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1 cid adenine dinucleotide at the adenosine 3'-hydroxyl group.
2 e ring to substitute the amino group with an hydroxyl group.
3 ies on the carbon position of the acyl chain hydroxyl group.
4 at funnels to its narrowest region at the C3-hydroxyl group.
5 tated by the electron-donating nature of the hydroxyl group.
6 res that are highly stable because of the 2'-hydroxyl group.
7 ylation at a secondary C-H bond gamma to the hydroxyl group.
8 r connecting the metal chelating unit to the hydroxyl group.
9 on despite containing the equivalent of a 3'-hydroxyl group.
10 rogen bonded to this residue via its 17alpha-hydroxyl group.
11 ion of proteins at the Ser or Thr side chain hydroxyl group.
12 te)s with a functionalizable pendant primary hydroxyl group.
13 ng a side-arm and a potentially nucleophilic hydroxyl group.
14 phile by a hydrogen bond from the catalyst's hydroxyl group.
15 vel polar interaction mediated by the RJW100 hydroxyl group.
16 s achieved with the substrate bearing a free hydroxyl group.
17 ase yielding an intermediate with a tertiary hydroxyl-group.
18 s acidic surface domains depleted in surface hydroxyl groups.
19 ,3-dioxane structures with lignin side-chain hydroxyl groups.
20 hydration or the number of crystallographic hydroxyl groups.
21 f kanamycin B analogues alkylated at various hydroxyl groups.
22 undergo acid-base chemistry with the silica hydroxyl groups.
23 ive exchange of C-H protons adjacent to free hydroxyl groups.
24 ions because of the presence of aldehyde and hydroxyl groups.
25 avenging activity, due to the high number of hydroxyl groups.
26 hydrogen originates exclusively from glycol hydroxyl groups.
27 oxide thin film with a controlled density of hydroxyl groups.
28 esistance to fouling after the activation of hydroxyl groups.
29 fragmentation occurs even in the absence of hydroxyl groups.
30 ction processing of substrates with inverted hydroxyl groups.
31 thiiranium ions in competition with phenolic hydroxyl groups.
32 especially those that lack adjacent aromatic hydroxyl groups.
33 saccharides, and saccharides containing free hydroxyl groups.
34 f detected metabolites were those containing hydroxyl groups.
35 hanism with participation of the most acidic hydroxyl groups: 7-OH in SIL and 7-OH and 3-OH in DHS.
36 trisubstituted alkenes was achieved through hydroxyl group activation, an approach that also enables
38 s hexaketide with an epimerized nucleophilic hydroxyl group allowed for direct evaluation of the subs
39 cacy for the selective oxidation of a single hydroxyl group among many in unprotected polyol natural
42 se only compounds that contain a carboxyl or hydroxyl group and have moderate steric hindrance were e
43 tabilized by hydrogen bonds between the 5-HT hydroxyl group and lipid headgroups and allows 5-HT to i
44 ly suggest that hydrogen bonding templates a hydroxyl group and Pd addition across the alkene and pro
45 xtensive interactions between each trehalose hydroxyl group and residues of the cap and core domains
46 of the propeptide by deprotonating the Thr1 hydroxyl group and that both residues together with Asp1
48 the noncovalent interaction of the substrate hydroxyl group and the chiral cationic palladium catalys
49 duct selectivity originating from a resident hydroxyl group and the critical choice of the reaction s
50 duces ligand formation between oxygen on the hydroxyl group and the zinc ions, which expands the stab
51 ning initiated by the attack of one phenolic hydroxyl group and, then, by addition of one aromatic ph
53 sence of other functionalities, such as free hydroxyl groups and amines widely present in biological
55 followed by peracetylation of the remaining hydroxyl groups and separation of isomers resulted in th
56 trimetaphosphate to triphosphorylate RNA 5'-hydroxyl groups and suggested that RNA world organisms c
57 ces, but it is not well-understood how these hydroxyl groups and their distribution on a surface affe
59 eroid "reduced pregnenolone" (containing two hydroxyl groups) and its d4-analogue provide evidence of
61 orm of carboxyfluorescein in which 3' and 6' hydroxyl groups are masked as acetate esters (CFDA).
