ライフサイエンスコーパス: hydroperoxide

1 anganese in the presence of TBHP (tert-butyl hydroperoxide).

2 dation products (conjugated dienes and lipid hydroperoxides).

3 ies suggested to be either a superoxide or a hydroperoxide.

4 from oxidative stress induced by tert-butyl hydroperoxide.

5 ificantly increased resistance to tert-butyl hydroperoxide.

6 its corresponding alkylperoxy species, ethyl hydroperoxide.

7 resence of the organic hydroperoxide t-butyl hydroperoxide.

8 ed cyclization cascade of a chiral bis(epoxy)hydroperoxide.

9 hydroperoxide lyase (HPL) action on linoleyl hydroperoxides.

10 1 failed to give metabolites with any of the hydroperoxides.

11 xidases were equally sensitive to fatty acid hydroperoxides.

12 e peroxides, peroxynitrite, and phospholipid hydroperoxides.

13 olecule scavengers of amino acid and protein hydroperoxides.

14 inhibiting the formation of TBARS and lipid hydroperoxides.

15 the reduction of hydrogen peroxide and lipid hydroperoxides.

16 for synthesis of primary and secondary alkyl hydroperoxides.

17 f Ohr in bacterial responses toward distinct hydroperoxides.

18 alyzes the reduction of H(2)O(2) and organic hydroperoxides.

19 ility of OhrR to sense intracellular organic hydroperoxides.

20 t of Pseudomonas aeruginosa toward different hydroperoxides.

21 enocysteine, leading to accumulation of PUFA hydroperoxides.

22 hydroxides was clearly favoured over that of hydroperoxides.

23 which oxidize polyunsaturated fatty acids to hydroperoxides.

24 alize olefins to afford a new class of alkyl hydroperoxides.

25 (Gpx4) is a major scavenger of phospholipid hydroperoxides.

26 h included omega-6 and omega-3 derived lipid hydroperoxides, 2,4-alkadienals, 2-alkenals, 4,5-epoxy-2

27 ow involves oxidation of complex 2 by Pt(IV) hydroperoxide 4.

28 duced from oxidation of isoprene 4-hydroxy-3-hydroperoxide (4,3-ISOPOOH) under low-NO conditions, wer

29 cholesterol (chol) autoxidation gives chol 7-hydroperoxide (7-OOH) as the sole primary product is sho

30 tom substituted cyclic alkenes by tert-butyl hydroperoxide (70% TBHP in water) using catalytic dirhod

31 the ChOOH 3beta-hydroxycholest-5-ene-7alpha-hydroperoxide (7alpha-OOH) in liposomes, stimulated cell

32 d, octanoic acid, nonanoic acid), along with hydroperoxides (9- and 13-hydroperoxy-octadecadienoylgly

33 Cells treated with tert-butyl hydroperoxide, a known ROS stimulus, were also evaluated

34 The total hydroperoxides accumulated along the 10 days of fermenta

35 e almost comparable to derivatives of flavin hydroperoxide acting as oxidizing agents in monooxygenas

36 -dicyano-p-benzoquinone) or TBHP (tert-butyl hydroperoxide), along with FeCl24 H2O (10 mol %).

37 nes against oxidative toxicity of tert-butyl hydroperoxide and 4-hydroxynonenal, against free radical

38 rmination of the differing relative rates of hydroperoxide and acid formation with changes in hydroca

39 hemistry, generated by the presence of cumyl hydroperoxide and Cu(2+) in solution, when supplemented

40 mation were identified, the iminium ion, the hydroperoxide and dimer of THIQ, and a new ring opened i

41 We replaced hydrogen peroxide with t-butyl hydroperoxide and found that, although the palladium eno

42 as highly sensitive to killing by tert-butyl hydroperoxide and H2O2 compared to the sensitivity of th

43 potentiated the cytotoxic effects of t-butyl hydroperoxide and hydrogen peroxide on mouse DA MN9D cel

44 Prx1 to hyperoxidation caused by both urate hydroperoxide and hydrogen peroxide.

45 amino acids after incubation with tert-butyl hydroperoxide and hypochlorous acid in vitro, we identif

46 duction and evolution reactions, and lithium hydroperoxide and lithium hydroxide are identified as pr

