ライフサイエンスコーパス: hyperosmolar

1 Many sexual lubricants are hyperosmolar.

2 lity further revealed lymphoid tissues to be hyperosmolar.

3 Because acetic acid is hyperosmolar, a second aim was to determine if the osmol

4 er, current treatment options are limited to hyperosmolar agents and surgical decompression, therapie

5 We apply these results to the hyperosmolar and pheromone mitogen-activated protein (MA

6 ylene glycol accumulation, as reflected by a hyperosmolar anion gap metabolic acidosis, was observed

7 lymerizing agent latrunculin B abrogated the hyperosmolar barrier enhancement as well as the actin fi

8 We examined the effect of hyperosmolar BBB disruption on brain permeability of thr

9 hese findings indicate that in EC exposed to hyperosmolar challenge, the involvement of focal adhesio

10 After a hyperosmolar challenge, there was markedly reduced expre

11 ministered directly into the renal artery in hyperosmolar citrate solution (3 mug/ml) with the renal

12 pound120 per liter) and Marshall's Solution (hyperosmolar citrate, pound10 per liter).

13 10-min warm ischemia and flushed with 500 mL hyperosmolar citrate.

14 sttransplant diabetes included ketoacidosis, hyperosmolar coma or precoma, and sensorimotor periphera

15 ed (3.5-fold) when the cells were exposed to hyperosmolar conditions (DMEM-F12 culture medium plus 50

16 s to provide indirect evidence of short-term hyperosmolar conditions during tear instability and to t

17 n-Hep complexes, which was inhibited >70% by hyperosmolar conditions, confirming that uptake is media

18 ent growth and resist PCD due to hypoxia and hyperosmolar conditions.

19 ein levels increased in RPE cells exposed to hyperosmolar conditions.

20 ns and increased by approximately twofold in hyperosmolar conditions.

21 etT3 was the major choline transporter under hyperosmolar conditions.

22 nse to growth factors, oxidative stress, and hyperosmolar conditions.

23 r protein Shc in lysates of RLMEC exposed to hyperosmolar conditions.

24 neuronal survival is not enhanced by chronic hyperosmolar conditions.

25 transiently stressed with the same range of hyperosmolar culture medium, and proinflammatory mitogen

26 sham, 2) HS + CR, and 3) HS + CR + PR with a hyperosmolar dextrose-based solution (Delflex 2.5%).

27 e data suggest that the clinical efficacy of hyperosmolar disruption therapy in conjunction with chem

28 Survival after transplantation using hyperosmolar donors was not affected in this study.

29 tions after instillation of NaCl and sucrose hyperosmolar drops (300-1000 mOsM/kg).

30 Hyperosmolar enemas induce epithelial damage, and enema

31 vation of cell viability and function in the hyperosmolar environment of the renal medulla is a compl

32 Hyperosmolar exposure also increased activity of focal a

33 The dominant effect of a 15-min hyperosmolar exposure was an increase in the trans-endot

34 Barrier recovery after a 1-min hyperosmolar exposure was delayed > 25 min.

35 tive isoforms of Rac1, the actin response to hyperosmolar exposure was enhanced or blocked, respectiv

36 n flux reversal from isosmolar absorption to hyperosmolar filtration (P < 0.01), and by hyperosmolari

37 specific treatments (e.g., administration of hyperosmolar fluids and the use of hyperventilation) in

38 y measured through 12 h was reduced with the hyperosmolar gel (P=.037).

39 e anus occurred to a greater degree with the hyperosmolar gel than with the iso-osmolar formulation (

40 The hyperosmolar gel was also associated with lower isotope

41 Rectally applied hyperosmolar gels induce greater epithelial denudation a

42 ibly increases the risk of HIV transmission, hyperosmolar gels make poor rectal microbicide formulati

43 ide formulation, we evaluated the effects of hyperosmolar gels on the rectal mucosa.

44 ne green uptake was markedly impaired in the hyperosmolar group, suggesting that hepatocyte and not s

45 infusing small, non-adhesive NP via CED in a hyperosmolar infusate solution.

46 Furthermore, hyperosmolar infusion blocked TNF-alpha-induced P-select

47 illary immunofluorescence indicated that the hyperosmolar infusion markedly augmented actin filament

48 ial cells freshly harvested from lungs given hyperosmolar infusions indicated a genistein-inhibitable

49 larity and tear instability, suggesting that hyperosmolar levels in the tear film may transiently spi

50 barrier has been disrupted by exposure to a hyperosmolar mannitol solution, permitting the translumi

51 ld be enhanced by intrathecal co-infusion of hyperosmolar mannitol.

