ライフサイエンスコーパス: hydrocephalus

1 on, adducted thumbs, spastic paraplegia, and hydrocephalus).

2 d for E cell planar polarity and may prevent hydrocephalus.

3 hat compound genetic ablation of Dvls causes hydrocephalus.

4 luid flow through ciliary beating, can cause hydrocephalus.

5 patient, magnetic resonance imaging revealed hydrocephalus.

6 syndromic ciliopathy including dysosmia and hydrocephalus.

7 f eight displayed learning disability and/or hydrocephalus.

8 uch as Alzheimer disease and normal pressure hydrocephalus.

9 using a rat model of juvenile communicating hydrocephalus.

10 sion of 1 cm or greater, or new or worsening hydrocephalus.

11 % of patients and in 64% of 22 patients with hydrocephalus.

12 of juvenile post-haemorrhagic communicating hydrocephalus.

13 meningitis, seizures, cerebral ischemia and hydrocephalus.

14 nting in Ugandan infants with postinfectious hydrocephalus.

15 , cleft lip with or without cleft palate, or hydrocephalus.

16 t stenosis and the development of congenital hydrocephalus.

17 enotype including ventral body curvature and hydrocephalus.

18 ccumulation of CSF within the brain known as hydrocephalus.

19 progenitors in the pathogenesis of neonatal hydrocephalus.

20 e a serious complication in the treatment of hydrocephalus.

21 st common indication for CT in children with hydrocephalus.

22 n be an initiating cause of noncommunicating hydrocephalus.

23 evelopment and its dysregulation may lead to hydrocephalus.

24 ilibrium syndrome 2, cause severe congenital hydrocephalus.

25 nge in neuronal AbetaPP expression following hydrocephalus.

26 Administration (FDA)-approved drugs to treat hydrocephalus.

27 duced hippocampal long-term potentiation and hydrocephalus.

28 d on controls and after 2, 6 and 10 weeks of hydrocephalus.

29 complexes that affect brain development and hydrocephalus.

30 uch as brainstem compression and obstructive hydrocephalus.

31 phalus as well as idiopathic normal pressure hydrocephalus.

32 , and mice with Hydin defects develop lethal hydrocephalus.

33 renchymal compared with meningeal lesions or hydrocephalus.

34 th leptomeningeal, and 0/3 for patients with hydrocephalus.

35 NM II-B-ablated mice seem to be the cause of hydrocephalus.

36 e motor-impaired NM II-B, which also rescues hydrocephalus.

37 hat all transgenics expressing Ro1 developed hydrocephalus.

38 cles and destruction of brain tissue, due to hydrocephalus.

39 athogenesis of both juvenile and adult onset hydrocephalus.

40 encephalic cysts, periventricular cysts, and hydrocephalus.

41 cognate proteins to delineate their role in hydrocephalus.

42 sta1, Xdh, Tnf, and Tfpi-2, can be linked to hydrocephalus.

43 or an autosomal recessive form of congenital hydrocephalus.

44 rusion is associated with the development of hydrocephalus.

45 A few mutant mice developed hydrocephalus.

46 sociated with the presence or development of hydrocephalus.

47 disease, agenesis of the corpus callosum and hydrocephalus.

48 ormalities, skeletal patterning defects, and hydrocephalus.

49 s in 83% of animals and were associated with hydrocephalus.

50 with intraventricular haemorrhage and acute hydrocephalus.

51 g is important in the production of X-linked hydrocephalus.

52 Gs, and may reflect level of brain injury in hydrocephalus.

53 ycystic kidney disease, nephronophthisis and hydrocephalus.

54 enes that have been previously implicated in hydrocephalus.

55 Twenty-six fetuses (45%) had prenatal hydrocephalus.

56 of an enhancing suprasellar mass lesion and hydrocephalus.

57 rupting cerebrospinal fluid flow and causing hydrocephalus.

58 may help in the diagnosis and prevention of hydrocephalus.

59 ass effect/herniation, 3) infarction, and 4) hydrocephalus.

60 levated HB-EGF can elicit VEGF induction and hydrocephalus.

61 sociated with left ventricular uncompensated hydrocephalus.

62 emorrhaging branchial arch blood vessels and hydrocephalus.

63 acranial hemorrhage without midline shift or hydrocephalus.

64 d the development of fetal non-communicating hydrocephalus.

65 n, enlargement of the lateral ventricles and hydrocephalus.

66 obtained from patients with normal pressure hydrocephalus.