47 and methylene produced negative effects, and hydroperoxide and nitrate groups produced the smallest a

48 The lipid hydroperoxide and p-Anisidine values of emulsions genera

49 Emulsified oils had lower detectable lipid hydroperoxide and p-Anisidine values than their correspo

50 d derivative failed to react with tert-butyl hydroperoxide and potassium hydroxide, demonstrating tha

51 Furthermore, fatty acid hydroperoxide and SIN-1 both induced Ohr expression in t

52 amethylcyclam) by treatment with tert -butyl hydroperoxide and strong base in acetonitrile to generat

53 Based on hydroperoxide and TBARS analysis, sinapic acid and rutin

54 process of membrane lipids, MDA, fatty acid hydroperoxides and 7-ketocholesterol.

55 nd old WT liver, including lipofuscin, lipid hydroperoxides and acrolein, as well as increased hepato

56 markers of oxidative stress including lipid hydroperoxides and alkenals were significantly higher in

57 eactions of a series of gold(III) peroxides, hydroperoxides and alkylperoxides.

58 as demonstrated by the automated analysis of hydroperoxides and carboxylic acids (by microplate reade

59 Hydroperoxides and carboxylic acids are key primary prod

60 Induction period of the formation of hydroperoxides and conjugated dienes at 50 degrees C and

61 r production of some lipid mediators such as hydroperoxides and EPA-derived prostaglandins, such as 1

62 h the interaction of carbonyl compounds with hydroperoxides and H2O2 in acidic media, as such reactio

63 E/ml emulsion delayed the formation of lipid hydroperoxides and headspace hexanal in the 5.0%(wt) cor

64 re much stronger oxidizing agents than alkyl hydroperoxides and in some cases are almost comparable t

65 -ohrR) displayed limited or no resistance to hydroperoxides and INH.

66 oups, which showed decreased levels of lipid hydroperoxides and MDA.

67 role in modulating the levels of fatty acid hydroperoxides and peroxynitrite, both of which are invo

68 ulated duodenal digests of the porridges had hydroperoxides and therefore caused LDL oxidation.

69 Lipid hydroperoxides and thiobarbituric acid reactive substanc

70 eroxides (tyrosyl, tryptophan, and histidine hydroperoxides) and CBA, and these values (7-23 M(-1) s(

71 mation of (1) an ozonide intermediate, (2) a hydroperoxide, and (3) cis,cis-muconic acid.

72 oxify ROS such as hydrogen peroxide, organic hydroperoxide, and peroxynitrite.

73 Cyclic peroxides, hydroperoxides, and epoxy alcohols are major products fo

74 t functions in the detoxification of organic hydroperoxides, and expression of ohr is often regulated

75 tus, oxidative stress index, levels of lipid hydroperoxides, and the activities of paraoxonase, aryle

76 ously determine both types of products using hydroperoxide- and acid-sensitive moieties conjugated to

77 e dioxirane intermediate via addition of the hydroperoxide anion to the ketone and revealed that this

78 y the concurrent activation of persulfate by hydroperoxide anion, which is generated by the base cata

79 ation of a carbanion intermediate and that a hydroperoxide (anion) is involved.

80 nols, various allylic alcohols, and an alkyl hydroperoxide are viable coupling partners in this proce

81 Tyrosine-derived hydroperoxides are formed in peptides and proteins expos

82 Amino acid hydroperoxides are unstable intermediates that can furth

83 a secondary rather than tertiary surfactant hydroperoxide, arguing for an orthogonal alkene on water

84 e oxidation catalyst by addition of an alkyl hydroperoxide as a chemical trigger and oxidant.

85 ) oxide as a catalyst and aqueous tert-butyl hydroperoxide as an oxidant.

86 lated Cu-catalyzed reaction using tert-butyl hydroperoxide as oxidant and how to overcome this limita

87 is using Lewis acids as catalyst and organic hydroperoxide as oxidant, covalent binding of the hydrop

88 ast, for olefin epoxidation using tert-butyl-hydroperoxide as oxidant, the open and closed catalysts

89 inoleic acid hydroperoxide, indicating lipid hydroperoxides as the likely physiologic targets.

