ライフサイエンスコーパス: human hematopoietic stem cell

1 ssociated genes, commonly occurs among aging human hematopoietic stem cells.

2 ted virus vector, followed by engraftment of human hematopoietic stem cells.

3 ortant cytokine for in vitro manipulation of human hematopoietic stem cells.

4 ping active and repressive marks in purified human hematopoietic stem cells.

5 of nonpermissive mice following injection of human hematopoietic stem cells.

6 em cell factor transgene were engrafted with human hematopoietic stem cells.

7 that this system can support self-renewal of human hematopoietic stem cells.

8 of CD34 can be reversible on reconstituting human hematopoietic stem cells.

9 eld of megakaryocytes in cultures of primary human hematopoietic stem cells.

10 molecular regulation of HOXB4 expression in human hematopoietic stem cells.

11 ems to study the biology and transduction of human hematopoietic stem cells.

12 utically useful levels of gene transfer into human hematopoietic stem cells.

13 ere highly efficient in transducing purified human hematopoietic stem cells.

14 at these conditions may support expansion of human hematopoietic stem cells.

15 y the relatively inefficient transduction of human hematopoietic stem cells.

16 that, in addition to being a marker of adult human hematopoietic stem cells, ACE identifies embryonic

17 34 molecule, expressed almost exclusively on human hematopoietic stem cells and committed progenitors

18 Humanized mice engrafted with human hematopoietic stem cells and developing functional

19 ing with an evaluation of candidate genes in human hematopoietic stem cells and in zebrafish revealed

20 d as a common marker expressed on murine and human hematopoietic stem cells and on cells of the hemat

21 lobal gene expression profiles for mouse and human hematopoietic stem cells and other stages of the h

22 f cytokines for use in in vitro expansion of human hematopoietic stem cells and progenitors.

23 6 fresh myeloid leukemia samples, and normal human hematopoietic stem cells and their mature progeny.

24 a prioritized candidate gene with the use of human hematopoietic stem cells and zebrafish embryos.

25 human immune system following engraftment of human hematopoietic stem cells, and 4) the ability of th

26 with observations in mice, and indicate that human hematopoietic stem cells are enriched in the Kit(l

27 Human hematopoietic stem cells are pluripotent, ie, capa

28 upport the concept that telomerase levels in human hematopoietic stem cells are tightly controlled as

29 assay, the best in vitro surrogate test for human hematopoietic stem cells, as well as of the output

30 The efficiency of gene transfer into human hematopoietic stem cells by oncoretroviral vectors

31 leukemia (CML) is a malignant disease of the human hematopoietic stem cell caused by the BCR/ABL gene

32 caveats and utility of this model to analyze human hematopoietic stem cell control in vivo.

33 and flow cytometric analyses confirmed that human hematopoietic stem cells cultured in the presence

34 Purified human hematopoietic stem cells develop into mature T lym

35 ults contribute to a better understanding of human hematopoietic stem cell differentiation and provid

36 g2(-/-) gamma(C)(-/-) mice transplanted with human hematopoietic stem cells (DKO-hu-HSC mice) mimic a

37 el of human-pig chimerism, we show that some human hematopoietic stem cells engrafted in pigs contain

38 We examined Borrelia hermsii infection in human hematopoietic stem cell-engrafted nonobese diabeti

39 e variants of a novel cytokine receptor from human hematopoietic stem cells expressing the CD34 antig

40 4(+) or highly purified CD34(+)CD38(-)CD7(-) human hematopoietic stem cells from umbilical cord blood

41 bined immunodeficient (NOD/SCID) mice accept human hematopoietic stem cell grafts, providing a unique

42 In CD34(+) human hematopoietic stem cells (hHSC) and K526 cells, th

43 an T cells in vivo from genetically modified human hematopoietic stem cells (hHSC) using a human/mous

44 mouse models, the hu-HSC model is created by human hematopoietic stem cell (HSC) engraftment whereas

45 Age-related human hematopoietic stem cell (HSC) exhaustion and myelo

46 actors (GFs) that together promote quiescent human hematopoietic stem cell (HSC) expansion ex vivo ha

47 actors (GFs) that together promote quiescent human hematopoietic stem cell (HSC) expansion ex vivo ha

48 ietic stem and progenitor cells (HSPCs), the human hematopoietic stem cell (HSC) hierarchy contains a

49 methyluracil) to monitor models of mouse and human hematopoietic stem cell (HSC) transplantation.

