ライフサイエンスコーパス: hydrophobic domain

1 antimicrobial constituents to the separated hydrophobic domain.

2 drophilic domain and a cation channel in its hydrophobic domain.

3 o the ER membrane by virtue of an N-terminal hydrophobic domain.

4 res by precluding exposure of the underlying hydrophobic domain.

5 r through the masking of an N-terminal Kv4.2 hydrophobic domain.

6 etergent micelle envelope that surrounds the hydrophobic domain.

7 thic helices face each other, thus forming a hydrophobic domain.

8 sites of palmitoylation in proximity to the hydrophobic domain.

9 ide of a central, relatively well conserved, hydrophobic domain.

10 r side-chain substitution for optimizing the hydrophobic domain.

11 H3, and BH4) regions and a carboxyl-terminal hydrophobic domain.

12 BH3, and BH4 regions and a carboxyl-terminal hydrophobic domain.

13 ed at Thr308 in the T-loop and Ser473 in the hydrophobic domain.

14 ta-specific p100 form lacking the N-terminal hydrophobic domain.

15 integral protein via a central 19 amino acid hydrophobic domain.

16 terminal cytoplasmic domain and a C-terminal hydrophobic domain.

17 placed by a mutant containing a heterologous hydrophobic domain.

18 stable N-terminal domain and the C-terminal hydrophobic domain.

19 ine/serine-rich domain, and carboxy-terminal hydrophobic domain.

20 en the atomic force microscope probe and the hydrophobic domains.

21 cyclases dimerize (or oligomerize) via their hydrophobic domains.

22 from a single Trp inserted into the extended hydrophobic domains.

23 t channels and were influenced by the second hydrophobic domains.

24 e linkages to tether either the polar or the hydrophobic domains.

25 ester linkages to tether both the polar and hydrophobic domains.

26 nd 150), one of which is located between the hydrophobic domains.

27 that contains no obvious signal sequence or hydrophobic domains.

28 ss-sectional areas occupied by the polar and hydrophobic domains.

29 c interaction and leading to the exposure of hydrophobic domains.

30 its substrates that may be collapsed inside hydrophobic domains.

31 nding, possibly by masking otherwise exposed hydrophobic domains.

32 s were used to determine surface versus bulk hydrophobic domains.

33 n of their surfaces with a simple pattern of hydrophobic domains.

34 s activity being regulated by the C-terminal hydrophobic domain 1 (HD1) of GDAP1 in an autoinhibitory

35 ylation of a cysteine in the most C-terminal hydrophobic domain (1).

36 It contains two internal hydrophobic domains (34 residues each) that have enough

37 n allowed the hydrophilic region between the hydrophobic domains (354-408) to cross the bilayer.

38 Furthermore, we found that the Tat hydrophobic domain (aa 36-47) mediated formation of two

39 The NS3/NS3A proteins have two hydrophobic domains (aa 118 to 141 and 162 to 182) and t

40 l anchor site, located before the C-terminal hydrophobic domain (alpha(2)delta-1DeltaC-term).

41 Another hydrophobic domain (amino acids 241-265), which is relat

42 patial distribution of positively charged or hydrophobic domains among CTX A2, A3, and A4 could lead

43 MP1, predicted a 548-amino-acid protein with hydrophobic domains, an amino-terminal SH3-binding domai

44 ncoded by the HIV-1 genome with a N-terminal hydrophobic domain and a C-terminal hydrophilic domain.

45 only 97 residues and contains an N-terminal hydrophobic domain and a C-terminal hydrophilic domain;

46 ll have similar structures, with a trimethyl hydrophobic domain and a polar or charged headgroup.

47 with purified VP4, we found that the central hydrophobic domain and a proximal C-terminal nuclear loc

48 eins share a conserved 70 amino acid residue hydrophobic domain and are related structurally to the s

49 is restored by the substitution of the third hydrophobic domain and carboxyl terminus of 5-lipoxygena

50 on Gram-positive bacteria have a C-terminal hydrophobic domain and charged tail, preceded by a conse

51 rotein of 117 amino acids with an N-terminal hydrophobic domain and four invariant cysteines.

