about is not easy to solve in hig

27 ate erupted in the London medical press over how best to calculate hospital mortality rates.

28 demiological studies have prompted debate on how best to characterise and diagnose this disorder.

29 the cell cycle is critical to understanding how best to clinically develop these agents, both as sin

30 ng randomized clinical trials are evaluating how best to combine currently available therapies, while

31 gnment, little consensus has been reached on how best to construct profile-profile substitution score

32 There is significant controversy about how best to control cholera epidemics in refugee setting

33 This literature is then used to recommend how best to convey preventive messages in today's cost-c

34 and there remains ambiguity about how best to define additional pathways, such as the koni

35 ted with interstitial lung disease (ILD) are how best to define, diagnose, and treat connective tissu

36 presentative papers, however, struggled with how best to define, measure and validate recovery in its

37 burden of melanoma is necessary for deciding how best to deploy limited resources to achieve effectiv

38 with lymphoma, will be critical to determine how best to deploy MRD testing in routine practice and w

39 esearch, but researchers often struggle with how best to derive hits from HTS data.

40 magnetic molecules as a means of determining how best to describe the Nb-arene interactions.

41 treatment and raise further questions about how best to design preclinical studies that can better p

42 ife, clinicians are starting to grapple with how best to detect those at risk of postdeployment adjus

43 multicultural populations and on determining how best to develop such questionnaires.

44 the TDP to enhance the treatment effect and how best to disseminate the TDP without compromising imp

45 How best to do this remains unknown.

46 th researchers and clinicians with regard to how best to document and address its unique health care

47 One topic that has come to the forefront is how best to effectively manage and interpret the large d

48 oach is proposed to promote discussion about how best to enable potential participants to make inform

49 Evidence on how best to enhance discussions about CRC screening opti

50 recasts, an interdisciplinary perspective on how best to ensure ecologically viable continuity of glo

51 of clinical trial endpoints have challenged how best to evaluate promising new therapeutics.

52 preting correlation data and a discussion of how best to evaluate the effect of correlations on corti

53 ing session examined the practical issues of how best to evaluate the nutritionally at-risk host, esp

54 ions to academia, industry and government on how best to expand the role of computation in their scie

55 ble were the critical questions raised as to how best to exploit aberrant signaling pathways associat

56 Furthermore, we discuss how best to exploit genetic background effects to broade

57 eter time series and raising the question of how best to extract insights from such rich data sets.

58 onent of skill acquisition involves learning how best to extract task-relevant information.

59 has become commonplace, leading many to ask how best to follow these patients.

60 In unresectable disease, the question is how best to get the patients to resection.

61 it has also reopened old controversies about how best to guide the development of this field.

62 open consent, and as controversy grows about how best to handle incidental genomic findings, these ap

63 is often critical for organisms to discover how best to harvest resources such as food and water.

64 inal causes but are essential to discovering how best to help the older aging autistic person.

65 re for the critical ill and injured learning how best to hook humans up to machines, we will spend th

66 enges for this emerging field: understanding how best to identify de novo genes, how they arise and w

67 presentative micrographs provide examples of how best to identify human HF stages, even in suboptimal

68 it from the procedure, no guidance exists on how best to identify such patients.

69 nce of learning, and provide no consensus as how best to identify when learning has occurred.

70 We also provide technical advice about how best to image Brainbow-expressing tissue.

71 n basic research, but questions remain about how best to implement and monitor compliance.

72 nciples are formulated to assist in deciding how best to implement each.

73 The challenge is how best to implement imaging in clinical practice to ma

74 e embraced and efforts are made to determine how best to implement in practice.

75 Our understanding on how best to implement this cell-replacement strategy for

76 multaneously, many countries are considering how best to improve the management of their blood invent

77 ppropriately designed studies to investigate how best to improve this situation.