90 with unprecedented selectivity to give alkyl hydroperoxides as the major products.

91 Cis,trans-conjugated dienes associated with hydroperoxides, as well as monoepoxides, cis,trans-2,4-a

92 Hydroperoxide-based kinetic parameters (IP, induction pe

93 The next step was an autoxidation to hydroperoxides bearing the heteroaromatic oxazoles.

94 per at pH 7.4 and 4 degrees C, i.e., rich in hydroperoxides but low in oxysterols.

95 hat Ohr contributes to resistance to organic hydroperoxide, but not hydrogen peroxide, in B. abortus

96 of 18:2n-6 and 18:3n-3 with formation of 13S-hydroperoxides by hydrogen abstraction and oxygenation i

97 This is in contrast to CHA, where the hydroperoxide channel is the dominant oxidation pathway,

98 ated trafficking of redox-active cholesterol hydroperoxides (ChOOHs) can result in site-specific Mito

99 wild-type strain (MSWt) induced with cumene hydroperoxide (CHP) and t-butyl hydroperoxide (t-BHP).

100 hereas organic hydroperoxides such as cumene hydroperoxide (CHP) deactivate AphB and OhrR.

101 oxanes, isoprostanes, resolvins, hydroxides, hydroperoxides, coming from eicosapentaenoic (EPA), arac

102 ned by analysing protein-bound peroxides and hydroperoxide compounds in water-methanol and chloroform

103 obic replacements of Leu(336) can modify the hydroperoxide configurations at C-9 with little effect o

104 Hydroperoxide content of the samples was also measured.

105 as significant in terms of the inhibition of hydroperoxide content, while formation of secondary lipi

106 The hydroperoxides could conveniently be converted to the co

107 l, left ventricle myocardial levels of lipid hydroperoxides, cytochrome-c, and mitochondrial aconitas

108 ine (1a) into a catalytic chain-breaking and hydroperoxide-decomposing antioxidant by replacing the 2

109 ere asthma (r = -0.55; P = 0.03) and t-butyl-hydroperoxide decreased LXA4 and 15-epi-LXA4 biosynthesi

110 er-soluble compounds (e.g., strong acids and hydroperoxides) deposit with low surface resistance wher

111 ane may account for the formation of the bis-hydroperoxide derivative.

112 eroxide addition to tyrosyl radical are para-hydroperoxide derivatives (para relative to the position

113 e restored by treatment of H388YmPGHS-2 with hydroperoxide derivatives of AA or 2-AG.

114 N-terminal tyrosines, bicyclic indolic para-hydroperoxide derivatives were formed ((2S,3aR,7aR)-3a-h

115 e depletion and ROS production by tert-butyl-hydroperoxide did not trigger the unfolded protein respo

116 icated that fatty acid (but not cholesterol) hydroperoxides docked well into the active site of Ohr f

117 nsitive to oxidation and can be converted to hydroperoxides either by superoxide reacting with the Ty

118 of the transition structures responsible for hydroperoxide (ene product) are lower than that for diox

119 Downstream, the LOX products 13-fatty acid hydroperoxides esterified to galactolipids and phospholi

120 ; (ii) substrate radical rebound to a Cu(II) hydroperoxide favors the proximal, nonprotonated oxygen;

121 (GPx4), which specifically metabolizes lipid hydroperoxides, fell in TNFalpha-stimulated cells prior

122 f (i) diastereoselectivities in dioxetane or hydroperoxide formation and (ii) regioselectivity leadin

123 s a new mechanism for amino acid and protein hydroperoxide formation in biological systems.

124 At 37 degrees C, the rate of lipid hydroperoxide formation increased with decreasing drople

125 lamb, pork and chicken to investigate their hydroperoxide formation potential.

126 Hydroperoxide formation was examined at different pH val

127 ations-monitored either by O2 consumption or hydroperoxide formation-are the most reliable way to obt

128 rogeneous reaction of aldehydes with organic hydroperoxides forming peroxyhemiacetals can lead to a l

129 mmetrical perepoxide transition state in the hydroperoxide-forming step.

