ライフサイエンスコーパス: hypochlorite

1 e exquisitely sensitive to killing by sodium hypochlorite.

2 se study of responses to oxidative stress by hypochlorite.

3 rees C) by using 3.3 equiv of aqueous sodium hypochlorite.

4 antibacterial microfiber towel that releases hypochlorite.

5 e algR mutant (PAO700) was more sensitive to hypochlorite.

6 per, 2, 2-azo-bis(2-amidinopropane)-2HCl and hypochlorite.

7 itrobenzyl alcohol in the presence of sodium hypochlorite.

8 s reacted at pH 4.0 with submolar amounts of hypochlorite.

9 triggered in an alkaline solution of sodium hypochlorite.

10 ollowed by chlorination using aqueous sodium hypochlorite.

11 but not the remesothelialization induced by hypochlorite.

12 sulfenic acid by air, hydrogen peroxide and hypochlorite.

13 sence of physiologically relevant amounts of hypochlorite.

14 f degradation of PES/PVP membranes by sodium hypochlorite.

15 d MsrB was more readily killed by nitrite or hypochlorite.

16 through beta-scission of intermediate alkyl hypochlorites.

17 itrate (6.5g.L(-1)), hydroxide (4.0g.L(-1)), hypochlorite (0.2g.L(-1)), starch (5.0g.L(-1)), sucrose

18 mol 1)(-1) hr(-1) and K(M) = 39 +/- 4 mM for hypochlorite ([1] = 70 microM), with first-order kinetic

19 to tonometer prisms can be caused by sodium hypochlorite, 70% isopropyl alcohol, 3% hydrogen peroxid

20 Using hypochlorite, a neutrophil-derived oxidant, we show that

21 Using sodium hypochlorite, a powerful oxidant produced by the H2O2-my

22 of insulin was modified per two molecules of hypochlorite added, as estimated by HPLC of native and m

23 Concomitantly, the nonspecific activity of hypochlorite also damages host proteins, and the accumul

24 Hypochlorite, an oxidant generated in vivo by the innate

25 All 3 HSV studies concluded that both sodium hypochlorite and 70% isopropyl alcohol eliminated HSV.

26 With aqueous hypochlorite and a phase transfer catalyst, secondary al

27 examined at three types of shocks (chromium, hypochlorite and acetate) in a batch-mode chamber, and e

28 nd subsequent recombination of the resulting hypochlorite and compound I.

29 TRPA1 channels were strongly activated by hypochlorite and hydrogen peroxide in primary sensory ne

30 than common oxidising agents, such as sodium hypochlorite and hydrogen peroxide.

31 We now report that while hypochlorite and hydroxyl radical both modify amino acid

32 , bicarbonate, hydrosulphide, peroxynitrite, hypochlorite and hypobromite) a comprehensive overview o

33 Hypochlorite and N-chlorotaurine were also strongly repe

34 Here, we show that hypochlorite and reactive radical intermediates of the h

35 he addition of two model chemotoxins: sodium hypochlorite and sodium azide, and one model biotoxin, c

36 Gaseous ClN3 generated from sodium azide, hypochlorite, and acetic acid can be explosive if isolat

37 in chloroform, soluble in water and alkaline hypochlorite, and are converted to crotonic acid more sl

38 rite, sodium dichloroisocyanurate, high-test hypochlorite, and generated hypochlorite) for disinfecti

39 Results indicated that hydroxide, hypochlorite, and their protonated forms could react wit

40 alanylglycine (Phe-Gly), reacted with sodium hypochlorite, and these reaction solutions were analyzed

41 -/-) mice displayed profound deficiencies in hypochlorite- and hydrogen peroxide-induced respiratory

42 The hypochlorite anion was identified to be the reactive chl

43 der slightly basic conditions, hydroxide and hypochlorite are primary reactants and their associated

44 assumption of the obligatory involvement of hypochlorite as an intermediate in myeloperoxidase react

45 ation and oxidation of C-H bonds with sodium hypochlorite as terminal oxidant in the presence of acet

46 aliphatic C-H bond chlorination using sodium hypochlorite as the chlorine source.

47 2,3,4-tetrazine is achieved using tert-butyl hypochlorite as the oxidant.

48 ation, whilst in living cells its effects on hypochlorite-associated cytotoxicity were moderate.

49 ofiltration membrane was treated with sodium hypochlorite at different concentrations, pHs and durati

50 ghly vulnerable to carbonyl formation during hypochlorite attack.

51 han the wild type to phenol, chloroform, and hypochlorite but more resistant to diethylpyrocarbonate.

52 indicated that tyrosine was also degraded by hypochlorite, but we could not detect a carbonyl group f

53 ,6-trichloro-m-cresol (5) react with calcium hypochlorite (Ca(OCl)(2)) in MeOH to give respectively d

54 modify amino acid residues on alpha 2M, only hypochlorite can abolish the ability of alpha 2M to inhi

55 eferred substrate is higher than that of the hypochlorite-Cl system.

