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3 red with 25-hydroxyvitamin D >/=30 ng/ml, 25-hydroxyvitamin D <20 ng/ml was associated with a greater
4 itamin D was categorized as deficiency in 25-hydroxyvitamin D (</= 15 ng/mL), insufficiency (15-30 ng
5 h symptomatic knee osteoarthritis and low 25-hydroxyvitamin D (12.5-60 nmol/L) were enrolled from Jun
6 etermine the association between maternal 25-hydroxyvitamin D (25(OH)D) and the risk of spontaneous p
7 ty of single or predicted measurements of 25-hydroxyvitamin D (25(OH)D) concentration is unknown, as
8 vitamin D status (measured by circulating 25-hydroxyvitamin D (25(OH)D) concentration), adiposity, an
15 ated in dairy foods, and predicted plasma 25-hydroxyvitamin D (25(OH)D) levels were associated with i
17 , (2) these associations were modified by 25-hydroxyvitamin D (25(OH)D) status and explained by infla
18 izing the originally measured serum total 25-hydroxyvitamin D (25(OH)D) values from Third National He
19 e examined the association between yearly 25-hydroxyvitamin D (25(OH)D), 1,25-dihydroxyvitamin D (1,2
21 ified SNPs, circulating concentrations of 25-hydroxyvitamin D (25(OH)D), and prostate cancer (3,811 c
22 dian eGFR 51 ml/min per 1.73 m(2)), serum 25-hydroxyvitamin D (25(OH)D), FGF-23, and Klotho levels we
24 investigated whether the plasma level of 25-hydroxyvitamin D (25-OHD) after a diagnosis of colorecta
26 n the relationship between cord levels of 25-hydroxyvitamin D (25[OH]D) and asthma and allergic disea
28 tation of less than 17 weeks, and a serum 25-hydroxyvitamin D (25[OH]D) concentration of 25-100 nmol/
29 exacerbation varied according to baseline 25-hydroxyvitamin D (25[OH]D) concentration, age, ethnic or
32 icovaginal HPV infection status and serum 25-hydroxyvitamin D (25[OH]D) level were known were studied
34 second trimesters of pregnancy and serum 25-hydroxyvitamin D (25[OH]D) levels in mothers during preg
35 aseline differences between patients with 25-hydroxyvitamin D (25[OH]D) levels less than 30 ng/mL vs
37 ograft recipients who had serum levels of 25-hydroxyvitamin D (25[OH]D) measured within the first 30
41 tide polymorphisms (SNPs) associated with 25-hydroxyvitamin D (25OHD) level from SUNLIGHT, the larges
42 24[A]), which conferred a large effect on 25-hydroxyvitamin D (25OHD) levels (-0.43 SD of standardize
43 an der Pols et al. observed that baseline 25-hydroxyvitamin D (25OHD) levels above 75 nmol/L were ass
44 morphisms (SNPs) strongly associated with 25-hydroxyvitamin D (25OHD) levels in 33,996 individuals, w
45 -nucleotide polymorphisms associated with 25-hydroxyvitamin D (25OHD) levels in the SUNLIGHT consorti
46 te a serum biomarker of vitamin D status, 25-hydroxyvitamin D (25OHD) measured at the time of breast
49 l deficiency of the Cyp27b1 gene encoding 25-hydroxyvitamin D 1-alpha-hydroxylase, which produces 1,2
50 in D receptor (rs4334089, rs11568820) and 25-hydroxyvitamin D 1alpha-hydroxylase (CYP27B1: rs4646536)
51 endritic cells, engineered to overexpress 25-hydroxyvitamin D 1alpha-hydroxylase and pulsed with a my
53 ation with DCs, engineered to overexpress 25-hydroxyvitamin D 1alpha-hydroxylase for de novo synthesi
54 imum concentration of vitamin D3 or serum 25-hydroxyvitamin D [25(OH)D3] lawfully allowed in feed) on
55 ations of the vitamin D hormone precursor 25-hydroxyvitamin D [25(OH)D3]; the high male prevalence of
56 t/obese women (50-75 y of age) with serum 25-hydroxyvitamin D [25(OH)D] >/=10 ng/mL but <32 ng/mL wer
58 investigated associations between plasma 25-hydroxyvitamin D [25(OH)D] (collected 1997 to 2000) and
59 nvestigate the relationship between serum 25-hydroxyvitamin D [25(OH)D] and incidence of allergic rhi
61 implications for the regulation of serum 25-hydroxyvitamin D [25(OH)D] and its catabolism and, conse
62 t increased circulating concentrations of 25-hydroxyvitamin D [25(OH)D] are associated with improved
63 s and to study associations between serum 25-hydroxyvitamin D [25(OH)D] at different developmental st
65 overweight or obese, vitamin D-deficient (25-hydroxyvitamin D [25(OH)D] concentration </=50 nmol/L) a
66 Vitamin D deficiency, defined as a serum 25-hydroxyvitamin D [25(OH)D] concentration <20 ng/mL, is c
67 pulation has poor vitamin D status (serum 25-hydroxyvitamin D [25(OH)D] concentration <25 nmol/L), pa
68 ts (74%) were vitamin D deficient (plasma 25-hydroxyvitamin D [25(OH)D] concentration <50 nmol/L).
