ライフサイエンスコーパス: hyaluronic acid

1 and sinusoidal endothelial cell dysfunction (hyaluronic acid).

2 44, a cell-surface glycoprotein receptor for hyaluronic acid.

3 growth factor, hepatocyte growth factor, and hyaluronic acid.

4 3 months, and 22 used cross-linked forms of hyaluronic acid.

5 ream of hyl are also essential for growth on hyaluronic acid.

6 rted by direct binding of IgM to heparin and hyaluronic acid.

7 ced a systemic marker of inflammation, serum hyaluronic acid.

8 wn Norway rats by subretinal injection of 1% hyaluronic acid.

9 size was 0.39 (95% CI 0.18, 0.59), favoring hyaluronic acid.

10 more effective for pain than intraarticular hyaluronic acid.

11 The mice also received intraperitoneal hyaluronic acid.

12 12 it was 0.35 (95% CI 0.03, 0.66) favoring hyaluronic acid.

13 cilitates pancreatic cancer cell adhesion to hyaluronic acid.

14 wn Norway rats by subretinal injection of 1% hyaluronic acid.

15 hyaluronidase family of enzymes that degrade hyaluronic acid.

16 express HYAL1 hyaluronidase, which degrades hyaluronic acid.

17 15, IFN-alpha, hepatocyte growth factor, and hyaluronic acid.

18 82-89% with initial injection of dextranomer/hyaluronic acid.

19 ng is inhibited by the addition of unlabeled hyaluronic acid.

20 13(-/-) mice, as measured by serum levels of hyaluronic acid.

21 covalently crosslinked hydrogels formed from hyaluronic acid.

22 vitro and in vivo, including JAK2/STAT3 and hyaluronic acid.

23 ses in the abundance of soluble collagen and hyaluronic acid.

24 ices versus the active controls treated with hyaluronic acid.

25 , including mTOR, osteoglycin and binding of hyaluronic acid.

26 18, high-sensitivity C-reactive protein, or hyaluronic acid.

27 ic ethanol feeding with small-specific sized hyaluronic acid 35 (HA35) normalizes TLR4 signaling; how

28 The control group received intra-articular hyaluronic acid (60 mg, single dose).

29 hed over the past year evaluating the use of hyaluronic acid (a visco-supplement) or corticosteroid i

30 nds include bacterial lipopolysaccharide and hyaluronic acid, a component of the extracellular matrix

31 In contrast, addition of hyaluronic acid, a nonsulfated glycosaminoglycan, had no

32 Equipped with an outer shell crosslinked by hyaluronic acid, a specific tumour-targeting ligand, the

33 Equipped with hyaluronic acid, a tumour-targeting ligand, this formula

34 and significant reduction in accumulation of hyaluronic acid-a high molecular extracellular matrix gl

35 ation/reorientation, accompanied by restored hyaluronic acid accumulation in the palatal mesenchyme.

36 potent stimulator of inflammation, fibrosis, hyaluronic acid accumulation, myofibroblast accumulation

37 fabricated from natural polymers (chitosan, hyaluronic acid, alginates, gelatin, heparin, chondroiti

38 ic polymers polyethylene glycol, dextran, or hyaluronic acid also reduces inactivation in all three.

39 used to identify an algorithm combining age, hyaluronic acid, amino-terminal propeptide of type III c

40 se-2 by DC maturation allowed degradation of hyaluronic acid and abrogated LC-DC interactions.

41 d-type NEP demonstrate decreased adhesion to hyaluronic acid and cell migration.

42 IPF, soluble factors such as short-fragment hyaluronic acid and cells such as CD11b(+) macrophages c

43 h selectivity (>90-fold) toward heparin over hyaluronic acid and chondroitin sulfate.

44 ctive over other glycosaminoglycans, such as hyaluronic acid and chondroitin sulfate.

