ライフサイエンスコーパス: hydroformylation

1 o larger reaction schemes, as in homogeneous hydroformylation.

2 onversion of ethylene to propanal via tandem hydroformylation.

3 e formed selectively under the conditions of hydroformylation.

4 acts as a proton shuttle to enable transfer hydroformylation.

5 ht the complex kinetics of Rh(BDP) catalyzed hydroformylation.

6 med to be intermediates in rhodium-catalyzed hydroformylation.

7 s that are generally assumed to be active in hydroformylation.

8 om the same alkene 4 by catalytic asymmetric hydroformylation.

9 f regioselectivity and enantioselectivity in hydroformylation.

10 onds to the substrate, allowing for directed hydroformylation.

11 ure is largely focused on polymerization and hydroformylation.

12 noxide and hydrogen) and ethylene via tandem hydroformylation.

13 or improvement is greater than in the mature hydroformylation.

14 n the activity and selectivity of asymmetric hydroformylation (AHF) catalysts.

15 L1 and L2 in the highly selective asymmetric hydroformylation (AHF) of the challenging substrate 2,3-

16 - and enantioselectivities in the asymmetric hydroformylation (AHF) of three heterocyclic olefins.

17 Asymmetric hydroformylation (AHF) of Z-enamides and Z-enol esters p

18 Four different Rh-catalyzed asymmetric hydroformylation (AHF) tandem reactions have been develo

19 nd Ru3(CO)12 or Ru(methylallyl)2(COD) direct hydroformylation and hydrogenation of alkenes to alcohol

20 kinetics of phosphine-free cobalt-catalyzed hydroformylation and hydrogenation of alkenes.

21 he principles of tandem catalysis related to hydroformylation and represents a key step toward the ra

22 re highly active and selective in asymmetric hydroformylation applications.

23 the substrate ligand interaction is dynamic, hydroformylations are catalytic in ligand and do not req

24 (e.g., CO/alkene copolymerization and alkene hydroformylation) are considered.

25 tivity and enantioselectivity of aryl alkene hydroformylation as catalyzed by rhodium complexes of th

26 By analogy with hydroformylation, bulkier ligands ought to be tested in

27 ), which were subsequently used for ethylene hydroformylation catalysed by the nearby Pt-SiO(2) inter

28 Exposure of tethered BDPs to the hydroformylation catalyst precursor, Rh(acac)(CO)2, yiel

29 (1) Hydroformylation catalysts, particularly some recently p

30 inyl esters via a cascade reaction including hydroformylation, condensation with a primary amine, and

31 Experiments under hydroformylation conditions confirm the formation of the

32 nes, alkynes, and dienes in fewer steps than hydroformylation does, the latter has some advantages at

33 on seems to have an advantage as compared to hydroformylation due to the high activity and selectivit

34 was converted to the dimethyl acetal 25 via hydroformylation followed by aldehyde protection.

35 te and BINAPHOS, whose utility in asymmetric hydroformylation has been previously demonstrated.

36 covalently attached to the substrate during hydroformylation; however, similar to traditional asymme

37 yields catalysts for immobilized asymmetric hydroformylation (iAHF) of prochiral alkenes.

38 (2) Hydroformylation is proven, commercial.

39 Hydroformylation of (E)- and (Z)-beta-deuteriostyrene at

40 is the first example in which the asymmetric hydroformylation of 1 is both regio- and enantioselectiv

41 The efficient hydroformylation of 1,1,3-trisubstituted allenes is acco

42 he highly enantioselective rhodium-catalyzed hydroformylation of 1,1-disubstituted olefins has been d

43 However, optimal regio- and enantioselective hydroformylation of 2,3-dihydrofuran (up to 3.8:1 alpha-

44 ng high enantioselectivity in the asymmetric hydroformylation of allyl cyanide and the conjugate addi

45 to be the best overall ligand for asymmetric hydroformylation of allyl cyanide with up to 80% ee and

46 ral auxiliary and screened in the asymmetric hydroformylation of allyl cyanide.

47 he aldehyde is obtained with 97% ee from the hydroformylation of allyl silyl ethers.

48 Hydroformylation of alpha-deuteriostyrene at 80 degrees

49 st catalytic diastereo- and enantioselective hydroformylation of cyclopropenes was demonstrated.

