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1 us etanercept or MTX plus sulfasalazine plus hydroxychloroquine).
2 r risk was observed among patients receiving hydroxychloroquine.
3 verity and SLE are predictors of response to hydroxychloroquine.
4 ave any significant influence on response to hydroxychloroquine.
5 s (DLE) is the 4-aminoquinolone antimalarial hydroxychloroquine.
6 ficantly associated with lack of response to hydroxychloroquine.
7 study of 200 patients with DLE treated with hydroxychloroquine.
8 hip between disease activity and response to hydroxychloroquine.
9 The primary outcome was clinical response to hydroxychloroquine.
10 sive agents other than low-dose steroids and hydroxychloroquine.
11 herapy, most commonly low-dose prednisone or hydroxychloroquine.
12 .001), compared with those who had not taken hydroxychloroquine.
13 ts were nonadherent to prednisone and 51% to hydroxychloroquine.
14 -0.92) compared with those who had not taken hydroxychloroquine.
15 red suitable for identifying nonadherence to hydroxychloroquine.
16 medications were changed to methotrexate and hydroxychloroquine.
17 reated with prednisone, cyclophosphamide, or hydroxychloroquine.
18 t remained on a regimen of sulfasalazine and hydroxychloroquine.
19 alone or a combination of sulfasalazine, and hydroxychloroquine.
20 Similar results were obtained with hydroxychloroquine.
21 on of sulfasalazine (500 mg twice daily) and hydroxychloroquine (200 mg twice daily), or all three dr
22 eceive minocycline, 100 mg twice per day, or hydroxychloroquine, 200 mg twice per day, in a 2-year, d
23 ; (2) methotrexate without TNF inhibitors or hydroxychloroquine; (3) hydroxychloroquine without TNF i
24 f 35 patients treated with sulfasalazine and hydroxychloroquine (40 percent), P = 0.003 for the compa
25 Patients were randomized (1:1) to receive hydroxychloroquine (400 mg/d) or placebo until week 24.
27 pisodes; rate, 23.8; 95% CI, 23.0-24.6); and hydroxychloroquine (50 cases among 5682 treatment episod
29 though the majority of patients responded to hydroxychloroquine, a significant proportion (39%) eithe
30 xate, thiopurines, anti-TNFs, sulfasalazine, hydroxychloroquine, abatacept, or rituximab after the in
32 efit, triple therapy, with sulfasalazine and hydroxychloroquine added to methotrexate, was noninferio
33 h such a clot lasts, we investigated whether hydroxychloroquine alters the dynamics of such thrombus
34 ts with rheumatoid arthritis (1808 had taken hydroxychloroquine and 3097 had never taken hydroxychlor
35 es was reported by 54 patients who had taken hydroxychloroquine and by 171 patients who had never tak
40 between the 2 groups (-4.8% and -4.2% in the hydroxychloroquine and placebo groups, respectively, at
42 studies, there is experimental evidence that hydroxychloroquine and statins may play a role in the ma
44 ewly described potential beneficial roles of hydroxychloroquine and the statins for the treatment of
45 hydroxychloroquine and 3097 had never taken hydroxychloroquine) and no diagnosis or treatment for di
48 ologic conditions, the role of other agents (hydroxychloroquine, antioxidants), and novel immunomodul
50 hy associated with the use of chloroquine or hydroxychloroquine are not undergoing routine monitoring
54 holipid syndrome (IgG-APS) and then fed with hydroxychloroquine at various doses (100, 6, and 3 mg/kg
55 us etanercept or MTX plus sulfasalazine plus hydroxychloroquine) at week 24 if the DAS28-ESR was >/=
56 l involvement in short- and long-term use of hydroxychloroquine before the development of retinopathy
59 ts with rheumatic diseases, indomethacin and hydroxychloroquine, can directly inhibit HIV-1 replicati
60 for individuals starting a TNF inhibitor or hydroxychloroquine compared with initiation of other non
61 thotrexate, and 0.54 (95% CI, 0.36-0.80) for hydroxychloroquine compared with other nonbiologic DMARD
62 ts with primary Sjogren syndrome, the use of hydroxychloroquine compared with placebo did not improve
63 ot taking antiretroviral therapy, the use of hydroxychloroquine compared with placebo did not reduce
64 ion members among 2361 patients who had used hydroxychloroquine continuously for at least 5 years acc
66 developed retinal toxic effects after using hydroxychloroquine for a mean of 10.4 years (range, 3-19
67 nts with the pericentral pattern were taking hydroxychloroquine for a somewhat longer duration (19.5
68 ical trial testing high-dose (1000 mg daily) hydroxychloroquine for advanced non-small cell lung canc
71 use (P < .001 for trend); among those taking hydroxychloroquine for more than 4 years (n = 384), the
72 ted steroids, intravenous immunoglobulin and hydroxychloroquine for prevention and treatment of disea
73 phagy stimulator (Tunicamycin) or inhibitor (Hydroxychloroquine) functionally proved that autophagy w
74 less prednisone at 2 years compared with the hydroxychloroquine group (mean 0.81 mg/day compared with
75 ral therapy was started in 9 patients in the hydroxychloroquine group and 1 in the placebo group.
