ライフサイエンスコーパス: hydroxymethyltransferase

1 -THF) is formed by a side reaction of serine hydroxymethyltransferase.

2 two tRNA synthetases, and a putative serine hydroxymethyltransferase.

3 al folate-dependent enzymes including serine hydroxymethyltransferase.

4 The 5'-untranslated region (UTR) of serine hydroxymethyltransferase 1 (SHMT1) contains an internal

5 Serine hydroxymethyltransferase 1 (SHMT1) expression limits rat

6 Serine hydroxymethyltransferase 1 (SHMT1) is an essential scaff

7 de novo biosynthesis is regulated by serine hydroxymethyltransferase 1 (SHMT1).

8 nd repair and consists of the enzymes serine hydroxymethyltransferase 1 and 2alpha (SHMT1 and SHMT2al

9 PSPH)) and de novo glycine synthesis (serine hydroxymethyltransferase 2 (SHMT2)).

10 0 kDa chloroplast membrane protein, a serine hydroxymethyltransferase, a nuclease, and two proteins o

11 -stimulated (35%; P=0.004) lymphocyte serine hydroxymethyltransferase activities in vitro.

12 hat this assay can be used to measure serine hydroxymethyltransferase activity at 10(-8) to 10(-3)M (

13 hat 5-formyltetrahydrofolate inhibits serine hydroxymethyltransferase activity in vivo and that serin

14 , the 5,10-CH(2)-H(4)PteGlu formed by serine hydroxymethyltransferase activity is reduced to 5-CH(3)-

15 vel HPLC-based fluorometric assay for serine hydroxymethyltransferase activity.

16 was confirmed by the activation of aposerine hydroxymethyltransferase after release of the ligand by

17 ternary structure of liganded E. coli serine hydroxymethyltransferase also differs in symmetry and re

18 The gene encodes a serine hydroxymethyltransferase, an enzyme that is ubiquitous i

19 the other two enzymes in the cytosol, serine hydroxymethyltransferase and C1-tetrahydrofolate synthas

20 dylate synthesis, and suggesting that serine hydroxymethyltransferase and FTHFS compete for a limitin

21 e the folate cofactor binding site in serine hydroxymethyltransferase and the differences in orientat

22 s encoding a glycine cleavage system, serine hydroxymethyltransferase, and serine dehydratase.

23 The active serine hydroxymethyltransferase, and two other enzymes that for

24 in vitro folding of Escherichia coli serine hydroxymethyltransferase at 4 degrees C, both monomer an

25 The maturation of serine hydroxymethyltransferase by ICP55 is unusual, as it invo

26 o be the viable in vivo substrate for serine hydroxymethyltransferase-catalyzed formation of 5-formyl

27 the rate of (i) tetrahydrofolate-independent hydroxymethyltransferase chemistry between formaldehyde

28 otent inhibitor of the Gly decarboxylase/Ser hydroxymethyltransferase complex.

29 Cytoplasmic serine hydroxymethyltransferase (cSHMT) enzyme levels are eleva

30 associated with decreased cytoplasmic serine hydroxymethyltransferase (cSHMT) expression in MCF-7 cel

31 The human cytoplasmic serine hydroxymethyltransferase (CSHMT) gene was isolated, sequ

32 Cytoplasmic serine hydroxymethyltransferase (cSHMT) is a tetrameric, pyrido

33 region (UTR) of the human cytoplasmic serine hydroxymethyltransferase (cSHMT) message is alternativel

34 The influence of cytoplasmic serine hydroxymethyltransferase (cSHMT) on this competition was

35 ferential partitioning of cytoplasmic serine hydroxymethyltransferase (cSHMT)-derived methylenetetrah

36 e folate-dependent enzyme cytoplasmic serine hydroxymethyltransferase (cSHMT).

37 uctase [MTHFR] and C1420T cytoplasmic serine hydroxymethyltransferase [cSHMT]).

38 Serine hydroxymethyltransferase (EC 2.1.2.1), a member of the a

39 arrier protein transacylase and ketopantoate hydroxymethyltransferase, enzymes that are required for

40 the transcription of the cytoplasmic serine hydroxymethyltransferase gene (SHMT1).

41 an indirect consequence of damage to serine hydroxymethyltransferase (GlyA; E.C. 2.1.2.1).

42 g4 gene encodes a predicted cytosolic serine hydroxymethyltransferase (GmSHMT08); however, the novel

43 The panB gene that encodes ketopantoate hydroxymethyltransferase has been cloned from Mycobacter

44 o folding pathway of Escherichia coli serine hydroxymethyltransferase has both monomer and dimer inte

45 2.4 A resolution of Escherichia coli serine hydroxymethyltransferase in ternary complex with glycine

46 Ketopantoate hydroxymethyltransferase (KPHMT) and pantothenate synthe

47 enzymic reactions catalysed by ketopantoate hydroxymethyltransferase (KPHMT), L: -aspartate-alpha-de

48 The human mitochondrial serine hydroxymethyltransferase (mSHMT) gene was isolated, sequ

49 A cDNA clone for mitochondrial serine hydroxymethyltransferase (mSHMT) that was capable of par

50 to sequences in rabbit mitochondrial serine hydroxymethyltransferase (mSHMT).

