ライフサイエンスコーパス: hydration water

1 tructure on the dynamics and distribution of hydration water.

2 each component: the macromolecule, ions, and hydration water.

3 the presence of the counterion and not just hydration water.

4 of different protein secondary structures on hydration water.

5 cizes protein structures in a way similar to hydration water.

6 at successfully reproduces the properties of hydration water.

7 macromolecules just follows the dynamics of hydration water.

8 bel placed at the surface and the protons of hydration water.

9 l potentials does reveal a transition in the hydration water, again, no transition in the protein is

10 in line with previous experimental data for hydration water and calculations based on simple assumpt

11 On the other hand, we detected liquid hydration water and strong water-AFP III and water-ubiqu

12 ules, the structural and dynamic behavior of hydration water, and the flexibility and conformation st

13 The dynamics of protein hydration water appear to be very similar in crystal and

14 detailed microscopic view on the dynamics of hydration water around a hydrophobic molecule, tetrameth

15 We show that the structure and dynamics of hydration water around an organic molecule are non-unifo

16 description of the dynamical perturbation of hydration water around green fluorescent protein in solu

17 ercooled water in nanoconfined pores, and in hydration water around proteins.

18 fferences in the dynamics of protein and its hydration water at high temperatures: on the picosecond-

19 e suppression of the protein dynamics by the hydration water at low temperatures appears to be strong

20 ynamics simulations to study the dynamics of hydration water at the surface of fibers formed by the f

21 We demonstrate ordered orientation of the hydration water at the surface of phospholipid bilayers

22 ion of signals corresponding to interfacial (hydration) water at low water content.

23 mperature (approximately 235 K), but protein hydration water avoids this crystallization because each

24 n rates of the hydrogen bonds they form with hydration water, become apparent.

25 ls in different media is the partitioning of hydration water between the enzyme and the bulk solvent.

26 ing the H-bonding/organization status of the hydration waters both in the unbound and the bound state

27 S-G18V: (i) how do the diffusion dynamics of hydration water change as a function of protein crowding

28 dration water, or do populations of bulk and hydration water coexist?

29 We also assess whether hydration water compressibility determined from small co

30 ure, based on average structural features of hydration water, configurational properties of single wa

31 ations have been used to investigate protein hydration water density fluctuations as a function of pr

32 itions and providing a thermodynamic role of hydration water density fluctuations in driving hydropho

33 amics of biological macromolecules and their hydration water depends strongly on the chemical and thr

34 spectroscopy, we simultaneously measured the hydration water dynamics and protein side-chain motions

35 We also found that the hydration water dynamics are always faster than protein

36 lecular dynamics simulations, revealing that hydration water dynamics around the core domain is signi

37 n of the experimentally observed increase in hydration water dynamics around the entire tau fiber.

38 polarization (ODNP) to probe the equilibrium hydration water dynamics at select sites on the surface

39 owder samples are appropriate for discussing hydration water dynamics in native protein environments.

40 The observed increase in hydration water dynamics is suggested to promote fiber f

41 Furthermore, we compare the hydration water dynamics on different polypeptides and l

42 The heterogeneity in the hydration water dynamics suggests that structured protei

43 ODNP reports on site-specific hydration water dynamics within 5-10 A of a label tether

44 we provide insight into the coupling between hydration-water dynamics and atomic motions in intrinsic

45 hought to be governed to a certain extent by hydration-water dynamics, yet it is not known whether th

46 rded due to reduced mobility of the involved hydration water, evident from a 2-fold reduction of the

47 The dynamics of the hydration water exhibits changes at ~ 180-190 K that we

48 the picosecond-to-nanosecond timescale, the hydration water exhibits diffusive dynamics, while the p

49 s decay corresponding to fluctuations of the hydration water, followed by a significant static offset

50 imilar difference appears in the dynamics of hydration water for these biomolecules.