52 t brain after intracarotid administration of hyperosmolar mannitol.

53 auT reporter activity in isotonic as well as hyperosmolar media.

54 and peaked at 60 minutes in cells exposed to hyperosmolar media.

55 A and protein levels in the cells exposed to hyperosmolar media.

56 Exposure of PCHCE cells to hyperosmolar medium increased TG activity at 3 hours, le

57 the wild-type and the phgA mutant strains in hyperosmolar medium, and when analyzed by electron micro

58 ptake occurred after 17 hours of exposure to hyperosmolar medium.

59 eath-inducing paradigms: mitogen withdrawal, hyperosmolar metabolic stress, and treatment with etopos

60 ricants were compounded into iso-osmolar and hyperosmolar mixtures (283 and 3429 mOsm/kg, respectivel

61 , 30 responded to intraduodenal perfusion of hyperosmolar NaCl (500 mosmol l(-1)), 27 responded to ta

62 to intraduodenal administration of maltose, hyperosmolar NaCl, and light mucosal stroking were exami

63 pancreatic secretion induced by maltose and hyperosmolar NaCl.

64 Patients with diabetic ketoacidosis or hyperosmolar nonketotic coma were excluded.

65 tract, and by inference the development of a hyperosmolar periciliary fluid, do not appear to be the

66 Hyperosmolar PR during CR maintains intestinal blood flo

67 Hyperosmolar pretreatment also blocked the acid-induced

68 microscopy of liver biopsies collected from hyperosmolar rats demonstrated profound ultrastructural

69 Cold-preserved livers from hyperosmolar rats were observed to have elevated hepatic

70 n the lung, salivary, and lacrimal glands of hyperosmolar rats, suggesting potential physiologic rele

71 n cells in kidney and brain are exposed to a hyperosmolar salt condition (hypertonicity) due to the o

72 ke poor rectal microbicide formulations, and hyperosmolar sexual lubricants may increase susceptibili

73 muscle contraction, and sorbitol (producing hyperosmolar shock) did not increase AMPK alpha2 activit

74 stigated: co-infusion of nanoparticles and a hyperosmolar solution of mannitol, and pre-infusion of a

75 -51 degrees C), menthol (10-100 microM), and hyperosmolar solutions (NaCl, sucrose; 297-3014 mOsm), a

76 These sensations also occurred with hyperosmolar solutions (thresholds, 450-460 mOsM/kg) tha

77 Clinically, infusion of hyperosmolar solutions is used to enhance chemotherapeut

78 This is thought to be a direct effect of hyperosmolar solutions on the visceral microvessels.

79 us (progesterone) and a pathological stress (hyperosmolar sorbitol) in Xenopus laevis oocytes, a cell

80 ncreased more than twofold after exposure to hyperosmolar sorbitol.

81 of hypotonic stress is distinct from that of hyperosmolar stress in mammalian cells.

82 Hyperosmolar stress is not a necessary determinant of AR

83 the corneal epithelium responds to transient hyperosmolar stress.

84 PK was activated at 600 mOsM/kg of transient hyperosmolar stress.

85 mperature or in the presence of cell wall or hyperosmolar stresses.

86 However, a 15-min intravenous infusion of hyperosmolar sucrose given up to 1 h before or 30 min af

87 ble strategy, we gave 15-minute infusions of hyperosmolar sucrose in lung venular capillaries imaged

88 The potential applicability of hyperosmolar sucrose in therapy for ALI requires conside

89 he extent to which intravascular infusion of hyperosmolar sucrose might protect against acid-induced

90 We infused hyperosmolar sucrose via the femoral vein.

91 ungs indicated that the protective effect of hyperosmolar sucrose was leukocyte independent.

92 howed that a brief intravascular infusion of hyperosmolar sucrose, given concurrently with airway aci

93 of the corneal epithelium in response to the hyperosmolar tear film in dry eye disease.

94 arameters describing water movement into the hyperosmolar tear film in vivo--were determined by a dye

95 trinsic factors that promote an unstable and hyperosmolar tear film.

96 oration of tears from the ocular surface and hyperosmolar tears.

97 Using isosmolar and hyperosmolar test solutions (colloid osmotic pressure =

98 pv4-/- mice drank less water and became more hyperosmolar than did wild-type littermates, a finding t

99 To consider hyperosmolar therapy as a possible strategy, we gave 15-

100 Hyperosmolar therapy may be beneficial in lung inflammat

101 In this study, we report that hyperosmolar treatment mediates FAK dephosphorylation an