ライフサイエンスコーパス: hypnotic

1 in reuptake inhibitors) and 27.4% a sedative/hypnotic.

2 e sedation and serve as targets for sedative hypnotics.

3 the majority of clinically relevant sedative-hypnotics.

4 icidal" with each of the modern FDA-approved hypnotics.

5 er flies, and is modulated by stimulants and hypnotics.

6 idely used anxiolytics, anticonvulsants, and hypnotics.

7 sychotics, antidepressants, anxiolytics, and hypnotics.

8 ects of neurobiological response to sedative-hypnotics.

9 re anxiety that was unresponsive to sedative hypnotics.

10 n and need for constant infusion of sedative-hypnotics.

11 easing the use of antipsychotics or sedative-hypnotics.

12 ystem and to thereby determine their role in hypnotic action.

13 binding density, abuse liability, subjective hypnotic actions and seizure susceptibility, we assessed

14 ocus coeruleus, it may support analgesic and hypnotic actions attributed to inhibition of those neuro

15 ired for the sedative, and contribute to the hypnotic actions of this anesthetic.

16 termination of their potency and duration of hypnotic activity in mice after intravenous administrati

17 Etomidate is a nonbarbiturate sedative hypnotic agent with no analgesic properties.

18 Propofol is also a sedative hypnotic agent with rapid onset and short duration of ac

19 ave been implicated in responses to sedative/hypnotic agents (including neuroactive steroids), anxiet

20 ICDs under conscious sedation with combined hypnotic agents and deep sedation with etomidate is a sa

21 atory using conscious sedation with combined hypnotic agents and deep sedation with etomidate.

22 sensitive targets for several commonly used hypnotic agents and mediate tonic neuronal inhibition.

23 Among hypnotic agents that enhance GABAA receptor function, et

24 thesiology are employing new potent sedative hypnotic agents to accomplish effective pediatric sedati

25 ies have shown that a wide range of sedative/hypnotic agents, including ethanol, induce sleep when mi

26 s anticonvulsants, anxiolytics, and sedative-hypnotic agents.

27 used as anxiolytics, and for short-half-life hypnotics (all zopiclone).

28 was to estimate the risk of repeated use of hypnotics among individuals with celiac disease as a pro

29 s received painful thermal stimuli following hypnotic analgesia on their own hand, but also when they

30 two standardized scales, and then exposed to hypnotic analgesia training to control cold pressor pain

31 trical activity) of intact resting muscle by hypnotics, analgesia is required to prevent pain-evoked

32 ubunit containing GABAARs contributes to the hypnotic and amnestic actions of the intravenous anesthe

33 Anxiolytic/sedative/hypnotic and antidepressant medication use were independ

34 nes, which are often used for their sedative/hypnotic and anxiolytic effects.

35 e we report that ENT1-null mice show reduced hypnotic and ataxic responses to ethanol and greater con

36 We conclude that both hypnotic and non-hypnotic doses of benzodiazepines may b

37 inazolinone, Quaalude), an infamous sedative-hypnotic and recreational drug from the 1960s-1970s.

38 variety of behavioral responses to sedative-hypnotics and may directly facilitate progress in human

39 icularly addressing the fields of sedatives, hypnotics and neuromuscular blockers, however, there is

40 Regional anesthesia, as well as hypnotics and opioids, promotes intraoperative muscle re

41 Despite widespread use of standard hypnotics and sedating antidepressants for chronic insom

42 For the induction dose of hypnotics and the initial dose of other drugs that have

43 of a structurally diverse group of sedative, hypnotic, and anesthetic drugs, including the volatile a

44 and to test their contributions to sedative, hypnotic, and immobilizing anesthetic actions.

45 Daily doses of all opioid, sedative, hypnotic, and major tranquilizer drugs administered to e

46 ct as endogenous anxiolytic, anticonvulsant, hypnotic, and sedative agents, actions that are principa

47 dosages of antidepressants, antipsychotics, hypnotics, and antidementia medications were allowed.

48 re antidepressants, antipsychotics, sedative-hypnotics, and antidepressant-antipsychotic combinations

49 tonin reuptake inhibitors, nonbenzodiazepine hypnotics, and antihistamines for more than 4 weeks was

50 y alcohol, marijuana or cocaine, anesthetics/hypnotics, and oral opioids.

51 n reached on the precise mechanisms by which hypnotic anesthetic agents produce their effects.

52 se of the BIS monitor results in less use of hypnotic anesthetic drugs, decreased time to extubation,

53 Chlormethiazole has sedative, hypnotic, anticonvulsant and neuroprotective properties.

54 Epidemiological studies show that hypnotics are associated with an increased risk for suic

55 This review focused on modern, FDA-approved hypnotics, beginning with the introduction of benzodiaze

56 This review focused on modern, FDA-approved hypnotics, beginning with the introduction of benzodiaze

57 the anxiolytic, anticonvulsant, and sedative-hypnotic benzodiazepines.