69 e, but its efficacy in maintaining infant 25-hydroxyvitamin D [25(OH)D] concentration after birth is
70 e examined the association between plasma 25-hydroxyvitamin D [25(OH)D] concentration and islet autoi
72 ided for a mean of 8.1 d increased plasma 25-hydroxyvitamin D [25(OH)D] concentrations (P < 0.0001),
73 ed the prospective relation between serum 25-hydroxyvitamin D [25(OH)D] concentrations [which compris
74 amin D intakes required to maintain serum 25-hydroxyvitamin D [25(OH)D] concentrations above proposed
75 intakes required to maintain winter serum 25-hydroxyvitamin D [25(OH)D] concentrations above the prop
76 evious findings of an association between 25-hydroxyvitamin D [25(OH)D] concentrations and periodonta
78 the association between prehospital serum 25-hydroxyvitamin D [25(OH)D] concentrations and risk of HA
79 mined the association between circulating 25-hydroxyvitamin D [25(OH)D] concentrations and the outcom
80 ought to evaluate whether deficient serum 25 hydroxyvitamin D [25(OH)D] concentrations are associated
81 th hepatitis C virus (HCV) monoinfection, 25-hydroxyvitamin D [25(OH)D] concentrations are positively
82 rsy exists over the disparate circulating 25-hydroxyvitamin D [25(OH)D] concentrations between black
86 his study was to examine whether maternal 25-hydroxyvitamin D [25(OH)D] concentrations in pregnancy a
87 vely study the association between plasma 25-hydroxyvitamin D [25(OH)D] concentrations, vitamin D-rel
91 en described as being pandemic, but serum 25-hydroxyvitamin D [25(OH)D] distribution data for the Eur
92 er, so far, it is not clear whether serum 25-hydroxyvitamin D [25(OH)D] exerts any beneficial effect
94 ies have suggested that lower circulating 25-hydroxyvitamin D [25(OH)D] in African Americans may part
95 al evidence supports a protective role of 25-hydroxyvitamin D [25(OH)D] in breast carcinogenesis, but
97 clinical significance of low circulating 25-hydroxyvitamin D [25(OH)D] in obese people are unknown.
100 Epidemiologic data suggest that low serum 25-hydroxyvitamin D [25(OH)D] increases insulin resistance
105 ed the association between baseline serum 25-hydroxyvitamin D [25(OH)D] levels, supplemental vitamin
107 ciation between prediagnostic circulating 25-hydroxyvitamin D [25(OH)D] serum levels and the risk of
108 ed and reference values for the following 25-hydroxyvitamin D [25(OH)D] species: 25(OH)D2, 25(OH)D3,
109 ionship between body mass index (BMI) and 25-hydroxyvitamin D [25(OH)D] using genetic markers as inst
113 oratory models, the association of plasma 25-hydroxyvitamin D [25(OH)D] with patient survival is larg
114 d the risk of dementia.We measured plasma 25-hydroxyvitamin D [25(OH)D] with the use of high-performa
115 amin D) and 25-hydroxivitamin D2 plus D3 (25-hydroxyvitamin D [25(OH)D]) in foremilk and hindmilk dur
116 al long bone length, placental VDR, serum 25-hydroxyvitamin D [25(OH)D], 1,25-dihydroxyvitamin D [1,2
117 e evaluated the association between serum 25-hydroxyvitamin D [25(OH)D], a marker of vitamin D status
118 takes, fasting serum parathyroid hormone, 25-hydroxyvitamin D [25(OH)D], and ionized calcium were com
119 of vitamin D, or concentrations of serum 25-hydroxyvitamin D [25(OH)D], no longer increase calcium a
120 g and maintaining serum concentrations of 25-hydroxyvitamin D [25(OH)D], particularly at lower doses
123 ge and both BMI z score (zBMI) and venous 25-hydroxyvitamin D [25(OH)D]; the secondary objective was
125 ldren >4 y of age attain sufficient serum 25-hydroxyvitamin D [S-25(OH)D; i.e., >/=50 nmol/L] during
126 us in Finland between 2000 and 2011.Serum 25-hydroxyvitamin D [S-25(OH)D] concentrations of a nationa
130 pplementation rapidly and safely improves 25-hydroxyvitamin D and bioavailable 25-hydroxyvitamin D le
131 evidence of association between change in 25-hydroxyvitamin D and change in 24-hour systolic blood pr
132 id not indicate that associations between 25-hydroxyvitamin D and features of skin aging are causal.
