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1 e nucleophilic attack from the primer RNA 3'-hydroxyl.
2 internal guanosine N-2, rather than a ribose hydroxyl.
3 ydroxyl at C6 and the more reactive anomeric hydroxyl.
4 aniline, and amine groups but not as that of hydroxyl.
5 -MS3 can also oxidize the accompanying 7beta-hydroxyl.
6 the donor glycosyl moiety from nucleobase to hydroxyl.
8 ct was attributed to increased alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate (AMPA) throughp
9 uced a significant decrease in alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionic acid receptor (AM
10 ycins are characterized by the presence of a hydroxyl acetic acid and five amino acids including a ra
11 ing algorithms and confirmed by selective 2'-hydroxyl acylation analyzed by primer extension (SHAPE)
12 information, for instance using selective 2'-hydroxyl acylation analyzed by primer extension (SHAPE)
15 usly developed cotranscriptional selective 2-hydroxyl acylation analyzed by primer extension sequenci
19 roach, denoted SHALiPE, couples selective 2'-hydroxyl acylation with lithium ion-based primer extensi
20 dd to glycolaldehyde imine to afford allylic hydroxyl allenes, and allyl boronates add to alkynyl imi
21 se IV; L4) that relies on juxtaposition of 3 hydroxyl and 5 phosphate termini of the strand breaks fo
23 otational-vibrational bands of nitric oxide, hydroxyl and molecular oxygen as signatures of nitrogen,
25 potential source of reactive species such as hydroxyl and peroxy radicals (OH and HO2, "HOx") indoors
26 The inhibition of DNA damage (induced by hydroxyl and peroxyl radicals), copper-induced LDL-chole
27 total phenolics, scavenging activity against hydroxyl and peroxyl radicals, the reducing power and ch
28 d in primary reactions with PFOA showed that hydroxyl and superoxide radicals, which are typically th
33 ion, the O3s path leads to the generation of hydroxyl anions which diffuse on the surface, without ne
34 (30, 60, 90, 120 and 150 ppm) and butylated hydroxyl anisole (200 ppm), were incorporated in anhydro
36 (78.81%), Fe(2+) chelating ability (51.20%), hydroxyl assay (60.95%) and reducing power (0.375nm) was
37 ctivity is metal-dependent and requires a 2'-hydroxyl at both the terminal adenosine and the penultim
38 e, circumventing the more readily accessible hydroxyl at C6 and the more reactive anomeric hydroxyl.
40 of magnitude higher than negatively charged hydroxyl-bearing environmental surfaces, indicating the
44 Ser2, or the phosphate on Ser2 and the Thr4 hydroxyl, can be formed by rotation of an arginine side
45 vity stems from the integration of amide and hydroxyl CEST effects that show base- and acid-catalyzed
47 nstian pH shift, and demonstrate that cation-hydroxyl co-adsorption causes the apparent pH dependence
49 ypes of bonded water (e.g., molecular water, hydroxyl) contained in hydrated minerals by coupling a t
52 report the synthesis of (+/-)-3 and the des-hydroxyl derivative 4 using our previously reported orth
53 actors by restricting the activity of prolyl hydroxyl dioxygenase enzymes, which hydroxylate HIF-1alp
54 hatase (PNKP), which generates 5-phosphate/3-hydroxyl DNA termini that are critical for ligation by t
55 cant decrease in cutin deposition, mid-chain hydroxyl esterification of the dihydroxyhexadecanoic aci
57 pectroscopy and computational modelling, how hydroxyls form from water dissociation at under coordina
58 n additional vinyl group as a precursor of a hydroxyl functionality was synthesized, in which the key
59 is method allows regioselective synthesis of hydroxyl-functionalized aryl and alkyl ketones from simp
60 tal were treated with fluorescently-labeled, hydroxyl-functionalized poly(amidoamine) dendrimer nanop
61 driven self-assembly (CDSA) method [PMVSOH = hydroxyl-functionalized poly(methylvinylsiloxane), P2VP