45 ingly, when embedded in a 3D ECM composed of hyaluronic acid and collagen, BTICs exhibited opposite d

46 l brain, CSPGs are thought to associate with hyaluronic acid and glycoproteins such as the tenascins

47 identify the polyanionic glycosaminoglycans hyaluronic acid and heparan sulfate as two key macromole

48 Detectable hyaluronic acid and higher d-dimer, interleukin 6, inter

49 d that the interaction between C. neoformans hyaluronic acid and human brain endothelial CD44 could b

50 Hyaluronic acid and HYAL1-type hyaluronidase show high a

51 nhibition is specific for cells migrating on hyaluronic acid and is reversed by synthetic peptide rep

52 r seems to function as the main receptor for hyaluronic acid and osteopontin, serving as coreceptor f

53 of the Scissor system using the ECM element hyaluronic acid and test formulations of insulin and fou

54 wn-Norway rats by subretinal injection of 1% hyaluronic acid and the intraretinal levels of the autop

55 ible hydrogel, based on thiol-functionalized hyaluronic acid and thiol-functionalized gelatin, which

56 ying two different biopolymers (alginate and hyaluronic acid) and mouse bone marrow stromal cells.

57 n microscopy shows that polyethylene glycol, hyaluronic acid, and albumin do not adsorb to the surfac

58 size was 0.22 (95% CI -0.05, 0.49) favoring hyaluronic acid, and at week 12 it was 0.35 (95% CI 0.03

59 timal ratios were controllably conjugated to hyaluronic acid, and elicited significant tumor reductio

60 spatial and temporal changes in tenascin-C, hyaluronic acid, and fibronectin ECM distribution as ear

61 ed glycoprotein (MAGP)-1, decorin, versican, hyaluronic acid, and five types of collagen (I, III, IV,

62 ratin, laminin, collagen type I, fibrinogen, hyaluronic acid, and heparin.

63 coccal pyrogenic exotoxin B (SpeB), capsular hyaluronic acid, and proteins that allow host plasmin as

64 DSP binds biotin-labeled hyaluronic acid, and such binding is inhibited by the ad

65 uction, whereas pulling on syndecan-1, CD44, hyaluronic acid, and with control probes did not.

66 lycan (GAG), generated from the sulfation of hyaluronic acid, are anti-inflammatory but have difficul

67 t the hypothesis that S. pneumoniae utilizes hyaluronic acid as a carbon source during colonization.

68 rcine submaxillary mucins (BSM and PSM), and hyaluronic acid as well as proteoglycan N-linked glycosi

69 lginate, but poly-beta-D-glucuronic acid and hyaluronic acid as well.

70 minotransferase [AST]/platelet ratio, FIB-4, hyaluronic acid, AST/alanine aminotransferase ratio, and

71 We adapted the biophysical properties of hyaluronic acid-based hydrogels to support the different

72 Alternatively, when DOX was encapsulated in hyaluronic acid-based nanoparticles (HAC/DOX) and intrav

73 Herein, we developed hyaluronic acid-based substrates capable of sequential p

74 aluronan (HA) localization with biotinylated hyaluronic acid binding protein (b-HABP), and analyses o

75 rowth factor binding protein-3, IGFBP-3) and hyaluronic acid) binding activity.

76 The hyaluronic acid-binding peptide (HABP) PEP35 was assesse

77 n is a large chondroitin sulfate-containing, hyaluronic acid-binding proteoglycan present in the extr

78 enotype is due to abundant production of the hyaluronic acid capsular polysaccharide, a key virulence

79 on of virulence factors, one of which is the hyaluronic acid capsule (encoded by genes in the has ope

80 eins (sfbI and fbp54), streptolysin O (slo), hyaluronic acid capsule (hasA), streptokinase (ska), and

81 including those for strong repression of the hyaluronic acid capsule and cysteine protease production

82 egulates the abundance of mRNAs encoding the hyaluronic acid capsule biosynthesis proteins (hasABC; a

83 tation in the hasA gene resulting in loss of hyaluronic acid capsule biosynthesis.

84 ve antigen, as well as hasACB, providing for hyaluronic acid capsule formation, two traits that each

85 t cations on expression of the Csr-regulated hyaluronic acid capsule genes (hasABC) by measuring chlo

86 demonstrate that pneumococci can utilize the hyaluronic acid capsule of other bacterial species for g

87 ghly virulent in mice due to derepression of hyaluronic acid capsule synthesis and exotoxins, e.g., s

88 ticular, the pattern of polymorphisms in the hyaluronic acid capsule synthesis operon was especially

89 s encoding a two-component regulator and the hyaluronic acid capsule virulence factor.