52 that specific interactions between the NS5B hydrophobic domain and other membrane-bound factors may

53 oli cells as a truncated protein lacking the hydrophobic domain and purified to homogeneity.

54 -human chimera with only the most C-terminal hydrophobic domain and the C-terminus of the transporter

55 f this signal depends on the polarity of the hydrophobic domain and the sequence KQS in the short hyd

56 Caveolin-1 has a 33-amino acid hydrophobic domain and three sites of palmitoylation in

57 SipB membrane integration required both the hydrophobic domains and an additional helical C-terminal

58 nine cleavage sites are typically located in hydrophobic domains and cleavage at these points reduces

59 Both bolas have similar hydrophobic domains and contain either one, in GLH-58, o

60 GDE1 encodes a 331-residue protein with two hydrophobic domains and contains a GDE domain that share

61 Similar patterns of hydrophobic domains and cysteines in all known gM and U(

62 Wild type flotillin-1 has two putative hydrophobic domains and is localized to lipid raft micro

63 ibited by targeted disruptions of individual hydrophobic domains and the loss of membrane disruption

64 g hydrophilic residues within the C-terminal hydrophobic domain, and amino acid substitutions that al

65 C-terminal 217 amino acids, one bound to the hydrophobic domain, and one bound to either the hydropho

66 to the L18 domain, that cpSRP54 binds to the hydrophobic domain, and that LHCP and cpSRP54 independen

67 a brucei enzymes, which have a COOH-terminal hydrophobic domain, and the other contains the human, S.

68 ly long, at 58 amino acids, and contains two hydrophobic domains, and its sequence is highly conserve

69 al domain, the linker domain between the two hydrophobic domains, and the C-terminal domain.

70 ture of phospholamban is "L-shaped" with the hydrophobic domain approximately perpendicular to the cy

71 gion 2 (amino acids 301-500), with a smaller hydrophobic domain ( approximately 50 residues).

72 ons suggested that E3-10.9K orthologs with a hydrophobic domain are integral membrane proteins.

73 econd and third transmembrane domains, and a hydrophobic domain are required for interaction with cpS

74 hat the methyl groups of the leucines of the hydrophobic domains are also affected by the substitutio

75 Our data reveal that elastin-like hydrophobic domains are composed of transient beta-turns

76 n is found at the cell surface and that both hydrophobic domains are required for cell surface target

77 Therefore, these defined hydrophobic domains are sufficient to direct native and

78 rst 40 amino acids of PpPas2p, devoid of the hydrophobic domains, are sufficient to target a soluble

79 ) a hemopexin-like domain, (vi) a 24-residue hydrophobic domain as a potential transmembrane domain,

80 Due to its 17-mer hydrophobic domain at its C terminus, mT4 is a membrane-

81 yR) is a large homotetrameric protein with a hydrophobic domain at the C-terminal end that resides in

82 ATRAP contains three hydrophobic domains at the amino-terminal end of the pro

83 an amphiphilic 4-helix bundle peptide with a hydrophobic domain based on a synthetic ion channel and

84 of the nonpolar probe Nile red indicate that hydrophobic domains become available for probe partition

85 to 474 or 265 to 474, including the internal hydrophobic domain, bind to cellular membranes but are n

86 ystallinity of the poly(tetrafluoroethylene) hydrophobic domains both as a function of EW and membran

87 The hydrophobic domain, but no specific sequence therein, wa

88 ve membrane-spanning segments (MSSs) in this hydrophobic domain; but to date, there is little experim

89 TNS fluorescence, suggesting the exposure of hydrophobic domains by toxin B.

90 Two hydrophobic domains can be distinguished which may be in

91 While the first six hydrophobic domains can be readily modeled as convention

92 ng by Get3 and suggest general principles of hydrophobic domain chaperoning by cellular targeting fac