76 e primary end point was 17.9% (10/56) in the hydroxychloroquine group and 17.2% (11/64) in the placeb
77 , there were 2 serious adverse events in the hydroxychloroquine group and 3 in the placebo group; in
78 , there were 3 serious adverse events in the hydroxychloroquine group and 4 in the placebo group.
80 ients reported influenza-like illness in the hydroxychloroquine group compared with the placebo group
82 [95% CI, -1.6 to 3.3] in the clarithromycin-hydroxychloroquine group vs. the placebo group); the sco
83 (95% CI, 34.2 to 37.1) in the clarithromycin-hydroxychloroquine group, and 34.8 (95% CI, 33.4 to 36.2
84 doxycycline group, 96 in the clarithromycin-hydroxychloroquine group, and 98 in the placebo group).
90 stablished DMARDs, such as sulfasalazine and hydroxychloroquine, have also demonstrated efficacy when
92 tudy the adherence of rheumatologists to the hydroxychloroquine (HCQ) dosing guidelines established b
94 nt case-control study suggested a benefit of hydroxychloroquine (HCQ) in lowering the risk of cardiac
97 thalmology recommendations for screening for hydroxychloroquine (HCQ) retinopathy advise objective me
98 ations on screening for chloroquine (CQ) and hydroxychloroquine (HCQ) retinopathy are revised in ligh
99 lysosomotropic agent and autophagy inhibitor hydroxychloroquine (HCQ) synergizes with CCI-779 and led
101 is showed that the combination of dnaJP1 and hydroxychloroquine (HCQ) was superior to the combination
104 re underway combining anticancer agents with hydroxychloroquine (HCQ), but concentrations of HCQ requ
105 investigated whether the antimalarial drug, hydroxychloroquine (HCQ), might affect this prothromboti
106 maximum tolerated dosage of MTX was reached, hydroxychloroquine [HCQ] was added) or parallel triple t
107 isk factors should help physicians prescribe hydroxychloroquine in a manner that will minimize the li
111 articipants into 2 groups: those affected by hydroxychloroquine-induced retinal toxicity and those un
113 e inner retina appears not to be involved in hydroxychloroquine-induced retinopathy to any clinically
114 g patients with rheumatoid arthritis, use of hydroxychloroquine is associated with a reduced risk of
115 herapy with methotrexate, sulfasalazine, and hydroxychloroquine is more effective than either methotr
118 Two retrospective analyses suggest that hydroxychloroquine may prevent congenital heart block in
119 Treatment with a specific FXa inhibitor, hydroxychloroquine or fluvastatin significantly reduced
121 rapy with the addition of sulfasalazine plus hydroxychloroquine (or etanercept, if necessary, after 6
122 atic drugs (methotrexate, sulfasalazine, and hydroxychloroquine) or etanercept plus methotrexate.