58 of using benzodiazepines, nonbenzodiazepine hypnotics, beta-blockers, selective serotonin reuptake i

59 cern is that benzodiazepine receptor agonist hypnotics can cause parasomnias, which in rare cases may

60 also accumulating evidence of high levels of hypnotic capacity in all groups with dissociative sympto

61 e hypersensitive to melatonin, but not other hypnotic compounds.

62 Focused hypnotic concentration is a model for brain control over

63 , 1.87; 95% CI, 1.70-2.06), receive sedative hypnotics concurrently (40.7% vs 7.6%, adjusted RR, 5.46

64 rivation, and can be induced by conventional hypnotics, diazepam and sodium pentobarbital.

65 data indicating parallels between controlled hypnotic dissociative states and uncontrolled pathologic

66 lipopolysaccharide immediately followed by a hypnotic dose of etomidate, carboetomidate, or vehicle a

67 We conclude that both hypnotic and non-hypnotic doses of benzodiazepines may be associated with

68 ntral apnea, we administered nonhypnotic and hypnotic doses of diazepam to nine adult male Sprague-Da

69 bral cortical levels of 3alpha,5alpha-THP at hypnotic doses of ethanol.

70 Propofol is the most commonly used sedative-hypnotic drug for noxious procedures, yet the molecular

71 , these data suggest little or no benefit of hypnotic drug treatment on neurogenesis parameters in yo

72 Previous studies of sleep and hypnotic drug use in space have been limited to post-fli

73 hy, and subjective sleep characteristics and hypnotic drug use via daily logs, in-flight and during E

74 Antianxiety or hypnotic drug visits, previously the largest category, d

75 sedative, and analgesic effects of the novel hypnotic drug, gaboxadol.

76 ut it should be applicable to other sedative/hypnotic drugs and to testing cerebellar mutant mice or

77 ugs, diabetes drugs, antihypertensive drugs, hypnotic drugs approved for the treatment of insomnia [s

78 Approved hypnotic drugs have clearly been shown to improve subjec

79 ession, self-reported general health, use of hypnotic drugs or other medications, time spent in bed a

80 owever, we show that the ability of sedative/hypnotic drugs to enhance tonic inhibition in the mouse

81 ers when considering the ability of sedative/hypnotic drugs to enhance tonic inhibition.

82 The use of antianxiety/hypnotic drugs was significantly higher for women in car

83 Whether the administration of hypnotic drugs, by promoting sleep, especially in older

84 neurosteroids, antiepileptics, and sedative/hypnotic drugs.

85 ta, USA) and novel 'soft-drug' sedatives and hypnotics (e.g. CNS-7259X and TD-4756) as well as a nove

86 MP system of the LC in the modulation of the hypnotic effect of alpha-2 adrenergic agonists remains u

87 ponent of the neuronal pathway mediating the hypnotic effect of ethanol and its antagonism by Ro15-45

88 5alpha-THP levels in cerebral cortex and the hypnotic effect of ethanol.

89 possibility is that anesthetics exert their hypnotic effects by hijacking endogenous arousal circuit

90 ral cortical levels of 3alpha,5alpha-THP and hypnotic effects in male rats.

91 o-cortical pathways seem to be linked to the hypnotic effects of anesthesia and deep sedation.

92 The hypnotic effects of ethanol are also substantially dimin

93 However, the mechanisms of hypnotic effects of ethanol remain unclear.

94 indicate that A2AR is a key receptor for the hypnotic effects of ethanol, and pretreatment of caffein

95 mice are also less sensitive to the sedative/hypnotic effects of ethanol, as shown by more rapid reco

96 caffeine might be a strategy to counter the hypnotic effects of ethanol.

97 ral intoxication, as assayed by the sedative/hypnotic effects of ethanol.

98 al development and tolerance to the sedative-hypnotic effects of GABA(A)R positive modulators.

99 contributors to sedative, immobilizing, and hypnotic effects of intravenous anesthetics, a role for

100 utyric acid-A receptor is likely to have the hypnotic effects of propofol without the cardiac depress

101 ecessarily the only) anatomic site mediating hypnotic effects of these compounds.

102 hanol and are more sensitive to the sedative/hypnotic effects of this drug than controls.

103 channels, and thereby achieve their sedative-hypnotic effects.

104 ay a role in their immobilizing and sedative-hypnotic effects.

105 tion with both doses of ethanol, blocked its hypnotic effects.

106 evelop rapid tolerance to ethanol's sedative/hypnotic effects.

107 han other relaxation strategies that include hypnotic elements.

108 observational studies suggested that use of hypnotics for insomnia was associated with increased ris

109 its, including diverse responses to sedative-hypnotics, have been detected on distal chromosome 1 in

110 icity from accentuated responses to sedative hypnotics in active cocaine-abusing subjects.

111 ing evidence-based guidelines for the use of hypnotics in the management of chronic insomnia.

112 the evidence for and against the claim that hypnotics increase the risk of suicide.

113 s anxiolytics, anticonvulsants, and sedative/hypnotics is limited by rapid metabolism.

