ライフサイエンスコーパス: hydrophilicity

1 to the increased negative surface charge and hydrophilicity.

2 up, which is weakly hydrated to decrease its hydrophilicity.

3 acy against solid tumors, perhaps due to its hydrophilicity.

4 and their net negative molecular charge and hydrophilicity.

5 axially reflecting the underlying pattern of hydrophilicity.

6 in maintaining its detergent solubility and hydrophilicity.

7 esting that faster transfer reflects greater hydrophilicity.

8 rease, substantially, with increasing facial hydrophilicity.

9 within the cell, strong bacisity, and medium hydrophilicity.

10 creased, with continuous increases in facial hydrophilicity.

11 er at room temperature returned its original hydrophilicity.

12 f GPI modification decreases with increasing hydrophilicity.

13 ther headgroups in-plane, decreasing surface hydrophilicity.

14 We also studied other regions of high hydrophilicity.

15 re solvent-accessible and increasing surface hydrophilicity.

16 act with generated NO2, which also increases hydrophilicity.

17 ion but increases NO2 surface reactivity and hydrophilicity.

18 e exposure to solvent, degree of freedom and hydrophilicity.

19 per unit area of fabric and decreasing yarn hydrophilicity.

20 atrix affecting e.g. its binding ability and hydrophilicity.

21 three modules: a PEG single chain to promote hydrophilicity, a dihydrolipoic acid (DHLA) unit connect

22 ller alkaline earth metal cation with higher hydrophilicity across the membrane/water interface, ther

23 study the effects of peptide hydrophobicity/hydrophilicity, amphipathicity, and helicity (induced by

24 Comparative hydrophilicity analysis of predicted PapG peptides revea

25 Hydrophilicity analysis of the deduced aa sequence indic

26 Hydrophilicity analysis of this adult MyHC amino-acid se

27 so known as typical LEA proteins, shows high hydrophilicity and a high percentage of glycine and othe

28 tutions resulted in analogues with increased hydrophilicity and a lesser propensity to form gels in a

29 tion of nonvolatile chemicals with increased hydrophilicity and addition of OH.

30 cular structure of the Gd-HOPO-TAM chelates (hydrophilicity and aromatic group substitution) signific

31 length is a very common strategy to tune the hydrophilicity and biocompatibility of such materials, m

32 illogenesis and mean beta-strand propensity, hydrophilicity and charge of the amino acid sequences.

33 -R1 through IMP-R8) that differed in overall hydrophilicity and charge were compared.

34 ofouling-resistant surfaces based on surface hydrophilicity and charge, biomolecule functionalization

35 1T MoS2 layers are mainly a result of their hydrophilicity and high electrical conductivity, as well

36 Four sites were selected based on hydrophilicity and high sequence variability identified

37 among strains, overall predicted regions of hydrophilicity and hydrophobicity in the extracellular d

38 ormation in terms of separation according to hydrophilicity and hydrophobicity, respectively.

39 Key sorbent properties included the sorbent hydrophilicity and hydrophobicity, surface pKa of the so

40 ite membranes (GO-TFC) increased the surface hydrophilicity and imparted antimicrobial activity to th

41 irradiation of PC surfaces increases surface hydrophilicity and increases EOF.

42 os and high limits of detection due to their hydrophilicity and lack of basic sites able to be proton

43 e polymer in order to compensate for peptide hydrophilicity and maintain gelation capability below ph

44 The hydrophilicity and negative charge of the pore surface g

45 emical properties (overall hydrophobicity or hydrophilicity and net charge of -1, or 0, or +1), and y

46 ptide sequences and the calculated values of hydrophilicity and net molecular charge.

47 e prediction model was established using the hydrophilicity and peptide length of 153 di- to tetrapep

48 35 properties of amino acid content, charge, hydrophilicity and polarity for the quantitative predict

49 The high hydrophilicity and polyvalency properties of the Flexime

50 d observed considerable enhancements in both hydrophilicity and redox activity during reaction.