90 r initial cell-surface interactions, and the hyaluronic acid capsule, required for subsequent maturat

91 several important virulence factors like the hyaluronic acid capsule.

92 ed lower levels of the anthrax toxins and no hyaluronic acid capsule.

93 nding (GRAB) protein, and the antiphagocytic hyaluronic acid capsule.

94 Pretreatment of chondrocytes with hyaluronic acid caused a decrease of mitochondrial DNA d

95 adenoviral vector transgene expression in a hyaluronic acid-CD44 independent manner that is down-reg

96 stigated the constituent of the PC formed by hyaluronic acid-coated chitosan NPs (HA-CS NPs).

97 d was attenuated in growth on cellobiose and hyaluronic acid compared to the growth of wild-type D39.

98 pathology and increased levels of pulmonary hyaluronic acid, compared to mice infected with the wild

99 with indirect lung injury, while circulating hyaluronic acid concentrations were elevated (32-fold) i

100 G (heparan sulfate, chondroitin sulfate, and hyaluronic acid) concentrations as well as patterns of h

101 mized to receive the matrix therapy agent or hyaluronic acid-containing eyedrops, 0.1%, every other d

102 Dextranomer/hyaluronic acid copolymer has emerged as the favored bul

103 The expression of hyaluronic acid, COX-2, and macrophage inflammatory prot

104 The chemical synthesis of a hyaluronic acid decasaccharide using the preactivation-b

105 d the pooled effect size for intra-articular hyaluronic acid decreased to 0.19 (95% CI, 0.10-0.27).

106 st be aware of the potential for dextranomer/hyaluronic acid (Deflux) implants to mimic distal ureter

107 ctivity is substrate-dependent, with optimal hyaluronic acid degradation at pH 5, poly-beta-D-glucuro

108 idative/nitrosative damage and prevention of hyaluronic acid degradation.

109 Aggrecan retained its function of binding hyaluronic acid despite substantial nitration.

110 hondroitin sulphate, and entactin/fibrinogen/hyaluronic acid) did not.

111 nel-dependent LTP is known to be impaired by hyaluronic acid digestion.

112 Endogenous hyaluronic acid expression is markedly increased in DSS-

113 n, and 47 of 53 (89%) provided training with hyaluronic acid fillers.

114 ion, activated stellate cells use CD44v6 and hyaluronic acid for migration.

115 nanoparticles are composed of biodegradable hyaluronic acid, for tumor targeting and cellular delive

116 , an inflammatory stimulus, such as low m.w. hyaluronic acid from the extracellular matrix, must also

117 We use this model to study the binding of hyaluronic acid functionalized with host molecules to tu

118 Neuromodulators and hyaluronic acid gel fillers have been shown to be well t

119 s been described, with botulinum A toxin and hyaluronic acid; graded full-thickness blepharotomy rema

120 matrix therapy agent group compared with the hyaluronic acid group (4.4 vs 6.1 days; mean difference,

121 n the matrix therapy agent group than in the hyaluronic acid group as measured with OCT (12.4 vs 23.9

122 d how E-selectin-dependent rolling modulates hyaluronic acid (HA) adhesion as a function of fluid she

123 plasmids encoding anthrax toxins as well as hyaluronic acid (HA) and B. cereus exopolysaccharide (BP

124 Charge interaction between polyanionic hyaluronic acid (HA) and cationic AuNPs stabilized with

125 We investigated the contributions of hyaluronic acid (HA) and chondroitin sulfate (CS) to glo

126 atrix (ECM), which is relatively enriched in hyaluronic acid (HA) and flexible.

127 Major constituents of the VB are hyaluronic acid (HA) and glycosaminoglycans (GAGs), both

128 sociated with a time-dependent deposition of hyaluronic acid (HA) and increased expression of markers

129 class I hyaluronan synthases (HASs) elongate hyaluronic acid (HA) by addition to the reducing or the

130 whey formulated media for the production of hyaluronic acid (HA) by Streptococcus zooepidemicus.