62 n, we demonstrate the efficient synthesis of hydroxyl-functionalized stilbene and 2-arylbenzo[b]furan
63 s hexaketide with an epimerized nucleophilic hydroxyl group allowed for direct evaluation of the subs
64 cacy for the selective oxidation of a single hydroxyl group among many in unprotected polyol natural
65 se only compounds that contain a carboxyl or hydroxyl group and have moderate steric hindrance were e
66 tabilized by hydrogen bonds between the 5-HT hydroxyl group and lipid headgroups and allows 5-HT to i
67 xtensive interactions between each trehalose hydroxyl group and residues of the cap and core domains
69 ning initiated by the attack of one phenolic hydroxyl group and, then, by addition of one aromatic ph
71 ing, or minimally the stereochemistry of the hydroxyl group at C-16, is crucial for the activity of P
72 lyzed oxidation can single out the secondary hydroxyl group at C3 in glucose, circumventing the more
73 aCaT keratinocytes, suggesting the lack of a hydroxyl group at C44 as a critical feature for PLTXs cy
74 onium moiety appeared more proficient than a hydroxyl group at directing the stereochemical course of
75 efficiently coupled at -40 degrees C to the hydroxyl group at position 3 of glucopyranosyl acceptors
77 ylation of acceptors with more than one free hydroxyl group by 2,3,5,6-tetrabenzoyl galactofuranosyl
79 uch bicyclic compound carrying an equatorial hydroxyl group has activity equal to that of the parent
80 refore, the selective conversion of a single hydroxyl group in natural products into a ketone would e
81 ) decreases their vapor pressure as a second hydroxyl group is incorporated to accelerate their oxida
82 side-chain hydroxyl group of Ser-497 to the hydroxyl group of 5, whereas the unfavorable entropy mig
84 -triphosphate (2'-Az-dATP) onto the tyrosine hydroxyl group of a peptide, which is either tethered to
85 rase responsible for methylation of the meta-hydroxyl group of caffeoyl-coenzyme A (CoA) on the pathw
87 ons suggest that a hydrogen bond between the hydroxyl group of Hzp and a backbone amide carbonyl posi
88 ation of a hydrogen bond from the side-chain hydroxyl group of Ser-497 to the hydroxyl group of 5, wh
89 covalent attachment of sugar moieties to the hydroxyl group of serine or threonine on proteins/peptid
90 300(Sc), I2(I), is located near the bridging hydroxyl group of the [ScO4(OH)2] moiety [I2(I)...H-O =
91 vity for the glycosylation on the equatorial hydroxyl group of the acceptor was obtained thanks to th
93 core, stereocenters at C14 and C15, and the hydroxyl group of the m-tyrosine (m-Tyr) residue as key
95 elA binds the CCA tail to orient the free 3' hydroxyl group of the terminal adenosine towards a beta-
99 determine the effect of the position of the hydroxyl group on the antioxidant properties of flavonoi
100 tify the favoured path, either through the 3-hydroxyl group or through the catecholic moiety in a ser
104 nformations in which hydrogen-bonding to the hydroxyl group results in direction of the epoxidation t
105 the derivatives of flavonoids, which have a hydroxyl group substituted at the R-3 position on the C
107 atalytic function is to lower the pKa of the hydroxyl group, making it a highly effective nucleophile
114 ic acid feet, and "steps" along an isotactic hydroxyl-group-derivatized polyether track by the format
116 sence of other functionalities, such as free hydroxyl groups and amines widely present in biological
119 xygenated hydrocarbons that bear one or more hydroxyl groups comprise a large set of natural and synt
120 acent Au sites was apt to react with surface hydroxyl groups formed from water splitting, leading to
121 -ray quality crystals of five compounds with hydroxyl groups forming five- and six-membered chelation