130 Here we also show formation of tryptophan hydroperoxide from tryptophan exposed to co-generated fl

131 Our results demonstrate that ROS and lipid hydroperoxides function as not-yet-recognized unconventi

132 C induce fragmentation of this beta-hydroxy hydroperoxide generating aldehydes, especially in the pr

133 The antioxidants, catalase, phospholipid hydroperoxide glutathione peroxidase, thioredoxin, and g

134 the following order: hydroxyl >> carboxyl > hydroperoxide > nitrate >> methylene (where nitrate and

135 rapidly and specifically with linoleate 10S-hydroperoxide (>2,500 turnovers/s) with a hydroperoxide

136 mitochondrial superoxide and cellular lipid hydroperoxides, had reduced activities of superoxide dis

137 discovery that varying the structure of the hydroperoxide has a significant impact on the enantiosel

138 fluorometric method for the determination of hydroperoxides (HP) in edible oils and fats using the re

139 Several species of OxCE, such as keto, hydroperoxide, hydroxy, and epoxy cholesteryl ester deri

140 rious kinds of oxidation products comprising hydroperoxides, hydroxy-dienes and other alcohols, epoxi

141 e, Prx1 and Prx2 are likely targets of urate hydroperoxide in cells.

142 stimulated cells took up substantially more hydroperoxide in Mito than controls, with a resulting lo

143 gainst oxidative damage caused by tert-butyl hydroperoxide in the human hepatocellular HepG2 cell lin

144 monium iodide as the catalyst and tert-butyl hydroperoxide in water (T-Hydro) as the oxidant affords

145 This approach was used to detect protein hydroperoxides in cell lysates obtained from macrophages

146 quantification of both carboxylic acids and hydroperoxides in hydrocarbon samples.

147 activity in both models and decreased lipid hydroperoxides in MCD mice.

148 nes by its unique activity to reduce complex hydroperoxides in membrane bilayers and lipoprotein part

149 In contrast, the ability to inactivate lipid hydroperoxides in oxidized low-density lipoprotein was c

150 intact ohrR gene could be induced by organic hydroperoxides in vitro and in the intracellular environ

151 Ohr showed high activity with linoleic acid hydroperoxide, indicating lipid hydroperoxides as the li

152 gen and fumitremorgin A relied not only on a hydroperoxide/indole hemiaminal cyclization, but also on

153 The 20xi-hydroperoxides induced spectral shifts in CYP27A1 and CY

154 mouse liver were resistant to Ca(2+)/t-butyl hydroperoxide-induced mPTP opening in comparison with wi

155 nds protected HepG2 cells against tert-butyl hydroperoxide-induced oxidative cytotoxicity.

156 tes protected HepG2 cells against tert-butyl hydroperoxide-induced oxidative damage to a similar exte

157 glutathionylation correlated with tert-butyl hydroperoxide-induced ROS generation.

158 A surface hydroperoxide intermediate has been detected upon oxidat

159 d to the peroxide ligand to yield a kappa(1)-hydroperoxide intermediate.

160 om a semi-hydroquinone species and a Co(III)-hydroperoxide intermediate.

161 echanism involving decomposition of hydroxyl hydroperoxide intermediates followed by hemiacetal ring

162 ion, reaction of (N4)Pd(II)Me(2) with cumene hydroperoxide involves a heterolytic O-O bond cleavage,

163 Urate hydroperoxide is a product of the oxidation of uric acid

164 peroxide as oxidant, covalent binding of the hydroperoxide is not required, and instead dative coordi

165 a Fenton-like reaction between linoleic acid hydroperoxide (LAHP) tethered on iron oxide nanoparticle

166 te the transient imbalance between the lipid hydroperoxide level and antioxidant status related to a

167 levels of fresh eggs but reduced their lipid hydroperoxide levels compared to controls.

168 is but attenuated protein carbonyl and lipid hydroperoxide levels in 3T3-L1 cells.

169 status, oxidative stress index (OSI), lipid hydroperoxide levels, paraoxonase, arylesterase, and cer

170 d lower plasma troponin and myocardial lipid hydroperoxides levels (vs. controls, both p<0.05, analys

171 ers like TBA value, carbonyl value and lipid hydroperoxides (LHPODs) exhibited significant negative c

172 action between linoleic acid (LH) and its 13-hydroperoxide (LOOH) catalysed by lipoxygenase.