67 can result in abnormal CSF accumulation and hydrocephalus.

68 ng glycine accumulation, early lethality and hydrocephalus.

69 mice exhibit early vision loss and die from hydrocephalus.

70 (1.2%), club foot (1%), hypospadias (0.6%), hydrocephalus (0.6%), cleft lip or palate (0%), and obst

71 yes with glaucoma (4.6%) (3 uveitis, 1 prior hydrocephalus, 1 uveitis and pars plana vitrectomy, and

72 sitivity and specificity, respectively, were hydrocephalus (100% and 100%), clubfoot (100% and 99.8%)

73 dian age, 43 years) with chronic obstructive hydrocephalus, 12 of whom went on to undergo ETV, were i

74 Acute hydrocephalus (13.6% vs 7.4%; p < 0.001) and mass effect

75 Hydrocephalus (17.4%) was the commonest MRI finding.

76 included raised intracranial pressure (42%), hydrocephalus (30%), neurological deficits (27%; 6% deve

77 , 51.9-100.0), fever (89.8%, 79.8-95.2), and hydrocephalus (86.1%, 68.6-94.6).

78 ase, results in aberrant CSF circulation and hydrocephalus, a common disorder of the CNS.

79 Pard3 depletion results in hydrocephalus, a defect often associated with abnormal c

80 in both, the Reelin pathway and Lis1 exhibit hydrocephalus, a phenotype that is suppressed by mutatio

81 L1cam knockout (L1(KO)) mice have hydrocephalus, a small cerebellum, hyperfasciculation of

82 Mendelian forms of hydrocephalus account for a small fraction of the geneti

83 Hydrocephalus also occurs in some mutants.

84 In Wistar polycystic kidney rats with hydrocephalus, alteration of migratory trajectory is det

85 port that loss of pericytic laminin leads to hydrocephalus and BBB breakdown in a small percentage (1

86 e of anterior cerebral hemisphere to divide, hydrocephalus and cleft palate which have been observed

87 onal defects in brain development, including hydrocephalus and cortical thinning.

88 dentifying molecular mechanisms for neonatal hydrocephalus and developing noninvasive treatment modal

89 The newborn Lgl1(-/-) pups develop severe hydrocephalus and die neonatally.

90 ofound growth retardation with communicating hydrocephalus and early mortality.

91 ng brain enlargement, cortical malformation, hydrocephalus and epilepsy, with phenotypic severity dep

92 f recessive mutations in familial congenital hydrocephalus and expands the locus heterogeneity of thi

93 ontributing to this Rnd3-deficiency-mediated hydrocephalus and found that Rnd3 is a regulator of Notc

94 The mice developed hydrocephalus and grossly dilated lateral ventricles, wi

95 and therapeutic options for various forms of hydrocephalus and ideopathic intracranial hypertension.

96 and therapeutic options for various forms of hydrocephalus and idiopathic intracranial hypertension.S

97 ons associated with chronic airway diseases, hydrocephalus and infertility.

98 that Dlg5(-/-) mice develop fully penetrant hydrocephalus and kidney cysts caused by a deficiency in

99 y ciliary dyskinesia phenotypes that include hydrocephalus and laterality malformations.

100 ility resulted in pronephric cyst formation, hydrocephalus and left-right asymmetry defects.

101 In addition, cdc42 knockdown led to hydrocephalus and loss of photoreceptor cilia.

102 OCRL whose deficiencies are associated with hydrocephalus and Lowe oculocerebrorenal syndrome, respe

103 tions in the human L1CAM gene cause X-linked hydrocephalus and MASA (Mental retardation, Aphasia, Shu

104 n cerebrospinal fluid of human neonates with hydrocephalus and may be a target for peroxynitrite modi

105 rated primitive reflexes, epilepsy, acquired hydrocephalus and microcephaly, neurodevelopmental delay

106 nse morpholinos (MOs) led to bent body axes, hydrocephalus and oedema.

107 dings show that Dlg5 is causally involved in hydrocephalus and renal cysts and reveal that targeted m

108 onal Cep290(gt/gt) mouse that survives shows hydrocephalus and severely cystic kidneys.

109 as diseases including cystic kidney disease, hydrocephalus and situs inversus.

