ライフサイエンスコーパス: human genome sequence

1 esent, despite their apparent absence in the human genome sequence.

2 human DNA not yet contained in the available human genome sequence.

3 bands in the June 2002 version of the draft human genome sequence.

4 superfamily ribonucleases identified in the human genome sequence.

5 hese tumors with patterns predicted from the human genome sequence.

6 rrations quantitatively from 14 FTC onto the human genome sequence.

7 o be part of a transcriptional module on the human genome sequence.

8 of 524 sites of HIV cDNA integration on the human genome sequence.

9 l genes from regions of interest using draft human genome sequence.

10 complete the assembly and annotation of the human genome sequence.

11 s and in silico restriction digestion of the human genome sequence.

12 was performed using the draft version of the human genome sequence.

13 osition of having two distinct drafts of the human genome sequence.

14 rgeted, single-copy probes directly from the human genome sequence.

15 ompleted >98 Mb ( approximately 3.3%) of the human genome sequence.

16 international effort to determine a complete human genome sequence.

17 s to identify all functional elements of the human genome sequence.

18 cessful in mammals, accounting for 30-40% of human genome sequence.

19 ure has been evolutionarily imprinted on the human genome sequence.

20 s of the largest tandem repeats found in the human genome sequence.

21 ds to rigorously analyze a defined 1% of the human genome sequence.

22 n a population with respect to the reference human genome sequence.

23 agreeing with the location at 1p36.22 in the human genome sequence.

24 were located within 1 to 5 Mb based upon the human genome sequence.

25 tive elements collectively occupy 44% of the human genome sequence.

26 nificant BLASTN hits (E < e(-5)) against the human genome sequence.

27 We have the human genome sequence.

28 their chromosomal locations from the latest human genome sequences.

29 and an expanded set of high-coverage modern human genome sequences.

30 esource to be valuable for the annotation of human genome sequences.

31 to the functional annotation of variation in human genome sequences.

32 e identifiable orthologues in the canine and human genome sequences.

33 le haplotype resolution to become routine in human genome sequencing.

34 nome draft sequence and the Celera assembled human genome sequence, 36% of the STSs had a discrepant

35 human-specific HERV-K(HML2) elements in the human genome sequence, 8 of which are insertionally poly

36 The recent availability of the human genome sequence allowed the identification of thre

37 The completion of the human genome sequence allows for new ways to analyze glo

38 The recent completion of the human genome sequence allows genomics research to focus

39 The availability of both the mouse and human genome sequences allows for the systematic discove

40 levels in this family by using the published human genome sequence and a diverse sample of 19 humans.

41 tions utilize information from the completed human genome sequence and a large, high-quality set of h

42 The availability of a draft human genome sequence and ability to monitor the transcr

43 l know all of the 3 billion DNA bases in the human genome sequence and all of the variations in the g

44 GS patterns with patterns predicted from the human genome sequence and displayed as Virtual Genome Sc

45 With the completion of the human genome sequence and genome sequence available for

46 we mapped expressed sequences onto the draft human genome sequence and only accepted splices that obe

47 The availability of the human genome sequence and progress in sequencing and bio

48 It includes 3,658 genes homologous to the human genome sequence and provides a framework for overl

49 very 5 kilobases that is integrated with the human genome sequence and that is freely available in th

50 r (DOP)-PCR can be precisely mapped onto the human genome sequence and that it is possible to predict

51 lted in accelerated plans for completing the human genome sequence and the earlier-than-anticipated i

52 logies, particularly the availability of the human genome sequence and the ongoing sequencing of canc

53 new tools is the availability of the entire human genome sequence and the prospect that within the n

54 Deciphering the human genome sequence and the publication of the human h

55 The availability of the human genome sequence and tools for interrogating indivi

56 ersity was estimated from an analysis of six human genome sequences and found to deviate from the exp

