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1 clear separation of function by becoming DNA hypermutators.
2       Mucoid isolates were more likely to be hypermutators.
3 eds the fitness advantage, selecting against hypermutators.
4 d of transient hypermutation, and that these hypermutators account for the mutations that appear.
5      From these numbers we conclude that the hypermutators are responsible for nearly all multiple mu
6                                              Hypermutators arise through several mechanisms, includin
7 ronmental stresses may lead to selection for hypermutator bacterial cells, which have an increased ch
8        Finally, a subpopulation of transient hypermutators could be a source of multiple variant alle
9  of the effect of spontaneous mutations in a hypermutator (DeltamutS) strain of the bacterium Pseudom
10 P levels and (ii) this increase mediates the hypermutator effect of Poldelta-R696W by facilitating th
11  little evidence exists of stable eukaryotic hypermutators in nature.
12               However, the long-term fate of hypermutators is unknown.
13 draft genome sequence of a derived inducible hypermutator isolate differed from those of general hype
14            Our study identifies a eukaryotic hypermutator lineage spread over two continents and sugg
15 rted here investigated the contribution that hypermutators make to the mutations occurring in a Lac-
16 tions living in stable environments, whereas hypermutators may evolve if conditions change.
17 cur in 5-10% of sporadic CRCs and underlie a hypermutator, microsatellite-stable molecular phenotype.
18                        A dominant mucoid and hypermutator mutL lineage was replaced after 11 days by
19 nt mutant subpopulations was associated with hypermutator phenotype but was not good enough to be use
20                                            A hypermutator phenotype in two cases with >8 times higher
21 ia coli population that first evolved a mutT hypermutator phenotype was later invaded by two independ
22                   One outbreak isolate had a hypermutator phenotype with a higher number of SNPs than
23  including a mutation in mutS that confers a hypermutator phenotype.
24                              The presence of hypermutator Pseudomonas aeruginosa was associated with
25 tator isolate differed from those of general hypermutators reported in the literature.
26                                 Furthermore, hypermutator states are transitory and repeatedly altern
27                     The successful growth of hypermutator strains of bacteria contradicts a clear pre
28 e transient and do not involve selection for hypermutator strains.
29              Thus, the long-term fate of the hypermutators was governed by the selective advantage ar

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