ライフサイエンスコーパス: hydrogenosome

1 organelle involved in energy metabolism, the hydrogenosome.

2 lated proteins (DRPs) in the division of the hydrogenosome.

3 an with POR of bacteria and the T. vaginalis hydrogenosome.

4 volved in carbohydrate metabolism called the hydrogenosome.

5 ors an evolutionarily related organelle, the hydrogenosome.

6 chondrion-related organelles (MROs), such as hydrogenosomes.

7 processing peptidase (MPP) and localizes to hydrogenosomes.

8 verse effects on the number and integrity of hydrogenosomes.

9 al AAC can be targeted into the membranes of hydrogenosomes.

10 rgets its POR to anaerobic organelles called hydrogenosomes.

11 demonstrated that this protein localizes to hydrogenosomes.

12 ait, whether it be a 'real' mitochondrion, a hydrogenosome, a mitosome or a few genes left behind fro

13 mitochondrial ancestry of the Neocallimastix hydrogenosome and sheds light upon the stepwise process

14 derlying protein targeting and biogenesis of hydrogenosomes and mitochondria are similar, consistent

15 and membrane protein-targeting machinery of hydrogenosomes and mitochondria have a common evolutiona

16 Matrix proteins of mitochondria, hydrogenosomes and mitosomes are typically targeted and

17 Using purified hydrogenosomes and radiolabeled hydrogenosomal precursor

18 Thus, our data demonstrate that fungal hydrogenosomes and yeast mitochondria use the same pathw

19 ODC results in growth arrest, destruction of hydrogenosomes, and decreased amounts of hydrogenosomal

20 t that yeast mitochondria and Neocallimastix hydrogenosomes are but two manifestations of the same fu

21 Like mitochondria, hydrogenosomes are double-membrane bounded organelles th

22 Hydrogenosomes are hydrogen-producing organelles that ar

23 Hydrogenosomes are, however, markedly different from mit

24 sively by substrate-level phosphorylation in hydrogenosomes, as opposed to oxidative phosphorylation

25 roximately 47 kDa metallopeptidase, from the hydrogenosome-bearing, unicellular eukaryote Trichomonas

26 TvCyP1 was primarily localized to the hydrogenosomes by immunofluorescence assay, but it was a

27 We show here that hydrogenosomes contain heat shock proteins, Hsp70, Hsp60

28 Similar to classic mitochondria, hydrogenosomes contain the enzyme catalyzing the only re

29 now identified genes from two species of the hydrogenosome-containing fungus Neocallimastix that have

30 gue against a vertical origin of trichomonad hydrogenosomes from the proto-mitochondrial endosymbiont

31 These data establish that mitochondria and hydrogenosomes have a common eubacterial ancestor and im

32 n microscopy localized the endosymbiont near hydrogenosomes in the posterior part and near the ectosy

33 a yet contains an alternative organelle, the hydrogenosome, involved in pyruvate metabolism.

34 Hydrogenosomes lack many classical mitochondrial feature

35 lacks mitochondria but has energy-producing hydrogenosomes, makes bacterial-like heat shock proteins

36 These organelles, known as hydrogenosomes, mitosomes, or mitochondrion-like organel

37 mensional analysis of proteins from purified hydrogenosomes obtained from iodinated trichomonads conf

38 n of the mitochondrial carrier family in the hydrogenosome of Trichomonas vaginalis and have shown th

39 trast, it has previously been suggested that hydrogenosomes of the best-studied anaerobic fungus Neoc

40 n with sequence identity to an enzyme of the hydrogenosome organelle that is involved in energy gener

41 ells (VECs) share identity to enzymes of the hydrogenosome organelle, and there was no difference in

42 Multigene families encode enzymes of the hydrogenosome organelles, which have identity to adhesin

43 bic eukaryotes lack mitochondria but contain hydrogenosomes, peculiar organelles of controversial anc

44 The absence of a genome in trichomonad hydrogenosomes precludes such comparisons, leaving the e

45 of MR100, a drug-resistant isolate absent in hydrogenosome proteins and adhesins, were non-adherent.

46 the two organelles differ substantially: in hydrogenosomes, pyruvate oxidation is catalysed by pyruv

47 Binding and translocation of pFd into hydrogenosomes requires the presence of an eight amino a

48 callimastix patriciarum, a model organism in hydrogenosome research.

49 k mitochondria led to the demonstration that hydrogenosomes share a common ancestry with mitochondria

50 of a few proteins indicate that trichomonad hydrogenosomes share a common origin with mitochondria,

51 e for a TvDRP in the fission of T. vaginalis hydrogenosomes, similar to that described for peroxisome

52 double membrane-bound organelle, called the hydrogenosome, that metabolizes pyruvate and produces AT

53 ely, while the 12-kDa FD of the T. vaginalis hydrogenosome was most similar to the 12-kDa FD of gamma

54 address the origin and biological nature of hydrogenosomes, we have established an in vitro protein

55 that symbionts ancestral to mitochondria and hydrogenosomes were present at early stages of eukaryote

56 e function of hydrogen-producing organelles (hydrogenosomes), which occur in anaerobic eukaryotes sca

57 redicts previously unknown functions for the hydrogenosome, which support a common evolutionary origi