110 s with fever and headache that progressed to hydrocephalus and status epilepticus necessitating a med

111 ve control cohort consisted of patients with hydrocephalus and suspected intracranial hypertension (n

112 hort (33% female), 48.9 (83.8) months in the hydrocephalus and suspected intracranial hypertension co

113 tudy the pathophysiology of various forms of hydrocephalus and to design therapeutic strategies in re

114 ted tomographic imaging revealed obstructive hydrocephalus, and a ventriculoperitoneal shunt was plac

115 pkd2 morphant phenotypes, pronephric cysts, hydrocephalus, and body curvature.

116 g morpholinos (MOs) caused pronephric cysts, hydrocephalus, and body curvature.

117 ebrafish resulted in ventral body curvature, hydrocephalus, and cystic kidneys, similar to the effect

118 rain abnormalities (occipital encephalocele, hydrocephalus, and Dandy Walker-type cerebellar anomalie

119 hydin, a protein that, when mutated, causes hydrocephalus, and defined a unique role for hydin in ci

120 actures, craniosynostosis, ocular proptosis, hydrocephalus, and distinctive facial features.

121 BS knockout models: no overt obesity, severe hydrocephalus, and elevated blood pressure (shared by so

122 y, cerebellar hypoplasia, lissencephaly with hydrocephalus, and fetal akinesia deformation sequence (

123 isease, including aberrant neuron migration, hydrocephalus, and malformations of the anterior and pos

124 n, GM hemorrhage can lead to cerebral palsy, hydrocephalus, and mental retardation.

125 ) was observed, with almost complete agyria, hydrocephalus, and multifocal dystrophic calcifications

126 opathy phenotypes, including axis curvature, hydrocephalus, and pronephric cysts, and disrupts multic

127 udy of conditions such as Alzheimer disease, hydrocephalus, and pseudotumor cerebri.

128 dney cysts, randomized left-right asymmetry, hydrocephalus, and rod outer segment defects, suggesting

129 Early complications include rebleeding, hydrocephalus, and seizures.

130 re pronounced phenotypes, including runting, hydrocephalus, and shortened life span, recapitulating t

131 haracterized by sinusitis, male infertility, hydrocephalus, and situs inversus.

132 Patterns of brain parenchyma, hydrocephalus, and so-called middle cerebral artery (MCA

133 are crucial in the pathogenesis of neonatal hydrocephalus, and we identify new therapeutic targets f

134 herapy, pre-existing endocrine deficiencies, hydrocephalus, and younger age at CRT (< 5 years) were p

135 ycystin-2, whose ablation is associated with hydrocephalus are colocalized to the ependymal cilia.

136 factors that contribute to the initiation of hydrocephalus are poorly understood.

137 JCV in aseptic meningitis and in idiopathic hydrocephalus are warranted.

138 ntricles and a minority developed idiopathic hydrocephalus as adults, but none of the transgenic mice

139 The classic understanding of hydrocephalus as the result of obstruction to bulk flow

140 new therapies and work toward understanding hydrocephalus as well as idiopathic normal pressure hydr

141 esenting a phenotypic spectrum of congenital hydrocephalus associated with 5 recessive alleles.

142 t of certain types of neonatal and childhood hydrocephalus associated with hemorrhages and infections

143 ow-up time (OR, 1.10; 95% CI, 1.02 to 1.18), hydrocephalus at diagnosis (OR, 1.77; 95% CI, 1.09 to 2.

144 t in 22.8% (566/2,486) of examinations, with hydrocephalus being most common (11.5% [286/2,486]).

145 rain magnetic resonance images (MRIs) showed hydrocephalus, bilateral frontal polymicrogyria, abnorma

146 All double transgenics developed hydrocephalus by postnatal day 15, whereas single-transg

147 also disrupts ependymal cilia, resulting in hydrocephalus by postnatal day 4.

148 een cilia dysfunction and the development of hydrocephalus by using the Tg737orpk mutants.

149 Hydrocephalus can also be acquired, mostly from patholog

150 Hydrocephalus caused by mutations in hydin likely involv

151 ound to be significantly elevated in preterm hydrocephalus cerebrospinal fluid (P<0.02), but correlat

152 In hydrocephalus, cerebrospinal fluid (CSF) builds up in th

153 aemorrhagic and other forms of communicating hydrocephalus, cerebrospinal fluid flow and drainage is

154 Although tumor site, hydrocephalus, chemotherapy, and cranial radiation thera

155 ic fistula, undescended testes, hypospadias, hydrocephalus, cleft lip or palate, and club foot.

156 c fistulas, undescended testes, hypospadias, hydrocephalus, cleft lip/palate, and clubfoot) was deter

157 the mice died, by 4weeks after birth, severe hydrocephalus could also be seen.

