ライフサイエンスコーパス: hydrolysis reaction

1 a specific polycolonal antibody followed by hydrolysis reaction.

2 n atom of the scissile phosphate) during the hydrolysis reaction.

3 act as the base that activates water for the hydrolysis reaction.

4 nt not obviously suited to a water-requiring hydrolysis reaction.

5 ATPase and define optimal conditions for the hydrolysis reaction.

6 , and a rate-limiting proton transfer in the hydrolysis reaction.

7 , as compared with approximately 4.5 for the hydrolysis reaction.

8 he hydrolysis of the same acyl-enzyme in the hydrolysis reaction.

9 tially in developing the nucleophile for the hydrolysis reaction.

10 flanking transition states) in the arginine hydrolysis reaction.

11 ing, transition state stabilization, and the hydrolysis reaction.

12 ubstrates on the transition state of the ATP hydrolysis reaction.

13 served motifs are involved in the nucleotide hydrolysis reaction.

14 ail a substantial substituent effect on this hydrolysis reaction.

15 TP and Mg-ATP are the true substrates of the hydrolysis reaction.

16 to stabilize the transition state of the GTP-hydrolysis reaction.

17 constant for the recA protein-catalyzed ATP hydrolysis reaction.

18 e recA protein-catalyzed ssDNA-dependent ATP hydrolysis reaction.

19 rated from the DCI enzyme by a rate-limiting hydrolysis reaction.

20 c effects, while steric effects dominate the hydrolysis reaction.

21 46 does not serve as the general base in the hydrolysis reaction.

22 t include the actual transition state of the hydrolysis reaction.

23 tose through a sequential transfuctosylation-hydrolysis reaction.

24 al or chemical changes of biomass during the hydrolysis reaction.

25 er (Galphai1-R178S) affected exclusively the hydrolysis reaction.

26 meropenem and undergoes a complete catalytic hydrolysis reaction.

27 sition state mimics for the enzyme-catalyzed hydrolysis reaction.

28 ovalent enzyme intermediate to a single-step hydrolysis reaction.

29 y attacking the sn-2 bond, thus favoring the hydrolysis reaction.

30 es both a Claisen condensation and thioester hydrolysis reaction.

31 Y32 to stabilize the transition state of the hydrolysis reaction.

32 hancement of 10(12) over the uncatalyzed P-O hydrolysis reaction.

33 ate-limiting in the NF1(333)-facilitated GTP hydrolysis reaction.

34 complex is rate-limiting in this isopeptide hydrolysis reaction.

35 nsformations, a dehydrogenase reaction and a hydrolysis reaction.

36 also illustrate an intermediate state in the hydrolysis reaction.

37 ctly by the azide clock procedure during the hydrolysis reaction.

38 loyed SPRI measurements of a surface RNase H hydrolysis reaction.

39 e charge develops on the nitrogen during the hydrolysis reaction.

40 irements at the 3'-end of the tRNA for these hydrolysis reactions.

41 ogical samples and in metal-assisted peptide hydrolysis reactions.

42 ant SCPL proteins that extends beyond simple hydrolysis reactions.

43 chanism is operative in GTPase-catalyzed GTP hydrolysis reactions.

44 ctions is different from its specificity for hydrolysis reactions.

45 inder of the products resulted from P-N bond hydrolysis reactions.

46 as lost to either HOH alkylation or P-N bond hydrolysis reactions.

47 ical kinetic properties in the oxidation and hydrolysis reactions.

48 available regarding their thiol addition and hydrolysis reactions.

49 ize fractions during the course of enzymatic hydrolysis reactions.

50 ates of forward, reverse phosphorylation and hydrolysis reactions.

51 ates for Vibrio cholerae sialidase-catalyzed hydrolysis reactions.

52 e number of amidase, transamidase, and ester hydrolysis reactions.

53 tive to the values observed for nonenzymatic hydrolysis reactions.

54 etermination of isotope effects (IEs) on the hydrolysis reactions.

