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1 nd, which can be oxidized in situ with O2 or hydrolyzed.
2 ter which the resulting ester bond is likely hydrolyzed.
3 of benzoate while the POC group was rapidly hydrolyzed.
4 roplets that coalesced during digestion were hydrolyzed 1.4 times slower than individually trapped dr
5 ges the production of 15-epi LXA4 by rapidly hydrolyzing 14,15-EET into its cognate diol, eliminating
7 ir role, TDP2 safeguards genome integrity by hydrolyzing 5'-tyrosyl DNA adducts formed by abortive to
9 verexpress MutT, a nucleotide sanitizer that hydrolyzes 8-oxo-dGTP to the monophosphate, or that lack
10 s also indicated that iPLA2gamma selectively hydrolyzes 9-hydroxy-octadecenoic acid in comparison to
12 a native lactonase capable of promiscuously hydrolyzing a broad range of substrates, including organ
14 strated that concentration of DE-117 and its hydrolyzed active form (hDE-117) was maintained in the a
16 d messenger typically derived from the lipid-hydrolyzing activity of PLDalpha1, is a molecular target
19 d that the CHIKV nsP3 macrodomain is able to hydrolyze ADP-ribose groups from mono(ADP-ribosyl)ated p
20 ome proteins from the macrodomain family can hydrolyze ADP-ribosylated substrates and therefore rever
21 concentrated effluent was then enzymatically hydrolyzed, aiming at obtaining peptides with antioxidan
23 Ls) selectively, while chlorogenate esterase hydrolyzed all chlorogenic acids (CQAs, FQAs) and their
24 sequential hydrolysis by pepsin and trypsin hydrolyzed all heavy molecular weight chains of collagen
28 ptide mimetics and show that 18B7 is able to hydrolyze an oligosaccharide substrate, providing the fi
29 e fermentation, but the extent to which they hydrolyze and consume milk proteins remains poorly under
30 ally formed 5-alkenyl iminohydantoins may be hydrolyzed and oxidatively deprotected to yield hydantoi
31 ining trypsin, the peptide bonds of BSA were hydrolyzed and peptide fragments were desorbed from the
34 lutamate molecules released per ATP molecule hydrolyzed, and high-probability release site terminals
38 mitochondrial form of arginase (ARG2), which hydrolyzes arginine into ornithine and urea, is induced
39 ively charged 1,3-dimethylcytosinium ion was hydrolyzed at a rate similar to the rate of acid-catalyz
40 ng results show that FA residues of TAG were hydrolyzed at specific rates, inducing different bioacce
41 g high levels of basal ATPase activity: they hydrolyze ATP also in the absence of their substrate.
44 and one or two AAA+ HslU ring hexamers that hydrolyze ATP to power the unfolding of protein substrat
47 d for it to recognize forked DNA structures, hydrolyze ATP, catalyze fork remodeling, and act as a st
48 n strictly monomeric Spa47 that is unable to hydrolyze ATP, despite maintaining the canonical ATPase
49 e-scavenging ectonucleotidases CD39 and CD73 hydrolyze ATP, ultimately, to the anti-inflammatory medi
54 ases family, transports two calcium ions per hydrolyzed ATP molecule via an "alternating-access" mech
56 Under pathological conditions, ATP synthase hydrolyzes ATP to replenish protons from the matrix into
57 ins: a nucleotide-binding domain (NBD), that hydrolyzes ATP, and a substrate-binding domain (SBD), wh
61 and encloses ptDNA within, while binding and hydrolyzing ATP to topologically link the clamp and ptDN
62 (Ldb)-infecting bacteriophages, was shown to hydrolyze, besides the simple glycerophosphodiester, two
68 ample accelerates subsequent analysis of the hydrolyzed biomass and increases the coverage of isotopo
70 e-hydrolyzing lactonase SsoPox are unable to hydrolyze bulkyorganophosphates with challenging leaving
72 y fragile substrates such as lactone will be hydrolyzed by a stronger base but will not be activated
75 the large polysaccharide lichenan also being hydrolyzed by GlyA1 The determination of the crystal str
76 lipoproteins are taken up, their CE core is hydrolyzed by liposomal lipases to generate free cholest
78 lagen was extracted from raw bovine hide and hydrolyzed by one of three enzymes - Alcalase, Flavourzy
80 phalosporins, including cefepime, are poorly hydrolyzed by specific ESBL enzymes, and certain strains