50 Cotransplantation of human CD34(+) human hematopoietic stem cells (HSC) and hepatocyte prog

51 ficient retroviral-mediated gene transfer to human hematopoietic stem cells (HSC) and insufficient ge

52 expression profile of highly enriched normal human hematopoietic stem cells (HSC) and leukemic stem c

53 ropic retrovirus-mediated gene transfer into human hematopoietic stem cells (HSC) has been a major im

54 Ex vivo amplification of human hematopoietic stem cells (HSC) without loss of the

55 er for the isolation and characterization of human hematopoietic stem cells (HSCs) and cancer stem ce

56 34 antigen is expressed on most, if not all, human hematopoietic stem cells (HSCs) and hematopoietic

57 Finally, based on nucleosome data from the human hematopoietic stem cells (HSCs) and mouse embryoni

58 Efforts to change the fate of human hematopoietic stem cells (HSCs) and progenitor cel

59 Human hematopoietic stem cells (HSCs) are commonly purif

60 Human hematopoietic stem cells (HSCs) are generally rega

61 Human hematopoietic stem cells (HSCs) exposed to cytokin

62 Generating human hematopoietic stem cells (HSCs) from autologous ti

63 date, reconstitution of murine strains with human hematopoietic stem cells (HSCs) from patients with

64 De novo generation of human hematopoietic stem cells (HSCs) from renewable cel

65 However, the effects of hypoxia on human hematopoietic stem cells (HSCs) have not been char

66 Efficient gene transfer into human hematopoietic stem cells (HSCs) is an important go

67 Gene transduction of pluripotent human hematopoietic stem cells (HSCs) is necessary for s

68 Expression of AML1-ETO in human hematopoietic stem cells (HSCs) preferentially enh

69 ncies using mice reconstituted with modified human hematopoietic stem cells (HSCs) remains unclear.

70 further humanized through the engraftment of human hematopoietic stem cells (HSCs) that can lead to h

71 ting potential (MRP) of different sources of human hematopoietic stem cells (HSCs) was directly compa

72 The low levels of transduction of human hematopoietic stem cells (HSCs) with Moloney murin

73 ered by the low frequency of transduction of human hematopoietic stem cells (HSCs) with retroviral ve

74 factor (G-CSF) to promote granulopoiesis of human hematopoietic stem cells (HSCs), neutropenia remai

75 ophage-mediated phagocytosis of transplanted human hematopoietic stem cells (HSCs).

76 antability using limited numbers of purified human hematopoietic stem cells (HSCs).

77 mice as an in vivo assay for transplantable human hematopoietic stem cells (HSCs).

78 , and macrophages after transplantation with human hematopoietic stem cells (hu-HSC) and develops in

79 OD)-scid IL2rgamma(null) mice engrafted with human hematopoietic stem cells (hu-SRC-SCID mice) to cau

80 D/SCID/IL2Rgamma(-/-) mice transplanted with human hematopoietic stem cells [humanized bone marrow li

81 Engraftment of human hematopoietic stem cells in newborn NRG-Akita and

82 Engraftment of human hematopoietic stem cells into immunodeficient mice

83 Transplantation of CD34(+) human hematopoietic stem cells into NSG-SGM3 mice led to

84 Transplantation of human hematopoietic stem cells into severely immunocompr

85 ntly identified cell-surface marker of adult human hematopoietic stem cells, is already expressed in

86 fort to discover specific markers to isolate human hematopoietic stem cells, Jokubaitis and colleague

87 large transgene cassette can be achieved in human hematopoietic stem cell lines.

88 and Milyavsky et al. now show that mouse and human hematopoietic stem cells make opposing decisions a

89 bone marrow transplantation into rodents and humans, hematopoietic stem cells migrate into the liver

90 ese observations indicate that fractionating human hematopoietic stem cells on the basis of ALDH acti

91 ewal, differentiation, and transformation of human hematopoietic stem cells or to evaluate the effica

92 neage developmental potential of a candidate human hematopoietic stem cell population, CD34+CD38- cel

93 )/(-) mice humanized with cord blood-derived human hematopoietic stem cells produce human T cells tha

94 model of DF in which mice transplanted with human hematopoietic stem cells produced signs of DENV di

95 he transplantation of defined populations of human hematopoietic stem cells resulted in the establish

96 Murine and human hematopoietic stem cells share a number of express

97 ssed in proliferating adult cells, including human hematopoietic stem cells, T-lymphocytes, and eryth

98 been able to engraft murine recipients with human hematopoietic stem cells that develop into functio

99 , the feasibility of 2bF8LV gene delivery to human hematopoietic stem cells to introduce FVIII expres

100 Retroviral-mediated transduction of human hematopoietic stem cells to provide a lifelong sup

101 rapy of blood disorders is the resistance of human hematopoietic stem cells to stable genetic modific

102 use it has proven predictive for outcomes in human hematopoietic stem cell transplantation.

103 feration and engraftment potential of normal human hematopoietic stem cells via the engagement of pur

104 Flu toxicity to human hematopoietic stem cells was evaluated by CD34+ ce

105 Using human hematopoietic stem cells, we show that inhibition