55 ndance of FA, makes the formic acid mediated hydrolysis reaction a potentially important pathway for

56 To characterize the uncatalyzed hydrolysis reaction, a model of peptide release, the tra

57 the mechanism can be deduced by studying the hydrolysis reaction, a simpler system that is amenable t

58 by reading the absorbance of supernatants of hydrolysis reactions after the substrate has been precip

59 However, because of the rapidity of the hydrolysis reaction, an experimental knowledge of the en

60 both for the free energy-yielding nucleotide hydrolysis reaction and for subsequent conformational ch

61 te that is somewhat looser than the alkaline hydrolysis reaction and similar to the PP1-catalyzed mon

62 ential candidate for the general base in the hydrolysis reaction and was shown to interact with the s

63 )- to products, two of which being unique to hydrolysis reactions and taking advantage of the acidic

64 tion state of the reaction from the alkaline hydrolysis reaction, and the transition state is quite d

65 rison to azide ion trapping results from the hydrolysis reactions, and photolysis reaction products (

66 tant (k) and activation energy (Ea) for this hydrolysis reaction are detailed; the results demonstrat

67 iate steps in the actin-myosin catalyzed ATP hydrolysis reaction are energetically coupled through me

68 enyl and methyl phosphates do not, and their hydrolysis reactions are actually slowed by these condit

69 The products of the two consecutive hydrolysis reactions are both GDP and GMP.

70 the reduced enthalpies of activation in both hydrolysis reactions arise not from a destabilization of

71 iridinium ions among alkylation and P-N bond hydrolysis reactions as a function of the concentration

72 Rate enhancements relative to the background hydrolysis reaction at 1 mM catalyst concentration are 6

73 tion states for phosphorothioate and sulfate hydrolysis reactions at the AP active site and, thus, ne

74 g free energy difference simulations for the hydrolysis reaction ATP+H(2)O --> ADP+P(i) in the beta(T

75 The oxidation/hydrolysis reaction attributed to the ferroxidase site h

76 ys can replace the function of Arg418 in the hydrolysis reaction but does not stabilize the closed co

77 -)) under cellular conditions that favor the hydrolysis reaction by a factor of 2 x 10(5).

78 used in nonwater urinals to inhibit the urea hydrolysis reaction by lowering the pH, thereby making t

79 We also found a novel cardiolipin hydrolysis reaction by phospholipase A2 to form diacylat

80 how time-lapse monitoring of an in vitro ATP hydrolysis reaction by the motor domain of a human Kines

81 erature range, any temperature effect on the hydrolysis reaction can be attributed to the effect of t

82 We also show that the complementary hydrolysis reaction can be employed to quench the reacte

83 ep reaction pathway is possible for an ester hydrolysis reaction catalyzed by a serine esterase and,

84 151 is intrinsically involved in the peptide hydrolysis reaction catalyzed by AAP and can be assigned

85 a for AAP, a new catalytic mechanism for the hydrolysis reaction catalyzed by AAP is proposed.

86 In particular, the phosphate monoester hydrolysis reaction catalyzed by Escherichia coli alkali

87 Pre-steady-state kinetic analysis of the ATP hydrolysis reaction catalyzed by the 44/62 protein loadi

88 as the general acid/base during the peptide hydrolysis reaction catalyzed by the co-catalytic metall

89 cylation reaction pathway for numerous ester hydrolysis reactions catalyzed by a serine esterase.

90 for AP, the calculations suggest that their hydrolysis reactions catalyzed by AP and NPP feature sim

91 119 acts as an acid/base during the cleavage/hydrolysis reactions catalyzed by bovine pancreatic ribo

92 phosphate, the nonbridge 18O effect for the hydrolysis reactions catalyzed by Co(III) 1,5,9-triazacy

93 sis, hydroxylaminolysis, glycerololysis, and hydrolysis reactions catalyzed by the mutant enzyme H265

94 the pre-catalytic state associated with the hydrolysis reaction central to the function of RAS and o

95 oteins bound to DNA have the same sequential hydrolysis reaction cycle as the wild type enzyme.

96 on and substrate affinity throughout the ATP hydrolysis reaction cycle.

