ライフサイエンスコーパス: hydra

1 ace during development of the model organism Hydra.

2 n but not in maintenance of the organizer in Hydra.

3 and one orthologous form in flies, worms and hydra.

4 oject aimed at isolating novel peptides from hydra.

5 patterning are continuously active in adult hydra.

6 s play a central role in axial patterning in hydra.

7 tion of HyBMP5-8b, a BMP5-8 orthologue, from hydra.

8 by genes located in the 5S rRNA clusters of Hydra.

9 tion of HyAlx, an aristaless-related gene in hydra.

10 play important roles in axial patterning in hydra.

11 nases (PTKs) in the early-diverging metazoan Hydra.

12 tion-diffusion model for axial patterning in hydra.

13 are important to developmental processes in hydra.

14 metalloproteinase may be multifunctional in hydra.

15 n the endodermal layer of the body column of hydra.

16 verning the maintenance of form in the adult hydra.

17 have long been assumed to control budding in hydra.

18 -box gene, Brachyury, has been isolated from hydra.

19 at a low level throughout the body column of hydra.

20 al role in head as well as axis formation in hydra.

21 nding of the regulation of foot formation in hydra.

22 ts of Pluto's moons Styx, Nix, Kerberos, and Hydra.

23 9 million days of observations of individual Hydra.

24 ding of mechanochemical symmetry breaking in Hydra.

25 freely available at https://github.com/arq5x/Hydra.

26 and regeneration dynamics in planarians and Hydra.

27 ith closely related species of the cnidarian Hydra.

28 identify compounds that affect patterning in Hydra.

29 o components of the SC in the basal metazoan Hydra.

30 h includes anemones, corals, jellyfishes and hydras.

31 Three allelic mutants (hydra 1-1, hydra1-2 and hydra1-3) have been identified,

32 ectodermal epithelium of the model organism hydra (a member of the animal phylum Cnidaria) secrete n

33 age-specific death and reproduction rates in Hydra, a basal metazoan, in a set of experiments compris

34 converting enzyme (ECE) has been cloned from hydra, a freshwater invertebrate that belongs to the sec

35 Hydra, a simple freshwater animal famous for its regener

36 We demonstrate that HYDRA accurately maps diverse classes of SV, including t

37 eady in place in the last common ancestor of Hydra and bilaterians.

38 date on developmental signaling pathways in Hydra and discuss the future directions in which such wo

39 s surrounding the pre-main-sequence stars TW Hydra and HD163296, at distances of about 30 astronomica

40 ricted to the endodermal epithelial cells of hydra and is primarily in the peduncle, the lower end of

41 This plasticity is reflected in the Hydra and Nematostella genomes, which differ to an excep

42 h the publication of the genome sequences of Hydra and Nematostella, whose last common ancestor was t

43 Small satellites Hydra and Nix have higher albedos than expected.

44 ntly simple nerve nets, and the potential of Hydra and other basal metazoans as a model system for ne

45 tain DEATH-domains in basal animals, such as Hydra and primitive chordates, but lack this domain in v

46 ical diameters of ~40 kilometers for Nix and Hydra and ~10 kilometers for Styx and Kerberos.

47 The phylum Cnidaria (sea anemones, corals, hydras and jellyfish) is the likely sister group of the

48 far as the ancestor of diploblasts (corals, hydra, and jellyfish) and triploblasts (bilaterians).

49 , Hym-301 is involved in axial patterning in hydra, and specifically in the regulation of the number

50 We now report that human annexin V and hydra annexin XII reversibly bound to phospholipid vesic

51 Recent X-ray studies of hydra annexin XII showed that it crystallized as a homoh

52 ow that the device can be used to immobilize Hydra, another photophobic regenerative model organism.

53 Although adult hydra are radially symmetrical, expression of both genes

54 characteristics of the hypostome of an adult hydra are similar to those of the organizer region of ve

55 Here we report that Styx, Nix and Hydra are tied together by a three-body resonance, which

56 Cnidarians (corals, anemones, jellyfish and hydras) are a diverse group of animals of interest to ev

57 The expression patterns of the gene in adult hydra, as well as during bud formation, head regeneratio

58 In the freshwater coelenterate, hydra, asexual reproduction via budding occurs at the ba

59 o linear mitochondrial (mt) DNA molecules of Hydra attenuata (phylum Cnidaria, class Hydrozoa, order

60 nic hydra were generated in which a modified hydra beta-catenin gene driven by an actin promoter is c

61 Experimental studies of Hydra between 1736 and 1744 culminated in the discovery

62 Axial patterning of the aboral end of the hydra body column was examined using expression data fro

63 doderm along the entire longitudinal axis of hydra, but at relatively high levels at regions where ce

64 n nematocysts of jellyfish, sea anemones and Hydra, but have lost the most important functional group

65 s study shows that small molecule screens in Hydra can be used to dissect patterning processes.

