ライフサイエンスコーパス: hydroxide ion

1 the nature of the nucleophile (water versus hydroxide ion).

2 l cluster or the nucleophilic metal-bridging hydroxide ion.

3 action with a tetraaquo magnesium (II)-bound hydroxide ion.

4 le to regenerate the nucleophilic zinc-bound hydroxide ion.

5 two metals and thus displacing the bridging hydroxide ion.

6 zero order, first order, and second order in hydroxide ion.

7 robes, AE was readily hydrolyzed by water or hydroxide ion.

8 multaneously deprotonated by an Mg(2+)-bound hydroxide ion.

9 concentrations of denaturant, reductant, and hydroxide ion.

10 ecomposed in the presence of ethanethiol and hydroxide ion.

11 3'-terminus is transferred to the resulting hydroxide ion.

12 ntly shared between a water molecule and the hydroxide ion.

13 c amide, regenerating SP after eliminating a hydroxide ion.

14 ter, originally occupied by the nucleophilic hydroxide ion.

15 nt metal ions bridged by a water molecule or hydroxide ion.

16 s is a reversible second-order reaction with hydroxide ion.

17 s 162) and a solvent molecule, most likely a hydroxide ion.

18 hieved simply by electrokinetic injection of hydroxide ions.

19 rbed monomer dissociates and forms a pair of hydroxide ions.

20 What is the solvation structure of the hydroxide ion?

21 e media; their degradation is induced by the hydroxide ion, a potent nucleophile.

22 ange in mechanism brought about by attack of hydroxide ion acting as a base to deprotonate a carbocat

23 An alternative mechanism in which the hydroxide ion acts as a general base is considered unlik

24 hydronium ion is produced, the corresponding hydroxide ion adds to MV(2+) to form a covalently bound

25 We propose a conceptual model describing hydroxide ion adsorption behavior in silica gel and its

26 in the spectra are observed at n = 4 in the hydroxide ion and at n = 5 in the fluoride ion.

27 he SN2 reactions between methyl chloride and hydroxide ion and between 1,2-dichloroethane and acetate

28 2+, releasing the coordinate to the bridging hydroxide ion and increasing its nucleophilicity.

29 en = F, Cl, Br, and I) with the nucleophiles hydroxide ion and pyridine have been investigated quanti

30 d waters respectively generate the attacking hydroxide ion and the proton for donation to the leaving

31 Barium, sodium, and hydroxide ions and water molecules are found in the chan

32 inity inhibitors displace the metal-bridging hydroxide ion (and sometimes occupy a Mn(2+)(A) site fou

33 re 27:1.9:1.9:1 (cyanide ion), 29:2.6:2.4:1 (hydroxide ion), and 39:3.9:3.5:1 (pyridine), respectivel

34 site; they are about 5:2:1 for cyanide ion, hydroxide ion, and pyridine for attack at the halogen-be

35 and 6.3 x 10(8) M(-1) s(-1) for cyanide ion, hydroxide ion, and pyridine, respectively.

36 es the catalytic nucleophile, metal-bridging hydroxide ion, and stabilizes the tetrahedral intermedia

37 liphatic amines, secondary alicyclic amines, hydroxide ion, and water in water at 25 degrees C and in

38 Free neutral imidazole and hydroxide ion are also effective quenchers of p-cyanophe

39 this feature is that both the hydronium and hydroxide ion are decorated with proton wires.

40 a high concentration of partially desolvated hydroxide ions around the bound guest arising from ion-p

41 arbon deprotonation of proline zwitterion by hydroxide ion at 25 degrees C.

42 hat a higher concentration of metal-bridging hydroxide ion at physiological pH for Co(2+)(2)-HAI, a c

43 fully prevent recombination of hydronium and hydroxide ions at 3-coordinate bridgehead sites.

44 h protonation and rehybidization of N-3 with hydroxide ion attack on the adjacent carbon to create a

45 ng reactions, has been found to catalyze the hydroxide ion attack on the P-N bond of selected 5'-mono

46 The enzyme operates by hydroxide ion attack, which is intrinsically associated

47 monium salt to transfer a nucleophile (e.g., hydroxide ion) between an aqueous and organic layer cont

48 In addition to the binding of hydroxide ion, both FixLN and FixL undergo additional al

49 rdination anions, the metalloporphyrins form hydroxide ion bridged dimers within the organic phases,

50 ilibrium of a indium(III) octaethylporphyrin hydroxide ion-bridged dimer species with corresponding m

51 the porphyrin species spontaneously forms a hydroxide ion-bridged dimer, with the added lipophilic b

52 ration reaction is strongly catalyzed by the hydroxide ion but shows acid catalysis only at pH < 1.