158 splay significant abnormalities that include hydrocephalus, defective myelination and reduced lifespa

159 xis curvature, organ laterality defects, and hydrocephalus-defects that could be rescued by expressio

160 e minority of Cep290(ko/ko) mice that escape hydrocephalus demonstrate progressive kidney pathology.

161 tor of Yap that can cause fetal haemorrhagic hydrocephalus, deregulates Yap in the developing aqueduc

162 the mechanistic role of neuroinflammation in hydrocephalus development is unclear.

163 Inhibition of Notch activity rescued the hydrocephalus disorder in the mutant animals.

164 report a role of Rnd3 in the pathogenesis of hydrocephalus disorder.

165 f 5-day-old H-Tx rats; these animals develop hydrocephalus due to closure of their cerebral aqueduct

166 t and subsequent formation of triventricular hydrocephalus during early postnatal brain development.

167 nt role in cell adhesion, thereby preventing hydrocephalus during mouse brain development.

168 There were no new lesions, worsening hydrocephalus, evidence of increased intracranial pressu

169 ain with diffuse parenchymal calcifications, hydrocephalus ex vacuo, and cerebellar hypoplasia.

170 cytes during early postnatal life results in hydrocephalus formation and additional defects in brain

171 NF-kappaB activation is sufficient to induce hydrocephalus formation and provides a potential mechani

172 requent association of neuroinflammation and hydrocephalus formation during brain development, namely

173 he higher incidence of aqueduct stenosis and hydrocephalus formation in patients with ciliary defects

174 Hydrocephalus formation is a frequent complication of ne

175 In this animal model, hydrocephalus formation is specifically induced during a

176 of collagen XVIII/endostatin predisposes to hydrocephalus formation.

177 date genes in the pathogenesis of congenital hydrocephalus, gene arrays were utilized to analyze tran

178 d genes and inheritance paradigms underlying hydrocephalus, grouping causal loci into functional modu

179 Hydrocephalus has many causes.

180 Studies of syndromic hydrocephalus have led to the identification of >100 cau

181 resulted in complete penetrance of perinatal hydrocephalus (HC) and severe polycystic kidney disease

182 everal ciliated organs, including the brain (hydrocephalus), heart (cardiac edema), and kidney (disor

183 f embryolethality before gestational day 11, hydrocephalus, hermaphroditism, and cystic ovaries.

184 hm for detecting hemorrhage, mass effect, or hydrocephalus (HMH) at non-contrast material-enhanced he

185 o1 animals maintained on dox did not develop hydrocephalus; however, if taken off doxycycline at wean

186 cts have been identified in animal models of hydrocephalus; however, the relationship between HB-EGF

187 hernia or hydrocele [adult and paediatric]), hydrocephalus, hypospadias, injuries or wounds, neck mas

188 in Wnt1 cell lineages results in congenital hydrocephalus, implicating huntingtin for the first time

189 aseptic meningitis resulting in symptomatic hydrocephalus in a human immunodeficiency virus-seronega

190 ch we propose as a novel cause of congenital hydrocephalus in addition to its suggested role in corti

191 indicating that Ro1 expression also induces hydrocephalus in adults.

192 s suppressed Ro1 expression and the onset of hydrocephalus in double-transgenic offspring.

193 s cystic kidney disease, male sterility, and hydrocephalus in humans and model vertebrates.

194 and HYDIN is a strong candidate for causing hydrocephalus in humans.

195 We conclude that hydrocephalus in hydin mutants is caused by a central pa

196 Postinfectious hydrocephalus in infants is a major health problem in su

197 de that decorin prevented the development of hydrocephalus in juvenile rats by blocking transforming

198 ricular size demonstrated the development of hydrocephalus in kaolin-injected rats but also revealed

199 Our results show that hydrocephalus in mice lacking htt in Wnt1 cell lineages

200 , we describe the development of obstructive hydrocephalus in mice that are null for Wrp (Srgap3).

201 Mutations in Hydin cause hydrocephalus in mice, and HYDIN is a strong candidate f

202 There were five cases of unexplained hydrocephalus in not-recently-ruptured aneurysms in the

203 ere the most common etiologies of congenital hydrocephalus in our cohort (19% and 26%, respectively).

204 Its dysregulation leads to hydrocephalus in postnatal mouse brains.

205 Hydrocephalus in the elderly rat, therefore, can induce

206 BBB disruption always goes hand-in-hand with hydrocephalus in these mutants, and neither symptom is o

207 re found to be altered in the development of hydrocephalus in this model.