51 We quantitatively characterized the hydrophilicity and redox activity of squalene before and

52 e the non-trivial interplay between nanopore hydrophilicity and surface barriers on the overall water

53 Surface hydrophilicity and surface roughness were also maintaine

54 on is based on electrostatic repulsion, high hydrophilicity and the steric hindrance provided by the

55 The extent of hydrophilicity and the surface charge could not explain

56 ted to differences in the catalysts' initial hydrophilicity and their proclivity to react with genera

57 proved the membrane active layer in terms of hydrophilicity and transport properties without adversel

58 e of mutant channels was highly dependent on hydrophilicity and volume of the amino acid substituted

59 ansferase is an effective means to alter the hydrophilicity and/or nucleophilicity of a molecule.

60 orosity, surface morphology, surface charge, hydrophilicity, and mechanical properties of PES/AG memb

61 We show that the effective pore size, hydrophilicity, and organophilicity of ZIFs can be conti

62 particles with different diameters, surface hydrophilicity appears to mediate early clearance.

63 rface properties revealed that roughness and hydrophilicity are likely prominent parameters for drivi

64 no terminal function characterized by higher hydrophilicity are required for a good and selective inh

65 oenvironments using the local hydrophobicity/hydrophilicity around each residue of the protein.

66 hosphorylation is related to the increase in hydrophilicity around serines 303 and 304 or that activa

67 gluconic acid, we changed the hydrophobicity/hydrophilicity around the active sites and fine-tuned th

68 e was quantified by calculating the relative hydrophilicity around the replacing amino acid residue.

69 ded increased water solubility and polyester hydrophilicity as well as shorter diol chain lengths.

70 ino acids results in peptides with increased hydrophilicity (as determined by elution times on C18 si

71 Reinforced hydrophilicity assists liquid spreading and capillarity-

72 ic at time zero, functionalization increased hydrophilicity at equilibrium.

73 onformation, compact size, and lipophilicity/hydrophilicity balance observed in the bridged compounds

74 and as biomaterials that exhibit exceptional hydrophilicity, biocompatibility, and antifouling proper

75 SRT1720 increased hepatic BA hydrophilicity by increasing tri- and tetrahydroxylated

76 es was found to increase the surface charge, hydrophilicity (by 20%), porosity (by 77%) and permeate

77 encapsulated (to improve their stability and hydrophilicity) by spray-drying, using maltodextrin cros

78 mmon solvents depending on hydrophobicity or hydrophilicity can be controlled by chemical functionali

79 that surface functionalization for increased hydrophilicity can not only improve the performance of C

80 that PrP(C) helix 1 has certain properties (hydrophilicity, charge distribution) that make it unique

81 However, PHAs need to have tunable hydrophilicity, chemical functionalities, and appropriat

82 of thiazole-tethered pyrazoles with improved hydrophilicity compared to bithiazoles.

83 ovel MMPIs are characterized by an increased hydrophilicity compared with the lead structures and exc

84 ition, and while the PCL fibers lend a local hydrophilicity (contact angle theta=74 degrees ) for suf

85 ple pore residues in BK displayed side-chain hydrophilicity-dependent constitutive openness, we propo

86 Modification of their hydrophilicity did not change the suitability of the pol

87 rs that reflect different hydrophobicity and hydrophilicity distribution patterns along a protein cha

88 he channel approaches that of water, channel hydrophilicity dominated water conduction energetics.

89 orescence-based assessment of plasma-induced hydrophilicity (FAPH), that enables spatial mapping of t

90 monium group, are found to be high intrinsic hydrophilicity, favorable charge-dipole alignment, and--

91 Instead, balance between lipophilicity and hydrophilicity had a greater influence.

92 In particular, hydrophilicity has a strong influence on retention, with

93 en synthesized in which the degree of facial hydrophilicity has been systematically varied.

