ライフサイエンスコーパス: hydrophobic region

1 scores and increased penalties for indels in hydrophobic regions).

2 HD phosphohydrolase domain and an N-terminal hydrophobic region.

3 our substitutions outside the amino-terminal hydrophobic region.

4 ins two anion binding pockets separated by a hydrophobic region.

5 nase-HPr interaction occurs mainly through a hydrophobic region.

6 localization sequence, and a single strongly hydrophobic region.

7 and, therefore, is able to dissolve the core hydrophobic region.

8 widespread aqueous access to this generally hydrophobic region.

9 proteins, revealing the presence of unfolded hydrophobic regions.

10 Inhibitors also accessed two hydrophobic regions.

11 of the protein interspersed among the larger hydrophobic regions.

12 that contains a signal sequence and several hydrophobic regions.

13 h two hydrogen bond acceptor groups and four hydrophobic regions.

14 ntermolecular interactions among the central hydrophobic regions.

15 uble nanocages (macrocations) have separated hydrophobic regions.

16 rophilic regions relative to the surrounding hydrophobic regions.

17 hat upon interaction with lipid, the central hydrophobic region (109-132) of the protein is protected

18 Khodorov's pharmacophore, which contains two hydrophobic regions, a third hydrophobic region may enha

19 oxidase, a water molecule is observed in the hydrophobic region above the top of the D path, strategi

20 hydrophobic methylthio group inserts into a hydrophobic region adjacent to the more hydrophilic 5'-h

21 This study analysed the role of the SP, the hydrophobic region after the SP (HRASP), glycosylation a

22 ctors through direct interactions with short hydrophobic regions along its structurally disordered ax

23 binds tightly to IpaB, but the IpaC central hydrophobic region also appears to participate in this b

24 Deletion of a predicted hydrophobic region (amino acids 360 to 379) in a potenti

25 It contains a highly conserved hydrophobic region (amino acids 524 to 539) located 24 a

26 rminus of SasN appears to contain a strongly hydrophobic region and a leucine zipper motif.

27 c of negative curvature lipids, with a bulky hydrophobic region and a relatively small hydrophilic he

28 to 42,000 s(-1) in the tightly bound central hydrophobic region and approximately 300 s(-1) in the di

29 This motif is followed by a hydrophobic region and charged C terminus, which are tho

30 of a protein with a QVPTGV motif preceding a hydrophobic region and charged tail.

31 r sphaeroides (RsLPS) has a relatively small hydrophobic region and does not stimulate cells or anima

32 r interactions due to their proximity to the hydrophobic region and exclusion from bulk solvent.

33 acid substitutions within an amino-terminal hydrophobic region and four substitutions outside the am

34 PyMT region containing the membrane-binding hydrophobic region and result is mislocalization of the

35 ntaneously filling the microchannels up to a hydrophobic region and splitting a liquid drop by inject

36 7 (UDPGTh2) isozyme, has a similar conserved hydrophobic region and that the positive factor for its

37 cytosol, indicating that both the C-terminal hydrophobic region and the BH3 domain are required for t

38 hat HIV-1 Tat interacts with both the acidic/hydrophobic region and the BRCT domain of FCP1, whereas

39 respectively, followed by membrane-spanning hydrophobic regions and cytoplasmic carboxyl terminal re

40 The key features such as average shape, hydrophobic regions and electrostatic patterns of active

41 ehavior; that is, FRET decreases between the hydrophobic regions and FRET increases for the N- and C-

42 Both of the repressor domains contained hydrophobic regions and had an LXVXL motif in common.

43 cDNA predicts a 25-kDa polypeptide with four hydrophobic regions and several potential phosphorylatio

44 for potential membrane-penetrating segments (hydrophobic regions) and for lipid-binding sites with hi

45 ) was substituted at the N terminus, central hydrophobic region, and C terminus of all alpha-Syns.

46 mino acid residues (15 kDa), with two highly hydrophobic regions, and resides in the inner membrane o

47 advancing contact angle of the liquid on the hydrophobic regions, and the channel depth.

48 arity to HMG1, the location of the basic and hydrophobic regions, and the site size of the fork arms

49 ind to mitochondria through their N-terminal hydrophobic regions, and their overexpression in tissue

50 and a stromal targeting domain containing a hydrophobic region approximately 60 amino acids from the

51 region and part of the carboxy (C)-terminal hydrophobic region are in direct contact with the protof

52 Narrow hydrophobic regions are a common feature of biological c

53 domains, changes to the organization of the hydrophobic regions are also observed.

