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1 e peroxyl that gives the trans,trans-product hydroxyoctadecadienoic acid.
2 take/metabolism to the mitogenic molecule 13-hydroxyoctadecadienoic acid.
3 n of 15-LOX-1 and its metabolic product 13-S-hydroxyoctadecadienoic acid.
4 hifted metabolism to 15-LO metabolite, 13(S)-hydroxyoctadecadienoic acid.
5 traenoic acids and linoleic acid to EOAs and hydroxyoctadecadienoic acids.
6 In addition, the reduced products, 13-( S)-hydroxyoctadecadienoic acid (13-HODE) and 12-( S)-hydrox
7 oxidized low-density lipoprotein, such as 13-hydroxyoctadecadienoic acid (13-HODE) and 15-hydroxyeico
8 ubsequent conversion of LA to the mitogen 13-hydroxyoctadecadienoic acid (13-HODE) in vivo and during
9 ydroxyeicosatetraenoic acid (15-HETE) and 13-hydroxyoctadecadienoic acid (13-HODE) which are agonists
11 linoleic acid (LA) and its metabolism to 13-hydroxyoctadecadienoic acid (13-HODE), an important mito
12 addition of the allosteric effector, 13-(S)-hydroxyoctadecadienoic acid (13-HODE), and no allosteric
13 se-1 (15-LOX-1) protein and its product 13-S-hydroxyoctadecadienoic acid (13-S-HODE) are decreased; a
17 xogenously added 15-LO-1 metabolites, 13-(S)-hydroxyoctadecadienoic acid, 13-(R)-hydroxyoctadecadieno
18 oxidized linoleic acid metabolites 9- and 13-hydroxyoctadecadienoic acid (9- and 13-HODE) are formed
19 xidized linoleic acid metabolites, such as 9-hydroxyoctadecadienoic acid (9-HODE) that potently activ
20 oxygenated at the C(9) position, including 9-hydroxyoctadecadienoic acid (9-HODE), a potent ligand of
22 ss (assessed by measuring fatty acid-derived hydroxyoctadecadienoic acid and protein carbonyl content
23 , 13-(S)-hydroxyoctadecadienoic acid, 13-(R)-hydroxyoctadecadienoic acid, and 13-(S)-hydroperoxyoctad
24 nase-1 (15-LOX-1) and its main product, 13-S-hydroxyoctadecadienoic acid, are decreased in human colo
25 nduced apoptosis, which was restored by 13-S-hydroxyoctadecadienoic acid but not by its parent compou
26 CO2-induced ischemia and that LA-derived 13-hydroxyoctadecadienoic acid, but not LA, increase somati
27 and 15-hydroxyeicosatetraenoic acid or 13(S)-hydroxyoctadecadienoic acid formation correlates with ce
28 pounds contained DHA esterified to 9- and 13-hydroxyoctadecadienoic acid (HLA) or 14-hydroxydocosahex
29 significant increase in the concentration of hydroxyoctadecadienoic acid (HODE) metabolites, indicati
30 to 5% of the LA taken up is converted to 13-hydroxyoctadecadienoic acid (HODE), an agent that enhanc
32 cluding 15-HETE, 12-HETE, 5-HETE, as well as hydroxyoctadecadienoic acids (HODEs), including 13-HODE
34 ticular hydro(pero)xyeicosatetraenoic acids, hydroxyoctadecadienoic acids, hydroxydocosahexaenoic aci
35 d lipids such as hydroxyeicosatetraenoic and hydroxyoctadecadienoic acids is well established in vasc
36 ide hydroxamic acid-induced increase in 13-S-hydroxyoctadecadienoic acid levels, growth inhibition, d
37 netics, aberrant crypt foci, eicosanoids and hydroxyoctadecadienoic acids, ornithine decarboxylase, t
38 eic acid, specifically the ratio of 13- to 9-hydroxyoctadecadienoic acid, was identified as a potenti
39 r-activated receptor gamma ligands 13- and 9-hydroxyoctadecadienoic acid were increased in lymphocyte
40 Plasma levels of hydroxyeicosatetraenoic and hydroxyoctadecadienoic acids were significantly elevated
41 ed by epidermal 15-lipoxygenase to mainly 13-hydroxyoctadecadienoic acid, which functionally exerts a
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