94 Substrate hydrophobicity/hydrophilicity has previously been shown to affect the m

95 hydroxylated PBDEs (OH-PBDEs), with greater hydrophilicity, have different concentrations in materna

96 ts, and superior surface properties, such as hydrophilicity, high surface energy, and high density le

97 and then eluted from the LC column covered a hydrophilicity/hydrophobicity range that included an est

98 on of pore dimensions, chemical composition (hydrophilicity/hydrophobicity), crystal size and orienta

99 sign and illustrate the importance of linker hydrophilicity in making nonaggregated, active mAb-MGB c

100 r oxygens or with 4 ether oxygens to promote hydrophilicity in orienting LB monolayers, and alkyl swa

101 to potentially achieve specificity and lower hydrophilicity in the design of inhibitors targeting DEN

102 dence is presented to show that increases in hydrophilicity in the distal heme pocket can decrease ox

103 individual ChOOHs increased with increasing hydrophilicity in the following order: 6beta-OOH < 6alph

104 preference for acidic residues and increased hydrophilicity in the regions immediately up- or downstr

105 controlled by the combination of side chain hydrophilicity, ionization state, and ability to positio

106 lyl ethers form on the particle surface, the hydrophilicity is decreased, significantly altering the

107 sed to form the hydrophobic brush, while the hydrophilicity is maintained by polyethylene glycol (PEG

108 alphavbeta3 (IC50 = 620 nM) and a pronounced hydrophilicity (log D = -4.2).

109 l poses an analytical challenge due its high hydrophilicity, low volatility, charge neutrality over a

110 cterization, we concluded that the degree of hydrophilicity may control heterogeneous nucleation on q

111 Increased hydrophilicity may reduce non-specific binding in the un

112 nds tested based on their hydrophobicity and hydrophilicity molecules as well as the molecular weight

113 inhibitory signal (NIS) contains a conserved hydrophilicity motif, which forms an amphipathic helix.

114 ies of graphene oxide (GO), such as the high hydrophilicity, negative charge, strong adsorption capab

115 ability by increasing the zeta potential and hydrophilicity of CeO2 NPs.

116 The hydrophilicity of diol functionalities originating from

117 Meanwhile, increase in overall hydrophilicity of GNGA carriers leads to fast polymer de

118 factant was used to increase wettability and hydrophilicity of graphene; thereby facilitating the ass

119 olestatic liver injury in mice by increasing hydrophilicity of hepatic BA composition and decreasing

120 er molecule and protein, and the density and hydrophilicity of neighboring protein atoms.

121 atter (NOM) conditioning films, owing to the hydrophilicity of NOM.

122 reted as a consequence of differences in the hydrophilicity of PEDOT(PSS) in contact with the substra

123 The apparent hydrophilicity of peptides was determined as a function

124 The hydrophilicity of phenolic compounds might prevent drug

125 - charge, polarity, color (UV-vis range) and hydrophilicity of polymers, polymer functionalized surfa

126 This association was modified by the hydrophilicity of statin and the age of the subject.

127 tic enhancement and polarity, hydropathy, or hydrophilicity of substituents.

128 ), that enables spatial mapping of the local hydrophilicity of surfaces normally inaccessible by trad

129 tations which will increase the size and the hydrophilicity of the "Anfinsen cage," the enclosed cavi

130 nds showed a correlation with the side-chain hydrophilicity of the 307 residue.

131 The rough microstructure combined with the hydrophilicity of the aerogel ensures its excellent unde

132 that the distribution of hydrophobicity and hydrophilicity of the amino acid residues along a protei

133 erns hydrolysis on the basis of the size and hydrophilicity of the amino acid side chain.

134 modification is attributed to changes in the hydrophilicity of the base and its impact on major groov

135 Hydrophilicity of the bile acid pool is associated with

136 hronic bile acid treatment by increasing the hydrophilicity of the bile acid pool.

137 Hydrophilicity of the bile salt pool, controlled by FXR

138 are complex and depend on the hydrophobicity/hydrophilicity of the carbon surface.

139 spontaneously with aqueous buffer due to the hydrophilicity of the coating.

140 ed around the oxazole moiety to increase the hydrophilicity of the compounds and to correlate the bio

141 droxymethyluracil alters the flexibility and hydrophilicity of the DNA molecules, which may account f

142 adecanesulfonate and lucigenin decreased the hydrophilicity of the dye, increased its partition rate

143 The size of the pores and the hydrophilicity of the environment make C-S-H gel an exce

144 ead derives from mutations that increase the hydrophilicity of the former light chain interface by re

145 specifically to tune the hydrophobicity and hydrophilicity of the LIG surfaces.

146 PSS increases the hydrophilicity of the membrane and increases the negativ

147 one to hydroxyl radicals and increase of the hydrophilicity of the membrane surface.