208 We found that hydrocephalus in this mouse model is caused by aberrant

209 ns in eight, parenchymal lesions in six, and hydrocephalus in two.

210 This study discovered a new model of hydrocephalus in which the rate of pathogenesis can be c

211 roles of primary cilia in brain patterning, hydrocephalus incidence, and cleft palate.

212 One-year-old male Sprague-Dawley rats had hydrocephalus induced by cisternal kaolin injection.

213 The human-specific gene hydrocephalus-inducing 2, HYDIN2, was generated by a 364

214 re, we show for the first time that hydin, a hydrocephalus-inducing gene product whose mutation impai

215 ects induced by treatment, such as seizures, hydrocephalus, infarcts, and neuroinjury.

216 duals treated for idiopathic normal pressure hydrocephalus (iNPH), 37 patients clinically diagnosed w

217 Hydrocephalus is a common disorder of cerebral spinal fl

218 Hydrocephalus is a common neurological disorder that lea

219 Congenital hydrocephalus is an important birth defect, the genetics

220 lo-peritoneal shunt failure in children with hydrocephalus is coherent with the valid principles of r

221 cause Mendelian diseases in which congenital hydrocephalus is the main or sole clinical feature, 2 X-

222 Hydrocephalus is the most common developmental disabilit

223 however, the relationship between HB-EGF and hydrocephalus is unclear.

224 lluminated numerous pathways associated with hydrocephalus, it has also highlighted the fact that the

225 However, in persons with West syndrome or hydrocephalus, it might be impossible to unravel whether

226 associated with ciliary dysfunction, such as hydrocephalus, kidney cysts and situs inversus.

227 polycystin 2 knockdown induces kidney cysts, hydrocephalus, left/right asymmetry defects, and strong

228 One parenchymal and two hydrocephalus lesions, however, developed after diagnosi

229 s and NSCs-derived ependymal cells developed hydrocephalus-like characteristics, including enlarged v

230 the organismal level, Rad50(+/46) exhibited hydrocephalus, liver tumorigenesis, and defects in primi

231 r (acquired, preterm birth, West syndrome or hydrocephalus), making differentiation between acquired

232 Homozygous mice have PCD characterized by hydrocephalus, male infertility, and mucus accumulation.

233 operative morbidity due to the production of hydrocephalus, mass effect, and their typical location a

234 e patients and patients with normal pressure hydrocephalus may have a higher risk of developing glauc

235 luated after 7 to 14 days postinfection, and hydrocephalus, micromyelia, and muscular loss were obser

236 Congenital hydrocephalus, most commonly involving aqueduct stenosis

237 he megalencephaly-polymicrogyria-polydactyly-hydrocephalus (MPPH) syndrome.

238 nd megalencephaly-polymicrogyria-polydactyly-hydrocephalus (MPPH) syndromes are sporadic overgrowth d

239 Idiopathic normal pressure hydrocephalus (NPH) remains both oversuspected on clinic

240 demonstrated to be lower in normal pressure hydrocephalus (NPH) than in normal controls.

241 unt-responsive patients with normal-pressure hydrocephalus (NPH; mean age, 75 years; age range, 58-87

242 wn in zebrafish replicates all WWS features (hydrocephalus, ocular defects, and muscular dystrophy),

243 che history, and initial evaluation revealed hydrocephalus of unclear etiology.

244 Atxn1L(-/-) mice have hydrocephalus, omphalocele, and lung alveolarization def

245 ted anomaly, in 1 case it was accompanied by hydrocephalus only, in the remaining 6 cases RES was an

246 e posterior fossa oedema causing obstructive hydrocephalus or brainstem compression.

247 c meningitis in immunocompetent individuals, hydrocephalus or chorioretinitis in fetal infection, or

248 eletion using Nestin-CreER(T2) did not cause hydrocephalus or prevent the formation of ciliated epend

249 No surgery-related mortality, hydrocephalus, or superficial cerebral hemosiderosis occ

250 utation that caused VACTERL association with hydrocephalus, or VACTERL-H.

251 a defects including abnormal body curvature, hydrocephalus, otolith defects and abnormal renal, head

252 th meningeal versus parenchymal lesions, and hydrocephalus (P=0.015).

253 bearing functional ties to a reported mouse hydrocephalus phenotype associated with Ccdc85c.