81 f extracellular adenosine from ATP, which is hydrolyzed by the CD39/CD73 enzyme pair, attenuates the
82 er connected through the lactam ring that is hydrolyzed by the enzyme BlaC (beta-lactamase) that is n
83 clic walker-track conjugates are efficiently hydrolyzed by the enzyme, leading to high processivity o
87 cond step, the trisaccharide is specifically hydrolyzed by trehalase, to obtain blastose in 43.2% mol
98 inant oligomers or fibrils also showed lower hydrolyzing capacity in the same assays, implicating tau
99 sglycosylases (TGs), i.e., from enzymes that hydrolyze carbohydrates to enzymes that synthesize them,
100 are related to the family of ATP-binding and hydrolyzing carboxylate-amine ligases of the glutamine s
102 est whether administration of an extensively hydrolyzed casein formula (EHCF) containing the probioti
104 lin cofactors and Arl2 as a multisubunit GTP-hydrolyzing catalytic chaperone that cycles to promote a
106 lucidate the role of mPDE phosphorylation in hydrolyzing cellular cAMP, we utilized a phosphodiestera
107 higher levels of both fermentable sugars and hydrolyzed cellulose and altered cell wall properties su
108 a key enzyme in sphingolipid metabolism that hydrolyzes ceramide into sphingosine, is highly expresse
111 mination of kcat/Km showed that the reUmChlE hydrolyzed chlorogenic acid 18-fold more efficiently tha
113 Ddl1 (DDHD domain-containing lipase 1) that hydrolyzes CL, phosphatidylethanolamine, and phosphatidy
117 re design of organophosphate hydrolases that hydrolyze compounds with challenging leaving groups.
118 d to undergo cyclization and was exclusively hydrolyzed, confirming the TE domain as a key catalytic
120 is very different from the one observed for hydrolyzed coumarins, which occlude the entrance of the
123 usekeeping" enzymes that are responsible for hydrolyzing damaged nucleotides in cells and thus preven
127 Prototype MacroD-type macrodomains also hydrolyze derivative linkages on the distal ribose ring.
129 strong evidence that a DDE/D active site can hydrolyze DNA strands of opposite polarity, a mechanism
131 partially hydrolyzed (PH), four extensively hydrolyzed (EH), and one amino acid formula, using bioch
133 st (ACEA) or inhibitors of postsynaptic 2-AG hydrolyzing enzyme ABHD6 (intracellular WWL70) and monoa
134 ic index probably by inhibiting carbohydrate hydrolyzing enzyme activity which could be attributed to
135 nd specialist herbivores regulate their FACs-hydrolyzing enzyme L-ACY-1 to balance FACs' beneficial v
136 cellular pool through inhibition of the cGMP-hydrolyzing enzyme phosphodiesterase type 5 (PDE5) might
137 lied viral gene transfer of the acyl-ghrelin hydrolyzing enzyme, butyrylcholinesterase (BChE), in a m
138 protein signaling (RGS1) protein and a lipid-hydrolyzing enzyme, phospholipase Dalpha1 (PLDalpha1), b
139 dent on the induction of paraoxonase-2, a QS hydrolyzing enzyme, that mitigates the effects of QS mol
142 competitors and broadly implicates NAD(P)(+)-hydrolyzing enzymes as substrates of interbacterial conf
144 ype 4 phosphodiesterases (PDE4) are key cAMP-hydrolyzing enzymes, and PDE4 inhibitors are considered
146 Exhausted CD39(+)CD8(+) T cells from mice hydrolyzed extracellular ATP, confirming that CD39 is en
150 e, polyesters containing 1,2-ethanediol were hydrolyzed faster than polyesters containing 1,8-octaned
153 g transfer RNA (tRNA) editing protein, which hydrolyzes fluorothreonyl-tRNA 670-fold more efficiently
155 idence that weaning to a diet of extensively hydrolyzed formula compared with cow's milk-based formul
156 n to study whether weaning to an extensively hydrolyzed formula reduced the risk of celiac disease au
157 children, early intervention using different hydrolyzed formulas has variable preventative effects on
161 ossibly on amylopectin chains that have been hydrolyzed from the amylopectin molecules during esterif
163 an known EGCases and was able to efficiently hydrolyze gangliosides, globosides, (n)Lc-type GSLs, and
165 cerebrosidase (GBA), a lysosomal enzyme that hydrolyzes glucosylceramide to ceramide and glucose.