57 The recent completion of human genome sequencing and advances in DNA microarray t

58 In parallel with the human genome sequencing and assembly effort, many tools

59 Applying this method to data from the Celera human genome sequencing and SNP discovery project, we ob

60 ing oligonucleotide probes designed from the human genome sequence, and hybridizing with "representat

61 identification of transcribed regions in the human genome sequence, and many researchers accept them

62 1) insertions comprise as much as 17% of the human genome sequence, and similar proportions have been

63 nsembl site is one of the leading sources of human genome sequence annotation and provided much of th

64 evolution, yet only a small fraction of the human genome sequence appears to be subject to evolution

65 With the human genome sequence approaching completion, a major ch

66 The internet sites that showcase the human genome sequence are blazing a new trail.

67 NA variation and archival information on the human genome sequence are now readily available.

68 Now that the mouse and human genome sequences are complete, biologists need sys

69 Using current approaches, whole human genome sequences are not typically assembled and d

70 most recent mouse, rat, dog, chimpanzee, and human genome sequence assemblies to compile a near-compl

71 sis of homology between mouse Sycp3 cDNA and human genome sequences at the aminoacid level.

72 er throughput nanopore sequencers, mean that human genome sequencing at scale is now possible.

73 With the completion of the human genome sequence, attention turned to identifying a

74 will be increasingly valuable as additional human genome sequences become available.

75 ge for DNA sequencing remains great, despite human genome sequences being 99.5% identical, the 3 mill

76 fields through the production of a complete human genome sequence, but also had driven the developme

77 ave revolutionized biology by completing the human genome sequence, but in the race to completion we

78 ill be required to obtain the 3-billion-base human genome sequence by the target date of 2005.

79 h the goal of completing the first reference human genome sequence by the year 2005.

80 estigators at the Baylor College of Medicine Human Genome Sequencing Center (BCM-HGSC) and BeeBase or

81 generated at the Baylor College of Medicine Human Genome Sequencing Center were compared with the hu

82 cus genome at the Baylor College of Medicine Human Genome Sequencing Center, the average success rate

83 throughput genomic sequences from the major human genome sequencing centers.

84 ge repository of the data being generated by human genome sequencing centers.

85 rtant implications for efforts to finish the human genome sequence, complicates comparative sequence

86 Alignments of the RH map to macaque and human genome sequences confirm a large inversion and rev

87 e human genome assembly by the International Human Genome Sequencing Consortium (HGSC) and Celera Gen

88 cted gene sets produced by the International Human Genome Sequencing Consortium (HGSC) and Celera Gen

89 me sequencing performed by the International Human Genome Sequencing Consortium (IHGSC) and Celera Ge

90 When the International Human Genome Sequencing Consortium (IHGSC) published its

91 The International Human Genome Sequencing Consortium (IHGSC) recently comp

92 The International Human Genome Sequencing Consortium constructed a map of

93 aft human genome sequence, the International Human Genome Sequencing Consortium has proceeded to fini

94 ed genome was published by the International Human Genome Sequencing Consortium in 2004.

95 lysis of clone overlaps by the International Human Genome Sequencing Consortium.

96 The published human genome sequence contains many thousands of endogen

97 Thus, the human genome sequence contains signatures for chromatin

98 ttle-human comparative map was created using human genome sequence coordinates of the paired ortholog

99 comparative anchor loci is 1.15 Mb based on human genome sequence coordinates.

100 The completion of the human genome sequence, coupled with the imminent complet

101 integrated information from the most current human genome sequence data (UCSC genome assembly Human J

102 sferase, identified by BLAST searches of the human genome sequence data base, has been cloned, expres

103 ith these techniques, a 45x coverage of real human genome sequence data compresses losslessly to unde

104 Due to the large size of human genome sequence data files (varying from 30 GB to

105 ome that accounts for 96.8% of the available human genome sequence data.