173 lso examined serum lipid peroxidation (lipid hydroperoxides, LPH and 4-hydroxy-2-nonenal, 4-HNE), in

174 er concentration of hexanal, probably due to hydroperoxide lyase (HPL) action on linoleyl hydroperoxi

175 pathway, the allene oxide synthase (AOS) and hydroperoxide lyase (HPL) branches, which are responsibl

176 0S-hydroperoxide (>2,500 turnovers/s) with a hydroperoxide lyase activity specific for the 10S-hydrop

177 ical characteristics, lipoxygenase activity, hydroperoxide lyase activity; linoleic acid and linoleni

178 se and the newly identified catalase-related hydroperoxide lyase and given the role of aldehydes in p

179 e signal, in ceh1 (constitutively expressing hydroperoxide lyase1)-mutant plants leads to large-scale

180 rate, is known only in plant cytochrome P450 hydroperoxide lyases.

181 The total level of hydroperoxides (measured by the triiodide assay) increas

182 arget because it dominates the Trx-dependent hydroperoxide metabolism and the reduction of ribonucleo

183 Oxidation of Prxs by urate hydroperoxide might affect cell function and be partiall

184 The formation of urate hydroperoxide might be a key event in vascular inflammat

185 ly oxidized RO2 radicals containing a single hydroperoxide moiety.

186 and spectroscopic characteristics of lithium hydroperoxide monohydrate are scrutinized both experimen

187 suggest that the oxidation of Prx2 by urate hydroperoxide occurs by a three-step mechanism, where th

188 studies on this reaction suggest that the C2 hydroperoxide of dibenzothiophene sulfone reacts with fl

189 Hydroperoxides of amino acid and amino acid residues (ty

190 activity with restricted specificity toward hydroperoxides of unsaturated fatty acid.

191 Sperm whale myoglobin forms a hydroperoxide on Tyr-151 in a hydrogen peroxide/superoxi

192 in the presence or absence of either t-butyl hydroperoxide or phenylarsine oxide in comparison with w

193 Select samples were exposed to t-butyl-hydroperoxide or sEH inhibitor (sEHI) before activation.

194 Urate hydroperoxide oxidized Prx2 from intact erythrocytes to

195 Urate hydroperoxide oxidizes glutathione and sulfur-containing

196 olic 2-Cys Prx1 and Prx2 revealed that urate hydroperoxide oxidizes these enzymes at rates comparable

197 oes not; an additional MSH-dependent organic hydroperoxide peroxidase exists; and elevated isoniazid

198 homolog of the conserved osmC, which encodes hydroperoxide peroxidase, shown to protect bacteria agai

199 d V materials activate H2O2 to form pools of hydroperoxide, peroxide, and superoxide intermediates.

200 ydrogen peroxide, peroxynitrite, and organic hydroperoxides, peroxiredoxins (Prdxs) represent a major

201 HNO3), hydrogen cyanide (HCN), hydroxymethyl hydroperoxide, peroxyacetic acid, organic hydroxy nitrat

202 e have preliminarily attributed to a ferrous-hydroperoxide precursor that undergoes heterolysis to ge

203 f Lto1 function renders cells susceptible to hydroperoxide pro-oxidants, though this type of sensitiv

204 rols and the subsequent decomposition of the hydroperoxide products to cytotoxic derivatives are disc

205 sed on the formation of polar compounds than hydroperoxides provided more reliable results to evaluat

206 Fatty acid profiles, formation of hydroperoxides (PV), thiobarbituric acid reactive substa

207 These hydroperoxides rearrange to bicyclic derivatives that ar

208 rimarily regulates the expression of organic hydroperoxide reductase (Ohr) in bacteria.

209 scriptional regulator for the enzyme organic hydroperoxide reductase (Ohr).