131 maturation were those that produced abundant hyaluronic acid (HA) capsular polysaccharide and/or larg

132 The hyaluronic acid (HA) capsule of GAS is a major virulence

133 nes (group A Streptococcus [GAS]) produces a hyaluronic acid (HA) capsule that plays critical roles i

134 Group A streptococcus (GAS) depends on a hyaluronic acid (HA) capsule to evade phagocytosis and t

135 Plasma hyaluronic acid (HA) concentrations decreased in paralle

136 c membrane consists of high molecular weight hyaluronic acid (HA) covalently linked to the heavy chai

137 Hyaluronic acid (HA) drug conjugates with distinct linke

138 hat interactions between lymphocyte CD44 and hyaluronic acid (HA) expressed on dermal vessels in aGVH

139 A single treatment of hyaluronic acid (HA) filler, 20 mg/mL, may provide an im

140 f neutrophil-attracting factors and protects hyaluronic acid (HA) from damage.

141 Recently, hyaluronic acid (HA) has been suggested as an additional

142 t the development of a new cationic liposome-hyaluronic acid (HA) hybrid nanoparticle (NP) system and

143 We investigated synthetic, tunable hyaluronic acid (HA) hydrogels and determined both the a

144 Methacrylated hyaluronic acid (HA) hydrogels provide a backbone polyme

145 We developed a class of hyaluronic acid (HA) hydrogels that form through noncova

146 Shear-thinning, injectable hyaluronic acid (HA) hydrogels were formed through supra

147 Hyaluronic acid (HA) hydrogels were selected because of

148 e demonstrate that in covalently crosslinked hyaluronic acid (HA) hydrogels, the differentiation of h

149 This article describes the use of hyaluronic acid (HA) in combination with Rho-kinase inhi

150 erived hyaluronidase (HAase) HYAL-1 degrades hyaluronic acid (HA) into proangiogenic fragments that s

151 Hyaluronic acid (HA) is a glycosaminoglycan that promote

152 Hyaluronic acid (HA) is a large glycosaminoglycan abunda

153 Hyaluronic acid (HA) is a major component of the glycoca

154 Hyaluronic acid (HA) is a major extracellular matrix pro

155 Hyaluronic acid (HA) is abundant in cartilage and synovi

156 Because hyaluronic acid (HA) is found in many surgical viscoelas

157 High molecular weight hyaluronic acid (HA) is used as a lubricant in OA therap

158 and interleukin 6 (IL-6) levels and pre-ART hyaluronic acid (HA) levels were associated with new AID

159 allenge using cisplatin loaded CD44 targeted hyaluronic acid (HA) nanoparticle (NP) induced synergist

160 ironments containing pathological amounts of hyaluronic acid (HA) or chondroitin sulfate (CS) did not

161 Hyaluronic acid (HA) promotes tumor metastasis and is an

162 The hyaluronic acid (HA) receptor for endocytosis (HARE) is

163 The hyaluronic acid (HA) receptor for endocytosis (HARE; als

164 satile method to transiently overexpress the hyaluronic acid (HA) receptor, CD44, on MSC membranes, t

165 4-Methylumbelliferone (4-MU) is a hyaluronic acid (HA) synthesis inhibitor with anticancer

166 function and permeability were determined by hyaluronic acid (HA) uptake and multiple indicator dilut

167 Hyaluronic acid (HA), a glycosaminoglycan located betwee

168 face coating platform to non-covalently bind hyaluronic acid (HA), a natural lubricant in the body.

169 Hyaluronic acid (HA), an immunoneutral polysaccharide th

170 atrix remodeling was defined by detection of hyaluronic acid (HA), an inhibitor of preOL maturation,

171 the presence or absence of unlabeled sCD44, hyaluronic acid (HA), and a selected 10-mer HA binding p

172 l components of cartilage: type II collagen, hyaluronic acid (HA), and glycosaminoglycans (GAGs).