123 logs revealed the co-operative nature of the hydroxyl groups in mediating both this aqueous glycosyl
124 bicyclic ring I carrying equatorial amino or hydroxyl groups mimicking the bound side chains of neomy
125 Dandante or amine NDamine, carboxyl NDvox or hydroxyl groups NDH and drop-casted or spray-coated onto
128 tive site has an open structure and that the hydroxyl groups of all xylose residues in the active sit
129 ak reversible covalent bonds between vicinal hydroxyl groups of arabitol and boronic acid substituent
130 as been synthesized by connecting the tailed hydroxyl groups of C-propan-3-ol pyrogallol[4]arene with
131 ta, a benzyl etherification of nonesterified hydroxyl groups of glycerol and hydroxy fatty acids was
132 (2+) ions are bridged by the carboxylate and hydroxyl groups of lactate and the carboxylate group of
134 acetylglucosamine (O-GlcNAc) sugar moiety to hydroxyl groups of serine/threonine residues of cytosoli
136 that tetrahedral [Zn(NH3)4](2+) ions bind to hydroxyl groups of the film at a stoichiometric ratio of
137 c apolar pocket that surrounds the C4 and C5 hydroxyl groups of the natural substrate, cause the open
139 photoelectron spectroscopy revealed that the hydroxyl groups on the GONR were removed by the reductiv
140 presence of specific chemical groups such as hydroxyl groups or hydrogens.The synthesis of two-dimens
141 Additionally, other extra-lattice aluminum hydroxyl groups previously discussed in the literature b
143 on that provides an array of surface-exposed hydroxyl groups that bind to polyQ peptides and may disr
147 actions are possible when there are phenolic hydroxyl groups within substrates that contain a second
148 icting common sites of UGT conjugation, like hydroxyl groups, it can also accurately predict the gluc
149 thyris ADH1 catalyzes dehydrogenation of the hydroxyl groups, leading to the subsequent rearrangement
150 charides, deoxysugars, saccharides with free hydroxyl groups, pyranose, and furanose substrates.
151 ess copper, charge compensated by systematic hydroxyl groups, which leads to an open microporous fram
158 with a mechanism involving decomposition of hydroxyl hydroperoxide intermediates followed by hemiace
159 im with two guanidinium units and a phenolic hydroxyl in an ABAH functionalization pattern, effective
160 the interaction being bidentate (both ribose hydroxyls interacting with the carboxylate oxygens), to
162 hat electrostatic interactions and phosphate-hydroxyl ligand exchanges drive protein adsorption on AH
165 nalyses demonstrate that the presence of two hydroxyl moieties in the flavone A-ring backbone are ess
166 e, which is comprised of an ordered array of hydroxyl molecules with molecular water in the second la
167 by these receptors if a single inversion of hydroxyl occurred at C2 or C4 of the sugar or if two or
168 h OsSDR110C-MI3 readily oxidizing the 3alpha-hydroxyl of oryzalexin D, while OsSDR110C-MS3 can also o
169 d kinase activity that phosphorylates the 3'-hydroxyl of phosphoinositides and a protein-kinase activ
170 ilic substitution mechanism, in which the 3'-hydroxyl of the primer attacks the phosphate of the inco
173 tion is carboxylic acid (COOH) approximately hydroxyl (OH) > nitrate (ONO2) > carbonyl (CO) approxima
174 mine foodstuffs' scavenging capacity against hydroxyl (OH) and AAPH radicals, while the third method
175 ropospheric oxidants, such as ozone (O3) and hydroxyl (OH) and peroxy radicals (HO2 + RO2), determine
176 at is offset by a 7% decrease in global mean hydroxyl (OH) concentrations, the primary sink for atmos
177 lkenes, an important nonphotolytic source of hydroxyl (OH) radicals in the atmosphere, proceeds throu
178 direct transfer of primary amino (-NH2) and hydroxyl (-OH) groups to arylmetals in a scalable and en