93 self-assembly is promoted by association of hydrophobic domains contained within the tropoelastin se

94 intracellular N and C termini and a central hydrophobic domain containing 12 membrane-spanning segme

95 Each of these extended hydrophobic domains contains a centrally located single

96 mutant of CED-9 lacking the carboxy-terminal hydrophobic domain could associate with CED-4 and block

97 t-specific conformational flexibility of the hydrophobic domain created by SP-B folding may explain t

98 ength sequence without the signal and anchor hydrophobic domains (CSPDeltaHP).

99 The hydrophobic domain deletion mutant significantly weakene

100 In contrast to that of PHV, the NY-1V hydrophobic domain directs the proteasomal degradation o

101 sed of UPy-UPy dimers embedded in segregated hydrophobic domains dispersed within the PEG matrix as c

102 EGFP-tagged E3-4.8K, which lacked the hydrophobic domain, displayed diffuse cellular localizat

103 acid), located between the second and third hydrophobic domains (domain II) in the cytoplasmic side

104 The signal is characterized by a moderately hydrophobic domain downstream from the cleavage/modifica

105 Both proteins are predicted to have two hydrophobic domains, each capable of spanning the membra

106 We conclude that the hydrophobic domain encoded by tim23C targets Tim23p to t

107 In particular the second hydrophobic domain encoded within the fourth exon is hig

108 erminus of the peptide and the presence of a hydrophobic domain exhibiting an estimated log P4.0.

109 These two hydrophobic domains flank a large hydrophilic region tha

110 cteristic predicted N-terminal alpha-helical hydrophobic domain followed by basic amino acids and pro

111 SLP-2 lacks a characteristic NH(2)-terminal hydrophobic domain found in other stomatin homologues an

112 The highly hydrophobic domain (FQRQVWLLF) interacts with caveolin 1

113 Removal of a COOH-terminal hydrophobic domain from GFP-Bax inhibited redistribution

114 complex, chimera I1G2(M), which contains the hydrophobic domain from GIRK2, exhibits normal K+ select

115 cleavage event that selectively removes the hydrophobic domain from the AAA+ domain of TorsinA, whic

116 ediate unfolded state or help to recover the hydrophobic domains from the completely unfolded state.

117 entify possible membrane domains, individual hydrophobic domains from VP2 and VP3 were expressed in a

118 We find that the hydrophobic domains generated by the polymer not only re

119 ri-partite structure consisting of a central hydrophobic domain (h-domain), and two flanking polar do

120 constructed a mutant of gpNu1 in which this hydrophobic "domain" has been deleted in order to test t

121 y occurring peptides containing cationic and hydrophobic domains have evolved to interact with mammal

122 of the flexible N terminus, specifically the hydrophobic domain (HD) or the central region (CR).

123 cytoplasmic basic region, and an N-terminal hydrophobic domain (HD) that was hypothesized to functio

124 CoV E has a single hydrophobic domain (HD), is targeted to Golgi complex me

125 sential for the alpha-cleavage to occur is a hydrophobic domain (HD).

126 rwise pathogenic PrP mutants in a downstream hydrophobic domain (HD).

127 shown that residues in the loops connecting hydrophobic domain (HD)3 and HD4 and HD7 and HD8 are acc

128 three leucines at the C-terminal side of its hydrophobic domain; however, deletion of three valines f

129 peptide correspond to the protease-sensitive hydrophobic domains identified in earlier biochemical st

130 anchored to the membrane via its N-terminal hydrophobic domain, (ii) can co-assemble with catalytica

131 of the prion protein (PrP) that include the hydrophobic domain implicated in the Gerstmann-Straussle

132 N-terminal helix and a significant number of hydrophobic domains, important for the interaction betwe

133 group undergoes a slow interaction with the hydrophobic domain in close proximity to the active site

134 e oxide layer was present compared to a thin hydrophobic domain in contact with Pt.