54 The hydrophobic regions are fabricated by using a patterned

55 and mutational analysis, we identify a small hydrophobic region as responsible for this oligomerizati

56 Exposure of hydrophobic regions as a consequence of decreased therma

57 consistent with previous models implicating hydrophobic regions as determinants of Abeta42 aggregati

58 ervative missense mutations within a central hydrophobic region, as well as truncations and frameshif

59 9S variant of PHF8 that modifies a conserved hydrophobic region; assays with both peptides and intact

60 t Hid is localized to the mitochondria via a hydrophobic region at its C terminus and functionally in

61 enterotoxins LTI and LTIIb have a conserved hydrophobic region at the AB(5) interface postulated to

62 single potential N-glycosylation site, and a hydrophobic region at the C terminus, a finding consiste

63 ied two regions, one at the N-terminus and a hydrophobic region at the C-terminus, that jointly contr

64 Here we demonstrate that the short hydrophobic region at the distal end of the D-site plays

65 The gp36 has two long hydrophobic regions at its amino and carboxy termini, th

66 tant region of interaction between conserved hydrophobic regions at the base of TMD5 and TMD6 that is

67 ical/concave shape, the cross-section of the hydrophobic region being larger than that of the hydroph

68 pontaneously and repeatedly to span the 15-A hydrophobic region between the two known H(+) transport

69 Herein, we show that mutation of the hydrophobic region but not the sorting motifs affected t

70 unmodified lipopolysaccharides reaching the hydrophobic region, but was prevented from this penetrat

71 Introduction of negative charges into this hydrophobic region by site-directed mutagenesis disrupte

72 nsient but frequent hydration of the central hydrophobic region by water molecules from the intracell

73 thesized that their unusually long conserved hydrophobic regions cause reticulons to assume a wedge-l

74 and hydroxylated proline enclose a localized hydrophobic region centered on the brominated tryptophan

75 The results indicate that a hydrophobic region, comprising residues 214-227, forms a

76 Mutagenesis of this hydrophobic region consisting of Leu(213), Ile(293), Leu

77 nteracts solely with a portion of the acidic/hydrophobic region containing a conserved LXXLL-like mot

78 ulate that the wild-type VacA amino-terminal hydrophobic region contributes to oligomerization of the

79 On the other hand, mutants with the second hydrophobic region deleted fail to traffic to the plasma

80 90-231, T_PrP), and PrP missing its central hydrophobic region (Delta105-125, DeltaCR_PrP), were equ

81 Deletion of the central hydrophobic region eliminates IpaC's ability to interact

82 This hydrophobic region encompasses all but one of the photo-

83 Through a reaction-diffusion process, the hydrophobic region expands with a sharp transition at th

84 s and proteases, both of which can recognize hydrophobic regions exposed on unfolded polypeptides.

85 whose quantum yield increases when bound to hydrophobic regions exposed upon unfolding of the protei

86 ending from amino acids (aa) 1 to 366, and a hydrophobic region extending from aa 367 to 593.

87 DnaK's binding motif is known to comprise hydrophobic regions flanked by positively charged residu

88 from all species demonstrated two conserved hydrophobic regions flanking a surface-exposed loop.

89 the 32 N-terminal residues, which include a hydrophobic region followed by a net positive charge.

90 of the substrate binding loops, and present hydrophobic regions for potential membrane attachment.

91 transmembrane helices identify eight or nine hydrophobic regions for the SBAT sequences as membrane s

92 Ninjurin1 and 2 share conserved hydrophobic regions for their transmembrane domains; how

93 In contrast, the conserved hydrophobic region forms an extensive apolar surface at

94 However, removal of the C-terminal hydrophobic region from the M1 mutant (M1DeltaC) abolish

95 quantitative pharmacophores that identified hydrophobic regions, H-bond acceptor sites, and an ioniz

96 id sequence of Trp proteins identifies seven hydrophobic regions (H1-H7) with potential of forming tr

97 beta-sheet association around the C-terminal hydrophobic region; however, it shifts the relative popu

98 PS1 contains 10 hydrophobic regions (HRs) sufficiently long to be alpha-

99 s indicate that these proteins contain eight hydrophobic regions (HRs) that could potentially form al

100 Joint targeting of the hydrophobic region I and methylation of imidazole-N1 pos

101 This should result in targeting of the hydrophobic region I, the "deep pocket", and the hinge g

102 flip at the hinge region and occupying both hydrophobic regions I and II.