78 and memory; we have little understanding of how best to incorporate physical activity during the day

79 , additional studies are needed to determine how best to incorporate psyllium into existing preventio

80 clinicians and scientists must now determine how best to incorporate rapid changes in our biologic un

81 d on performing clinical trials to determine how best to incorporate rapid detection of MDRO carriage

82 women in whom the tests should be used, and how best to incorporate test results into decision makin

83 hydrophobicity, molecular size) and evaluate how best to incorporate this finding into full-scale des

84 idual tumors will be critical in determining how best to incorporate this promising agent into the ar

85 ers, plans, and physicians as they determine how best to inform patients about managed care.

86 ams, in which training directors must decide how best to integrate neuroscience teaching in a rapidly

87 It remains unclear how best to integrate recent discoveries regarding gliom

88 sensations originating from the same object, how best to integrate them.

89 increasing use of TRT raises the question of how best to integrate TRT into multimodality protocols.

90 mechanism of cell wall assembly and suggest how best to interfere with the process for future antibi

91 od for a specific application or for gauging how best to interpret different sources of data.

92 e care for patients with heart failure (HF), how best to interpret longitudinally collected patient-r

93 lity of 24-hour esophageal pH monitoring and how best to interpret pH test results, 2) definitively d

94 e of DNA microarrays, questions remain about how best to interpret the wealth of gene-by-gene transcr

95 g high-dimensional and heterogeneous data is how best to interrogate increasingly specific subphenoty

96 ile there is as yet no clear consensus about how best to intervene therapeutically in CJD, prion infe

97 We consider how best to leverage genomic data and recent experimenta

98 s critical information about tumor response; how best to leverage this for predicting recurrence-free

99 alike, the current challenge is to determine how best to make SDM a reality in everyday clinical prac

100 e prospective studies are needed to evaluate how best to manage all manifestations of skin inflammati

101 Research is needed to understand how best to manage author FCOIs during guideline creatio

102 ies affect the benefit of device therapy and how best to manage device advisories.

103 There remains controversy about how best to manage intracranial pressure on the ICU; we

104 brain, what is the clinical presentation and how best to manage it.

105 s a need to study why they are so common and how best to manage them.

106 tribute to successful biological control and how best to manipulate augmentative releases into greenh

107 There is debate about how best to measure patient-reported outcomes (PROs) in

108 Current research is focused on evaluating how best to measure the patient assessments and incorpor

109 objective of health care, yet it is unclear how best to measure this in the ICU setting.

110 parents, there is very limited knowledge on how best to meet the mental health needs of young people

111 rvey to better understand what they were and how best to meet them, in the primary care environment.

112 However, how best to minimise the time spent taking cytotoxic dru

113 tients make optimal informed decisions about how best to minimize the risk of this serious complicati

114 ay in autoimmunity will provide insight into how best to modulate this interaction to achieve therape

115 raft and could, therefore, determine help on how best to monitor patients with dnDSA.

116 ts to help might make the problem worse, and how best to move forwards.

117 purpose and value of theoretical models and how best to navigate collaborations between experimental

118 pecifically, research is needed to determine how best to operationalize disclosure processes so as to

119 ions on these parameters, as well as explore how best to optimise recovery and quality of life for su

120 ssion data, relatively little is known as to how best to perform feature selection or classification

121 about which new diagnostics to scale up and how best to position them in diagnostic algorithms.

122 the matrix interact with the algorithm, and how best to predict the probability of observing a previ

123 ugment CTL function, raising the question of how best to present tumor-associated MHC class I epitope

124 Research is needed to better understand how best to prevent and treat hepatitis C in substance u

125 One research challenge is to determine how best to prevent cardiac arrest during severe hemorrh

126 drug development and in the determination of how best to prevent hepatotoxicity after drug approval.

127 little is known about their risk factors and how best to prevent them.

128 or death (SCA/SCD) keep alive a debate as to how best to prevent these tragedies.

129 s on what disease models are appropriate and how best to proceed once high-density genome maps become

130 The question of how best to protect the human population against a poten

131 mbers of procedures to attain competence and how best to provide procedural training.