135 Thus, some portion of the N-terminal hydrophobic domain in region 1 plus a second domain in r

136 -Delta196, which retained all or part of the hydrophobic domain in region 1, were recovered almost en

137 re of N terminus epitopes, and exposure of a hydrophobic domain in the C terminus.

138 x membrane-spanning segments and a conserved hydrophobic domain in the C-terminal cytosolic tail.

139 GTP/ATP-binding site in the N-terminus and a hydrophobic domain in the extreme C-terminus.

140 It follows that the hydrophobic domain in the signal for GPI modification mu

141 importance of the N-terminal and the central hydrophobic domain in these interactions.

142 mammalian cells revealed that the N-terminal hydrophobic domain in YlfA was able to localize the prot

143 A loss in surface hydrophobic domains in CK and GAPDH was again observed a

144 acid (BisANS), to monitor changes in surface hydrophobic domains in either purified rhodanese or skel

145 These results suggest that the hydrophobic domains in regions 1 and 2 contain structura

146 hsp72 interaction with two highly conserved hydrophobic domains in the nucleocapsid protein (N) C te

147 he sequence of the poliovirus polypeptide 3A hydrophobic domain, in the context of the subgenomic HCV

148 located just 3' to the sequence encoding the hydrophobic domain, indicating that the p100 form of GAP

149 GTRAP3-18 uses hydrophobic domain interactions in the ER membrane to se

150 was designed to test the hypothesis that the hydrophobic domain interacts with the lipid bilayer of t

151 A carboxyl-terminal hydrophobic domain is an essential component of the proc

152 Further, the hydrophobic domain is characterized by a hydrophobicity

153 nsient complementation assay: the C-terminal hydrophobic domain is essential for protein stability, a

154 We found that the hydrophobic domain is inserted into membranes and that t

155 hinery for GPI modification to recognize the hydrophobic domain is not due to the intrinsic nature of

156 attern resembling the ER if the NH2-terminal hydrophobic domain is present, but they are uniformly di

157 aled that a four-leucine motif (LLLL) in the hydrophobic domain is responsible for the solubility pro

158 sisting of a positively charged region and a hydrophobic domain, is essential for lipid-induced rPrP

159 uence motif in LHCP (L18) that, along with a hydrophobic domain, is required for transit complex form

160 Although Vam7p has no hydrophobic domains, it is tightly associated with the v

161 he extended, rod-like domain IV and a small, hydrophobic domain IV interface compatible with flexibil

162 by a spin label attached to Cys16 in the H2 hydrophobic domain; (iv) near-UV circular dichroism spec

163 polysaccharides (LPS) typically consist of a hydrophobic domain known as lipid A (or endotoxin), a no

164 The metal complex binds irreversibly to the hydrophobic domains leaving the pH-sensing COOHs project

165 and the inclusion of cis-unsaturation in the hydrophobic domain led to greater lipid hydration, indic

166 tions blocked LD targeting, independently of hydrophobic domain length, but dependent on their positi

167 increasing hydrophilic fraction for a fixed hydrophobic domain length.

168 llow structural variations on the linker and hydrophobic domain levels.

169 The hydrophobic domain-localized 129 polymorphism altered th

170 th a characteristic heme-binding motif and a hydrophobic domain located at the N-terminal end that is

171 tein-insensitive) and GIRK1 and contains the hydrophobic domains (M1-pore-loop-M2) of GIRK1 (G1(M)) w

172 of those sites are transmitted to the second hydrophobic domain (M2) of the subunits to induce closur

173 Thus, the hydrophobic domain may anchor the replication complex to

174 Thus, the hydrophobic domain may play an important role in Tat pro

175 patial distribution of positively charged or hydrophobic domains may provide an explanation for the d

176 al constituents transferred to the separated hydrophobic domain, mimicking bacterial cell membranes,

177 se (Mo) wild-type sequence of the N-terminal hydrophobic domain, Mo89-143WT; and (iv) the same mouse

178 perfamily member, or proteolipid proteins, 4-hydrophobic domain-motif proteins biogenetically unrelat

179 t protein to its C terminus nor deleting the hydrophobic domain near its C terminus facilitates secre

180 n isoleucine residue from a highly conserved hydrophobic domain near the middle of L32.