173 al peptide of type III procollagen (PIIINP), hyaluronic acid (HA), and YKL-40 levels were determined

174 We identify hyaluronan, or hyaluronic acid (HA), as the primary matrix determinant

175 DS), chondroitin sulfate (CS), heparin (HP), hyaluronic acid (HA), chitosan (CH)] and model protein l

176 ntrinsic micro-regional interactions between hyaluronic acid (HA), collagen and the spatial origins o

177 todomain of CD44, the principal receptor for hyaluronic acid (HA), is shed as a 32-kDa fragment-solub

178 regulate the metabolism and the signaling of hyaluronic acid (HA), the major component of the extrace

179 to ensure that the viscous properties of the hyaluronic acid (HA)-based hydrogel are close to the bio

180 ry, a matrix metalloprotease (MMP)-sensitive hyaluronic acid (HA)-based hydrogel was used for BMP-2 d

181 We hypothesized that hyaluronic acid (HA)-based in-situ crosslinkable hydroge

182 further functionalized this Zn-DPA analog to hyaluronic acid (HA)-based self-assembled nanoparticles

183 ndroitin (CH), chondroitin sulfate (CS), and hyaluronic acid (HA)-glycosaminoglycans (GAGs) that play

184 e and efficient strategy for this delivering hyaluronic acid (HA)-modified RNase A (RNase A-HA) in na

185 PP) anions and were successively coated with hyaluronic acid (HA).

186 sPLA(2) activity as chemical conjugates with hyaluronic acid (HA).

187 lfate (KS), chondroitin sulfate A (CSA), and hyaluronic acid (HA).

188 ration of anti-CD44 neutralizing antibody or hyaluronic acid (HA).

189 enhance topical delivery of a macromolecule, hyaluronic acid (HA, MW: 200-325kDa).

190 ispersed in aldehyde- and hydrazide-modified hyaluronic acids (HA), then combined via a double-barrel

191 Here monodisperse synthetic hyaluronan (or hyaluronic acid [HA]) complexes in the approximately 1-

192 cascade activation [D-dimer], and fibrosis (hyaluronic acid [HA]) were measured at baseline and thro

193 Hyaluronan (hyaluronic acid, HA) is a glycosaminoglycan in the extra

194 Hyaluronan (hyaluronic acid; HA) instillation to the bladder has bee

195 The same dilution of hyaluronic acid had no effect on rosetting.

196 both evaluating the highest-molecular-weight hyaluronic acid, had effect sizes in excess of 1.5.

197 ches have equal efficacy, but beyond week 8, hyaluronic acid has greater efficacy.

198 RD was induced by transscleral injection of hyaluronic acid (Healon) or sterile balanced salt soluti

199 Moreover, CCl(4)-induced serum hyaluronic acid, hepatic tissue levels of alpha-SMA or a

200 same building blocks previously employed for hyaluronic acid hexasaccharide syntheses failed to yield

201 platelet count, albumin, bilirubin, INR, and hyaluronic acid; however, changes in these did not corre

202 Vs are self-assembled from hypoxia-sensitive hyaluronic acid (HS-HA) conjugated with 2-nitroimidazole

203 y was used to test human DBM formulated with hyaluronic acid (HY) and cancellous and cortical bone gr

204 we developed a series of heparin-containing hyaluronic acid (HyA)-based hydrogels with various degre

205 s paper shows that the injection of a porous hyaluronic acid hydrogel into the stroke cavity signific

206 Here, we show that a hyaluronic acid hydrogel system enables, across a physio

207 We developed a hyaluronic acid hydrogel that uses a tandem crosslinking

208 ESA was encapsulated in hyaluronic acid hydrogels during gel formation, and then

209 throughput platform based on light-modulated hyaluronic acid hydrogels that enables imposition of mut

210 nt therapeutic mechanisms for the actions of hyaluronic acid in osteoarthritis.

211 may mediate ETV1's significant expansion of hyaluronic acid in PDAC stroma.

212 DSS induced a marked increase in hyaluronic acid in the lamina propria of wild-type but n

213 Cre;Etv1(fl/fl)) reduced levels of SPARC and hyaluronic acid in the stroma.

214 vel function for pneumococcal degradation of hyaluronic acid in vivo and provide mechanistic details

215 higher amounts of HYAL1 (in tumor cells) and hyaluronic acid (in tumor-associated stroma) than HYAL1-

216 Exogenous hyaluronic acid induced the expression of tumor necrosis

217 iated motility) was originally implicated in hyaluronic-acid-induced motility but has since been show

218 press a hyaluronate lyase (Hyl) that cleaves hyaluronic acid into disaccharides, we hypothesized that

219 reated in Brown Norway rats by injecting 10% hyaluronic acid into the subretinal space using a transv

220 ated in Brown Norway rats by injection of 1% hyaluronic acid into the subretinal space.