51 an energetic nature and due to desorption of hydration water; for larger hydration it is entropic and

52 aD (+/-0.8 per thousand) of the total gypsum hydration water from the DTIA method are comparable to t

53 drated metal ion and suggests a role for the hydration water in the metal-induced conformational chan

54 re suggested to lead to a compression of the hydration water in the minor groove.

55 wding, the population of this robust surface hydration water increases, while a significant bulk-like

56 emperature range for the tau protein and its hydration water, indicating intimate coupling between th

57 ngth of the hydrogen bond network of surface hydration water is directly modulated on hydrophilic sur

58 Experimental data demonstrate that the hydration water is harmonic at temperatures <~ 180-190 K

59 al variations in thermodynamic properties of hydration water is its equilibrium dynamics spanning pic

60 The diffusion of the GFP hydration water is similar to the behavior of hydration

61 ne --> tetrahydrofuran --> acetonitrile) the hydration water is stripped from the enzyme surface.

62 Hydration water is the natural matrix of biological macr

63 Hydration water is vital for various macromolecular biol

64 rfactant coating are similar to those of the hydration water, leading to the conclusion that the poly

65 o-strong dynamic crossover, the structure of hydration water makes a transition from predominantly hi

66 fiber formation, in particular the role that hydration water might play, remain poorly understood.

67 Detection of the enhanced hydration water mobility around tau fibers is conjecture

68 ne group and the other may be related to the hydration water molecules mainly associated with the pho

69 ons of the same size and charge, anions bind hydration water more strongly.

70 ynamics simulations to explore the nature of hydration water motions at temperatures between 200 and

71 he results provide evidence that protein and hydration-water motions mutually affect and shape each o

72 e mutual influence of biomolecules and their hydration water must be taken into account.

73 r stability, the thermodynamic properties of hydration water must reflect on the properties of the he

74 irect spectroscopic observation of so-called hydration water near a peptide and yields the first quan

75 y with a significant fraction of the surface hydration water network.

76 y, from native to molten globule states, the hydration water networks loosen up, and the protein loca

77 his sudden switch in dynamic behavior of the hydration water on lysozyme occurs precisely at 220 K an

78 t polarity and indicate that the behavior of hydration water on the enzyme surface and in the active

79 Hydration water on the surface of a protein is thought t

80 In comparison with monomeric tau, hydration water on the surface of tau fibers is more mob

81 n occurred generating a single population of hydration water, or do populations of bulk and hydration

82 ructural changes in cell membranes and their hydration water play important functional roles.

83 H1' in the minor groove are consistent with hydration water present that is not observed in the anal

84 ydration water is similar to the behavior of hydration water previously observed for other proteins.

85 Without hydration water, proteins would not fold correctly and w

86 local exclusion of F(-) and Glu(-) from this hydration water, relative to the situation with Cl(-), w

87 We observed three types of hydration water relaxation with distinct time scales, fr

88 gly conflicting range of values reported for hydration water retardation as a logical consequence of

89 lectrostatic fluctuations of the protein and hydration water shells.

90 and solute-water attractive interactions on hydration water structure around spherical clusters of 1

91 MSO was found to effectively destabilize the hydration water structure at the lipid membrane surface

92 The analysis reveals that hydration water suppresses protein motions at lower temp

93 directly to estimate the compressibility of hydration water surrounding proteins.

94 n be used to estimate the compressibility of hydration water surrounding proteins.

95 For hydration water to play a role beyond modulating global

96 dependence on probe length demonstrates that hydration water undergoes subdiffusive motions (tau prop

97 ules prevents the crystallisation of protein hydration water upon cooling.

98 quantification of translational diffusion of hydration water using an emerging tool, (1)H Overhauser

99 s of green fluorescent protein (GFP) and its hydration water using neutron scattering spectroscopy an

100 be triggered by its strong coupling with the hydration water, which also shows a similar dynamic tran

101 phase transition of DPPC concludes that the hydration water with 100-200 ps dynamics displays Arrhen

102 he phonon is coupled to a relaxation mode of hydration water with a single relaxation time of 55 +/-

103 We have also estimated the total amount of hydration water with a typical -9% deviation from experi