181 an unusual mechanism, requiring two adjacent hydrophobic domains near its carboxyl terminus.

182 hese proteins are characterized by a bilobed hydrophobic domain of 40 amino acids.

183 as the hydrophobic core of a protein or the hydrophobic domain of a lipid bilayer, may be contingent

184 Here we show that information encoded in the hydrophobic domain of a signal sequence influences the t

185 e first cytoplasmic loop near the N-terminal hydrophobic domain of ACA.

186 The chaplins share a hydrophobic domain of approximately 40 residues (the "ch

187 h selectively labels proteins exposed to the hydrophobic domain of bilayers reacted with these annexi

188 r protein, CcdA, which resembles the central hydrophobic domain of DsbD.

189 Da) shares 47% identity with the N-terminal, hydrophobic domain of E. coli IINag, but is unique among

190 investigated the contribution of the second hydrophobic domain of each of the homologous subunits al

191 NMR experiments showed that the hydrophobic domain of each peptide has a tilt angle of 1

192 sented here, however, reveal that the single hydrophobic domain of gO functions as a cleavable signal

193 ((71)VTGVTAVAQKTV(82)) in the middle of the hydrophobic domain of human alpha-synuclein is necessary

194 Our results indicated that the hydrophobic domain of IBV E alters the host secretory pa

195 The phenotype of IBV-EG3 suggested that the hydrophobic domain of IBV E may be important for the for

196 We selected the 22-amino-acid-long hydrophobic domain of poliovirus polypeptide 3A that is

197 the nucleotide binding site (NBS) and a weak hydrophobic domain of RPS2 and N, were used to amplify h

198 ncA, IncB or IncC, but each contains a large hydrophobic domain of similar size and character as in I

199 443 aa) encoded by Mtb cya contains a single hydrophobic domain of six transmembrane helices (152 aa)

200 ense mutation removing the carboxyl-terminal hydrophobic domain of SMF1 was found to mimic a smf1 gen

201 vity of water molecules through the strongly hydrophobic domain of soils and sediments.

202 ation of a mutation affecting the N-terminal hydrophobic domain of SpoIIIE that interferes with targe

203 tamate residue of GIRK2 (E315), located on a hydrophobic domain of the C terminus, is crucial for the

204 mino acid residues) was substituted with the hydrophobic domain of the GPI signal (13 amino acids), i

205 The hydrophobic domain of the GPI signal in the human folate

206 We previously reported that the hydrophobic domain of the IBV E protein, a putative viro

207 cA sequence that modifies the characteristic hydrophobic domain of the IncA protein.

208 When the entire hydrophobic domain of the leader peptide of FR-beta (12

209 an alpha-helix, which is likely to span the hydrophobic domain of the lipid bilayer to anchor the la

210 C) reaction between azide handles inside the hydrophobic domain of the membrane and an excess of a bi

211 The central hydrophobic domain of the membrane protein DsbD catalyze

212 nylalanine-to-histidine change (F69H) in the hydrophobic domain of the membrane-associated viral prot

213 We investigated the importance of the hydrophobic domain of the mouse hepatitis coronavirus (M

214 These mutations are within the second hydrophobic domain of the transporters and show the esse

215 ith Tim23p, raising the possibility that the hydrophobic domain of Tim23p does not interact with othe

216 ion of Tim23p, and tim23C, encoding only the hydrophobic domain of Tim23p.