65 in situ intramolecular oxacyclization by the hydroxyl group as a pre-existing nucleophile of the alco
66 of a fluorine atom adjacent to the phenolic hydroxyl group as in 3w, 3z, 3aa, and 3bb to strengthen
67 we identify the coverage of reactive surface hydroxyl groups as a suitable descriptor for the OER act
68 0, IC50 = 11 muM) revealed the importance of hydroxyl groups as hydrogen-bond donors for PXR antagoni
70 titania likely donates protons from surface hydroxyl groups as well as supplying electrons and holes
71 ium group is lower than that of the phenolic hydroxyl group, as is the case for the alpha-amino-prote
72 ective reductive intramolecular cyclization, hydroxyl group-assisted in situ N-Boc-deprotection, sele
73 ing, or minimally the stereochemistry of the hydroxyl group at C-16, is crucial for the activity of P
74 lyzed oxidation can single out the secondary hydroxyl group at C3 in glucose, circumventing the more
76 aCaT keratinocytes, suggesting the lack of a hydroxyl group at C44 as a critical feature for PLTXs cy
77 onium moiety appeared more proficient than a hydroxyl group at directing the stereochemical course of
78 4 belongs to the SDR family and oxidizes the hydroxyl group at position 17 of estradiol and 5-androst
81 efficiently coupled at -40 degrees C to the hydroxyl group at position 3 of glucopyranosyl acceptors
89 the inter- or intramolecular reaction with a hydroxyl group belonging to an alcohol, a phenol or an a
90 modulators BPAM97 (2) and BPAM344 (3) into a hydroxyl group (BPAM557 (4) and BPAM521 (5), respectivel
91 ylation of acceptors with more than one free hydroxyl group by 2,3,5,6-tetrabenzoyl galactofuranosyl
92 ilitated by the coordination of the reactive hydroxyl group by Ca(2+) in the active site, lowering th
95 thered primary, secondary, and tertiary free hydroxyl groups can all react to give the corresponding
96 show that molecules containing at least two hydroxyl groups can be converted into methanol, which de
97 xygenated hydrocarbons that bear one or more hydroxyl groups comprise a large set of natural and synt
98 for example, CH(2)-units, aromatic rings or hydroxyl groups, contribute differently to the sorption
99 dation reactions and the presence of vicinal hydroxyl groups correlated with flavonoid reactivity in
101 6 dyad, proposed to be involved in substrate hydroxyl group deprotonation, a critical requirement for
103 ic acid feet, and "steps" along an isotactic hydroxyl-group-derivatized polyether track by the format
104 y the axial or equatorial orientation of two hydroxyl groups differentiating among these isomers in t
106 proton of the phosphinic acid protonates the hydroxyl group, enhancing the leaving group ability.
107 llowed by epoxidation on the face syn to the hydroxyl group exclusively; reduction then provided eith
111 acent Au sites was apt to react with surface hydroxyl groups formed from water splitting, leading to
112 -ray quality crystals of five compounds with hydroxyl groups forming five- and six-membered chelation
113 coordinate bonds with the zinc ion, and the hydroxyl group from CQ formed an effective hydrogen bond
115 ated by the stereoselective incorporation of hydroxyl groups, generating cis-4- and cis-5-aminocyclop
116 uch bicyclic compound carrying an equatorial hydroxyl group has activity equal to that of the parent
117 drophobic substituents are attached to the 6-hydroxyl groups, has been the subject of speculation.
118 h cleave a methylenedioxy bridge leaving two hydroxyl groups, have previously not been reported in pl
119 lics was evaluated in model solutions, where hydroxyl groups, hydrophobic bonding and steric hindranc
120 sing because of the directing influence of a hydroxyl group in C horizontal lineC bond hydrogenation.
121 refore, the selective conversion of a single hydroxyl group in natural products into a ketone would e
122 s efficiently prevented by deprotonating the hydroxyl group in position 2 of the glyconitriles during
123 tes are open enough to accommodate the extra hydroxyl group in RNA, further supporting our conclusion
125 d by the enzyme or the replacement of the C3 hydroxyl group in the natural substrate by an amino grou
126 distance from the aromatic ring, whereas the hydroxyl group in the para-position is not essential, bu
128 rogen (D/H) ratio in strongly bound water or hydroxyl groups in ancient martian clays retains the imp
129 was associated with carboxylic and phenolic hydroxyl groups in biochars BP300-450, whereas 91% of so
131 trolled subtle reactivity differences of the hydroxyl groups in carbohydrates were utilized to quickl
132 logs revealed the co-operative nature of the hydroxyl groups in mediating both this aqueous glycosyl
134 of compound 3, focusing on the carbamoyl and hydroxyl groups in the distal and proximal phenyl rings.
137 mpared with the aim of investigating how the hydroxyl groups in their structures govern the biologica
138 ioxidant capacity because of the presence of hydroxyl groups in various configurations and numbers wi
139 le of the serine 364, and more precisely its hydroxyl group, in coupling sodium and substrate fluxes.