254 Posthemorrhagic hydrocephalus (PHH), an expansion of the cerebral ventri

255 polycystic kidney disease, nephronophthisis, hydrocephalus, polydactyly, situs inversus, retinal dege

256 f permanent shunt dependency for aresorptive hydrocephalus post-ICH.

257 renology, localization of cortical function, hydrocephalus, psychoanalysis, aphasia, dementia and dep

258 ed with worse intellectual outcome; however, hydrocephalus requiring CSF diversion and mutism differe

259 mas can cause life-threatening symptoms--eg, hydrocephalus, requiring surgery.

260 Four anatomical patterns of hydrocephalus secondary to congenital Toxoplasma gondii

261 traventricular extension of haemorrhage with hydrocephalus, seizures, venous thrombotic events, hyper

262 been shown to be associated with congenital hydrocephalus, severe intellectual disability, aphasia,

263 nvolving Ugandan infants with postinfectious hydrocephalus showed no significant difference between e

264 er DALY), general surgery ($82.32 per DALY), hydrocephalus surgery ($108.74 per DALY), and ophthalmic

265 h large ventricles, causing macrocephaly and hydrocephalus suspicion, and all cases exhibited partial

266 se megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome (MPPH, OMIM 603387).

267 ospinal fluid (CSF) of children with TBM and hydrocephalus taken on admission and over 3 weeks were a

268 e expression in a congenital model of rodent hydrocephalus that are occurring locally in the area sur

269 of the B(a*)/B(a*) mice showed evidence for hydrocephalus that is always found in B(-)/B(-) mice.

270 A subset of patients developed hydrocephalus that required cerebrospinal fluid (CSF) di

271 At primary diagnosis, he presented with hydrocephalus that required ventriculoperitoneal shunt p

272 mice in an effort to develop a new model of hydrocephalus that will further our understanding of the

273 To determine if defects in Hydin cause hydrocephalus through a mechanism involving cilia, we co

274 stenosis, lumbar disc herniation, childhood hydrocephalus, trauma mortality, and the occurrence of s

275 points; altered mental status, three points; hydrocephalus, two points; infratentorial PICH, two poin

276 e sex, as well as clinical variables such as hydrocephalus, use of radiotherapy and radiotherapy dose

277 or children that have received treatment for hydrocephalus varies.

278 or association with intracranial evidence of hydrocephalus, vasogenic edema, central venous thrombosi

279 fetal ultrasound indicates severe symptoms (hydrocephalus, ventricular dilation), treatment is conti

280 DR (0.85 vs. 0.63; P<0.001), posthemorrhagic hydrocephalus was associated with shallower cup (331 vs.

281 West syndrome and/or hydrocephalus was identified in 21 patients (7%), and in

282 Hydrocephalus was induced by a single basal cistern inje

283 6q22.2 and implicated in autosomal recessive hydrocephalus was inserted into the 1q21.1 region during

284 backcrossed on the C57BL/6 strain, a severe hydrocephalus was observed and after several generations

285 (6%) both an acquired cause and West and/or hydrocephalus was present.

286 Although the etiology of hydrocephalus was studied before, the effects of ethanol

287 ary cilia without the confounding effects of hydrocephalus, we stereotaxically targeted elimination o

288 MCA pseudofeeders and hydrocephalus were risk factors for both severe cardiac

289 PHP-RC phenotypes, including renal cysts and hydrocephalus, which is rescued by a Wnt inhibitor and b

290 y thus be one determining factor for chronic hydrocephalus, which leads to atrophy of subcortical str

291 mozygous mutants die perinatally from severe hydrocephalus, while mice on other backgrounds have an a

292 enetic deletion developed severe obstructive hydrocephalus with enlargement of the lateral and third

293 Finally, the hydrocephalus with hop gait (hyh) mouse, which harbors a

294 The hyh (hydrocephalus with hop gait) mouse shows a markedly smal

295 The mouse alpha-SNAP mutant hyh (hydrocephalus with hop gait) shows enhanced binding and

296 Here we show that alpha-SNAP hypomorph, hydrocephalus with hopping gait, Napa(hyh/hyh) mice harb

297 Hydrocephalus with shunt placement was associated with i

298 proximately 50% develop lethal communicating hydrocephalus with striking dilation of the lateral, thi

299 the genetic etiology of familial congenital hydrocephalus with the assumption that these cases repre

300 ent knockdown of hrg-1 in zebrafish leads to hydrocephalus, yolk tube malformations and, most strikin