179 key adsorbed intermediates (hydrogen *H and hydroxyl *OH) at electrified metal-aqueous electrolyte i
180 der all the study environments, the bridging hydroxyl (OHbr) and terminal hydroxyl (OHt) are identifi
181 s, the bridging hydroxyl (OHbr) and terminal hydroxyl (OHt) are identified at 1.1-1.3 eV and 2.1-2.3
182 ng either the oxygen on phospho-Thr4 and the hydroxyl on Ser2, or the phosphate on Ser2 and the Thr4
183 was due to the formation and accumulation of hydroxyl on the catalyst surface, whereas deactivation o
184 ise from hydroxonium species but rather from hydroxyls on extra-lattice aluminol species proximate to
185 sorbed water and its dissociation to surface hydroxyls on oxide surfaces is key to unraveling many ph
186 the authors report a pronounced ordering of hydroxyls on the cleaved (001) surface of Ca3Ru2O7 perov
187 Here we report a pronounced ordering of hydroxyls on the cleaved (001) surface of the Ruddlesden
188 Compounds substituted with an equatorial hydroxyl or amino group in the newly formed ring are con
190 at a possible mechanism for formation of the hydroxyl overlayer involves the mixed adsorption of O2 a
191 (a unique residue for Zta) whose side chain hydroxyl oxygen atom interacts with the two half sites d
192 r PARP1 to attach ADP-ribose groups onto the hydroxyl oxygen of the Ser residues of target substrates
193 alyses reveal highly shifted carboxamide and hydroxyl peaks with intensities that increase and decrea
196 ve enzymatic hydrolysis and was reacted with hydroxyl protected phenolic acids to produce correspondi
199 ap, 5,5-dimethyl-1-pyrroline-N-oxide (DMPO), hydroxyl radical ((*)OH) and sulfate radical anion (SO4(
200 nsitizers from hydroxylating species such as hydroxyl radical ((*)OH) present in dissolved organic ma
201 dicals are recognized to form as products of hydroxyl radical ((*)OH) scavenging by halides, their co
202 els, forming: (1) nitrogen dioxide (NO2) and hydroxyl radical ((*)OH), (2) nitrite (NO2(-)) and oxyge
205 ctivity of the impregnated solids to produce hydroxyl radical (.OH) from H2O2 decomposition was evalu
206 ased mixing ratio of hydroperoxyl radical to hydroxyl radical ([HO2]/[OH]) and increased [NO2]/[NO] w
207 so suggested that SO4(*-) was transformed to hydroxyl radical (HO(*)) and carbonate radical (CO3(*-))
211 xidation and enters the cytoplasm inflicting hydroxyl radical attack on intracellular proteins and DN
212 ation and steady-state concentrations of the hydroxyl radical by cloud chemistry models and for organ
217 complex which might yield Fe(IV) instead of hydroxyl radical formation as suggested in literature.
219 degraded in aqueous systems in presence of a hydroxyl radical generating system such as ascorbic/iron
220 reas ovotransferrin completely inhibited the hydroxyl radical generation by a system containing ascor
221 lysis of voltammograms demonstrated that the hydroxyl radical is a principal contributor to the volta
224 ferrin and ovotransferrin; could prevent the hydroxyl radical mediated degradation of beta-glucan.
227 ous-phase oxidation reaction: iron-catalyzed hydroxyl radical production from hydrogen peroxide (Fent
229 lows mass spectrometry-based high-resolution hydroxyl radical protein footprinting (HR-HRPF) measurem
230 II)-concentrations, absence vs presence of a hydroxyl radical scavenger (dimethyl sulfoxide, DMSO), a
231 trolysine yields decreased in the absence of hydroxyl radical scavengers, suggesting that future rese
232 l as determined by ABTS and DPPH assays, and hydroxyl radical scavenging capacity, reducing power as
234 that the molecules investigated reacted with hydroxyl radical via both HAT and SPLET in the solvents
235 ated Fe(II) represent an important source of hydroxyl radical via the Fenton reaction in cloudwater.