56 tions with the CPO-H2O2-Cl system versus the hypochlorite-Cl system.

57 ons between specificities of CPO-H2O2-Cl and hypochlorite-Cl systems indicate that at least 98% of th

58 0, are the same for both the CPO-H2O2-Cl and hypochlorite-Cl systems.

59 Swimmers exposed to hypochlorite (ClO(-))-containing water show a higher ris

60 Oxidation of alpha2M* using 200 microM hypochlorite completely abolishes its binding to LRP wit

61 oduced O2 and is controlled primarily by the hypochlorite concentration and pH.

62 and PIP membranes increased with increasing hypochlorite concentration whereas it decreased for coat

63 H solution) and oxidized at different sodium hypochlorite concentrations (1.0%, 1.5%, and 2.0% of act

64 he drain bulb twice daily with dilute sodium hypochlorite (Dakin's) solution.

65 es, such as formaldehyde, hydrogen peroxide, hypochlorite, dichromate, salicylic acid, melamine, and

66 itation; however, washing in the presence of hypochlorite did not significantly increase ascorbate lo

67 of adenovirus 8 concluded that after sodium hypochlorite (dilute bleach) disinfection, the virus was

68 Sodium hypochlorite (dilute bleach) offers effective disinfecti

69 ow amounts of active oxygen species (such as hypochlorite), followed by chromatographic isolation of

70 , human cells exposed to the oxidizing agent hypochlorite, followed by methyl methanesulfanate, respo

71 urate, high-test hypochlorite, and generated hypochlorite) for disinfection of three surface types (s

72 direct activation of mammalian chaperones by hypochlorite has not, to our knowledge, been previously

73 oxidants sodium metaperiodate and tert-butyl hypochlorite have been replaced by trichloroisocyanuric

74 Hypochlorite (HOCl) is an important component of the inn

75 he effects of selective protein oxidation by hypochlorite (HOCl) on the structure, stability, and rem

76 n primary human keratinocytes, we found that hypochlorite (HOCl) reversibly inhibited the expression

77 rogen peroxide (H(2)O(2)), hypochlorous acid/hypochlorite (HOCl/OCl(-)), and singlet oxygen (O(2)((1)

78 apidly than control cells when challenged by hypochlorite, hydrogen peroxide, or ionizing radiation.

79 different oxidizing agents, including sodium hypochlorite, hydrogen peroxide, ozone and sodium period

80 els of peritoneal fibrosis induced by sodium hypochlorite, hyperglycemic dialysis solutions, or TGF-b

81 severe oxidative stress conditions, such as hypochlorite (i.e., bleach) treatment, which leads to wi

82 ased susceptibility to the oxidative biocide hypochlorite in a native and a model bacteria and that t

83 ary methyl ethers into ketones using calcium hypochlorite in aqueous acetonitrile with acetic acid as

84 chlorides to alpha-chloroketones with sodium hypochlorite in glacial acetic acid/acetone.

85 123, AAPH-induced fluorescein bleaching and hypochlorite-induced fluorescein bleaching.

86 n protected at lowest concentrations against hypochlorite-induced hemolysis.

87 In this study, we show that hypochlorite-induced modifications of human alpha2-macro

88 Results confirmed that sodium hypochlorite induces the degradation of both PES and PVP

89 eavage reaction pathway involving trione and hypochlorite intermediates.

90 allylamide to the 2,3-epoxyamide mediated by hypochlorite ion, which is formed in situ by reduction o

91 Hypochlorite is a powerful oxidant produced by neutrophi

92 Sodium hypochlorite is an effective irrigant for chemical debri

93 ings are consistent with a mechanism whereby hypochlorite is generated in the RebH active site from t

94 hing oxidized metabolites and decreasing the hypochlorite-mediated amplification of intracellular rea

95 en structurally different flavonoids against hypochlorite-mediated changes in in vitro systems, with

96 n was found to be the best protector against hypochlorite-mediated fluorescein bleaching and BSA thio

97 te aqueous media, and the detection limit of hypochlorite-mediated oxidation to the receptor in nanom

98 Here, we show that hypochlorite-modified alpha2M delivers its misfolded car

99 The chaperone activity of hypochlorite-modified alpha2M involves the formation of

100 About 5% of the hypochlorite-modified insulin reacted with dinitrophenyl

101 Although active MPO and hypochlorite-modified proteins and peptides have been de

102 ge from 6.5 to 8.5 in the presence of sodium hypochlorite, monochloramine, and chlorine dioxide.

103 Sodium hypochlorite (NaClO) is commonly applied in membrane cle

104 ericidal mechanism of SlAEW, AEW, and sodium hypochlorite (NaOCl) solutions against Vibrio parahaemol

105 proteins of hydrogen peroxide (H(2)O(2)) and hypochlorite (NaOCl) stress in vivo.