106 p encompassing the 300-kb deletion using the human genome sequence database and confirmed the map usi

107 sm (SNP) markers is to take advantage of the human genome sequencing effort currently under way.

108 arched the proteins predicted from the draft human genome sequence for paralogues of known tumour sup

109 A search of the human genome sequences for proteins with a COOH-terminal

110 scalability of this platform enable complete human genome sequencing for the detection of rare varian

111 Alignment of human tauCstF-64 with human genome sequence from chromosome 10 shows that CSTF

112 , we analyzed approximately 300 kilobases of human genome sequence from diverse gene loci and cleanly

113 , on the basis of the assembled nonredundant human genome sequence from the Human Genome Project-Sant

114 t can: (i) retrieve any particular region of human genome sequence from the NCBI database and (ii) an

115 The availability of complete human genome sequences from populations across the world

116 identification from finished and unfinished human genome sequence has become critically important in

117 The human genome sequence has been finished to very high sta

118 The determination of the human genome sequence has brought these metaphors to the

119 The availability of the human genome sequence has enabled the exploration and ex

120 The recent completion of the human genome sequence has enabled the identification of

121 The deciphering of the human genome sequence has enabled the identification of

122 The availability of the complete human genome sequence has highlighted the need for a too

123 Analysis of the human genome sequence has identified approximately 25000

124 Completion of the human genome sequence has inspired a new wave of epidemi

125 The elucidation of the human genome sequence has made it possible to identify g

126 The availability of the human genome sequence has opened up the possibility of i

127 The human genome sequence has profoundly altered our underst

128 The availability of human genome sequence has transformed biomedical researc

129 Human genome sequencing has transformed our understandin

130 Personal diploid human genome sequences have been generated, and each has

131 and challenges that the availability of the human genome sequence holds for cancer research.

132 of Single Nucleotide Polymorphisms (dbSNP), Human Genome Sequencing, Human MapViewer, GeneMap'99, Hu

133 of Single Nucleotide Polymorphisms (dbSNP), Human Genome Sequencing, Human MapViewer, Human inverted

134 A search of the human genome sequence identified the vWF-cleaving protea

135 retation of the information contained in the human genome sequence in terms of the structure, functio

136 A human genome sequenced in only an hour is likely to beco

137 The reported human genome sequence includes about 400 gaps of unknown

138 ens of millions of base pairs of euchromatic human genome sequence, including many protein-coding gen

139 The wealth of human genome sequence information now available, coupled

140 Over one-third of human genome sequence is a product of non-LTR retrotrans

141 The draft human genome sequence is an important step in cataloguin

142 Now that the draft human genome sequence is available, everyone wants to be

143 About 5% of the human genome sequence is composed of the remains of retr

144 Variation in the human genome sequence is key to understanding susceptibi

145 A 'working draft' of the human genome sequence is now available.

146 Human genome sequencing is accelerating rapidly.

147 The progress of human genome sequencing is driving genetic approaches to

148 Although individual human genome sequencing is increasingly routine, nearly

149 Human genome sequencing is routine and will soon be a st

150 With recent access to the entire human genome sequence, it has become possible and highly

151 tant resource for genomic research after the human-genome sequence itself, yet the major gene catalog

152 The availability of the human genome sequence led us to propose that systematic

153 an genetic variation that will come from the human genome sequence makes feasible a polygenic approac

154 us effort committed to the annotation of the human genome sequence, most notably perhaps in the form

155 With the human genome sequence nearing completion, new opportunit

156 The mouse contigs were aligned to the human genome sequence on the basis of 51,486 homology ma

157 demonstrate application of this approach to human genome sequencing on flow-sorted X chromosomes and

158 ith the completion of a draft version of the human genome sequence only a fraction of the genes ident

159 of Single Nucleotide Polymorphisms (dbSNP), Human Genome Sequencing pages, GeneMap'99, Davis Human-M

160 cation in the final stages of completing the Human Genome Sequencing Project and in applications of B

161 the DNA database arising as a result of the human genome sequencing project enabled us to identify A

162 The success of the human genome sequencing project has created wide-spread

163 The completion of the human genome sequencing project has provided a flood of

164 s (PACs) have proved excellent tools for the human genome sequencing projects.