66 equence from the 5' untranslated region of a Hydra cDNA clone encoding a receptor protein-tyrosine ki

67 in-tyrosine kinase revealed that a number of Hydra cDNAs contain one of two different sequences at th

68 es do not block adhesion or morphogenesis of Hydra cell aggregates.

69 physical mechanisms driving cell sorting in Hydra cell aggregates.

70 ent to explain cell sorting in aggregates of Hydra cells.

71 The tissue dynamics of a hydra consist of a steady state of production and loss o

72 mals that, along with corals, jellyfish, and hydras, constitute the oldest eumetazoan phylum, the Cni

73 analysis of the distribution of RNA from the Hydra Csk gene indicates that it is expressed in most of

74 co-expression is consistent with a role for Hydra Csk in regulation of STK activity.

75 sibility was tested directly by coexpressing Hydra Csk with STK in yeast.

76 Comparison of the expression pattern of Hydra Csk with that of STK, the Hydra Src gene orthologu

77 Fertility rates for Hydra did not systematically decline with advancing age.

78 at recombinant HMMP could digest a number of hydra ECM components such as hydra laminin.

79 have shown that the molecular composition of hydra ECM is similar to that seen in vertebrates and fun

80 is longstanding question by using transgenic Hydra expressing fluorescent proteins and a multiscale e

81 Phylogenetic analyses reveal that the hydra fibrillar collagen genes form a distinct clade tha

82 Four small moons--Styx, Nix, Kerberos and Hydra--follow near-circular, near-equatorial orbits arou

83 Studies with adult intact hydra found that GM6001 could also cause the reversible

84 t drives cell sorting during regeneration of Hydra from cell aggregates is still debated.

85 Our data show that 2,256 Hydra from two closely related species in two laboratori

86 The Hydra genome has been shaped by bursts of transposable e

87 Comparisons of the Hydra genome to the genomes of other animals shed light

88 In addition, surveys of the Nematostella and Hydra genomic projects demonstrate that even distantly r

89 A hydra has a simple structure consisting of a head, body

90 In summary, these studies indicate that hydra has at least one MMP that is functionally tied to

91 The feeding response of Hydra has been well-characterized physiologically and is

92 rent study was designed to determine whether hydra has homologues of these proteinases and, if so, wh

93 Here we report that Hydra has two PIWI proteins, Hydra PIWI (Hywi) and Hydra

94 ellular matrix (mesoglia) of the diploblast, hydra, has characteristics of both a basement membrane a

95 Nix and Hydra have bright surfaces similar to that of Charon.

96 ion pathways in the early-diverging metazoan Hydra have revealed that a number of the well-known deve

97 ase that has an important role in regulating hydra head morphogenesis potentially through its differe

98 Normal hydra head-body proportions were altered by axially graf

99 We have isolated Cngsc, a hydra homologue of goosecoid gene.

100 We have characterized a hydra homologue of the fork head/HNF-3 class of winged-h

101 approach to genomic data aggregation, termed HyDRA (Hybrid Distance-score Rank Aggregation), which co

102 The nonsenescent life history of Hydra implies levels of maintenance and repair that are

103 Crater densities on Nix and Hydra imply surface ages of at least 4 billion years.

104 far longer than the short life expectancy of Hydra in the wild.

105 Hydra is a powerful model system for carrying out studie

106 city of the Hydra mouth and illustrates that Hydra is a powerful system for quantitative biomechanica

107 The cnidarian Hydra is a simple metazoan with well-characterized stem/

108 re we show that the early branching metazoan Hydra is able to modify bacterial quorum-sensing signals

109 Today, Hydra is an important model for studies of axial pattern

110 A new model for oocyte development in Hydra is discussed.

111 As a member of Cnidaria, the body wall of hydra is structurally reduced to an epithelial bilayer w

112 maintenance of axial patterning in the adult hydra is the head activation gradient, i.e. the potentia

113 Although the nervous system of Hydra is traditionally described as a simple nerve net,

114 The Cnidarian, hydra, is an appealing model system for studying the bas

115 he phylum Cnidaria, which includes anemones, hydras, jellyfish, and corals.