167 hodiesterases (GDPDs; EC 3.1.4.46) typically hydrolyze glycerophosphodiesters to sn-glycerol 3-phosph
169 T purified as a nucleotide-free monomer that hydrolyzes GTP and readily binds its analog guanosine 5'
171 drying using polydextrose (5%) and partially hydrolyzed guar gum (5%), was evaluated under accelerate
172 eze-drying, using gum arabic (GA), partially hydrolyzed guar gum (PHGG), and polydextrose (PD) as enc
174 In sharp contrast, oxidized CLs were readily hydrolyzed in mitochondria from wild-type mice during ox
178 g molar mass and structure (cross-linked vs. hydrolyzed) in the structure formation of rye bread was
179 a-glucosidase in A. thaliana root ER bodies, hydrolyzes indole glucosinolates (IGs) in addition to th
180 des the mitochondrial pyrophosphatase, which hydrolyzes inorganic pyrophosphate into two phosphates.
181 the reaction, these intermediates are easily hydrolyzed into imides and amides through vanadium catal
182 galactosylated by BoGal36A, and subsequently hydrolyzed into mainly mannobiose by the beta-mannanase
183 present in the target solution specifically hydrolyzed its cleavage sequence, a consequent decrease
186 paraoxonase 1 (PON1) and the organophosphate-hydrolyzing lactonase SsoPox are unable to hydrolyze bul
187 gradually during the simulated digestions to hydrolyze lactose in milk more efficiently than free lac
188 verned by a standalone peptidase PepN, which hydrolyzes LBS in a pH-sensitive way with most appropria
189 yme may provide a bacterial strategy to both hydrolyze lignocellulose and repel eventual food competi
191 e bacterially expressed recombinant AtABHD11 hydrolyzed lyso(phospho)lipid and monoacylglycerol.
193 uana as well as evaluation of its ability to hydrolyze milk casein to generate antimicrobial peptides
195 on systems collaborate to detect, repair, or hydrolyze mutant, damaged, and mislocalized proteins.
199 sphingomyelin and, surprisingly, can instead hydrolyze nucleoside diphosphates and triphosphates, whi
200 iesterase (NPP) family, the members of which hydrolyze nucleoside phosphates, phospholipids, and othe
202 The Na(+),K(+)-ATPase (NKA or Na/K pump) hydrolyzes one ATP to exchange three intracellular Na+ (
204 hingobium sp. strain TCM1 that is capable of hydrolyzing organophosphate flame retardants was determi
205 The protein exerts its scavenging action by hydrolyzing oxidized nucleotides, thus avoiding their mi
211 ural antibodies were "catalytic" and able to hydrolyze peptide or phosphodiester bonds in antigens.
212 ant peptide-receptive MHC molecules with non-hydrolyzed peptide-loaded MHC complexes by monitoring th
213 s are genuine Xaa-Pro aminopeptidases, which hydrolyze peptides with proline at the second position (
214 13)C labeled amino sugars and amino acids by hydrolyzing peptidoglycan isolated from isotopically lab
215 ably, residue His-207 alone is sufficient to hydrolyze PGP, indicating a specific catalytic mechanism
216 M formulas, one nonhydrolyzed, two partially hydrolyzed (PH), four extensively hydrolyzed (EH), and o
218 , activate phospholipase C (PLC) isozymes to hydrolyze phosphatidylinositol 4,5-bisphosphate into the
219 es, phospholipase C-beta (PLC-beta) isoforms hydrolyze phosphatidylinositol 4,5-bisphosphate to the s
222 he rapamycin-recruitable phosphatase Sac1 to hydrolyze PI(4)P and the P4M probe to visualize PI(4)P s
224 PLIP1 is a phospholipase A1 In vivo, PLIP1 hydrolyzes polyunsaturated acyl groups from a unique chl
225 ric dispersions (HVPD) composed by partially hydrolyzed polyvinyl acetate (PVA), borax, and water, we
226 e rather than endomembranes, and rather than hydrolyzing PPi to create pmf, pmf is utilized to synthe
227 uble protease ADAMDEC1, recombinant ADAMDEC1 hydrolyzed pro-EGF1020-1027, and this activity was inhib
228 activated platelets release ADAMDEC1, which hydrolyzes pro-EGF to soluble HMW-EGF, that HMW-EGF is a
229 ed acid p-TSA.H2O, the reaction afforded the hydrolyzed product propargylated-1,3-dicarbonyl compound
230 The newly identified tomato phytaspases hydrolyzed prosystemin at two aspartate residues flankin
231 source of protein, used for present study to hydrolyze protein, peptide separation and its functional
232 vestigating the effectiveness of a partially hydrolyzed protein formula supplemented with nondigestib
233 lites, and pH of infants receiving partially hydrolyzed protein formula supplemented with nondigestib