53 This method relies on in situ formation of hydroxide ions by electro mediated water reduction at a

54 In comparison with the hydroxide ion catalyzed reaction, the enhancement in k(o

55 The value of kHO for hydroxide ion-catalyzed deprotonation of the alpha-imino

56 plays a later transition state compared with hydroxide-ion-catalyzed hydrolysis of the beta-sultam.

57 ginary conductivity coincided with increased hydroxide ion concentration during urea hydrolysis.

58 (a) at the surface, and implying an enhanced hydroxide ion concentration in the surface region relati

59 embrane (AEM) and catalyst layer ionomer for hydroxide ion conduction were used without the addition

60 ss-linked membrane materials exhibiting high hydroxide ion conductivity and good mechanical propertie

61 eta), His462(N)(epsilon)(2) (162beta), and a hydroxide ion (d(Fe-OH) = 1.91 A) in a distorted bipyram

62 The Bronsted base appears to be water or hydroxide ion depending on pH.

63 .e., under conditions in which hydronium and hydroxide ions do not participate directly in the reacti

64 OH)(2)(+)], (3) directly deliver one or more hydroxide ions during formation of the latter two specie

65 charged ions that, together with protons and hydroxide ions, facilitate biochemical reactions and est

66 tions to the reduction of the free energy of hydroxide ion formation.

67 ciation to atomic oxygen but by regenerating hydroxide ions formed via the catalytic decomposition of

68 hanisms; and (d) regeneration of metal-bound hydroxide ion from a metal-bound water molecule requires

69 ytosine (C75) acts as the general acid and a hydroxide ion from the divalent metal ion, or possibly f

70 the aqueous solvent, is assigned to loss of hydroxide ion from the intermediate.

71 ing step from proton transfer to the loss of hydroxide ion from the intermediate.

72 ge of neutral alpha-carbonyl carbon acids by hydroxide ion, from -0.40 to -1.0.

73 pled with elimination of the benzylic OH (as hydroxide ion) gave zwitterions (formal m-quinone methid

74 ated as a function of both the amount of the hydroxide ions generated and the mass-transfer character

75 ing through the porous membrane, consumed by hydroxide ions generated in the cathode reaction Ag(2)O(

76 om CH3Cl, C2H5Cl, and C2H4Cl2 by acetate and hydroxide ions have been investigated, using ab initio m

77 enzimidazoles (HMT-PMBI), charge balanced by hydroxide ions (IEC from 2.1 to 2.5 mequiv/g), and comme

78 induced by nucleophilic attack of C1' with a hydroxide ion in 5-substituted 2'-deoxycytidines.

79 ate (4-SMe) with morpholine, piperidine, and hydroxide ion in 50% DMSO/50% water (v/v) at 20 degrees

80 azirine (2) was synthesized and reacted with hydroxide ion in a Fourier transform mass spectrometer t

81 Hydroxide ion in both unmodified and deproteinated bone

82 obtained clear evidence for the presence of hydroxide ion in deproteinated bone by (1)H MAS NMR.

83 r proton transfer from these carbon acids to hydroxide ion in H(2)O.

84 With benzaldehyde and zinc-bound hydroxide ion in the active site, the oxygen of Zn(II)-O

85 this formula is the application of a potent hydroxide ion in the concoction.

86 experiment provided unambiguous evidence for hydroxide ion in unmodified bone as well.

87 enzothiophene-3(2H)-one (3H-S) by amines and hydroxide ion in water at 25 degrees C is reported.

88 tro-1-(4-nitrophenyl)ethane (NNPE(H(D))) and hydroxide ion in water/acetonitrile (50/50 vol %) were s

89 e, dynamics, and transport of the proton and hydroxide ions in different aqueous environments, rangin

90 solid-state porous coordination polymer and hydroxide ions in solution.

91 low populated species such as hydronium and hydroxide ions in water.

92 p 250, and a solvent molecule (most likely a hydroxide ion) in a trigonal bipyramidal arrangement.

93 nd was notably weak and nonselective for the hydroxide ion, in accord with Hofmeister bias.

94 Hydroxide ion inhibits Photosystem II (PSII) activity by

95 monstrate that oxygen atoms originating from hydroxide ions instead of molecular oxygen are incorpora

96 a manner consistent with the partitioning of hydroxide ions into the membrane.

97 The metal-activated hydroxide ion is a critical nucleophile in metalloenzyme

98 Although loss of hydroxide ion is hugely exothermic, a concerted reaction

99 A second solvent (possibly a hydroxide ion) is bound terminally to Co2.

100 ng rate constants for nucleophilic attack by hydroxide ion (kOH), by water (kH2O), and by general bas

101 thway for degradation that is first order in hydroxide ion, liberates only one equiv of pyridine, and

102 s suggest a mechanism in which a metal-bound hydroxide ion located near the ligation junction promote

103 eaction conditions suggests that solvent and hydroxide ions may play important roles as general base

104 e been interpreted as supporting a one-metal-hydroxide-ion mechanism.