237 d on activity of DPPH radical, ABTS radical, hydroxyl radical, Fe(2+) chelating ability and reducing
238 ment of the contributions of singlet oxygen, hydroxyl radical, hydrogen peroxide, and triplet dissolv
239 f atmospheric oxidants such as ozone and the hydroxyl radical, which controls the self-cleansing capa
242 copies that bound the RPR and site-specific hydroxyl radical-mediated footprinting to localize the K
243 d similar antioxidant properties, except for hydroxyl radical-scavenging activity, higher on green te
249 generation of reactive oxygen species (ROS) [hydroxyl radicals ((*)OH) and hydrogen peroxide (H2O2)]
250 dation process that produces highly reactive hydroxyl radicals (HO(*)) and chlorine radicals (Cl(*))
252 (kO3) (<0.1-7.9 x 10(3) M(-1) s(-1)) or with hydroxyl radicals (k(*)OH) (0.9 x 10(9) - 6.5 x 10(9) M(
253 of nitroblue tetrazolium into formazan, and hydroxyl radicals (OH( *)) were detected by the hydroxyl
256 sphere is initiated primarily by addition of hydroxyl radicals (OH) to C4 or C1 in a ratio 0.57 +/- 0
257 phase oxidation of cis-pinonic acid (CPA) by hydroxyl radicals (OH) was studied using a relative rate
258 to TiO2 to produce three- and four-fold more hydroxyl radicals and hydrogen peroxide, respectively, t
259 r the parameters affecting the production of hydroxyl radicals and their spin trapping with DMPO were
261 te anions or bisulfite anions) with holes or hydroxyl radicals are the active species for MO photodeg
263 nd DOM isolates revealed that reactions with hydroxyl radicals dominated the transformation of tested
265 se results demonstrate that plasma-generated hydroxyl radicals from water can be used to map protein
266 omolecules), that generates micros bursts of hydroxyl radicals from water, to measure changes in prot
268 hophorothioated DNA reacted to both H2O2 and hydroxyl radicals in vivo, and protected genomic DNA as
270 Bimolecular reaction rate constants with hydroxyl radicals ranged from (2.04 +/- 0.37) x 10(9) to
271 phenolics, flavonoids, ABTS free radical and hydroxyl radicals scavenging and anti-inflammatory activ
275 processes such as photolysis, reactions with hydroxyl radicals, and aerosol uptake were found to be i
276 xamined as hydrogen donors to DPPH, ABTS and hydroxyl radicals, and as electron donors in the FRAP as
277 contents and scavenging of ABTS(+), DPPH and hydroxyl radicals, as well as metal chelation of the sol
278 ess (e.g., hydrogen peroxide, superoxide and hydroxyl radicals, nitric oxide, ascorbic acid, and glut
279 found able to scavenge superoxide anion and hydroxyl radicals, organic nitro-radicals (ABTS, DPPH) a
280 ltraviolet (UV) radiation (lambda=254nm) and hydroxyl radicals, the intensity of the emitted photolum
286 the large and small subunits, wherein the 6'-hydroxyl substituent in ring I serves as a key determina
287 icient binding at the DDC site, at least one hydroxyl substituent must be present at the aromatic rin
290 educed molecular weight, increased amount of hydroxyl terminal groups and ferric reducing activities.
292 AuNPs encapsulated within sixth-generation, hydroxyl-terminated, poly(amidoamine) dendrimers (G6-OH
295 3'-phosphoryl of HP-MBs was hydrolyzed to 3'-hydroxyl, thus serving as primers to initiate the polyme
296 enhances activity by positioning the Tyr157 hydroxyl to enable proper Cys binding, proper oxygen bin
297 ting the nucleophile by deprotonating the 2'-hydroxyl to initiate the reaction (phosphoester transfer
298 that synchronous proton transfer from the 2'-hydroxyl to the departing phosphate group facilitates cl
300 opy images show a pronounced ordering of the hydroxyls with (2 x 1), c(2 x 6), (1 x 3), and (1 x 1) p
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