238 H(+)-PPases have a well-documented role in hydrolyzing pyrophosphate (PPi) and capturing the releas
239 n this report, we demonstrate its ability to hydrolyze R-loops in Escherichia coli exposed to UV stre
240 intains the PDE8-RIalpha complex while being hydrolyzed, revealing an undiscovered mode for amplifica
241 this hypothesis, we focused on enzymes that hydrolyze rhamnosidic bonds, as cleavage of these linkag
243 accompanied by induction of the enzyme that hydrolyzes S-adenosylhomocysteine (SAH), a product and i
246 , we demonstrated that this protease rapidly hydrolyzes Staphylococcus aureus protein A, an important
248 is a highly glycosylated dimeric enzyme that hydrolyzes sucrose and releases fructose from various fr
249 ng platelet surface proteins showed ADAMDEC1 hydrolyzed surface pro-EGF to HMW-EGF that stimulated He
250 r facilitates the subsequent condensation of hydrolyzed TEOS, which builds up the shell layer of smHS
251 Then, the EXO III amplification was used to hydrolyze the 3'-end of the dsDNA after the recognition
252 side hydrolases (GH) are enzymes that mainly hydrolyze the glycosidic bond between two carbohydrates
253 T5) and Cholera toxin subunit A (CTA), which hydrolyze the nicotinamide and transfer (tz)ADP-ribose t
255 fungal (FP400 and FPII) sources were used to hydrolyze the red blood cell fractions (RBCFs) separated
257 the potential of anaerobic biogas sludge to hydrolyze the synthetic compostable polyester PBAT (poly
258 ved attention on the basis of its ability to hydrolyze the thiopurine effector metabolites 6-thio-deo
259 was prevented, or when purified proteasomes hydrolyzed the associated ubiquitin conjugates, Usp14 an
261 N-acyl homoserine lactonase, an enzyme that hydrolyzes the ester bond of the homoserine lactone of N
263 clusters harbor an enzyme that specifically hydrolyzes the isopeptide bond to yield the linear pepti
264 essed in bone, teeth, liver, and kidney that hydrolyzes the mineralization inhibitor inorganic pyroph
265 he organophosphate degradation (opd) island, hydrolyzes the triester bond found in a variety of organ
266 ure present with heterogeneous levels of IgG hydrolyzing the generic proline-phenylalanine-arginine-m
269 crystallographic structures we show that to hydrolyze their substrates, three structurally related m
270 hiamin diphosphate (ThDP), plants must first hydrolyze thiamin monophosphate (ThMP) to thiamin, but d
272 o produce phosphocholine, which PHOSPHO1 can hydrolyze to liberate Pi This hypothesis is supported by
273 e of T4 PNK, the 3'-phosphoryl of HP-MBs was hydrolyzed to 3'-hydroxyl, thus serving as primers to in
274 and release of (15) NH3 suggest that urea is hydrolyzed to ammonia intracellularly, then a portion is
276 ive an oxazolidinone, which could be readily hydrolyzed to an oxazolidin-2-one or an amino alcohol.
277 potted catshark (Scyliorhinus canicula) were hydrolyzed to degrees of hydrolysis (DH) of 3-4-5-6% wit
278 icantly increase brain DHA, because they are hydrolyzed to free DHA and are absorbed as triacylglycer
279 fide (COS) upon activation, which is quickly hydrolyzed to H2 S by the ubiquitous enzyme carbonic anh
282 The double C-O coupling products may be hydrolyzed to vicinal tricarbonyl compounds, which are o
283 ther to form a succinimide intermediate that hydrolyzes to produce the corresponding isoaspartyl pept
284 a Zn(2+)-dependent metalloisopeptidase that hydrolyzes ubiquitin from tagged proteins that are traff
285 associated with tau and were less active in hydrolyzing ubiquitinated proteins, small peptides and A
286 e compounds, mainly starch and proteins, are hydrolyzed upon germination to allow seedling growth.
287 and the prevalence of the urease enzyme that hydrolyzes urea, minerals readily precipitate in nonwate
288 s and reactor performance in synthetic fully hydrolyzed urine as the pH decreased over time in respon
291 a generalized bioscavenger by binding and/or hydrolyzing various xenobiotic agents and toxicants, man
294 , whole crickets (Gryllodes sigillatus) were hydrolyzed with alcalase at 0.5, 1.5, and 3.0% (w/w) for
297 khorasan wheat, emmer, lupine and pea) were hydrolyzed with commercial enzymes and Lactobacillus spp
298 The native and denatured RBP fractions were hydrolyzed with papain and trypsin for 3h at optimum con
300 This explains why CtXyl5A is capable of hydrolyzing xylans that are extensively decorated and th
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