210 The effector proteins, alkyl hydroperoxide reductase and acetyl-CoA acetyltransferase

211 Alkyl hydroperoxide reductase C (AhpC) is an enzyme responsibl

212 oxidative stress, suggesting that the alkyl hydroperoxide reductase is an important regulator of red

213 Organic hydroperoxide reductase regulator (OhrR) in bacteria is

214 Escherichia coli alkyl hydroperoxide reductase subunit C (AhpC) is a peroxiredo

215 Overexpressing one of these proteins, alkyl hydroperoxide reductase subunit F (a protein defending b

216 , a dedicated peroxiredoxin reductase, alkyl hydroperoxide reductase subunit F (AhpF), catalyzes the

217 Finally, the alkyl hydroperoxide reductase, a primary scavenger of endogeno

218 osomes, the detoxification of broad spectrum hydroperoxides relies on a unique cascade composed of tr

219 I aneuploidy, wherein these proteins support hydroperoxide removal with the reducing equivalents gene

220 Organic hydroperoxide resistance (Ohr) enzymes are unique Cys-ba

221 an ~15-kDa protein determined to be organic hydroperoxide resistance protein (Ohr).

222 The organic hydroperoxide resistance protein Ohr has been identified

223 ilic attack of the urate anion on the flavin hydroperoxide resulting in the formation of 5-hydroxyiso

224 used directly with our previously described hydroperoxide-sensitive coumarin-conjugated phosphine pr

225 roxide-shunt reaction is proposed, where the hydroperoxides serve as both donor for reduced oxygen an

226 A P450 hydroperoxide-shunt reaction is proposed, where the hydr

227 ed in which ferrous iron-superoxo and ferric hydroperoxide species are reaction intermediates, and th

228 Copper(II) hydroperoxide species are significant intermediates in p

229 RNAi silencing of phospholipid hydroperoxide-specific GPx (GPx4) in NIH/3T3 cells led t

230 r (OhrR) in bacteria is a sensor for organic hydroperoxide stress and a transcriptional regulator for

231 e in protecting B. abortus 2308 from organic hydroperoxide stress in in vitro assays, this protein is

232 The organic hydroperoxide stress resistance regulator (OhrR) is a Ma

233 o in vitro but also to intracellular organic hydroperoxide stress.

234 o sense and respond to intracellular organic hydroperoxide stress.

235 bon chain within the conjugated diene of the hydroperoxide substrate, is known only in plant cytochro

236 and repress its expression, whereas organic hydroperoxides such as cumene hydroperoxide (CHP) deacti

237 Cumene hydroperoxide-supported metabolism was measured to deter

238 hrR complexes in the presence of the organic hydroperoxide t-butyl hydroperoxide.

239 e protection as well as decreased tert-butyl hydroperoxide (t-BHP) induced oxidative cytotoxicity in

240 with cumene hydroperoxide (CHP) and t-butyl hydroperoxide (t-BHP).

241 to the oxidative damaging agent, tert-butyl hydroperoxide (TBH), are repaired with fast and slow com

242 ert an antioxidant action against tert-butyl hydroperoxide (TBH)-induced oxidative damage to Caco-2 c

243 salen complex as the catalyst and tert-butyl hydroperoxide (TBHP) as the oxidant, allylic activations

244 tions of N,N-dialkylanilines with tert-butyl hydroperoxide (TBHP) as the oxidant.

245 in dioxane as solvent and aqueous tert-butyl hydroperoxide (TBHP) as the terminal oxidant.

246 s, proteins were pre-treated with tert-butyl hydroperoxide (TBHP), a bulky peroxide, to oxidise only

247 ed significant protection against tert-butyl hydroperoxide (tBHP), a damaging organic peroxide.

248 nd cytoprotective effects against tert-butyl hydroperoxide (TBHP)-induced cytotoxicity of Caco-2 cell

249 ffects of sheep whey protein from tert-butyl hydroperoxide (tBHP)-induced oxidative stress in muscle

250 Oxidative stress was induced by tert-butyl hydroperoxide (tBHP).

251 ied, CuCl(2).2H(2)O/O(2) and CuBr/tert-butyl hydroperoxide (TBHP).

252 Di, respectively) were exposed to tert-butyl hydroperoxide (tBHP).

253 e reactive oxygen species-inducer tert-butyl hydroperoxide (TBHP).

254 oceeds cleanly in the presence of tert-butyl hydroperoxide (TBHP, 2) using low loadings of VO(O(i)Pr)

255 Fucus serratus to protect against tert-butyl hydroperoxide (tert-BOOH) induced stress in Caco-2 cells

256 re sensitive to hydrogen peroxide and cumene hydroperoxide than the parental strain.