97 Kinetic analysis of the hydrolysis reaction demonstrates the presence of separat

98 inct manifestations of the dTn-dependent NTP hydrolysis reaction, depending on the length of the dTn

99 The ATP hydrolysis reaction exhibits positive cooperativity with

100 e-substrate complex and intermediates in the hydrolysis reactions have been reported.

101 Furthermore, the ATP hydrolysis reaction in beta(TP) is found to be endotherm

102 n catalysis, modulate the free energy of the hydrolysis reaction in the beta(TP) and beta(DP) sites,

103 Here, we monitored the hydrolysis reaction in the nucleotide-binding domain of

104 dducts 4 at the expense of quinols 3, during hydrolysis reactions in the dark.

105 The enthalpies of activation for the hydrolysis reactions in the two solvents permitted the c

106 perty upon chemical transformation - often a hydrolysis reaction - in the polymer side chain or backb

107 tails of the kinetics of ssDNA-dependent ATP hydrolysis reactions indicate that UvsX-ssDNA presynapti

108 Kinetic analysis of the ATP hydrolysis reaction indicated that the differential stim

109 set of enzymes that catalyzes predominantly hydrolysis reactions involving sugars, nucleic acids, am

110 ing approach, where the competition with the hydrolysis reaction is considered with two variables, a

111 The hydrolysis reaction is greater at neutral pH, whereas th

112 We have found that the pH dependence of the hydrolysis reaction is log-linear, with a gradient of 0.

113 The pH dependence of the NS3 hydrolysis reaction is not affected by the presence of N

114 However, the role of the ATP hydrolysis reaction is not understood.

115 This hydrolysis reaction is performed outside the cytoplasm i

116 The hydrolysis reaction is pH-dependent (optimum pH = 9.5) a

117 This hydrolysis reaction is strictly an interfacial process g

118 n transesterification, although normally the hydrolysis reaction is substantially disfavored relative

119 e site suggests that the nucleophile for the hydrolysis reaction is the metal-bound hydroxide.

120 The hydrolysis reaction is unaffected by substituents on the

121 base chemistry in either the condensation or hydrolysis reactions is nearly completely devoid of acti

122 bilize the tetrahedral intermediate in ester hydrolysis reactions, is utilized here to host and contr

123 sembly regulation, we need to understand GTP hydrolysis reaction kinetics and the GTP cap size.

124 Iterative macrocyclization and hydrolysis reactions lead to 68% of walkers taking two s

125 reaction is reversible even though all three hydrolysis reactions may share the same gem-diol interme

126 ogous amine (5) without tert-butyl groups, a hydrolysis reaction occurred with PhPCl(2).

127 In steady-state turnover, the MgATP hydrolysis reaction occurs at site 1.

128 we show that the group II intron first-step hydrolysis reaction occurs in vivo in place of transeste

129 analysis in DMSO/water mixtures for (i) the hydrolysis reaction of diethyl 2,4-dinitrophenylphosphat

130 where k(non) is the rate of the spontaneous hydrolysis reaction of hUh at 25 degrees C].

131 e phosphatases and from those of the aqueous hydrolysis reaction of pNPP.

132 Phospholipases A2 (PLA2) catalyze the hydrolysis reaction of sn-2 fatty acids of membrane phos

133 agnitude faster than a similar site-specific hydrolysis reaction of the circular form of the Tetrahym

134 rase reaction and dramatically inhibited the hydrolysis reaction of the H412Q enzyme.

135 out the transition states of metal-catalyzed hydrolysis reactions of model phosphate compounds has be

136 ow, for the first time, their application to hydrolysis reactions of nucleotides and nucleic acids.

137 due can function as the general acid/base in hydrolysis reactions of peptides and, through analogy of

138 In the comparative hydrolysis reactions of phosphorothioate and phosphate e

139 The transpeptidation and hydrolysis reactions of sortase have been proposed to pr

140 Hydrolysis reactions of the basic units of biological po

141 thalpies and entropies of activation for the hydrolysis reactions of the monoesters, p-nitrophenyl ph

142 similar to one another than the uncomplexed hydrolysis reactions of the two substrates.

