ライフサイエンスコーパス: hydrophila

1 detailed mechanisms of action of Act from A. hydrophila.

2 d by the closely related bacterium Aeromonas hydrophila.

3 DNA of a diarrheal isolate SSU of Aeromonas hydrophila.

4 activities of a diarrheal isolate SSU of A. hydrophila.

5 lay an important role in the virulence of A. hydrophila.

6 fying a predicted effector TseC in Aeromonas hydrophila.

7 o cholerae, Vibrio vulnificus, and Aeromonas hydrophila.

8 a lethal challenge dose of wild-type (WT) A. hydrophila.

9 cB) from a clinical isolate SSU of Aeromonas hydrophila.

10 from a diarrheal isolate, SSU, of Aeromonas hydrophila.

11 ch could alter the virulence potential of A. hydrophila.

12 e IIH R-M system from the pathogen Aeromonas hydrophila.

13 from the diarrheal isolate SSU of Aeromonas hydrophila.

14 ild-type (WT) and complemented strains of A. hydrophila.

15 nses to a cytotoxic enterotoxin of Aeromonas hydrophila.

16 ositive or -negative background strain of A. hydrophila.

17 ious virulence factors produced by Aeromonas hydrophila, a type II secretion system (T2SS)-secreted c

18 one at 10 microM in overnight cultures of A. hydrophila abolishes exoprotease production in azocasein

19 lates the most-potent virulence factor of A. hydrophila, Act.

20 ere, we demonstrate that one such, Aeromonas hydrophila AhQnr, is soluble, stable, and relieves quino

21 These data add A. hydrophila and A. salmonicida to the growing family of g

22 ent culture supernatants from both Aeromonas hydrophila and Aeromonas salmonicida activate a range of

23 Act is a potent virulence factor of A. hydrophila and has been shown to contribute significantl

24 secreted by the bacterial pathogen Aeromonas hydrophila and is capable of killing target cells by for

25 ibrio cholerae, Vibrio vulnificus, Aeromonas hydrophila and other Gram-negative bacteria.

26 ulence of diarrheal isolate SSU of Aeromonas hydrophila and showed that VasH, a sigma(54) activator a

27 a correlation between the TTSS and Act of A. hydrophila and the production of lactones.

28 the environmental isolate ATCC 7966(T) of A. hydrophila and the vacB gene of Shigella flexneri.

29 the T3SS from a diarrheal isolate, SSU of A. hydrophila, and defined the role of some regulatory gene

30 ted in 1971 from the fish pathogen Aeromonas hydrophila, and of the cryptic IncA/C plasmid pRAx (49,7

31 ion from Photorhabdus luminescens, Aeromonas hydrophila, and Vibrio parahaemolyticus are also sensiti

32 the TTSS translocon, from wild-type (WT) A. hydrophila as well as from a previously characterized cy

33 ic groups receiving an infusion of Aeromonas hydrophila at 0.2 mL/kg/hr, gradually increasing to 0.4

34 The complete genome of Aeromonas hydrophila ATCC 7966(T) was sequenced.

35 lase from diarrheal isolate SSU of Aeromonas hydrophila bound to human plasminogen and facilitated th

36 as then introduced into the chromosome of A. hydrophila by using the suicide vector pJQ200SK, allowin

37 hat only the full-length ACD of RtxA from A. hydrophila catalyzed the covalent cross-linking of the h

38 hand, the WT and complemented strains of A. hydrophila caused 80 to 90% of the mice to succumb to in

39 Inactivation of the ahyI gene on the A. hydrophila chromosome abolishes C4-HSL production.

40 2.6-kb SalI/HindIII DNA fragment from an A. hydrophila chromosome was cloned and sequenced.

41 Members of the Aeromonas hydrophila complex (A. hydrophila, HG2, and A. salmonici

42 The exoprotease activity of A. hydrophila consists of both serine protease and metallop

43 environmental isolate ATCC 7966 of Aeromonas hydrophila consists of six genes (rtxACHBDE) organized i

44 d 100% of the animals inoculated with the A. hydrophila control strain.