133 This study investigated whether lower 25-hydroxyvitamin D and higher parathyroid hormone concentr
135 elation was observed between bioavailable 25-hydroxyvitamin D and LL-37 (Spearman rho = 0.44; p = 0.0
138 s) and 95% confidence intervals (CIs) for 25-hydroxyvitamin D and parathyroid hormone concentrations
139 teraction between serum concentrations of 25-hydroxyvitamin D and s-retinol on hip fracture was obser
142 othesis that low plasma concentrations of 25-hydroxyvitamin D are associated with increased risk of s
143 y age with changes in adiposity and serum 25-hydroxyvitamin D as primary or secondary outcomes were c
147 In contrast, a genetically determined 25-hydroxyvitamin D concentration was not associated with a
148 In addition, vitamin D inadequacy (serum 25-hydroxyvitamin D concentration, averaged across pregnanc
150 The intervention elevated 8-week serum 25-hydroxyvitamin D concentrations (154.5 nmol/L vs. 15.2 n
152 her there are causal associations between 25-hydroxyvitamin D concentrations and features of skin agi
153 n model comparing individuals with plasma 25-hydroxyvitamin D concentrations between the 1st and 4th
154 t and 4th percentiles to individuals with 25-hydroxyvitamin D concentrations between the 50th and 100
155 pplementation resulted in increased serum 25-hydroxyvitamin D concentrations compared with placebo (+
156 ation in participants with baseline serum 25-hydroxyvitamin D concentrations of less than 50 nmol/L (
162 mparing lowest versus highest quartile of 25-hydroxyvitamin D concentrations, the multivariate adjust
164 -diagnosed sepsis (n = 444), preadmission 25-hydroxyvitamin D deficiency is a significant predictor f
167 IU vitamin D2) increased serum levels of 25D-hydroxyvitamin D from 27+/-2 ng/ml before supplementatio
169 parathyroid hormone (PTH), phosphate, and 25-hydroxyvitamin D in a subset of 420 participants followe
174 in adults the associations between serum 25-hydroxyvitamin D level and prevalent asthma as well as a
175 amin D supplementation and milk intake on 25-hydroxyvitamin D level appeared similar regardless of sk
177 supplementation and cow's milk, increased 25-hydroxyvitamin D level by 3.4 ng/mL (95% CI, 2-4 ng/mL)
178 al older women with a mean baseline serum 25-hydroxyvitamin D level of 32.8 ng/mL, supplementation wi
179 ients with symptomatic asthma and a serum 25-hydroxyvitamin D level of less than 30 ng/mL was conduct
180 Vitamin D supplementation, but not serum 25-hydroxyvitamin D level or milk intake, was associated wi
182 65.2 years [SD, 7.0]; mean baseline serum 25-hydroxyvitamin D level, 32.8 ng/mL [SD, 10.5]), 2064 (90
184 0 years of age with low vitamin D status (25-hydroxyvitamin D levels </=25 ng/mL) and systolic blood
185 ogical studies support a link between low 25-hydroxyvitamin D levels and a higher risk of viral upper
188 ICU stay, the percentage of patients with 25-hydroxyvitamin D levels higher than 30 ng/mL at day 7, h
189 rrelation of shorter telomeres with lower 25-hydroxyvitamin D levels in both patients and controls.