103 lowed by a further derivatization to address hydrophobic region II.

104 dies suggest that selected residues within a hydrophobic region immediately preceding the second memb

105 Trp and/or other hydrophobic residues and a hydrophobic region in alpha(2)M*.

106 overall results demonstrate that a localized hydrophobic region in CTx PnIB interacts with conserved

107 alignments, we identified a conserved acidic/hydrophobic region in FCP1 adjacent to its highly conser

108 features were the same hydrophobic slope, a hydrophobic region in residues 35-45, and, in eight of 1

109 ith spastin, and this interaction required a hydrophobic region in spastin that is involved in ER loc

110 A conserved hydrophobic region in the bilirubin-type UDP-glucuronosy

111 N-terminus and those that extended into the hydrophobic region in the C-terminal half of the transit

112 mechanism and discovered that CENP-C binds a hydrophobic region in the CENP-A tail and docks onto the

113 for a fusion peptide role for the conserved hydrophobic region in the Ebola virus GP.

114 he M28L and I37T loci are buried in a mostly hydrophobic region in the middle.

115 and several charged residues and a conserved hydrophobic region in the N-terminal portion of BovK sen

116 iddle section of the channel deep inside the hydrophobic region in the sodium dodecyl sulfate micelle

117 t the farnesyl group is sequestered within a hydrophobic region in the tail domain in the absence of

118 A small hydrophobic region in the TM ectodomain from amino acid

119 lysis by the RAOARGOS computer program, this hydrophobic region in UGT1A1 is located between residues

120 n a mixed domain network copolymer utilizing hydrophobic regions in a hydrophilic, water-swellable, p

121 both non-crystalline and crystalline ordered hydrophobic regions in all the EW membranes except the 7

122 pported by (i) the presence of two conserved hydrophobic regions in SSP (hphi1 and hphi2) and (ii) ou

123 We present a new method for the analysis of hydrophobic regions in the binding site of a protein tha

124 Thus, the hydrophobic regions in the C termini of BH3-only members

125 y showed that, likely due to the presence of hydrophobic regions in the GO basal plane, the GO membra

126 ions giving rise to the rearrangement of key hydrophobic regions in the tetramer and the formation of

127 w that cholesterol may bind to two nonanular hydrophobic regions in the transmembrane domain of Kir2.

128 A fusion protein containing a mutant VacA hydrophobic region (in which glycine 14 of VacA was repl

129 f these domains in isolation showed that the hydrophobic regions insert obliquely into the bilayer, w

130 Following the hydrophobic region is a negatively charged region that i

131 When a short hydrophobic region is added to a sequence that directly

132 This ATP-incompatible hydrophobic region is distinct from the previously chara

133 nd whether an exact alignment of the central hydrophobic region is essential.

134 he occurrence of two charged residues in the hydrophobic region is expected to destabilize the region

135 ecular dynamics simulations suggest that the hydrophobic region is helical and has a transmembrane or

136 ons, that a precise alignment of the central hydrophobic region is not essential, and that the antipa

137 In contrast, the N-terminal hydrophobic region is not required for ER membrane targe

138 f the sequence between the first AUG and the hydrophobic region is translated, we produced a specific

139 eates a new N terminus on F1 that contains a hydrophobic region, known as the FP, which intercalates

140 een before, namely, fibril formation both in hydrophobic regions L17-A21 and G37-A42 preceding fibril

141 propensity for beta-strand structure at two hydrophobic regions (Leu17-Ala21 and Ile31-Val36), and t

142 A, and G26A) were introduced into the unique hydrophobic region located near the amino terminus of Va

143 ch contains two hydrophobic regions, a third hydrophobic region may enhance binding to provide nanomo

144 GPs suggests that the conserved Ebola virus hydrophobic region may, in fact, serve as the fusion pep

145 A wild-type VacA hydrophobic region mediated insertion of the fusion prot

146 recognition sequence along with an extensive hydrophobic region near the amino terminus, suggesting t

147 This site, Ser-2481, is located in a hydrophobic region near the conserved carboxyl-terminal

148 t a pivot point formed by a highly conserved hydrophobic region near the middle of the voltage sensor

149 acid signal peptide which includes a typical hydrophobic region near the N-terminus (VLVLVL).