221 reated in Brown-Norway rats by injecting 10% hyaluronic acid into the subretinal space.

222 Injection of dermal filler, cross-linked hyaluronic acid, into the skin of individuals over 70 ye

223 Intra-articular hyaluronic acid is a US Food and Drug Administration-app

224 The glycosaminoglycan hyaluronic acid is present on the apical surface of airw

225 Hyaluronic acid is widely used in the treatment of osteo

226 D44, known primarily for its role in binding hyaluronic acid, is characteristically expressed on HSPC

227 ementation, the intra-articular injection of hyaluronic acid, is widely used for symptomatic knee ost

228 ded bile production, serum transaminases and hyaluronic acid levels (cellular damage), and base defic

229 c sinusoidal endothelium and increased serum hyaluronic acid levels, along with superior transplanted

230 ts were examined by tissue morphology, serum hyaluronic acid levels, and liver tests (endothelial and

231 ng heparan sulfate, chondroitin sulfate, and hyaluronic acid) lining the vascular lumen.

232 In addition to hyaluronic acid, lipids are particularly relevant for lu

233 a core-membrane structured lipid-polycation-hyaluronic acid (LPH) nanoparticle for systemic gene del

234 performance of LSM was comparable to that of hyaluronic acid measurement but superior to the aspartat

235 Protein kinase Calpha and the receptor for hyaluronic acid-mediated motility (RHAMM) regulate divis

236 Human RHAMM (receptor for hyaluronic-acid-mediated motility) was originally implic

237 k focuses on the investigation of injectable hyaluronic acid (MeHA) hydrogels that have tunable mecha

238 f doxorubicin in small molecular form versus hyaluronic acid nanoparticle (NP) formulation in MCF-7 a

239 sulated microRNA-34a in our well-established Hyaluronic-Acid nanoparticles and delivered to cisplatin

240 stigated the impact of small, specific-sized hyaluronic acid of 35 kD (HA35) on ethanol-induced sensi

241 Langerin recognized hyaluronic acid on DCs and removal of these carbohydrate

242 esized that the chondroprotective effects of hyaluronic acid on oxidatively stressed chondrocytes are

243 Engagement of CD44 by its natural ligands, hyaluronic acid or chondroitin sulfate, protected CLL ce

244 n-invasive markers of liver fibrosis such as hyaluronic acid or procollagen-III-peptide.

245 red with mesenchymal stromal cells (MSCs) or hyaluronic acid or when they were stimulated via ligatio

246 of albumin (P = .051), and higher levels of hyaluronic acid (P < .001) with an area under the receiv

247 Because heavy chain-hyaluronic acid/pentraxin 3 (HC-HA/PTX3) purified from h

248 A using hyaluronic acid-poly(ethylene imine)/hyaluronic acid-poly(ethylene glycol) (HA-PEI/HA-PEG) se

249 b-2 (miR-125b2) expressing plasmid DNA using hyaluronic acid-poly(ethylene imine)/hyaluronic acid-pol

250 zyme hyaluronidase (HysA), which cleaves the hyaluronic acid polymer at the beta-1,4 glycosidic bond.

251 ections of agents such as corticosteroid and hyaluronic acid preparations has been assessed.

252 nization, and matrix metalloproteinase 2 and hyaluronic acid production.

253 in Th differentiation, osteopontin, but not hyaluronic acid, promoted Th1/Th17 differentiation.

254 Hyaluronic acid promotes tumor progression; however, the

255 Lymphatic vessel endothelial hyaluronic acid receptor (LYVE-1) is a newly discovered

256 Lymphatic vessel endothelial hyaluronic acid receptor (LYVE-1) is a recently defined

257 essed F4/80 and lymphatic vessel endothelial hyaluronic acid receptor and produced VEGFC.