190 oves 25-hydroxyvitamin D and bioavailable 25-hydroxyvitamin D levels in patients with severe sepsis o
192 lood levels were checked, 289 (74.9%) had 25-hydroxyvitamin D levels of 30 ng/mL or higher by the thi
194 itamin D had a mean net increase in serum 25-hydroxyvitamin D levels of 7.83 ng per milliliter, relat
195 p=0.021), but not in those with baseline 25-hydroxyvitamin D levels of at least 50 nmol/L (1.45, 0.8
197 ealth behaviors, and comorbid conditions, 25-hydroxyvitamin D levels under 20 ng/mL remained independ
202 BMD by dual-energy x-ray absorptiometry, 25-hydroxyvitamin D levels, and other laboratory assessment
203 tomatic knee osteoarthritis and low serum 25-hydroxyvitamin D levels, vitamin D supplementation, comp
205 sociation between obesity and lower serum 25-hydroxyvitamin D may be due to reversed causation with i
206 ndings: Initial evaluation should include 25-hydroxyvitamin D measurement, 24-hour urine calcium meas
207 (24R),25(OH)2D3) is a major catabolite of 25-hydroxyvitamin D metabolism and is an important vitamin
208 ld, contrasting the stimulatory effect of 25-hydroxyvitamin D or 1,25-dihydroxyvitamin D on related a
209 hepatocytes or monocytes with prohormone 25-hydroxyvitamin D or active 1,25-dihydroxyvitamin D decre
210 n was found between BMD and current serum 25-hydroxyvitamin D or dietary intake of calcium, protein,
212 whites had similar levels of bioavailable 25-hydroxyvitamin D overall (2.9+/-0.1 ng per milliliter an
213 r 2 years at a dose sufficient to elevate 25-hydroxyvitamin D plasma levels to higher than 36 ng/mL,
215 In chromatin immunoprecipitation assays, 25-hydroxyvitamin D promoted binding of the vitamin D recep
216 There was no association between neonatal 25-hydroxyvitamin D quintile and risk of multiple sclerosis
218 zed in the liver through hydroxylation to 25-hydroxyvitamin D species, and then further hydroxylated
223 tamin D, local osteoblastic conversion of 25-hydroxyvitamin D to 1,25-dihydroxyvitamin D appears to b
224 .6-fold higher in those with preadmission 25-hydroxyvitamin D values in the insufficient and deficien
225 line, median (interquartile range) plasma 25-hydroxyvitamin D was 17 ng/mL (13-22 ng/mL) and peaked b
227 wo cohorts, we observed that higher serum 25-hydroxyvitamin D was associated with a higher perceived
229 tography-tandem mass spectrometry method, 25-hydroxyvitamin D was measured in stored baseline serum s
230 patients, 18 years old or older, in whom 25-hydroxyvitamin D was measured prior to hospitalization b
231 dicted the three clinical outcomes; total 25-hydroxyvitamin D was not inferior to the other measures.
233 olecalciferol-treated patients, change in 25-hydroxyvitamin D was strongly correlated with change in
234 Serum concentrations of vitamin A and 25-hydroxyvitamin D were significantly reduced after duoden
235 e resulted in a greater increase in serum 25-hydroxyvitamin D with a mean difference of 3.11 nmol/L (
236 tes, demonstrated an association of total 25-hydroxyvitamin D with hospital length of stay (incident
237 udy and found that the association of low 25-hydroxyvitamin D with increased secondary CVD event risk
238 emained significant associations of total 25-hydroxyvitamin D with readmission (odds ratio per 1 ng/m
239 he link between season of birth, neonatal 25-hydroxyvitamin D(3) [25(OH)D(3)] status, and adult cardi
240 N-terminal pro-brain natriuretic peptide, 25-hydroxyvitamin D) and 2 nonhormones (prostate-specific a
241 and high circulating levels of calcidiol (25-hydroxyvitamin D) each increased serum FGF23 levels in w
242 arkers (parathyroid hormone, calcium, and 25-hydroxyvitamin D), and annualized BMD reduction over a 8
243 , respectively, were as follows: 1) total 25-hydroxyvitamin D, 3% (-3% to 8%), 49% (30-82%), and 69%
244 9% (55-106%) (p < 0.001); 2) bioavailable 25-hydroxyvitamin D, 4% (-8% to 7%), 45% (40-70%), and 96%
