ライフサイエンスコーパス: hyperinflation

1 ong-acting muscarinic antagonists, to reduce hyperinflation.

2 activation were elevated in severe COPD and hyperinflation.

3 life for patients with severe emphysema and hyperinflation.

4 tment of patients with severe emphysema with hyperinflation.

5 ury when pneumonia/sepsis is coupled to lung hyperinflation.

6 strate prominent peribronchial markings with hyperinflation.

7 gical changes, especially the development of hyperinflation.

8 nd prolong exercise time by reducing dynamic hyperinflation.

9 ed with the degree of airflow limitation and hyperinflation.

10 o impaired diaphragm function resulting from hyperinflation.

11 low an estimation of the degree of pulmonary hyperinflation.

12 nd lung volumes showed a slight worsening in hyperinflation.

13 apping and differentiation from compensatory hyperinflation.

14 n atria and the diaphragm and, therefore, by hyperinflation.

15 iratory muscle function, and reduces dynamic hyperinflation.

16 s in patients with emphysema and severe lung hyperinflation.

17 ecrease) and severe (23% decrease) levels of hyperinflation.

18 /- 132 grams; P < 0.001) and increased tidal-hyperinflation (0.41 +/- 0.26 to 0.57 +/- 0.30%; P = 0.0

19 veloped native lung complications (excluding hyperinflation) 0-58 months (mean, 17 months) after tran

20 ssure levels were applied in a random order: hyperinflation, 6 cm H2O above; open lung approach, 2 cm

21 weakness but without airflow obstruction or hyperinflation, a group that would ideally define the ro

22 As a measure of significant hyperinflation, a vertical P axis had a sensitivity of 8

23 genic diet was injured by repetitive balloon hyperinflations, a procedure that rapidly yields complex

24 reversibility (P = 0.01), and improvement in hyperinflation after corticosteroid treatment (P = 0.019

25 We conclude that LVRS, by reducing hyperinflation, air trapping, and improving respiratory

26 by expiratory muscle contraction and dynamic hyperinflation, all increasing pulmonary vascular pressu

27 Hyperinflation alone did not produce tightness or effort

28 re must be taken to avoid augmenting dynamic hyperinflation and acid/base disturbances resulting from

29 elation to vital capacity and to markers for hyperinflation and airway obstruction were found in pati

30 trol subjects, there was significant dynamic hyperinflation and greater tidal volume constraints (P<0

31 tment of patients with emphysema with severe hyperinflation and less parenchymal destruction.

32 These included effects on lung hyperinflation and mechanical stress, inflammation, exce

33 rflow obstruction that leads to dynamic lung hyperinflation and reduced ventilatory response to exerc

34 pulmonary hypertension is induced by airway hyperinflation and supraphysiologic lung volumes.

35 constriction with subsequent effects on lung hyperinflation (and possibly pulmonary circulation) can

36 olume was increased to achieve 25% (moderate hyperinflation) and 50% (severe hyperinflation) incremen

37 ts were 57 +/- 8 yr of age with severe COPD, hyperinflation, and air trapping (FEV1, 0.73 +/- 0.2 L;

38 h of anesthesia and muscle rigidity, gastric hyperinflation, and alveolar collapse) require urgent re

39 d with reduced FEV1 to FVC ratio (FEV1/FVC), hyperinflation, and alveolar enlargement, but little is

40 a coalescence of mechanical forces, such as hyperinflation, and more recently recognized cellular an

41 1 s (FEV1) between 20% and 45%, substantial hyperinflation, and post-rehabilitation 6-min walk test

42 OPD are due to reduction of lung resistance, hyperinflation, and TGC.

43 t the hypothesis that airflow limitation and hyperinflation are associated with the duration of asthm

44 e of advanced emphysematous lung disease and hyperinflation are optimal candidates for lung-volume-re

45 Pulmonary hyperinflation, as measured by residual lung volume or r

46 ratory rate (i.e., less reduction in dynamic hyperinflation at a lower respiratory rate).

47 Patients exhibited less dynamic hyperinflation at isotime points with spinal anesthesia.

48 ed at baseline and after moderate and severe hyperinflation, both before and after nitric oxide admin

49 The animal model displayed hyperinflation (change in total lung capacity +8%; chang

50 Lower forced expiratory volume, PA:A>1, and hyperinflation correlated with reduced RV ejection fract

51 aluated the prevalence and impact of dynamic hyperinflation (DH) in LAM.

