ライフサイエンスコーパス: hyperpigmentation

1 nocyte regeneration as well as skin and hair hyperpigmentation.

2 e, implicating keratinocytes in the aberrant hyperpigmentation.

3 e typical CALMs that appear over the general hyperpigmentation.

4 rmal melanocytes, resulting in skin and hair hyperpigmentation.

5 ular pressure going along with chamber angle hyperpigmentation.

6 AG lasers gave excellent results in gingival hyperpigmentation.

7 mines metformin as a potential drug to treat hyperpigmentation.

8 All patients experienced diffuse hyperpigmentation.

9 s who were included, 16 (21%) presented with hyperpigmentation.

10 h SD-OCT in eyes with larger drusen and with hyperpigmentation.

11 signaling and in turn leads to skin and hair hyperpigmentation.

12 roducts for skin lightening and treatment of hyperpigmentation.

13 differences account completely for lesional hyperpigmentation.

14 laucoma, selected to have clinically visible hyperpigmentation.

15 emperature, high water evaporation rate, and hyperpigmentation.

16 Nearly all patients with FES showed eyelid hyperpigmentation.

17 ally significant alopecia (30%), periorbital hyperpigmentation (30%), deep rhytides on the face (20%)

18 ng eyes with undiagnosed AMD, 32 (10.0%) had hyperpigmentation, 43 (13.4%) had hypopigmentation, 249

19 < .001), breast pain (55% vs 74%; P = .001), hyperpigmentation (9% vs 20%; P = .002), and fatigue (9%

20 low-up, and 2 withdrew owing to inflammatory hyperpigmentation after the laser treatment.

21 its several characteristics of DC, including hyperpigmentation and fatal bone marrow failure at 4-5 m

22 ts novel evidence for a relationship between hyperpigmentation and increased superoxide-generating ca

23 sities, large painful varicose veins, edema, hyperpigmentation and lipodermatosclerosis of skin, and

24 aracterized by cutaneous symptoms, including hyperpigmentation and nail dystrophy.

25 0E) mutation) led to the development of skin hyperpigmentation and nevi, as well as melanoma formatio

26 Transient discrete residual hyperpigmentation and scaling were present.

27 val intraepithelial melanin overproduction ("hyperpigmentation") and intraepithelial melanocytic prol

28 toderma, hypodontia, enamel hypoplasia, oral hyperpigmentation, and dysphagia.

29 ctive ORs for the presence of a large druse, hyperpigmentation, and fellow eye affected were 2.60, 1.

30 area, presence of one or five large drusen, hyperpigmentation, and fellow eye status was calculated.

31 ndrome characterized by bone marrow failure, hyperpigmentation, and nail dystrophy.

32 ging other than rhytids, such as lentigines, hyperpigmentation, and telangiectasias, should be consid

33 fe-au-lait" macules (CALMs) and overall skin hyperpigmentation are early hallmarks of neurofibromatos

34 ncentrations, right upper quadrant pain, and hyperpigmentation are often substantially alleviated by

35 The data support hyperpigmentation as a protective antioxidant mechanism

36 s might be useful for the correction of skin hyperpigmentation as a side-effect of chemotherapy.

37 Five subjects developed areas of persistent hyperpigmentation at r-hSCF injection sites; by light mi

38 accumulations of mast cells in the skin and hyperpigmentation at sites of chronic cutaneous inflamma

39 For postinflammatory hyperpigmentation, azelaic acid holds promise.

40 epithelium (RPE) depigmentation (34.9%), RPE hyperpigmentation (branching reticular pigmentation) (22

41 wounds, beta2ARag reduced both scar area and hyperpigmentation by almost 50% and significantly improv

42 ethod, subretinal tissues such as those with hyperpigmentation can be visualized with increased contr

43 Although pathways underlying hyperpigmentation cascade are recognized, negative feedb

44 Hyperpigmentation disorders are generally difficult to t

45 nin biosynthesis, is closely associated with hyperpigmentation disorders, cancer, and neurodegenerati

46 ctive skin-lightening products to treat skin hyperpigmentation disorders, including postinflammatory

47 suggest that metformin may be used to treat hyperpigmentation disorders.

48 meceutical" skin lightening and treatment of hyperpigmentation disorders.

49 Secondary hyperpigmentation during interferon alfa treatment occur

50 Cases of cutaneous and mucous hyperpigmentations during interferon alfa treatment have

51 and other lesions associated with cutaneous hyperpigmentation, extracardiac myxomas, and nonmyxomato

52 ost common cutaneous reactions are alopecia, hyperpigmentation, hand--foot syndrome, radiation recall

53 were defined using a scoring system based on hyperpigmentation, hardening, and tethering of skin on t

54 In intermediate AMD, macular hyperpigmentation has high spatial correlation to SDOCT

55 Hyperpigmentation, hyperkeratoses, and Bowen's disease a

56 de H syndrome, characterized by scleroderma, hyperpigmentation, hypertrichosis, hepatomegaly, cardiac

57 Among them, 29 eyes had early AMD (drusen, hyperpigmentation, hypopigmentation), 5 had extrafoveal

58 rosinase inhibitors for suppressing unwanted hyperpigmentation in human skin and enzymic browning in

59 t hemocyanin may act as a causative agent of hyperpigmentation in N. norvegicus.