165 witnessed an explosion of successful ancient human genome-sequencing projects, with genomic-scale anc

166 The human genome sequence provides a reference point from wh

167 The finished human genome sequence provides a thorough catalog of the

168 everal advances, including completion of the human genome sequence, publication of genome sequences f

169 lera Genomics produced working drafts of the human genome sequence, published in 2001, but refinement

170 ds that contain a provirus are mapped to the human genome, sequence reads that cannot be localized to

171 Interpretation of the human genome sequence relies on studies of model genetic

172 The human genome sequence remains incomplete, with multimega

173 Clinical adoption of human genome sequencing requires methods that output gen

174 ent of differentially expressed genes to the human genome sequence resulted in a larger number of gen

175 Analysis of these clones and search of the human genome sequence revealed an uncharacterized group

176 he initial analysis of the draft copy of the human genome sequence revealed the presence of several g

177 the recently published essentially finished human genome sequence reveals several thousand undocumen

178 The reference human genome sequence set the stage for studies of genet

179 nomic sequence we obtained and the reference human genome sequence share a most recent common ancesto

180 Analysis of the human genome sequence shows the presence of genes encodi

181 However, findings from the human genome sequence suggest an unprecedented degree of

182 Cebus albifrons) and from the chimpanzee and human genome sequences, suggests that this is the genera

183 Our analyses of human genome sequences syntenic to these regions suggest

184 Can the draft human genome sequence tell us how the cell cycle works a

185 l search for new viruses in some of the many human genome sequences that are now available thanks to

186 ed by MEDCO is a $10 million prize for whole human genome sequencing that will test 100 samples and e

187 After the completion of a draft human genome sequence, the International Human Genome Se

188 With a match to human genome sequences, the approximate location of a qu

189 With the accomplishment of human genome sequencing, the number of sequence-known pr

190 In a large-scale retrospective analysis of human genome sequences, this profile score was shown to

191 comparing their flanking sequences with the human genome sequence; this enabled conserved segments b

192 yield the functional elements buried in the human genome sequence, thus helping to annotate non-codi

193 mpared with the best matching regions of the human genome sequence to assay the amount and kind of DN

194 ficial chromosome (BAC) clones and the draft human genome sequence to complete a contiguous string of

195 and provides a framework for overlaying the human genome sequence to the mouse and for sequencing th

196 The availability of the human genome sequence together with sequenced genomes of

197 apping expressed sequence tags (ESTs) to the human genome sequence using a binary indexing algorithm.

198 and all mRNA sequences were aligned with the human genome sequence using LEADS, Compugen's alternativ

199 uencing technology development; for studying human genome sequence variation; for developing technolo

200 Taking advantage of the human genome sequence, we have performed extensive seque

201 With the availability of the complete human genome sequence, we performed a comprehensive anal

202 Using the compiled human genome sequence, we systematically cataloged all t

203 as potential therapeutic targets, drafts of human genome sequence were interrogated.

204 The potential threat is evident from the human genome sequence, which reveals many past epidemics

205 in 2001, but refinement and analysis of the human genome sequence will continue for the foreseeable

206 Knowledge of the human genome sequence will enable us to understand how t

207 Information from the human genome sequence will eventually alter many aspects

208 The complete human genome sequence will facilitate the identification

209 We discuss how the human genome sequence will further our understanding of

210 The human genome sequence will provide a reference for measu

211 ron structures of genes in finished or draft human genome sequence with a low rate of false-positives

212 Investigation of human genome sequences with a consensus sequence derived

213 source of stable automatic annotation of the human genome sequence, with confirmed gene predictions t