143 similar to one another than the nonenzymatic hydrolysis reactions of the two substrates.

144 ouples sorting signal recognition to the GTP hydrolysis reaction on ARF1.

145 from 1 to 4 min, ~1400 times faster than the hydrolysis reaction outside the thyroxine binding site.

146 e recA protein-catalyzed ssDNA-dependent ATP hydrolysis reaction pathway.

147 e recA protein-catalyzed ssDNA-dependent ATP hydrolysis reaction pathway.

148 er specific to pesticides, to evaluate which hydrolysis reaction pathways are most likely to be relev

149 g result given the availability of competing hydrolysis reaction pathways.

150 ting to metal oxide particles catalyzing the hydrolysis reaction prior to SCR.

151 hat the GAP(334) or NF1(333)-facilitated GTP hydrolysis reaction proceeds through a loose transition

152 brium isotope exchange, we show that the ATP hydrolysis reaction proceeds via an enzyme-phosphate com

153 This reaction, while formally a hydrolysis reaction, proceeds by an oxidative mechanism

154 Thin layer chromatography analysis of the hydrolysis reaction products revealed that ATP was rapid

155 ng kinetic parameters is the surface RNase H hydrolysis reaction rate constant (k(cat)), which was fo

156 to epoxide during the course of the epoxide hydrolysis reaction, resulting in quantitative formation

157 The hydrolysis reaction schemes in the library encode the pr

158 ATX in an uncompetitive manner and slows the hydrolysis reaction, suggesting that ATX inhibition play

159 When both ester groups are aryl groups the hydrolysis reaction (sulfuryl transfer to water) occurs

160 Similar hydrolysis reactions take place with 1 and 2 but much mo

161 The purified protein catalyzes a slow ATP hydrolysis reaction that is essential for its role in mi

162 osphate monoester and aryl methylphosphonate hydrolysis reactions that are much more similar to one a

163 comproportionation, disproportionation, and hydrolysis reactions that control its stability in water

164 Heat treatment also causes hydrolysis reactions that lead to a reduction in 1-monog

165 rectly to the catalysis of the peptidyl-tRNA hydrolysis reaction through stabilization of the leaving

166 harnesses the full chemical potential of the hydrolysis reaction to the synthesis of APS.

167 ial to utilize IAA conjugation and conjugate hydrolysis reactions to achieve more precise spatial and

168 Thus, a tripartite complex controls the GTP hydrolysis reaction triggering disassembly of COPI vesic

169 poxide ring opening in the first step of the hydrolysis reaction; Tyr(465) is highly conserved among

170 ers of magnitude) of the hydrolysis rate for hydrolysis reactions undertaken at pH 11, 12, and 13.

171 released by multiple single nucleotide step hydrolysis reactions until about four base pairs are unw

172 ynamic activation parameters for the peptide hydrolysis reaction, using extensive computer simulation

173 netic isotope effects was determined for the hydrolysis reaction, using NAD+ labeled with 3H, 14C, an

174 cific phosphomonoesterase that catalyzes the hydrolysis reaction via a phosphoseryl intermediate to p

175 sotope effect for sialyl-lactose in the acid hydrolysis reaction was 1.113 +/- 0.012.

176 The transition state for the hydrolysis reaction was modeled computationally using th

177 ase activation protein (GAP)-facilitated GTP hydrolysis reactions, we measured the (18)O KIEs in GTP

178 s, either by photo-induced redox reaction or hydrolysis reaction, which are responsible for the forma

179 P are fully deprotonated at the start of the hydrolysis reaction, which has colored the interpretatio

180 ed by direct association of each step in the hydrolysis reaction with a corresponding step in polymer

181 the acetic acid that is produced during the hydrolysis reaction with a pH indicator.

182 etic isotope effects (KIEs) for AP-catalyzed hydrolysis reactions with several phosphate monoester su

183 of each step to two or more consecutive ATP hydrolysis reactions with similar rates, or the coupling