140 er, RdmB, it catalyzes the introduction of a hydroxyl group, in the case of NDUFAF5, into Arg-73 in t
141 RNase H2 to selectively create ligatable 3'-hydroxyl groups, in contrast to alternative methods that
142 ) decreases their vapor pressure as a second hydroxyl group is incorporated to accelerate their oxida
143 icting common sites of UGT conjugation, like hydroxyl groups, it can also accurately predict the gluc
144 thyris ADH1 catalyzes dehydrogenation of the hydroxyl groups, leading to the subsequent rearrangement
145 ded to the calcite surface through its polar hydroxyl group, leaving the hydrophobic ends of the etha
147 atalytic function is to lower the pKa of the hydroxyl group, making it a highly effective nucleophile
149 ts suggested that the number and position of hydroxyl groups may increase or decrease the protective
150 bicyclic ring I carrying equatorial amino or hydroxyl groups mimicking the bound side chains of neomy
151 Dandante or amine NDamine, carboxyl NDvox or hydroxyl groups NDH and drop-casted or spray-coated onto
154 und useful in the in situ blocking of the C3-hydroxyl group of 2,4-di-O-TBDPS protected 1,6-anhydrogl
155 side-chain hydroxyl group of Ser-497 to the hydroxyl group of 5, whereas the unfavorable entropy mig
158 -triphosphate (2'-Az-dATP) onto the tyrosine hydroxyl group of a peptide, which is either tethered to
159 ron ion (Fea), which is proposed to bind the hydroxyl group of a postulated intermediate in the last
160 calculations reveal that protonation of the hydroxyl group of aliphatic alcohols transforms the C-O
162 rase responsible for methylation of the meta-hydroxyl group of caffeoyl-coenzyme A (CoA) on the pathw
166 ons suggest that a hydrogen bond between the hydroxyl group of Hzp and a backbone amide carbonyl posi
167 m (Sorghum bicolor; SbCOMT) methylates the 5-hydroxyl group of its preferred substrate, 5-hydroxyconi
169 olecular dynamic analysis indicated that the hydroxyl group of monophenolic substrates can bind to Cu
170 owth, characterized by acetylation of the C6 hydroxyl group of N-acetylmuramic acid in the PG glycan
171 ation of a hydrogen bond from the side-chain hydroxyl group of Ser-497 to the hydroxyl group of 5, wh
173 covalent attachment of sugar moieties to the hydroxyl group of serine or threonine on proteins/peptid
174 tomyces venezuelae is able to oxidize the C3 hydroxyl group of TDP-D-quinovose to the corresponding k
175 tributed to a much stronger H-bond between a hydroxyl group of TETROL and the carbonyl group of the (
176 300(Sc), I2(I), is located near the bridging hydroxyl group of the [ScO4(OH)2] moiety [I2(I)...H-O =
177 vity for the glycosylation on the equatorial hydroxyl group of the acceptor was obtained thanks to th
178 Asp(A117) determines the orientation of the hydroxyl group of the acyl-CoA esters by H-bond formatio
183 core, stereocenters at C14 and C15, and the hydroxyl group of the m-tyrosine (m-Tyr) residue as key
184 transfer of the methyl group from SAM to one hydroxyl group of the myricetin in a cation-dependent ma
186 acidic residues, water molecules, and the 3'-hydroxyl group of the primer so that the A metal is in a
190 elA binds the CCA tail to orient the free 3' hydroxyl group of the terminal adenosine towards a beta-
192 esis and by seeing close contact between the hydroxyl group of this residue and the azaribose moiety
196 tive site has an open structure and that the hydroxyl groups of all xylose residues in the active sit
197 ak reversible covalent bonds between vicinal hydroxyl groups of arabitol and boronic acid substituent
198 as been synthesized by connecting the tailed hydroxyl groups of C-propan-3-ol pyrogallol[4]arene with
199 erial cellulose nanopaper are reduced by the hydroxyl groups of cellulose nanofibers, acting as the r
201 ta, a benzyl etherification of nonesterified hydroxyl groups of glycerol and hydroxy fatty acids was
202 (2) bonds and removes some of the oxygen and hydroxyl groups of GO, which initiates the evolution of
203 (2+) ions are bridged by the carboxylate and hydroxyl groups of lactate and the carboxylate group of
206 bohydrate post-translational modification on hydroxyl groups of serine and/or threonine residues of c
208 acetylglucosamine (O-GlcNAc) sugar moiety to hydroxyl groups of serine/threonine residues of cytosoli
211 y synthesizing phosphoramidites in which the hydroxyl groups of the cross-linked product were orthogo
212 that tetrahedral [Zn(NH3)4](2+) ions bind to hydroxyl groups of the film at a stoichiometric ratio of
213 c apolar pocket that surrounds the C4 and C5 hydroxyl groups of the natural substrate, cause the open
214 rst time, and surprisingly only two of three hydroxyl groups of the neutral aliphatic triols are foun
220 ed the differentiation between the secondary hydroxyl groups OH-3 and OH-5 of 1,2-cis or 1,2-trans d-
221 oordination of calcium by the two equatorial hydroxyl groups, OH3 and OH4, at the non-reducing end.