257 ROS oxidize phospholipids to hydroperoxides that are friable and fragment adjacent to

258 ysteine in Gpx4 prevents elimination of PUFA hydroperoxides; these findings suggest new strategies fo

259 Hydroperoxide, thiobarbituric acid reactive substances (

260 sting that OhrR senses intracellular organic hydroperoxides through Cys residue.

261 mation of oxygen-containing defects by lipid hydroperoxides through photo-oxidation.

262 n to mediate the reduction of cholesterol 25-hydroperoxide to 25-hydroxycholesterol, a role of potent

263 pidly oxidize while reducing the toxic lipid hydroperoxide to a nonreactive lipid hydroxide, whereas

264 Addition of cholesterol 25-hydroperoxide to the enzymes CYP27A1 and CYP11A1 induced

265 se-related hemoproteins transform fatty acid hydroperoxides to allene oxides, highly reactive epoxide

266 BA) probe reacts with amino acid and protein hydroperoxides to form the corresponding fluorescent pro

267 by the iron-dependent accumulation of lipid hydroperoxides to lethal levels.

268 tated rapid decomposition of preformed lipid hydroperoxides to secondary lipid oxidation products.

269 s of oxygen transfer from these heterocyclic hydroperoxides to thioanisole, obtained by calculations

270 mutant had diminished resistance to organic hydroperoxide toxicity but increased hydrogen peroxide r

271 the following: Ohr protects against organic hydroperoxide toxicity, whereas ergothioneine does not;

272 onstants for the reaction between amino acid hydroperoxides (tyrosyl, tryptophan, and histidine hydro

273 al-time monitoring of amino acid and protein hydroperoxides using the CBA-based assay.

274 Oxidation markers (hydroperoxide value and head space n-hexanal) increased

275 milar in all emulsions as concluded from the hydroperoxide value.

276 ing storage time, a progressive formation of hydroperoxide was found as evidenced by the increase in

277 ing storage time, a progressive formation of hydroperoxide was found as evidenced by the increase in

278 A beta-hydroxy hydroperoxide was obtained through base-catalyzed dispro

279 ted hemoprotein reactivity toward fatty acid hydroperoxides, we detected a novel candidate in the cya

280 For first time total hydroperoxides were determined by FOX-1 assay to follow

281 es which can use as substrate the fatty acid hydroperoxides were differentially regulated in bacteriz

282 Further reactions of hydroperoxides were followed by determining secondary ox

283 and further reactions of intact steryl ester hydroperoxides were followed in a tripalmitin matrix mai

284 n the presence of superoxide, high yields of hydroperoxides were formed by LPO and urate.

285 Phenols and hydroperoxides were identified as being the most sensiti

286 constants between Ohr and several fatty acid hydroperoxides were in the 10(7)-10(8) M(-1)s(-1) range

287 Intact steryl ester hydroperoxides were isolated from the lipid matrix by a

288 cardial lactate) and oxidative stress (lipid hydroperoxides) were measured by enzyme-linked immunosor

289 Primary oxidation products (lipid hydroperoxides) were measured with a ferrous oxidation-x

290 ing multifunctional organosulfates (OSs) and hydroperoxides, were chemically characterized in both la

291 Importantly, tert-butyl hydroperoxide, which is not a StAR protein ligand, was e

292 kenes to form endoperoxides, diooxetanes, or hydroperoxides, which are not observed in our system.

293 Fatty acid hydroperoxides, which are readily solubilized by bacteri

294 ten-3-ol formed in reaction of linoleate 10S-hydroperoxide with hematin or ferrous ions.

295 Intriguingly, the reaction of lithium hydroperoxide with triiodide exhibits a faster kinetics,

296 actions of primary and secondary propargylic hydroperoxides with a variety of nucleophiles including

297 approach, the rate constants for amino acid hydroperoxides with ebselen, a glutathione peroxidase mi

298 of the controlled reactivity of propargylic hydroperoxides with external nucleophiles under gold cat

299 s show that these reactions form substituted hydroperoxides with no energy barrier.

300 products of cholesterol, namely 25- and 20xi-hydroperoxides, with the four principal cholesterol-meta