51 However, addition of either serine hydroxymethyltransferase or C1-tetrahydrofolate synthase

52 enase reaction to an excess of either serine hydroxymethyltransferase or C1-tetrahydrofolate synthase

53 ys were viable and lacked cytoplasmic serine hydroxymethyltransferase protein, confirming that mimosi

54 a protein with sequence similarity to serine hydroxymethyltransferases, resulting in the proposal tha

55 characterized a family of Arabidopsis serine hydroxymethyltransferase (SHM) genes.

56 xpectedly, mutation of both cytosolic serine hydroxymethyltransferase (SHM2) and one-carbon tetrahydr

57 sed fluorometric method for measuring serine hydroxymethyltransferase (SHMT) activity toward formatio

58 several with defects in mitochondrial serine hydroxymethyltransferase (SHMT) activity.

59 ed via a second catalytic activity of serine hydroxymethyltransferase (SHMT) and strongly inhibits SH

60 Serine hydroxymethyltransferase (SHMT) catalyzes the reversible

61 Serine hydroxymethyltransferase (SHMT) catalyzes the reversible

62 Serine hydroxymethyltransferase (SHMT) catalyzes the reversible

63 Serine hydroxymethyltransferase (SHMT) catalyzes the reversible

64 Serine hydroxymethyltransferase (SHMT) from all sources tested

65 Serine hydroxymethyltransferase (SHMT) from plant mitochondria

66 rofolate dehydrogenase 1 (MTHFD1) and serine hydroxymethyltransferase (SHMT) generate 5,10-methylenet

67 Serine hydroxymethyltransferase (SHMT) is a pyridoxal 5'-phosph

68 Serine hydroxymethyltransferase (SHMT) is a pyridoxal phosphate

69 Mammalian serine hydroxymethyltransferase (SHMT) is a tetrameric, pyridox

70 Serine hydroxymethyltransferase (SHMT) is the major provider of

71 folding mechanism of Escherichia coli serine hydroxymethyltransferase (SHMT) showed that the final ra

72 amate forms to rabbit liver cytosolic serine hydroxymethyltransferase (SHMT) were determined by a com

73 netetrahydrofolate reductase (MTHFR), serine hydroxymethyltransferase (SHMT), and cystathionine beta-

74 Mitochondrial serine hydroxymethyltransferase (SHMT), combined with glycine d

75 based inhibitors targeting the enzyme serine hydroxymethyltransferase (SHMT), designed to improve mic

76 Nevertheless for serine hydroxymethyltransferase (SHMT), one of the key enzymes

77 is, a pathway composed of the enzymes serine hydroxymethyltransferase (SHMT), thymidylate synthase (T

78 F, a slow, tight-binding inhibitor of serine hydroxymethyltransferase (SHMT), was enriched in nuclei,

79 y observed for reactions catalyzed by serine hydroxymethyltransferase (SHMT).

80 Serine hydroxymethyltransferase (SHMT; EC 2.1.2.1) catalyzes th

81 res of the human and rabbit cytosolic serine hydroxymethyltransferases (SHMT) confirmed their close s

82 ted at the genes encoding one or both serine hydroxymethyltransferases (SHMT) or at the genes encodin

83 se-thymidylate synthase, dhfr-ts, and serine hydroxymethyltransferase, shmt) gave the most abundant t

84 onine synthase (MS A2756G), cytosolic serine hydroxymethyltransferase (SHMT1 C1420T), and a double (2

85 reductase (MTHFR 677C>T and 1298A>C); serine hydroxymethyltransferase (SHMT1 C1420T); reduced folate

86 tide transformylase (ATIC) 347GG, and serine hydroxymethyltransferase (SHMT1) 1420CC were measured an

87 Serine hydroxymethyltransferase (SHMT1) partitions folate-deriv

88 Cytoplasmic serine hydroxymethyltransferase (SHMT1) regulates the partition

89 lioblastoma multiforme, mitochondrial serine hydroxymethyltransferase (SHMT2) and glycine decarboxyla

90 rough the activities of mitochondrial serine hydroxymethyltransferase (SHMT2), thymidylate synthase (

91 with the unliganded rabbit cytosolic serine hydroxymethyltransferase structure identifies changes in

92 l 5'-phosphate is used to activate aposerine hydroxymethyltransferase to form the catalytically activ

93 o of specific proteins indicated that serine hydroxymethyltransferase was affected in icp55.

94 portional to the amount of active holoserine hydroxymethyltransferase, which is a measure of the amou