45 regulation in the fur isogenic mutant of A. hydrophila could be restored by complementation.

46 se in gidA and act gene expression in the A. hydrophila Dam-overproducing strain, and these data matc

47 Three enterotoxins from the Aeromonas hydrophila diarrheal isolate SSU have been molecularly c

48 n, we showed that animals challenged with A. hydrophila die because of kidney and liver damage, hypog

49 ps), Pseudomonas aeruginosa (xcp), Aeromonas hydrophila (exe), and Vibrio cholerae (eps).

50 splayed 87% sequence similarity to Aeromonas hydrophila ExeE, a member of the PulE (GspE) family of p

51 The tagA gene of A. hydrophila exhibited 60% identity with that of a recentl

52 In contrast, the wild-type (WT) A. hydrophila exhibited significant growth at this low temp

53 ction with ciprofloxacin-resistant Aeromonas hydrophila following leech therapy.

54 ntation experiments demonstrated that the A. hydrophila fur gene could restore iron regulation in an

55 is more similar to the X. campestris than A. hydrophila genes.

56 Thus, the A. hydrophila genome sequence provides valuable insights in

57 An A. hydrophila genomic library was transferred into a P. aer

58 bers of the Aeromonas hydrophila complex (A. hydrophila, HG2, and A. salmonicida), a group that has p

59 le aspects of the metabolic repertoire of A. hydrophila include dissimilatory sulfate reduction and r

60 ablished a role for three enterotoxins in A. hydrophila-induced gastroenteritis in a mouse model with

61 tropenic animals were more susceptible to A. hydrophila infection than normal mice.

62 e and enhances their survivability during A. hydrophila infection.

63 mice with the above AHLs prior to lethal A. hydrophila infection.

64 predominant immune cells inflicted during A. hydrophila infections, such as murine macrophages, when

65 (n = 5), which received continuous Aeromonas hydrophila infusion plus antiprostacyclin antibody infus

66 from a diarrheal isolate, SSU, of Aeromonas hydrophila is aerolysin related and crucial to the patho

67 Aeromonas hydrophila is both a human and animal pathogen, and the

68 sport in the fresh water bacterium Aeromonas hydrophila is found to occur by means of an indiscrimina

69 ion of the S-layer on the cell surface in A. hydrophila is more similar to the X. campestris than A.

70 , 1 Serratia marcescens isolate, 1 Aeromonas hydrophila isolate, 1 Aeromonas veronii isolate, 2 Chrys

71 In contrast, WT A. hydrophila killed 100% of the mice within 48 h.

72 ansit through turtles colonized by Aeromonas hydrophila, leading to the hypothesis that SdiA is used

73 Aeromonas hydrophila leads to both intestinal and extraintestinal

74 f the effector domains of V. cholerae and A. hydrophila MARTX toxins to elucidate the mechanism of th

75 The biological activity of selected A. hydrophila mutants was restored after complementation.

76 ure supernatants from deletion mutants of A. hydrophila, namely, a Delta act mutant (a T2SS-associate

77 ndividual with multiple strains of Aeromonas hydrophila (NF1-NF4), the latter three constituted a clo

78 rosenbergii nodovirus), bacteria (Aeromonas hydrophila or Vibrio harveyi) or heavy metals (cadmium o

79 ages (44RR2.8t, 25 and 31) and one Aeromonas hydrophila phage (Aeh1).

80 The A. hydrophila pilD homologue, tapD, was identified by its a

81 nstrated for the first time that VgrG1 of A. hydrophila possessed actin ADPRT activity associated wit

82 Our study is the first to report that A. hydrophila possesses a functional RtxA having an ACD tha

83 ted cytotoxic enterotoxin (Act) of Aeromonas hydrophila possesses multiple biological activities, whi

84 A cytotoxic enterotoxin (Act) of Aeromonas hydrophila possesses several biological activities, and

85 A cytotoxic enterotoxin (Act) of Aeromonas hydrophila possesses several biological activities, indu

86 totoxic, actin-targeting mART from Aeromonas hydrophila PPD134/91.