114 Hypnotic maintenance was performed with sevoflurane 3% o

115 receive a prescription for antidepressant or hypnotic medication and to attend their GP both before a

116 ity result from CNS impairments from a given hypnotic medication or whether such medication decreases

117 to received antidepressants and antianxiety/hypnotic medications (five and three times more likely,

118 Hypnotic medications are also efficacious but must be ca

119 The review findings indicate that hypnotic medications are associated with suicidal ideati

120 tidepressant, antipsychotic, anxiolytic, and hypnotic medications in the 12 weeks before and after Se

121 inguish between these possibilities, we used hypnotic medications to control the amount of NREM sleep

122 hood of receiving antidepressant/antianxiety/hypnotic medications, and the number of psychotherapy se

123 ep regulation and for screening new types of hypnotic medications.

124 included in the prescribing information for hypnotic medications.

125 and/or HCRTR2 are considered to be potential hypnotic medications.

126 Evidence for benzodiazepine hypnotics, melatonin agonists, and antidepressants, and

127 al connectivity analysis indicated that this hypnotic modulation of pain responses was associated wit

128 ent treatment with antipsychotic, anxiolytic/hypnotic, mood stabilizer, and stimulant medications.

129 tween DAAs and antidepressants, anxiolytics, hypnotics, mood stabilizers, antipsychotics and treatmen

130 pidem, a widely prescribed nonbenzodiazepine hypnotic, on cell proliferation and survival in the dent

131 Patients may use sedatives, hypnotics, or alcohol in an effort to interrupt this pro

132 tion (TV) and exposure to opioids, sedatives-hypnotics, or general anaesthetics in neonates (O-SH-GA)

133 deaths have been reported from single-agent hypnotic overdoses.

134 pain, and demonstrate the possibility to use hypnotic procedures to modulate higher-level emotional a

135 t of the surgical patient for their sedative/hypnotic properties although the alpha2 adrenoceptor sub

136 data suggest that at least one aspect of the hypnotic properties of adenosine is mediated by a direct

137 ie the increased sensitivity to the sedative/hypnotic properties of ethanol but not the rewarding pro

138 ks and that such actions contribute to their hypnotic properties.

139 equests to provide detailed case reports for hypnotic-related suicide deaths reported through its Adv

140 (n=79), structured attention (n=80), or self-hypnotic relaxation (n=82).

141 Structured attention and self-hypnotic relaxation proved beneficial during invasive me

142 ha2A antisense ODNs significantly change the hypnotic response causing both an increase in latency to

143 f righting reflex following dexmedetomidine; hypnotic response had normalized 8 d after stopping the

144 addition, CIE rats showed remarkably reduced hypnotic response to a benzodiazepine and a steroid anes

145 eus of chronically cannulated rats and their hypnotic response to dexmedetomidine (an alpha2 agonist)

146 adrenoceptor subtype is responsible for the hypnotic response to dexmedetomidine in the locus coerul

147 lation and that the VLPO likely mediates the hypnotic response to high levels of opioid analgesics.

148 ta subunit to GABA pharmacology and sedative/hypnotic responses and behavior and provide insights int

149 onged hypotensive, bradycardic, and sedative-hypnotic responses to alpha(2)AR stimulation.

150 ilin on alpha(2)AR-evoked cardiovascular and hypnotic responses, previously demonstrated to be mediat

151 analgesics (HR, 1.22; 95% CI, 1.08 to 1.37), hypnotics/sedatives (HR, 1.21; 95% CI, 1.07 to 1.37), an

152 analgesics (HR, 1.33; 95% CI, 1.16 to 1.52), hypnotics/sedatives (HR, 1.24; 95% CI, 1.07 to 1.43), GI

153 etomidate had no effect on HCN1 channels and hypnotic sensitivity to etomidate was unaffected by HCN1

154 In addition, hypnotic sensitivity to two other intravenous anesthetic

155 We outline how the hypnotic state can serve as a way to tap neurocognitive

156 bility/automaticity that characterize formal hypnotic states.

157 There is no association between hypnotics, such as zopiclone, and sleep outcomes, alertn

158 science has not fully exploited hypnosis and hypnotic suggestion as experimental tools.

159 We previously showed that a specific hypnotic suggestion reduces involuntary conflict and alt

160 is study was designed to determine whether a hypnotic suggestion to hinder lexical processing could m

161 and anxiety can be effectively alleviated by hypnotic suggestion, which modulates activity in brain r

162 Participants were stringently screened for hypnotic susceptibility with two standardized scales, an

163 The hypnotic THIP (Gaboxadol) induces SWA and at low, clinic

164 diabetes, hypertension, and beta-blocker or hypnotic treatments.

165 r sleep was defined as >/=2 prescriptions of hypnotics using prospective data from the National Presc

166 pidem (Ambien), a short-acting GABAA agonist hypnotic, we show increased sleep spindle density and de

167 n which neither antidepressants nor sedative/hypnotics were prescribed.

168 ly in elderly patients taking benzodiazepine hypnotics, who comprise a large proportion of the depend

169 99% CI, 6.77-35.31); and 2 or more sedative-hypnotics, with anxiety disorders (OR, 2.13; 99% CI, 1.4

170 .3), is associated with less severe sedative-hypnotic withdrawal.

171 from pentobarbital as well as other sedative-hypnotics (zolpidem and ethanol) versus wild-type litter