150 It was determined that a hydrophobic region near the N-terminus of the YlfA prote

151 yze the functional role of a unique strongly hydrophobic region near the VacA amino terminus, we cons

152 acA Delta 6-27) that lacks a unique strongly hydrophobic region near the VacA NH(2) terminus.

153 g of the charged surface patches relative to hydrophobic regions near the C terminus of the protein o

154 proliferation requires an intact N-terminal hydrophobic region necessary for the formation of anion-

155 on data indicate the presence of a collapsed hydrophobic region next to the hairpin that includes app

156 Thus, a large, nondiscriminating hydrophobic region occurs in the A3 receptor in proximit

157 tostability, and localization in the central hydrophobic region of a bilayer all make this pair of pr

158 ociation depend on their location within the hydrophobic region of a transmembrane helix.

159 clonal antibody 4G8, which targets a central hydrophobic region of Abeta.

160 se results are consistent with burial of the hydrophobic region of alpha-helical LL-37 in oligomeric

161 binds distally to the active site, burying a hydrophobic region of BSSalpha, whereas BSSbeta binds to

162 cent descriptions of the architecture of the hydrophobic region of complex I have resolved one vital

163 tion is attributed to the interaction of the hydrophobic region of E(#) with the hydrophobic patches

164 itric oxide (NO) reaction with O2 within the hydrophobic region of either phospholipid or biological

165 istribution pattern, the putative N-terminal hydrophobic region of FAAH-2 was identified as a functio

166 n selects the best-fitting hydrazone for the hydrophobic region of its active site.

167 K7-interacting protein and that the central hydrophobic region of K7 and the carboxy-terminal UBA do

168 ic side-chain of Phe209 to interact with the hydrophobic region of Rho adjacent to its GTP-binding si

169 used to measure electrostatic fields in the hydrophobic region of the active site of human aldose re

170 The middle hydrophobic region of the alpha-synuclein protein, also

171 m new core structures that interact with the hydrophobic region of the AR ligand-binding domain.

172 pids demonstrate that LL-37 inserts into the hydrophobic region of the bilayer and alters the chain p

173 The penetration of the peptide into the hydrophobic region of the bilayer is reflected in a mark

174 e nonpolar fluorophores are localized in the hydrophobic region of the bilayer thus producing minimal

175 e requires insertion of the peptide into the hydrophobic region of the bilayer, the other is much mor

176 , HZ is located nearly completely within the hydrophobic region of the bilayer.

177 ne reveal insertion of DnaA protein into the hydrophobic region of the bilayer; this insertion is acc

178 The hydrophobic region of the catalytic-site pocket was expl

179 Instead, a hydrophobic region of the FADD death-effector domain tha

180 l analysis to address the role of a specific hydrophobic region of the GIRK1 subunit.

181 10-136, a peptide encompassing the conserved hydrophobic region of the human prion protein, has been

182 icative of partial insertion of PR3 into the hydrophobic region of the lipid membranes.

183 ses the degree of water penetration into the hydrophobic region of the membrane) more than does (LA)(

184 s indicates that cPLA2C2 penetrates into the hydrophobic region of the membrane.

185 These spectral changes suggest that the hydrophobic region of the micelle surrounding SWNTs swel

186 d subphase and the other end embedded in the hydrophobic region of the monolayer.

187 t the upstream level, baicalein bound to the hydrophobic region of the myeloid differentiation protei

188 h has a good match between the length of the hydrophobic region of the peptide and the bilayer length

189 that the conserved cysteine is located in a hydrophobic region of the permease.

190 e sodium versus chloride ions in the central hydrophobic region of the pore.

191 The lipids are located in the hydrophobic region of the protein surface and interact p

192 phaII to alphaI leads to the exposure of the hydrophobic region of the protein to the aqueous medium.

193 During fusion a hydrophobic region of the protein, termed the fusion pep

194 ain with the burial of the methyl group in a hydrophobic region of the protein.

195 actions were formed mainly by the N-terminal hydrophobic region of the protein.

196 cleavage site localized to the middle of the hydrophobic region of the signal peptide.