258 nvestigated the presence on LAM cells of the hyaluronic acid receptor CD44 and its splice variants as

259 were enriched for cells expressing the major hyaluronic acid receptor CD44.

260 The hyaluronic acid receptor for endocytosis (HARE; also des

261 The hyaluronic acid receptor, CD44, exists as multiple splic

262 We also found that a secondary hyaluronic acid receptor, RHAMM (receptor of hyaluronan-

263 Similarly, sulfated hyaluronic acid (sHA) has not been evaluated for biologi

264 of genes involving PKA, Wnt, Lhx1, FGF8, and hyaluronic acid signaling regulating the transition of n

265 ranching and reduced extracellular matrix by hyaluronic acid staining, all of which are associated wi

266 atively, through the formation of cable-like hyaluronic acid structures.

267 Hyaluronic acid supported significant pneumococcal growt

268 , we identified a posteriorly-enriched gene, Hyaluronic Acid Synthase 2 (Has2), which encodes a key e

269 cid and UDP-N-Acetyl-Glucosamine, as well as hyaluronic acid synthase which forms the disaccharide ch

270 so induced the MyD88-dependent expression of hyaluronic acid synthases 2 and 3, enzymes involved in h

271 ctivates angiogenesis, triggers collagen and hyaluronic acid synthesis and the formation of the extra

272 acid synthases 2 and 3, enzymes involved in hyaluronic acid synthesis, in lamina propria macrophages

273 that key components of this dynamic matrix, hyaluronic acid, tenascin-C and fibronectin, differentia

274 expression of a transitional matrix rich in hyaluronic acid, tenascin-C, and fibronectin controls mu

275 Also, they move more rapidly on hyaluronic acid than on collagen I or collagen IV.

276 from lipid rafts can directly interact with hyaluronic acid, the C. neoformans ligand.

277 on addition of micromolar concentrations of hyaluronic acid, the resulting fluid viscoelasticity can

278 When osteopontin and hyaluronic acid, the two major ligands of CD44, were tes

279 Furthermore, exogenous hyaluronic acid, through the activation of TLRs and the

280 Our hypothesis is that hyaluronic acid, through TLRs, plays a protective role i

281 Serum hyaluronic acid, tissue inhibitor of metalloproteinase 1

282 d commercial kits to analyze serum levels of hyaluronic acid, tissue inhibitor of metalloproteinases-

283 231 than MCF-7 potentially due to binding of hyaluronic acid to CD44 expressed by MDA-MB-231.

284 Addition of polymers like dextran or hyaluronic acid to surfactant fully reverses inhibition

285 to 0.88) for the most efficacious treatment (hyaluronic acid) to 0.18 (CrI, 0.04 to 0.33) for the lea

286 al permeability to albumin and a decrease in hyaluronic acid uptake in HMP compared to SCS.

287 ials that reported effects of intraarticular hyaluronic acid versus corticosteroids on knee OA were s

288 The pooled effect size for hyaluronic acid was 0.32 (95% confidence interval [CI],

289 Hyaluronic acid was chemically modified with hydroxyethy

290 not MyD88(-/-), TLR4(-/-), COX-2(-/-) mice, hyaluronic acid was protective against DSS-induced colit

291 In wild-type mice, hyaluronic acid was therapeutic in established DSS-induc

292 collagens, glycoproteins, proteoglycans, and hyaluronic acid were detected both in the collagen fiber

293 tin-18 fragments), and hepatic fibrogenesis (hyaluronic acid) were measured.

294 nd to laminin, fibronectin, vitronectin, and hyaluronic acid, which are extracellular matrix elements

295 m subjects with IPF, we found short-fragment hyaluronic acid, which induced migration and proliferati

296 Hyaluronidases degrade hyaluronic acid, which promotes metastasis.

297 A modest elevation in serum hyaluronic acid, which was most pronounced in LPS/RAN-co

298 endocytosis and anthrax toxin lethality, and hyaluronic acid--which interferes with CD44-mediated int

299 abricated with biocompatible and dissolvable hyaluronic acid with a deep cave formed in the basal por

300 lycol)-based copolymer or the polysaccharide hyaluronic acid within microfluidic channels.