116 est a number of hydra ECM components such as hydra laminin.

117 content that parallel simplification of the Hydra life cycle.

118 at essence-based causal explanations emerge, hydra-like, from an inherence heuristic is incomplete.

119 advantage of the availability of transgenic Hydra lines to perform the first dynamical analysis, to

120 arallel and even from other species, such as Hydra littoralis.

121 Here we report the genome of Hydra magnipapillata and compare it to the genomes of th

122 In basal metazoans such as the cnidarians Hydra magnipapillata and Nematostella vectensis, all com

123 al Hcol2, -5, and -6 are highly conserved in Hydra magnipapillata, which also provided preliminary ev

124 tinian cnidarians Nematostella vectensis and Hydra magnipapillata.

125 r have been isolated from Hydra vulgaris and Hydra magnipapillata.

126 ome of nematocysts from the freshwater polyp Hydra magnipapillata.

127 , it appears that developmental processes in Hydra make use of pathways involving a variety of peptid

128 Utilizing a PCR approach, a single hydra matrix metalloproteinase, named HMMP was identifie

129 Hence the expression of these SODs in hydra may have potential as molecular biomarkers for ass

130 Hence the expression of PHGPx mRNA in hydra may have potential use as molecular biomarkers for

131 We previously identified and purified hydra metalloproteinase 1 (HMP-1), a developmentally imp

132 have characterized a new astacin proteinase, hydra metalloproteinase 2 (HMP2) from the Cnidarian, Hyd

133 (TH domain) that is also present in another hydra metalloproteinase, HMP1, in Podocoryne metalloprot

134 derstanding the remarkable plasticity of the Hydra mouth and illustrates that Hydra is a powerful sys

135 rst dynamical analysis, to our knowledge, of Hydra mouth opening and test existing hypotheses regardi

136 Here, we describe Hydra-Multi and measure its accuracy, speed and scalabil

137 Hydra-Multi is written in C++ and is freely available at

138 th Homozygous Familial Hypercholesterolemia [HYDRA]; NCT02226198).

139 linear mitochondrial DNA (mtDNA) molecule of Hydra oligactis (Cnidaria, Hydrozoa)--the first from the

140 We tested HyDRA on a number of gene sets, including autism, breast

141 In addition, the complete cDNA sequences of hydra Pax-A and -B were obtained.

142 the homeodomain and the octapeptide, whereas hydra Pax-A contains neither.

143 says showed that sea nettle Pax-A and -B and hydra Pax-A paired domains bound to a Pax-5/6 site and a

144 Hydra Pax-B contains both the homeodomain and the octape

145 to a Pax-5/6 site and a Pax-5 site, although hydra Pax-B paired domain bound neither.

146 we report that Hydra has two PIWI proteins, Hydra PIWI (Hywi) and Hydra PIWI-like (Hyli), both of wh

147 Hydra PIWI proteins are strictly cytoplasmic and thus li

148 has two PIWI proteins, Hydra PIWI (Hywi) and Hydra PIWI-like (Hyli), both of which are expressed in a

149 common yet sporadic and include some sponge, hydra, planarian, and salamander (i.e., newt and axolotl

150 Sweet Tooth gene is expressed widely in the Hydra polyp, and expression is particularly high in the

151 .e., symmetry breaking) in aggregates of the Hydra polyp.

152 tiation are continuously active in the adult Hydra polyp.

153 Recent work on cysteine-rich domains in Hydra proteins illuminates how evolutionary transitions

154 ding suggested the possibility that mRNAs in Hydra receive leader sequences by trans-splicing.

155 Nix and Hydra rotate chaotically, driven by the large torques of

156 During budding, hydra's asexual form of reproduction, the gene is expres

157 in normal animals and during bud formation, hydra's asexual form of reproduction, were examined.

158 ew axis as part of the development of a bud, hydra's asexual form of reproduction.