105 a pH-k(bkdn) profile consistent with solvent-hydroxide ion mediated ester hydrolysis.

106 phosphothreonyl residues were derivatized by hydroxide ion-mediated beta-elimination followed by the

107 The PhIAT labeling approach involves hydroxide ion-mediated beta-elimination of the O-phospha

108 In contrast, hydroxide ion mobility in basic solutions has received f

109 A duplexes using standard protocols, and the hydroxide ions necessary for mediating the dehybridizati

110 erved lysine, which stabilizes the attacking hydroxide ion nucleophile.

111 lfonamide group displaces the metal-bridging hydroxide ion of the native enzyme and bridges the binuc

112 arginine, simply displace the metal-bridging hydroxide ion of the native enzyme and do not cause any

113 ead to sustained slow release of calcium and hydroxide ions of CH for long periods of time, eliminati

114 r, to predict the mechanism of conversion of hydroxide ion (OH(-)) to OH(*) or H2O2 (hydrogen peroxid

115 atinum ultramicroelectrode (UME), generating hydroxide ions (OH(-)) by the oxygen reduction reaction

116 Compared to other ions, protons (H(+)) and hydroxide ions (OH(-)) exhibit anomalously high mobiliti

117 lectrons and aqueous ions yield an excess of hydroxide ions (OH(-)), making the solution more basic,

118 m electrode is used to controllably generate hydroxide ions (OH(-)), which flood the downstream detec

119 ing isoporphyrin formation through attack of hydroxide ion on a cationic iron porphyrin with an oxidi

120 intermediate, formed by attack of water or a hydroxide ion on C2(PEP).

121 f decomposition is consistent with attack by hydroxide ion on the methylguanidinium ion (k2 = 5 x 10(

122 licit a nucleophilic attack of the resulting hydroxide ion on the nearby C-2(PEP), thus triggering th

123 ase catalysis for the nucleophilic attack of hydroxide ion on the scissile phosphate, and general aci

124 anism for the synthesis of KDO8P, in which a hydroxide ion on the si side of PEP attacks C2(PEP), for

125 mote the nucleophilic attack of a zinc-bound hydroxide ion onto the ceramide amide carbonyl.

126 In addition, the structure suggested that a hydroxide ion or a water bridging two metal ions may ser

127 creased reactivity toward amines relative to hydroxide ion, probably related to the expulsion of the

128 that the anomalous diffusion of the aqueous hydroxide ion results from its ability to accept a proto

129 Both Lys 169 and a water molecule (or hydroxide ion) serve to bridge the two zinc ions togethe

130 The component of hydroxide ion serves two major functions.

131 ed to the solvent at high pH, resulting in a hydroxide ion that pulls the Znbeta2+ ion closer to form

132 tracts a proton from water and the resulting hydroxide ion then hydrolyzes AE.

133 a bridging carboxylate and a bridging water/hydroxide ion, thought to be the nucleophile that hydrol

134 es prior to the beta-elimination event or by hydroxide ion to cleave the glycosylic bond.

135 ergoes nucleophilic attack by metal-bridging hydroxide ion to yield a tetrahedral boronate anion that

136 azole in the cavity and (2) polar binding of hydroxide ions to sites on the cage surface, both of whi

137 ibly positioned to generate the nucleophilic hydroxide ion, to compensate for the incipient additiona

138 in that their hemes are not fully ligated by hydroxide ion under strongly alkaline conditions.

139 te nucleophilic attack by the metal-bridging hydroxide ion upon binding to the arginase active site.

140 In unmodified bone mineral hydroxide ion was found, through a (1)H-(31)P heteronucl

141 Catalysis by the hydroxide ion was observed for the reactions of (1)HNO w

142 loro-3-nitropyridine with two equivalents of hydroxide ion was studied by NMR and X-ray crystallograp

143 Hydroxide ions were detected uniformly throughout the ox

144 ) is electrooxidized into nitrogen consuming hydroxide ions, which is the fuel cell-relevant faradaic

145 ates aldehyde disproportionation promoted by hydroxide ions, which leads to the formation of the corr

146 e rate of the first phase is second order in hydroxide ion, while that of the second is pH-independen

147 mechanism involving nucleophilic attack by a hydroxide ion with H125 functioning as a proton donor to

148 histidine ligands (H94, H96, and H119) and a hydroxide ion with tetrahedral geometry.

149 c interaction for complex formation of metal hydroxide ion with the partially charged side of biomole

150 rapid exchange of either a terminal water or hydroxide ion with water occurs at the ferric ion in the

151 based on simultaneous binding equilibria of hydroxide ions with two metalloporphyrins to form the di

152 tion of crystal structures suggests that the hydroxide ion would react at the re-face of the flavin,