197 Thus, the hydrophobic region of the third alpha-helix of Vpr is cr

198 This hydrophobic region of the toxin probably inserts into th

199 Mutation of residues on the hydrophobic region of this helix abolishes the ability t

200 Thus, the first hydrophobic region of Trp rather than being a transmembr

201 (14)XXXG(18) motif within the amino-terminal hydrophobic region of VacA are essential for membrane ch

202 Within a unique amino-terminal hydrophobic region of VacA, there are three tandem GXXXG

203 Interactions between the hydrophobic regions of a binding site and those of a com

204 (21-30) had a high binding propensity to the hydrophobic regions of Abeta(1-42), but only CTFs were f

205 Several conserved histidine residues in hydrophobic regions of CP47 have been shown to be import

206 ar protein homeostasis by binding to exposed hydrophobic regions of incompletely folded or aggregated

207 is based on shape complementarity, matching hydrophobic regions of inhibitor and enzyme, and interac

208 haperone binding protein (BiP) binds exposed hydrophobic regions of misfolded proteins.

209 Deletion of hydrophobic regions of NS2B, leaving only the conserved

210 his membrane requirement was dictated by the hydrophobic regions of NS2B.

211 (CpG motifs for TLR-9 stimulation) into the hydrophobic regions of Pluronic F127 micelles, followed

212 egment, indicating that both hydrophilic and hydrophobic regions of RyR1 are necessary for 4-CmC bind

213 iments that support the view that two of the hydrophobic regions of SEL-12 function as the seventh an

214 interactions between the peptide and deeper hydrophobic regions of the membrane provide energy to pe

215 stive of the peptide being squeezed out from hydrophobic regions of the monolayer.

216 ipid mixture is the packing mismatch between hydrophobic regions of the monopolar lipid hydrocarbon c

217 ns to interact optimally with conjugated and hydrophobic regions of the neonicotinoid.

218 s in protein solubilization by shielding the hydrophobic regions of the newly extracted protein from

219 cetyloxy and benzyl ring of TAB probes large hydrophobic regions of the p-aminobenzoyl folate binding

220 one initially interacts nonspecifically with hydrophobic regions of the partially denatured HBD and s

221 Dehydration of hydrophobic regions of the protein surface as they enter

222 on effector, we find that the N terminal and hydrophobic regions of the signal sequence affect integr

223 g of longer chain alkyl sulfates by specific hydrophobic regions of these otherwise similar proteins.

224 These molecules recognise exposed hydrophobic regions of unfolded or denatured proteins.

225 drolysis to regulate their interactions with hydrophobic regions of unfolded proteins.

226 further FRET increases occur between the two hydrophobic regions of VHL, accompanied by FRET decrease

227 no-8-naphthalenesulfonate demonstrate that a hydrophobic region on L5 becomes exposed upon removal of

228 Clear evidence for matching of hydrophobic regions on rhodopsin transmembrane helices a

229 s alone, organic liquids are confined to the hydrophobic region only if the aqueous liquid first occu

230 ort vesicles by the stromal targeting domain hydrophobic region oriented with the presequence N termi

231 It has been assumed that the hydrophobic region penetrates the hydrophobic lipid bila

232 entaacetic acid indicated that the conserved hydrophobic region peptide is not inserted symmetrically

233 ults in burying the 2(')-hydroxyl group in a hydrophobic region (Phe62) of POT1 in addition to elimin

234 a large hydrophobic residue), which is in a hydrophobic region predicted to be a membrane reentrant

235 These studies reveal that changes in the hydrophobic region predicted to be nearest to FeA can in

236 Our results show that four hydrophobic regions predicted as the potential transmemb

237 that "bridges" of several water molecules in hydrophobic regions present a problem (rather than a sol

238 SDS is able to prevent the exposure of large hydrophobic regions present in membrane proteins which o

239 H also confirms that its localization in the hydrophobic region prevents lipid peroxidation.

240 Each has a single hydrophobic region probably folded into a membrane spann

241 The dynamics of the hydrophobic regions probed at Leu-17, Leu-34, Val-36, an

242 The computed PMF indicates that the central hydrophobic region provides the major hindrance for ion

243 Short hydrophobic regions referred to as fusion peptide domain

244 conclude that peptides with both charged and hydrophobic regions require combined strategies to preve

245 ansgenic mice identified an eight-amino-acid hydrophobic region required for secretion and incorporat

246 These peptides bound to the hydrophobic region (residues 17-21) or to the nearby pro

247 mational change that lead to the exposure of hydrophobic regions responsible for target protein recog

248 ile all other free Cs are located within the hydrophobic region(s) of the enzyme.

249 to interact with the 1-hydroxyl as well as a hydrophobic region(s) to interact with chemical groups a

250 erminus, MaxiK channels have four additional hydrophobic regions (S7-S10) of unknown topology.