123 triple therapy (MTX plus sulfasalazine plus hydroxychloroquine), or step-up from MTX monotherapy to
124 Some patients treated with chloroquine, hydroxychloroquine, or colchicine develop autophagic vac
128 , vigabatrin (Sabril), tamoxifen (Nolvadex), hydroxychloroquine (Plaquenil)/chloroquine (Aralen), ami
129 xplain inhibition of TLR7 and 9 signaling by hydroxychloroquine (Plaquenil; Sanofi-Aventis, Bridgewat
130 TE) and a 12-month course of doxycycline and hydroxychloroquine prophylaxis in patients with signific
132 ocal placoid pigment epitheliopathy (n = 1), hydroxychloroquine retinopathy (n = 1), and macular tela
139 res and long-term follow-up of patients with hydroxychloroquine retinopathy, making it difficult to s
143 New therapeutic agents such as statins, hydroxychloroquine, rituximab, complement inhibitors, an
144 s, we discuss the candidate therapies, i.e., hydroxychloroquine, rituximab, eculizumab, sirolimus, an
146 red or white fields should be acceptable for hydroxychloroquine screening, as long as the clinician i
151 y, 3) cyclosporine + MTX, 4) triple therapy (hydroxychloroquine, sulfasalazine, and MTX), 5) continua
152 t resulted in treatment with > or = 1 DMARD (hydroxychloroquine, sulfasalazine, auranofin, intramuscu
153 binations of methotrexate plus cyclosporine, hydroxychloroquine, sulfasalazine, leflunomide, etanerce
156 endations, long-term users of chloroquine or hydroxychloroquine sulfate should undergo regular visits
158 Decline in CD4 cell count was greater in the hydroxychloroquine than placebo group (-85 cells/muL vs
159 d future clinical trials involving high-dose hydroxychloroquine to improve safety monitoring and pres
160 brane carries a positive prognostic value in hydroxychloroquine toxic effects because it may be assoc
164 itivity and specificity for the detection of hydroxychloroquine toxicity as identified by mfERG, and
166 ily dosing is a cost-effective way to reduce hydroxychloroquine toxicity, but height, weight, and dai
167 e an ACR50 response at 2 years compared with hydroxychloroquine-treated patients (60% compared with 3
169 ean age, 55.7+/-10.4 years; mean duration of hydroxychloroquine treatment, 15.0+/-7.5 years) were div
170 5% CI 1-1.38) were associated with ROM loss, hydroxychloroquine use (OR 11.2, 95% CI 3.7-33) and calc
171 ificantly reduced with increased duration of hydroxychloroquine use (P < .001 for trend); among those
175 nts, each additional month of chloroquine or hydroxychloroquine use was associated with a 2.0% increa
177 .1%) had at least 1 record of chloroquine or hydroxychloroquine use, and 1409 (7.8%) had used chloroq
180 tinal thickness between short- and long-term hydroxychloroquine users (n = 27) in different retinal r
182 e was seen in the SD-OCT images of long-term hydroxychloroquine users until the actual appearance of
183 its in >/=3 of 5 years) among chloroquine or hydroxychloroquine users, including those at highest ris
184 cident diabetes among patients who had taken hydroxychloroquine was 0.62 (95% confidence interval, 0.
185 8 (35.7%), the dose was reduced, in 2 (7.1%) hydroxychloroquine was stopped, but in 16 (57.1%) no act
187 evels, use of glucocorticoids, and nonuse of hydroxychloroquine were all significantly associated wit
188 eatment of mice with the autophagy inhibitor hydroxychloroquine, which is currently being used in sev
189 We studied retrospectively 13 patients using hydroxychloroquine who had undergone both red (FASTPAC)
190 ew was performed to identify patients taking hydroxychloroquine who were screened for toxic effects f
191 uine and by 171 patients who had never taken hydroxychloroquine, with incidence rates of 5.2 per 1000
193 ut TNF inhibitors or hydroxychloroquine; (3) hydroxychloroquine without TNF inhibitors or methotrexat
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