132 We further propose that studies focused on how best to provide T cell help to B cells that produce

133 d with expertise in building knowledge about how best to provide this care.

134 ces between psychological processes, and for how best to pursue a unified science of the mind.

135 These include how best to rapidly and efficiently identify key genes r

136 However, uncertainty persists as to how best to regress ECG LVH.

137 s commentary examines the evidence regarding how best to replete phosphorous in the hypophosphatemic

138 ing biological terrorism lies in focusing on how best to respond to a terrorist attack.

139 address these issues, and may not understand how best to respond to their patients' spiritual needs.

140 Empirical studies are required on how best to scale up antiviral treatment and combine tre

141 nor-derived infections raise the question of how best to screen donors without excessive restriction

142 However, it is not clear how best to screen for frailty in preoperative surgical

143 It is uncertain how best to screen pregnant women for the presence of fe

144 are important for cancer cells, determining how best to select patients, and developing technologies

145 cer (CRPC) introduce new treatment dilemmas: how best to sequence these options to maximally benefit

146 However, many empiric questions about how best to structure and implement disclosure processes

147 Conflicting findings led to questions of how best to study the role of this variant in human auto

148 Further research is needed to understand how best to support service members and veterans who may

149 It is important to consider how best to sustain population protection in the long te

150 ntervention coverage in these groups, and on how best to sustain, focus, and intensify efforts to pro

151 ceived a simple, 3-step instruction sheet on how best to take photographs using a smartphone (interve

152 econdary analysis to receive instructions on how best to take photographs with smartphones.

153 ed within the plasma membrane will determine how best to target this family of receptors therapeutica

154 inking, and then focus on recent research on how best to teach science to children from preschool to

155 One challenging question is how best to test for significant methylation differences

156 e model's emphasis on temporality challenges how best to think of static art forms.

157 surgeons need to spend focused attention on how best to train and educate upcoming surgical trainees

158 tant question and hence goal in catalysis is how best to transfer the synthetic and mechanistic insig

159 e preferences of their patients to determine how best to translate research to the bedside.

160 How best to translate this increase in immune responsive

161 ities for AF, there is no clear consensus on how best to treat AF with concomitant HFrEF.

162 Other questions include how best to treat an acute attack as well as the optimal

163 How best to treat HIV-infected children who require tube

164 More data are needed to determine how best to treat patients with stage II and stage III M

165 However, there is no consensus on how best to treat these patients.

166 er are elderly, information remains scant on how best to treat these patients.

167 es the promise it still holds, and considers how best to turn promise into reality.

168 t have led me to change my long-term view on how best to understand mind/brain interactions.

169 that it may be in decline, and it considers how best to understand the future spread, containment, a

170 lar basis of mental disorders, to rethinking how best to undertake research on the aetiology, assessm

171 be useful to step for planners to determine how best to use existing platforms for delivering new in

172 ating its mode of action will help to refine how best to use fenofibrate in the management of diabeti

173 t also of practical significance in learning how best to use MLEs in the germline transformation of i

174 titative framework can guide policymakers on how best to use nonpharmaceutical interventions and prio

175 However, little evidence exists on how best to use SIAs to strengthen RI.

176 ve better epidemiologic data, we cannot know how best to use the system's scarce mental health resour

177 d by a medical technology in decisions about how best to use the technology.

178 culture techniques and we are still learning how best to use these approaches.

179 ealth care professionals, who must determine how best to use these technologies to optimize patient c

180 ns, were identified, along with questions of how best to use this body of information to reduce human

181 Future research is needed to determine how best to use this technique for risk stratification.

182 over a 1 year period in order to understand how best to utilise milk for processing throughout the y

183 which glutamine acts will lead to insight on how best to utilize glutamine as a nutritional therapy.

184 its effects will lead to an understanding of how best to utilize glutamine as both a pharmacologic an

185 identified, and further debate is needed on how best to validate chronic disease diagnoses in the GP