87 e pathogens, including a strain of Aeromonas hydrophila resistant to amikacin, tobramycin, and multip

88 Overproduction of mutated Dam in A. hydrophila resulted in bacterial motility, hemolytic and

89 The A. hydrophila RNase R-lacking strain was found to be less v

90 er, we showed that the full-length ACD of A. hydrophila RtxA disrupted the actin cytoskeleton of HeLa

91 Aeromonas hydrophila secretes several extracellular proteins that

92 the DNA adenine methyltransferase gene of A. hydrophila SSU (dam(AhSSU)) in a T7 promoter-based vecto

93 ntially be important for the viability of A. hydrophila SSU as we could delete the chromosomal copy o

94 cid residues ((252)FYDAEKKEY(260)) in the A. hydrophila SSU enolase involved in plasminogen binding.

95 -expressed enolase in the pathogenesis of A. hydrophila SSU infections and of any gram-negative bacte

96 shed by 55% compared to that of a control A. hydrophila SSU strain harboring the pBAD vector alone.

97 ctively, compared to those of the control A. hydrophila SSU strain.

98 gene to be essential for the viability of A. hydrophila SSU, and, therefore, to better understand the

99 e bacterium, and overproduction of Dam in A. hydrophila SSU, using an arabinose-inducible, P(BAD) pro

100 e the expression of act and gidA genes in A. hydrophila SSU.

101 e act/aopB mutant, compared to that of WT A. hydrophila SSU.

102 erated a fur isogenic mutant of wild-type A. hydrophila SSU.

103 343, 394, 420, 427, and 430 of enolase in A. hydrophila SSU; the mutated forms of enolase were hypere

104 nd lateral flagellin proteins from Aeromonas hydrophila strain AH-3 (serotype O34) were found to be g

105 ral flagellum, that are reported in other A. hydrophila strains are not identified in the sequenced i

106 was used, whereby either single or mixed A. hydrophila strains were injected intramuscularly.

107 We purified A. hydrophila TagA as a histidine-tagged fusion protein (rT

108 il gene cluster that resembles the Aeromonas hydrophila tap gene cluster and other type IV-A pilus as

109 Pseudomonas aeruginosa (PilA), and Aeromonas hydrophila (TapA).

110 ns of a diarrheal isolate, SSU, of Aeromonas hydrophila that exhibited a 50 to 53% reduction in the h

111 was noted in the gidA isogenic mutant of A. hydrophila that was generated by marker exchange mutagen

112 In Aeromonas hydrophila, the ahyI gene encodes a protein responsible

113 against Edwardsiella ictaluri and Aeromonas hydrophila, the causative agents of enteric septicemia o

114 d secretion compared to that of wild-type A. hydrophila; the triple-knockout mutant failed to induce

115 ic enterotoxin gene (act)-minus strain of A. hydrophila, thus generating aopB and act/aopB isogenic m

116 the cytotoxic enterotoxin (Act) of Aeromonas hydrophila to examine global cellular transcriptional re

117 EpsL and its homologue, ExeL, from Aeromonas hydrophila together with either EpsE or its Aeromonas ho

118 The tagA isogenic mutant of A. hydrophila, unlike its corresponding wild-type (WT) or t

119 The A. hydrophila VacB protein contained 798 amino acid residue

120 ogether, our data indicated alteration of A. hydrophila virulence by overproduction of Dam.

121 f RNase R in modulating the expression of A. hydrophila virulence.

122 m was essential for attenuation of Aeromonas hydrophila virulence.

123 An Aeromonas hydrophila VolA homolog complements a V. cholerae VolA m

124 The RNase R of A. hydrophila was a cold-shock protein and was required for

125 e cytotoxic enterotoxin (Act) from Aeromonas hydrophila was hyperexpressed with the pET, pTRX, and pG

126 ol group (n = 6), in which 1010/mL Aeromonas hydrophila was infused intravenously at 0.2 mL.kg-1.hr-1

127 well as from the clinical isolate SSU of A. hydrophila, was exclusively expressed and produced durin

128 viability of Escherichia coli and Aeromonas hydrophila were compared to spherical nanostructures (an