217 hthalenesulfonate (ANS) revealed exposure of hydrophobic domains of BoNT/A LC at low pH.

218 simply modified with imaging agents, and the hydrophobic domains of hGC are available for encapsulati

219 xture of proteins for alterations in surface hydrophobic domains of individual proteins.

220 aotropic activity, by proxy, from within the hydrophobic domains of macromolecular systems (log P > 1

221 ted among functionally important residues in hydrophobic domains of membrane transport proteins, and

222 re of thermal relaxation events occurring in hydrophobic domains of Nafion.

223 A short hydrophilic Nogo-66 loop between two hydrophobic domains of Nogo binds to a Nogo-66 receptor

224 Our data indicate that both hydrophobic domains of NS3 span the cell membrane and th

225 of substrate proteins with membranes or the hydrophobic domains of other partner peptides.

226 argeting signals (mPTSs), interacts with the hydrophobic domains of PMP targeting signals, and is ess

227 arged amino acid sequence connecting the two hydrophobic domains of REEP4.

228 on principles may govern interactions of the hydrophobic domains of the GPI signal and the leader pep

229 ate the degree to which the surface and bulk hydrophobic domains of the lenses can be imaged and to i

230 Comparison of the hydrophobic domains of the localized proteins showed tha

231 In aqueous solutions, the hydrophobic domains of these species associate to produc

232 constructs found that both of the N-terminal hydrophobic domains of vp13 are needed for the interacti

233 y region 2 (aa 301-500) containing a smaller hydrophobic domain (of approximately 50 aa).

234 s, the effect of mutations in the linker and hydrophobic domains on subcellular localization in COS1

235 rophobic domain, and one bound to either the hydrophobic domain or the functionally unidentified regi

236 In addition, the MAb recognizing either the hydrophobic domain or the unidentified region adjacent t

237 S. aureus MGT contained an N-terminal hydrophobic domain perhaps involved with membrane associ

238 Bcl-2 and Bcl-xl, with the carboxyl-terminal hydrophobic domain removed, form cation-selective channe

239 The N-terminal half of ETR1 contains a hydrophobic domain responsible for ethylene binding and

240 The amino-terminal half of ETR1 contains a hydrophobic domain responsible for ethylene binding and

241 abundant in natural biofilms and possessing hydrophobic domains, retain these metabolites.

242 minimal toxicity, because unmasking of their hydrophobic domains selectively occurs in the acidic env

243 of the N-terminal half of DhkA predicts two hydrophobic domains separated by a 310-amino-acid loop t

244 ey 293 cells, indicating that the N-terminal hydrophobic domain serves as a transmembrane anchor, and

245 recent report that removal of the C-terminal hydrophobic domain significantly improved the solubility

246 me encodes a putative protein that has seven hydrophobic domains similar to those of seven membrane-s

247 t the NH2 and COOH termini are cytosolic and hydrophobic domains span the membrane in a manner consis

248 data support a model in which the N-terminal hydrophobic domain spans the membrane in a Nout-Cin orie

249 the presence of a characteristic N-terminal hydrophobic domain strongly suggested that the other pox

250 rich domain predicted to be extracellular, a hydrophobic domain suggested to be transmembranous, and

251 dues located on the carboxy side of the long hydrophobic domain, suggesting functional significance.

252 CL-20 contains four hydrophobic domains, suggesting that it is an integral m

253 ut not a mutant lacking the carboxy-terminal hydrophobic domain, targeted CED-4 from the cytosol to i

254 We show that the C-terminal hydrophobic domain targets intact TIG3 to the plasma mem

255 repeats of 78 amino acids, and a C-terminal hydrophobic domain that encodes a putative membrane anch

256 lly associate with membranes and an internal hydrophobic domain that is essential for altering membra

257 anchored (TA) proteins, bearing a C-terminal hydrophobic domain that is essential for their membrane

258 ranes and liposomes and contains an internal hydrophobic domain that is required for membrane permeab