251 residue SSP comprises two membrane-spanning hydrophobic regions separated by a short ectodomain loop

252 nd maturation, while the extended C-terminal hydrophobic region serves as a stable membrane anchor fo

253 We demonstrate that the resulting hydrophobic-region signal-peptide substitution (p.Thr17A

254 A long hydrophobic region spanning amino acids 66-115 likely co

255 unit (Met1 to Lys100) and suggested that the hydrophobic region spanning Lys100 to Pro141 defines a d

256 The hydrophobic region, spanning residues I224 through N241

257 We have harnessed the signal sequence hydrophobic region (SSHR) to deliver functional cargoes

258 ed in a transformant deleted for part of the hydrophobic region, suggesting that this protein is defe

259 e for a smaller nonpolar residue in the pore hydrophobic region suggests an important role for the la

260 onfirms that the active site is located in a hydrophobic region surrounding Pro-1.

261 t point mutations outside the amino-terminal hydrophobic region that are known to abrogate vacuolatin

262 a series of site-specific mutations in this hydrophobic region that disrupt transmembrane propensity

263 ted to form an oligomeric interaction with a hydrophobic region that includes the site of a previousl

264 The surface of the trimer has a hydrophobic region that is modeled as the complex being

265 with T105I, reflective of substitution in a hydrophobic region that opposes the active site.

266 , containing an integrin binding motif and a hydrophobic region that permeabilizes membranes and is h

267 ve residues within the amino terminus of the hydrophobic region that play a critical role in invasion

268 in their catalytic center and in an internal hydrophobic region that shows strong transmembrane prope

269 ay be due to the lack in beta-synuclein of a hydrophobic region that spans residues 73-83 of alpha-sy

270 om temperature, suggesting that there are no hydrophobic regions that are protected from the aqueous

271 All presenilins have multiple hydrophobic regions that could theoretically span a memb

272 a contain spatially distinct hydrophilic and hydrophobic regions that impose a high degree of structu

273 smembrane domains, with two highly conserved hydrophobic regions that might associate with or penetra

274 ture is very similar within the loops of the hydrophobic region, the presence of two unique residues

275 ain, a large C-terminal segment, and several hydrophobic regions thought to multiply span the subrhab

276 nt mutants showed that borrelidin binds to a hydrophobic region (Thr-307, His-309, Cys-334, Pro-335,

277 te that, rather than being merely additional hydrophobic regions to promote insertion, the signal pep

278 how that during activation the extracellular hydrophobic region undergoes major changes involving an

279 strate binding domain and the alpha-Syn core hydrophobic region underlie assembly inhibition.

280 h one in type I cadherins, and include large hydrophobic regions unique to type II interfaces.

281 molecular docking to identify the additional hydrophobic region uniquely conserved in flavivirus MTas

282 drophobic perturbations in the middle of the hydrophobic region, we have individually replaced the al

283 de chain chemistry and length of the helical hydrophobic region, we synthesized, purified, and perfor

284 sensitivity is primarily due to the exposed hydrophobic regions, we mutated residue beta Gly86 at th

285 reas short fragments with only a cationic or hydrophobic region were cell-permeant without the attend

286 d that two hydrogen bond acceptors and three hydrophobic regions were common features.

287 c islands, as small as 500 nm, surrounded by hydrophobic regions were prepared using lithography and

288 In BenM, benzoate also bound in an adjacent hydrophobic region where it alters the effect of muconat

289 known to interact with phospholipids and has hydrophobic regions which could bind to the hydrophobic

290 indicated conservation of N- and C-terminal hydrophobic regions which have the hallmarks of secretor

291 Sequence analysis revealed two hydrophobic regions which may result in the formation of

292 he shape of the molecules, especially in the hydrophobic region, which induces dramatic transformatio

293 hat formed van der Waals interactions with a hydrophobic region within the AMP binding site and by re

294 t NY-1V G1 tail degradation are present in a hydrophobic region within the C-terminal 30 residues of

295 of the interaction of these agents with the hydrophobic region within the C1 domains was investigate

296 This analysis targeted a hydrophobic region within the L1-binding domain of L2 as

297 We have noted a hydrophobic region within the primary amino acid sequenc

298 tromal targeting domain, indicating that the hydrophobic region within this domain functions as a sto

299 Two hydrophobic regions within the core were highly resistan

300 hosphate-binding pocket and several distinct hydrophobic regions within VHR's active site.