159 s contribute to a molecular understanding of Hydra's immortality, indicate an evolutionarily conserve

160 Expression data revealed that Hydra's main bacterial colonizer, Curvibacter sp., respo

161 Alfred Gierer and Hans Meinhardt recognized Hydra's self-organizing properties more than 40 years ag

162 Here, by comparing the transcriptomes of Hydra's stem cells followed by functional analysis using

163 Hydra's unlimited life span has long attracted attention

164 animals, including entamoeba, soybean rust, hydra, sea anemone, nematodes, fruit flies, beetle, sea

165 sects, spiders, mites, scorpions), Cnidaria (Hydra, sea anemones), and Mollusca (oysters) but not in

166 Recent discoveries in the cnidarian Hydra show that components of the innate immune system a

167 Sweet Tooth genes from different species of Hydra shows variation in some of the conserved residues

168 The predicted secondary structures of the Hydra SL RNAs show significant differences from the stru

169 The HyDRA software may be downloaded from: http://web.engr.i

170 erial consortia characteristic for different Hydra species and compared their selective preferences b

171 eptides, the arminins, were detected in four Hydra species, with each species possessing a unique com

172 n pattern of Hydra Csk with that of STK, the Hydra Src gene orthologue, reveals that the two genes ar

173 e (Hyli), both of which are expressed in all Hydra stem/progenitor cells, but not in terminally diffe

174 esults were compared with the similar German HYDRA study to examine whether changes had occurred in d

175 The Hydra Syk gene is expressed in epithelial cells, a site

176 ial cells, a site consistent with a role for Hydra Syk in recognition of foreign cells.

177 Using transgenic Hydra that express green fluorescent protein under the c

178 e for a functional endothelin-like system in hydra that is involved in both muscle contraction and de

179 regated from the soma are characteristics of Hydra that may make nonsenescence feasible.

180 In an adult hydra the head organizer, located in the hypostome, is c

181 In hydra, the head organizer is located in the hypostome, t

182 he characterization of CnOtx, an Otx gene in hydra, thereby providing evidence that Otx genes appeare

183 context of the tissue dynamics of the adult hydra, these three elements controlling axis formation a

184 c gradient that controls axial patterning in hydra, throughout the body column results in extending t

185 we use a MyD88 loss-of-function approach in Hydra to demonstrate that recognition of bacteria is an

186 ent and homeostasis of metazoan animals from Hydra to human.

187 d role of FoxO in controlling longevity from Hydra to humans, and have implications for understanding

188 been studied in a variety of organisms, from Hydra to humans, many of the genes that regulate the abi

189 elopmental processes in animals ranging from Hydra to humans.

190 mong all insulin receptor-like proteins from hydra to humans.

191 entified a eukaryotic mechanism that enables Hydra to specifically modify long-chain 3-oxo-homoserine

192 We have developed an algorithm (HYDRA) to localize SV breakpoints by paired-end mapping,

193 acle, a gene involved in foot development in Hydra, to determine polyp-colony boundaries.

194 To explore this function, we generated a Hydra transcriptome for piRNA mapping.

195 aenorhabditis elegans, Drosophila, planaria, hydra, trypanosomes, fungi and plants, the introduction

196 lated to one another have been isolated from Hydra vulgaris and Hydra magnipapillata.

197 the foot and the head patterning systems in Hydra vulgaris following induction of a foot in close pr

198 xide dismutase (HvEC-SOD) were isolated from Hydra vulgaris in order to understand their expression a

199 or a catalase (HvCatalase) was isolated from Hydra vulgaris using 3'- and 5'- (RLM) RACE approaches.

200 acterization of the NK-2 homolog CnNK-2 from Hydra vulgaris, a freshwater cnidarian.

201 We have investigated oocyte development in Hydra vulgaris, a member of one of the oldest metazoan p

202 Surprisingly, we have found that Hydra vulgaris, a member of the early diverging animal p

203 ndroitin and heparan sulfate compositions of Hydra vulgaris, Drosophila melanogaster, Caenorhabditis

204 We have achieved this with the cnidarian Hydra vulgaris, using calcium imaging of genetically eng

205 ressed during gametogenesis in the cnidarian Hydra vulgaris, we isolated a cDNA encoding Lemon, an RT

206 pted collagenous triple helices (Hcol6) from Hydra vulgaris.

207 rtebrates such as Drosophila melanogaster or Hydra vulgaris.

208 de glutathione peroxidase were isolated from Hydra vulgaris.

209 or protein-tyrosine kinase was identified in Hydra vulgaris.

210 talloproteinase 2 (HMP2) from the Cnidarian, Hydra vulgaris.

211 The freshwater cnidarian Hydra was first described in 1702 and has been the objec

212 Transgenic hydra were generated in which a modified hydra beta-cate

213 In the adult hydra, where axial patterning processes are continuously

214 Treatment of hydra with alsterpaullone, a specific inhibitor of glyco

215 litary species, including the model organism Hydra, with only a few colonial species.

216 imilar to the motif previously identified in hydra, yeast, and other organisms known to signal from t

217 web.engr.illinois.edu/ approximately mkim158/HyDRA.zip.