259 s a unique N-terminal region that includes a hydrophobic domain that may function as a secretion sign

260 These experiments identify a hydrophobic domain that mediates ORF61 self-interaction.

261 erfamily, most of which contain a C-terminal hydrophobic domain that plays a role in membrane targeti

262 the intoxication process: (i) it contains a hydrophobic domain that triggers the ERAD mechanism and

263 conformational changes to expose structured hydrophobic domains that are likely responsible for subs

264 ibed synthetic lipid headgroups, linkers and hydrophobic domains that can provide control over the in

265 the presence of unprocessed or non-inserted hydrophobic domains that distinguish MLPs from potential

266 principal domains; the catalytic domain, the hydrophobic domain, the glycine/aspartate-rich repeat do

267 The judicious placing of charged groups near hydrophobic domains thus provides a strategy for tuning

268 hydrophilic segment and a carboxyl-terminal hydrophobic domain (Tim23Cp).

269 SUR contains three hydrophobic domains, TM(0), TM(1), and TM(2), with nucle

270 sible light, while the availability of these hydrophobic domains to the probe decrease under UV light

271 The VP5* protein contains a single long hydrophobic domain (VP5*-HD, residues 385 to 404) at an

272 throughout the cytoplasm when the C-proximal hydrophobic domain was deleted.

273 In addition, the sequence encoding the hydrophobic domain was found to be contained within a si

274 posttranslationally and that the C-terminal hydrophobic domain was necessary and sufficient for this

275 Furthermore, a conserved proline within the hydrophobic domain was required for membrane perforation

276 region of PLpro that includes the downstream hydrophobic domain was required for processing at the pr

277 solution (MPS), OPTI-FREE RepleniSH, on lens hydrophobic domains was also investigated.

278 sembly and of Ala-->Val substitutions in the hydrophobic domain were characterized.

279 EGFP fusion proteins with a hydrophobic domain were N and O glycosylated.

280 The amino acids at various positions in the hydrophobic domain were systematically altered and the e

281 Hydrophobic domains were determined using a saturated so

282 erminal 76 amino acids of M1 (containing two hydrophobic domains) were intact.

283 H3A-Delta397 and H3A-Delta457, lacking both hydrophobic domains, were predominantly cytosolic.

284 1 has a 58-amino acid insertion after the S8 hydrophobic domain, whereas rbslo2 is truncated and cann

285 enesis of residue 394 (W-->R) within the VP5 hydrophobic domain, which abolishes VP5-directed permeab

286 embranes via a C-terminal 20-amino-acid-long hydrophobic domain, which is flanked on each side by a h

287 found in described tryptases is a C-terminal hydrophobic domain, which may be a membrane anchor.

288 protein-coupled receptors (GPCRs) have seven hydrophobic domains, which are thought to span the lipid

289 segments, the organization of the C-terminal hydrophobic domains, which have been implicated in both

290 for extraction, as the enzyme still contains hydrophobic domains, which may interact.

291 mine whether a complete exchange of the NS5B hydrophobic domain with a domain totally unrelated to NS

292 (amino acids 1-300), which contains a large hydrophobic domain with six predicted transmembrane heli

293 region 1 (aa 1-300), which contains a large hydrophobic domain with six predicted transmembrane heli

294 ther partial or full replacement of the NS5B hydrophobic domain with the anchor sequences of poliovir

295 The deletion of the third hydrophobic domain with the carboxyl terminus abolishes

296 charged residues on the lumenal side of the hydrophobic domain, with most of the polypeptide project

297 re of a gradual melting of the heterogeneous hydrophobic domain, with part of the chains spanning inc

298 id requires interaction with a 12-amino-acid hydrophobic domain within capsid scaffold proteins.

299 in the vitelline membrane network, much like hydrophobic domains within elastin drive the assembly an

300 es contain conserved amino acid residues and hydrophobic domains within the putative Ag binding pocke