148 o its inability to sufficiently diminish the hydrophilicity of the multiply charged PS headgroup.

149 without mimicking the structure or increased hydrophilicity of the phosphorylated residues.

150 We also demonstrate that the hydrophilicity of the polymeric constituents of a resin

151 ect of drug binding by either increasing the hydrophilicity of the pore or weakening helix-helix pack

152 ed from several mutations that increased the hydrophilicity of the protein surface, thereby decreasin

153 rrelation (R(2) = 0.93) between the relative hydrophilicity of the replaced amino acid and the protei

154 t these unique residues in Vav1 increase the hydrophilicity of the rim of the binding pocket, impairi

155 ing specific DNA affinity with an increasing hydrophilicity of the side chain of residue 138.

156 d derivatives to evaluate how increasing the hydrophilicity of the steroid nucleus affects the abilit

157 Following oxygen plasma treatment, the hydrophilicity of the surface of TPE increases (determin

158 med by Gly35 of CDR1, thereby increasing the hydrophilicity of the V(H):V(L) interface.

159 Hydrophilicity of these analogues, a potential measure o

160 chemically deposited PEDOT(PSS)-films on the hydrophilicity of these films has been documented by con

161 versus Shaker Kv channels is produced by the hydrophilicity of two "speed-control" residues located i

162 ouble emulsion step was performed due to the hydrophilicity of xylitol.

163 graphene, regardless of the hydrophobicity (hydrophilicity) of the substrate.

164 Ps grafted with polymer brushes of different hydrophilicity on Au and Fe3 O4 surfaces separately.

165 ium phosphate buffer at pH 7.0 (a measure of hydrophilicity) or affinity in an in vitro human GnRH re

166 The amino acid sequence and hydrophilicity plot predicted that the A33R gene product

167 Hydrophilicity plots of BaiG show a high degree of simil

168 Hydrophilicity plots of the OPTs suggest that they are i

169 urements for the attributes of volume, area, hydrophilicity, polarity, hydrogen bonding, shape, and c

170 of maintaining a balanced hydrophobicity and hydrophilicity profile in developing effective LpxC-targ

171 e separated into two classes on the basis of hydrophilicity profiles, sequence similarities, and reac

172 sorption demonstrated that this coating adds hydrophilicity, redox-active moieties, and additional me

173 im of achieving better specificity and lower hydrophilicity than those of current scaffolds in the de

174 longer retention times on HPLC (a measure of hydrophilicity) than degarelix were identified.

175 e leading edge; it is this sharp gradient in hydrophilicity that drives the transport of hydrophilic

176 rand provide a pattern of hydrophobicity and hydrophilicity that matches that of the pentapeptide "up

177 With its high-molecular weight and hydrophilicity, this conjugate is designed to selectivel

178 Increasing the hydrophilicity through replacement of a particular methy

179 jacent steric hindrance modulate this hidden hydrophilicity, thus making this scaffold a good candida

180 ting a macrovoid-free structure and inducing hydrophilicity to bring about higher water fluxes.

181 operties, such as the polar surface area and hydrophilicity, to reduce the central activity observed

182 ydroxyl-) and strong (i.e., sulfate-) facial hydrophilicity, using Cascade Blue as the fluorophore.

183 physicochemical properties: hydrophobicity, hydrophilicity, volume, surface area, bulkiness and refr

184 Surface hydrophilicity was assessed over 4 weeks by measuring th

185 A series of molecules of increasing hydrophilicity was constructed, and the transport of the

186 Further nitrogen doping greatly improves the hydrophilicity, which boosts the supercapacitive perform

187 rease in mean helical content with increased hydrophilicity, which occurs predominantly through reduc

188 g requirements of aggregation propensity and hydrophilicity, which resulted in a set of design rules

189 ium correlated with its naturally decreasing hydrophilicity, which was not observed for the nickel an

190 ery, we have investigated ways of increasing hydrophilicity while retaining high potency and lack of

191 luted from the column in decreasing order of hydrophilicity, with the more highly sulfated structures

192 ere found to decrease with increasing facial hydrophilicity; with a membrane of intermediate thicknes

193 membrane physicochemical properties (surface hydrophilicity, zeta potential, and morphology), membran