60 luding peculiar caudal fin malformations and hyperpigmentation in the tail, were measured in several

61 Drusen size, distribution, drusen area, and hyperpigmentation in two central macular regions on base

62 ptosis in the intestinal crypt and epidermal hyperpigmentation indicate the presence of elevated geno

63 Cutaneous hyperpigmentation is a common disorder due to excess mel

64 Macular hyperpigmentation is associated with progression from in

65 AG) and diode, for the treatment of gingival hyperpigmentation is compared.

66 Hyperpigmentation is observed in the interfollicular epi

67 s colocalization with large, soft drusen and hyperpigmentation is several times greater than chance,

68 The phenomenon of hyperpigmentation (melanosis) in shellfish has long been

69 tation disorders, including postinflammatory hyperpigmentation, melasma and solar lentigines.

70 F ) function contribute to scarring, whereas hyperpigmentation negatively affects scar quality.

71 nmyelopathy accompanied by short stature and hyperpigmentation, now better known as Fanconi anemia (F

72 In the distal limb, there were agenesis and hyperpigmentation of claws, interdigital webbing, reduce

73 syndromes that include benign neurofibromas, hyperpigmentation of melanocytes and hamartomas of the i

74 ane, acquired longitudinal melononychia, and hyperpigmentation of the face were each observed in 7 pa

75 Most patients with hyperpigmentation of the oral mucosa also had melanonych

76 Hyperpigmentation of the oral mucous membrane, acquired

77 Hyperpigmentation of the pinnae and tail could be detect

78 Hyperpigmentation of the retinal pigment epithelium was

79 membrane, and atrophy, hypopigmentation, and hyperpigmentation of the retinal pigment epithelium.

80 However, patients with hyperpigmentation of the skin did not have mucosal or na

81 All patients with hyperpigmentation of the skin had skin type III or IV an

82 in the central nervous system, and patterned hyperpigmentation of the skin.

83 pigmentation (OR, 9.0; 95% CI, 4.1-19.8); or hyperpigmentation (OR, 12.0; 95% CI, 6.1-23.5), referenc

84 events (including erythema, rash, pruritus, hyperpigmentation, pain, hypopigmentation, and oedema) o

85 isual acuity, bull's eye maculopathy, foveal hyperpigmentation, peripapillary atrophy, dyschromatopsi

86 Vaccine-induced hyperpigmentation persisted for at least 180 days after

87 Finally, the hyperpigmentation phenotype can be rescued using specifi

88 monstrate that NF1 melanocytes reproduce the hyperpigmentation phenotype in vitro, and further charac

89 3 transgene is important to the onset of the hyperpigmentation phenotype.

90 t as a treatment option for postinflammatory hyperpigmentation (PIH) but can pose a clinical dilemma

91 t as a treatment option for postinflammatory hyperpigmentation (PIH) but can pose a clinical dilemma

92 V-sensitivity syndrome characterized by skin hyperpigmentation, premature aging, and increased skin c

93 orescence analysis demonstrated pathological hyperpigmentation, proliferation and hyperplasia of acti

94 onditions (alopecia, allergic skin diseases, hyperpigmentation, psoriasis, skin cancer, pachyonychia

95 ations have been reported to cause cutaneous hyperpigmentation resembling that of alkaptonuria.

96 ivity, converting Fe(3+) to Fe(2+), but that hyperpigmentation results in excessive reduction of iron

97 Regions of hyperpigmentation, selected using stereo color fundus ph

98 Minocycline-induced hyperpigmentation should be considered in the differenti

99 cognized lack of attached gingiva, pretibial hyperpigmentation, skin and vascular fragility, easy bru

100 succinate dehydrogenase subunit A alongside hyperpigmentation suggested coregulation of activity and

101 Transient hyperpigmentation, superficial exfoliation, and crusting

102 ult Krt9(-/-)mice develop calluses marked by hyperpigmentation that are exclusively localized to the

103 The number of participants diagnosed with hyperpigmentation was 673; with hyperkeratosis, 243; and

104 s occurred in eight of 22 patients (36%) and hyperpigmentation was noted in 12 of 22 patients (55%),

105 Macular CFP hyperpigmentation was significantly associated with SDOC

106 s, 28 of 39 (71.8%) retinal CFP regions with hyperpigmentation were correlated with focal hyperreflec

107 uiring treatment for mild-to-severe gingival hyperpigmentation were enrolled.

108 Measurements on versus off hyperpigmentation were made in nine persons with suspect

109 resence of large drusen, and the presence of hyperpigmentation were not consistent risk factors for a

110 ites from 35 patients with bilateral melanin hyperpigmentation were treated with surgical stripping (

111 the reproductive abnormalities but not skin hyperpigmentation, whereas deletion of cell cycle arrest

112 e or nonfibrotic with discrete flat areas of hyperpigmentation with varying amounts of central depigm

113 h fractionated CO2 for her scarring, but her hyperpigmentation worsened with each treatment.