52 Dynamic hyperinflation (DH) is a major pathophysiologic conseque

53 BLVR aims to decrease the extent of hyperinflation due to emphysema and result in a benefici

54 In 12 patients we also quantified dynamic hyperinflation (end-expiratory and end-inspiratory lung

55 rves, along with regional recruitment versus hyperinflation evidence from computed tomography and ele

56 ere 58 +/- 8 yr of age, with severe COPD and hyperinflation (FEV1 = 0.68 +/- 0.23 L, FVC = 2.56 +/- 7

57 ere 58 +/- 8 yr of age, with severe COPD and hyperinflation (FEV1, 0.69 +/- 0.21 L; RV, 4.7 +/- 1.4 L

58 ons were observed between Tw Pdi and dynamic hyperinflation (FRC: r = -0.65, P = 0.005) and arterial

59 regions suffering tidal recruitment or tidal hyperinflation had [(18)F]fluoro-2-deoxy-D-glucose uptak

60 nd distal airways and may induce significant hyperinflation (HI).

61 itive end-expiratory pressure setting limits hyperinflation in acute lung injury, but may not provide

62 are palliative treatments aimed at reducing hyperinflation in advanced emphysema.

63 lator is highly sensitive and predictive for hyperinflation in children.

64 Pulmonary hyperinflation in chronic obstructive pulmonary disease

65 ngation of expiratory time decreases dynamic hyperinflation in patients with status asthmaticus, as e

66 ncluded in multivariate regression analysis, hyperinflation (increased thoracic gas volume) was the p

67 s of lung elastic recoil resulting in marked hyperinflation, increased TLC, and decreased Pdi and exp

68 5% (moderate hyperinflation) and 50% (severe hyperinflation) increments in pulmonary vascular resista

69 oxide at baseline (43% decrease) and during hyperinflation induced pulmonary hypertension at both mo

70 ameliorated experimental ventilator-induced hyperinflation lung injury as determined by pulmonary ca

71 in severe asthma, and that marked pulmonary hyperinflation may be present despite low measured auto-

72 s, although reduction of lung resistance and hyperinflation may result in improved dyspnea with a bro

73 ss to end-diastolic volume (P=0.02) and with hyperinflation measured as residual volume to total lung

74 ty that effects of LABA/LAMA combinations on hyperinflation, mucociliary clearance, and symptom sever

75 1 was prominent peribronchial markings with hyperinflation (n = 17), whereas the most common finding

76 In patients with compensatory hyperinflation (n = 4), mean lung attenuation was -664 H

77 tment and decreases alveolar instability and hyperinflation observed at high PEEP in patients with AR

78 +/- 141 grams; P = 0.028) and reduced tidal hyperinflation observed at PEEP 15 in supine patients (0

79 d at the prealveolar stage with compensatory hyperinflation of immature saccules.

80 y obstruction secondary to emphysema, marked hyperinflation of the chest wall, and regional heterogen

81 were elevated in severe COPD (P = 0.003) and hyperinflation (P = 0.001).

82 l [CI]: 0.21, 0.91), residual volume (static hyperinflation, r = -0.8; 95% CI: -0.94, 0.42), and forc

83 We recruited 315 patients who had severe hyperinflation (ratio of residual volume [RV] to total l

84 xercise tolerance in patients with pulmonary hyperinflation related to advanced emphysema.

85 d, FEF(25-75%) 11.0 +/- 4.5% predicted), and hyperinflation (residual volume [RV] 341.8 +/- 75.8% pre

86 oughout expiration, the reduction in dynamic hyperinflation resulting from a given prolongation of ex

87 With the exception of dynamic hyperinflation states, it is reasonable to assume that n

88 e and for up to 3 h after repetitive balloon hyperinflations sufficient to disrupt the internal elast

89 Of 27 subjects with moderate or severe hyperinflation (TGV > or = 130% predicted), 23 (85%) had

90 The hyperinflation that accompanies diseases of the airways

91 ay not always reflect the changes in dynamic hyperinflation that result from prolongation of expirato

92 EV1) of less than 50% predicted, significant hyperinflation (total lung capacity >100% and residual v

93 Despite hyperinflation, transdiaphragmatic pressures and strengt

94 Among patients with emphysema and severe hyperinflation treated for 12 months, the use of endobro

95 Hyperinflation was defined as residual volume/total lung

96 Hyperinflation was present at residual volume (RV), FRC,

97 Marked hyperinflation was present in all 10 patients studied, w

98 r blood flow (PMBF), diffusing capacity, and hyperinflation were also examined.

99 Cyclic recruitment/de-recruitment and tidal hyperinflation were determined as tidal changes in perce

100 Loss of lung elastic recoil causing hyperinflation with increased TLC and decreased diffusin