50 as well as the regio- and diastereoselective hydroformylation of disubstituted olefins is reported.

51 The directed hydroformylation of disubstituted olefins occurs under m

52 Hydroformylation of either 2,3- or 2,5-dihydrofuran yiel

53 r the application in Rh-catalyzed asymmetric hydroformylation of heterocyclic olefins.

54 , has been applied to the diastereoselective hydroformylation of homoallylic alcohols to afford delta

55 The desymmetrizing hydroformylation of internal alkenes derived from dihydr

56 Furthermore, 85% ee was obtained in the hydroformylation of N-acetyl-3-pyrroline (5) with except

57 aphospholane ligands catalyze the asymmetric hydroformylation of N-vinyl carboxamides, allyl ethers,

58 rms very well in the Rh-catalyzed asymmetric hydroformylation of other heterocyclic olefins.

59 s has been achieved through enantioselective hydroformylation of PMP-protected allylic amines.

60 hodium bis(diazaphospholane) (BDP) catalyzed hydroformylation of styrene is sensitive to CO concentra

61 (2) and CO pressure on n:i, % ee, and TOF of hydroformylation of styrene was investigated.

62 Regio- and enantioselective hydroformylation of styrenes is attained upon embedding

63 nd results in unprecedented selectivities in hydroformylation of terminal and internal alkenes functi

64 that promotes branch and diastereoselective hydroformylation of terminal olefins as well as the regi

65 es involve (i) an extremely linear-selective hydroformylation of the terminal alkene moiety of a dehy

66 Rh-bisdiazaphospholane catalysts enable hydroformylation of these challenging disubstituted subs

67 applied to the rhodium-catalyzed asymmetric hydroformylation of unfunctionalized internal alkenes.

68 ise disfavored beta-aldehyde products in the hydroformylation of vinyl 2- and 3-carboxyarenes, with c

69 and their application in the regioselective hydroformylation of vinyl and allyl arenes bearing an an

70 ieved in the rhodium-catalyzed isomerization-hydroformylations of internal olefins compared with its

71 been achieved in the Rh-catalyzed asymmetric hydroformylations of styrene derivatives and vinyl aceta

72 The first time application of hydroformylation on olefinic derivatives of isosorbide a

73 ative application of the sequence asymmetric hydroformylation/oxidation/alkyne hydroacyloxylation tha

74 In hydroformylation, phosphorus-based directing groups have

75 otocols relied on a rhodium catalyzed linear hydroformylation process, the alternative approach was b

76 tures representing the various stages of the hydroformylation reaction of propene in supercritical CO

77 the directing group strategy accelerates the hydroformylation reaction such that the reaction is perf

78 of acyl formation and acyl hydrogenolysis in hydroformylation reactions.

79 ion, hydrogenations, electro-oxidations, and hydroformylation reactions.

80 d for hydroaminomethylation beyond classical hydroformylation/reductive amination.

81 These hydroformylation results were compared with those of two

82 on technology will directly compete with the hydroformylation route.

83 ns reveals that the ethylene present for the hydroformylation step slows down initial methanol decomp

84 O)2(BDP)] [BDP = bis(diazaphospholane)] with hydroformylation substrates vinyl acetate, allyl cyanide

85 dies on the mechanism of a rhodium-catalyzed hydroformylation that is selective for branched aldehyde

86 The application of hydroformylation to the synthesis of quaternary carbon c

87 decomposition are poised to directly undergo hydroformylation upon migration from one catalytic inter

88 ) Hydroesterification requires pure CO while hydroformylation uses syngas, a mixture of CO and H2.

89 The product of allyl cyanide hydroformylation using (R,R)-11 was subsequently transfo

90 ve production of aldehyde through the tandem hydroformylation was also observed on propylene and 1-bu

91 on a cyclohydrocarbonylation (CHC) driven by hydroformylation was set up toward the efficient diaster

92 1,2-disubstituted alkenes undergo effective hydroformylation with 89-97% ee and complete conversion

93 Asymmetric hydroformylation with Rh-bisdiazaphospholane catalyst in

94 yl benzyl ether followed by enantioselective hydroformylation yields the beta(3)-aminoaldehyde with 7