224 determine the effect of the position of the hydroxyl group on the antioxidant properties of flavonoi
226 As a result, the introduction of a meta hydroxyl group on the C4 anilino ring was computed to be
227 s reveal mechanisms by which the sacrificial hydroxyl group on the chromanol group can trap lipid per
228 ading structural model predicts that the C2' hydroxyl group on the mycosamine appendage is critical f
229 of ATP demonstrated the importance of the 2' hydroxyl group on the ribose ring in determining agonist
231 w)/M(n) < 1.2), bearing precisely one or two hydroxyl groups on one chain end and optionally a dye-la
233 WASP, where the number and configuration of hydroxyl groups on the acyl side chain impacted the degr
234 idues as well as changes in the positions of hydroxyl groups on the beta-side of the steroid core of
235 photoelectron spectroscopy revealed that the hydroxyl groups on the GONR were removed by the reductiv
236 d (FTIR) spectroscopy suggested more surface hydroxyl groups on the NCC than the MCC particles and co
238 The effects of the third "noninteracting" hydroxyl groups on the structures and binding constants
239 tify the favoured path, either through the 3-hydroxyl group or through the catecholic moiety in a ser
240 presence of specific chemical groups such as hydroxyl groups or hydrogens.The synthesis of two-dimens
241 Structural characteristics (positioning of hydroxyl group) or partitioning behaviour between the em
244 c site and further demonstrates that the A76 hydroxyl groups participate in post-transfer editing onl
247 y the trans-azobenzene molecule with the two hydroxyl groups pointing into opposite directions is ads
250 Additionally, other extra-lattice aluminum hydroxyl groups previously discussed in the literature b
251 charides, deoxysugars, saccharides with free hydroxyl groups, pyranose, and furanose substrates.
252 of the diaxial conformation of the C4 and C5 hydroxyl groups recognized by the enzyme or the replacem
256 glycerol cluster indicate that the glycerol hydroxyl groups reorient around the Na atom as it makes
258 this phenomenon, a lead compound FG03 with a hydroxyl group replacing the 3''-NH2 group of kanamycin
259 nformations in which hydrogen-bonding to the hydroxyl group results in direction of the epoxidation t
260 The data suggested that compounds having a p-hydroxyl group showed moderate 2,2-diphenyl-1-picrylhydr
263 the derivatives of flavonoids, which have a hydroxyl group substituted at the R-3 position on the C
264 ts metabolites were compared on the basis of hydroxyl group substitution and amine ionization to eluc
265 I, and H2BDI possessing both para- and ortho-hydroxyl groups such that the inherent rotational motion
266 ross-linked polymer multilayers that present hydroxyl groups suitable for conventional phosphoramidit
267 -diene-3,20-dion e), do not have the 17alpha-hydroxyl group that characterizes dexamethasone (Dex; 9a
269 on that provides an array of surface-exposed hydroxyl groups that bind to polyQ peptides and may disr
270 , consists of negatively charged carboxyl or hydroxyl groups that limit attractive forces with the ce
271 ctron-deficient alkynes or alkynes with free hydroxyl groups, the coordination of alkynes is stronger
272 n a manner that buries the cholesterol 3beta-hydroxyl group; they also bind tightly to NPC1 and NPC2
273 ll electrophilic reagents that react with 2'-hydroxyl groups to interrogate RNA structure at single-n
274 cess involving nucleophilic addition of free hydroxyl groups to the carbamate linkages and exhibits a
275 ation reactions mainly involved oxidation of hydroxyl groups to the corresponding carboxylic acids.
276 he intramolecular nucleophilic attack of the hydroxyl group took place on the alkyne moiety in a high
277 ceptors through hydrogen bonding with B(OH)2 hydroxyl groups toward Cl(-), Br(-), HSO4(-), and AcO(-)
278 Vitamin D3 metabolites lacking a 1alpha-hydroxyl group (vitamin D3, 25-hydroxyvitamin D3, and 24
281 framework bearing pendent proton-responsive hydroxyl groups was prepared and metalated with Ru(II) a
283 ituted propargyl diols possessing a tertiary hydroxyl group were synthesized in a single-pot operatio
285 the graphene oxide were destroyed, and more hydroxyl groups were generated, transforming the graphen
289 A-1(O2') starts attacking the phosphate as a hydroxyl group, which is hydrogen-bonded to deprotonated
290 fected the rates of biotransformation of the hydroxyl groups, which in some cases resulted in greater
291 ess copper, charge compensated by systematic hydroxyl groups, which leads to an open microporous fram
292 logous ester 27 allowed to introduce the C13 hydroxyl group with a high stereoselectivity in the hali
297 ole-scavenging by surface water molecules or hydroxyl groups, with associated radical formation.
298 actions are possible when there are phenolic hydroxyl groups within substrates that contain a second
299 -selective phosphorylation of three distinct hydroxyl groups within the complex glycopeptide antibiot
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