245 en parathyroid hormone (PTH), circulating 25-hydroxyvitamin D, and markers of mineral metabolism and
246 and on days 3, 5, and 7, to assess total 25-hydroxyvitamin D, as well as vitamin D-binding protein a
247 per week, exercise per week, and current 25-hydroxyvitamin D, higher neonatal 25(OH)D(3) (per 50 nmo
248 he addition of serum calcium, phosphorus, 25-hydroxyvitamin D, intact parathyroid hormone, and 24,25-
249 ect of high circulating concentrations of 25-hydroxyvitamin D, local osteoblastic conversion of 25-hy
250 iomarkers on the metabolic pathway (e.g., 25-hydroxyvitamin D, parathyroid hormone, phosphorus) had l
252 birth, breastfeeding) and in adult life (25-hydroxyvitamin D, sun exposure, vitamin D intake from da
253 idney stones was not modified by baseline 25-hydroxyvitamin D, vitamin D dose and duration, or calciu
254 ifiable biological factor downstream from 25-hydroxyvitamin D, was responsible for the majority of th
255 nt mast cell activation through mast cell-25-hydroxyvitamin D-1alpha-hydroxylase (CYP27B1) and mast c
263 ciated with lower concentrations of serum 25-hydroxyvitamin D; however, uncertainty exists as to the
264 /MS) method for measuring 25(OH)D (sum of 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3), calibrated
265 t-soluble vitamins all-trans retinol (A), 25-hydroxyvitamin D2, 25-hydroxyvitamin D3, alpha-tocophero
266 (LOD) for the low-concentration analytes (25-hydroxyvitamin D2, 25-hydroxyvitamin D3, and phylloquino
267 eficiency was defined as a serum level of 25-hydroxyvitamin D3 < 20 ng/mL (equivalent to < 50 nM) bef
269 , we used a case-cohort design to compare 25-hydroxyvitamin D3 (25(OH)D3 ) levels among infants with
271 fferent races and the association between 25-hydroxyvitamin D3 (25[OH]D) levels in pregnancy and the
272 nvestigated the association between serum 25-hydroxyvitamin D3 (25[OH]D3) levels and food allergy at
273 Three hundred fifty-nine pretreatment 25-hydroxyvitamin D3 (25[OH]D3) serum levels from the RICOV
274 precursor metabolite in the circulation, 25-hydroxyvitamin D3 (25OHD3), can influence IgE-mediated m
275 synthesize calcitriol from its precursor 25-hydroxyvitamin D3 (inactive precursor) [25(OH)D] upon an
276 nscription of Cyp24a1 encoding the enzyme 25-hydroxyvitamin D3 24-hydroxylase involved in the catabol
278 n skin cells that produce the noncalcemic 20-hydroxyvitamin D3 [20(OH)D3] and 20,23-dihydroxyvitamin
279 tion during childhood.We examined whether 25-hydroxyvitamin D3 [25(OH)D3] concentrations in stored ne
281 tion of target genes.In placental tissue, 25-hydroxyvitamin D3 [25(OH)D3] was strongly correlated (r
283 skin of female mice and normalized serum 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 levels, a
284 rds having more access to sunlight, while 25-hydroxyvitamin D3 concentration was higher (P<0.05) only
286 in D3 metabolism at all stages and plasma 25-hydroxyvitamin D3 depletion in the acute and latent phas
288 that only lifelong treatment raised serum 25-hydroxyvitamin D3 from 173 nmol/L in controls to 290 nmo
290 estigated the retention of vitamin D3 and 25-hydroxyvitamin D3 in eggs, vitamin D3 in margarine, and
292 had significantly lower concentrations of 25-hydroxyvitamin D3 than patients with either mild sepsis
294 25(OH)D (sum of 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3), calibrated to standard reference mat
295 -trans retinol (A), 25-hydroxyvitamin D2, 25-hydroxyvitamin D3, alpha-tocopherol (E), gamma-tocophero
296 king a 1alpha-hydroxyl group (vitamin D3, 25-hydroxyvitamin D3, and 24R,25-dihydroxyvitamin D3) decre
297 entration analytes (25-hydroxyvitamin D2, 25-hydroxyvitamin D3, and phylloquinone) were 25, 17, and 0
298 ), is synthesized by the essential enzyme 25-hydroxyvitamin D3-1alpha-hydroxylase (CYP27B1), which ca
299 ions in the vitamin D catabolizing enzyme 25-hydroxyvitamin D3-24-hydroxylase (CYP24A1) were describe
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