106 chlorhexidine (CHX; 0.2% and 1%), and sodium hypochlorite (NaOCl; 2.5%, 4.5%, and 5.25%) at different

107 cial bleach (approximately 5% aqueous sodium hypochlorite), nickel(II) chloride or nickel(II) acetate

108 orine (Cl(2)), hypochlorous acid (HOCl), and hypochlorite (OCl(-))) are known to produce toxic inorga

109 that environment it is capable of producing hypochlorite (OCl(-)), a chemically more powerful oxidan

110 By employing the oxidation property of hypochlorite (OCl(-)), a novel rhodamine-based hydrazide

111 ulations of hydrogen peroxide (H(2)O(2)) and hypochlorite (OCl(-)).

112 e reaction of thiocarbamate (H2NC(=O)S-) and hypochlorite (OCl-).

113 AN chlorination via nucleophilic addition of hypochlorite on the nitrile carbon.

114 his study investigated the effects of sodium hypochlorite oxidation and a heat-moisture treatment of

115 cation of the general method based on sodium hypochlorite oxidation and o-phthaldialdehyde (OPA)-thio

116 These results provide strong evidence that hypochlorite oxidation contributes to enhanced tissue de

117 Hypochlorite oxidation of methylamine-treated alpha2M (a

118 nzoic acid (IBX-esters) were prepared by the hypochlorite oxidation of the corresponding 2-iodobenzoa

119 Hypochlorite oxidation on polycrystalline platinum yield

120 Extensively copper- and hypochlorite-oxidized LDL bound poorly to versican and b

121 N-Cl-DCAM by forming a hydrogen bond between hypochlorite oxygen and amino hydrogen.

122 iodide with strong oxidant additives (e.g., hypochlorite, persulfate, hydrogen peroxide) and subsequ

123 As a result, YjiE specifically confers hypochlorite resistance to E. coli cells.

124 g to its function, YjiE is now renamed HypT (hypochlorite-responsive transcription factor).

125 Here, we identified a hypochlorite-responsive transcription factor, YjiE, whic

126 pha2-macroglobulin (alpha2M) with 125 microM hypochlorite results in the exposure of its receptor-bin

127 Despite use of a calcium hypochlorite sanitizing procedure to pretreat seeds befo

128 argonidin and catechin, with less impressive hypochlorite scavenging activity in cell-free assays, we

129 ide, nitric oxide, tert-butyl hydroperoxide, hypochlorite, singlet oxygen, ozone, and hydroxyl radica

130 efficacy of four chlorine solutions (sodium hypochlorite, sodium dichloroisocyanurate, high-test hyp

131 semi-aromatic PA membranes were treated with hypochlorite solution and analyzed by X-ray photoelectro

132 ing seeds in a 20,000 mg/liter (ppm) calcium hypochlorite solution before sprouting is recommended to

133 e with commercially available aqueous sodium hypochlorite solution in a 2:5 mixture of acetic acid/ac

134 interventions with a chlorhexidine disc and hypochlorite solution reduce bacterial colonization of d

135 taminated seeds in a 20,000 mg/liter calcium hypochlorite solution reduces, but does not eliminate, t

136 on was even more efficient when using sodium hypochlorite solutions.

137 trapped chromophoric species (3) as a nickel-hypochlorite species.

138 of HOCl in fighting bacterial infections, no hypochlorite-specific stress response has been identifie

139 o our knowledge, YjiE is the first described hypochlorite-specific transcription factor.

140 expression in Mycobacterium smegmatis under hypochlorite stress.

141 .5-fold (p-value < 0.05) in abundance during hypochlorite stress.

142 YjiE regulates a large number of genes upon hypochlorite stress.

143 Such smaller oligomers are predominant in hypochlorite-stressed cells and are the active species a

144 spores exhibited no increased sensitivity to hypochlorite, suggesting that these spores have no signi

145 to be more susceptible to hydrogen peroxide, hypochlorite, superoxide, and singlet oxygen.

146 Here, we showed that both hypochlorite, the oxidizing mediator of chlorine, and hy

147 er and chlorinated by the addition of sodium hypochlorite to give a free chlorine residual of 3 mg/L.

148 dimer and catalyzes the conversion of sodium hypochlorite to molecular oxygen.

149 hosphate disks were then rinsed in 5% sodium hypochlorite to remove adherent osteoclasts, and substra

150 embryo homogenates and treated with alkaline hypochlorite to remove any associated membranous materia

151 Prevention of degradation by sodium hypochlorite treatment of trypsin reagent identified the

152 ive against 3-chlorotyrosine formation after hypochlorite treatment.

153 ability in response to small doses of sodium hypochlorite were seen nearly instantaneously in all cel

154 basis, we analyzed the effects of copper and hypochlorite (which preferentially oxidize lipids and pr

155 This latter is easily oxidized by sodium hypochlorite, which leads to an increase in the negative

156 se porphyrin Mn(TPP)Cl 1, reaction of sodium hypochlorite with different unactivated alkanes afforded

157 Regarding the mechanism, reaction of sodium hypochlorite with the Mn(III) porphyrin is expected to a

158 eatment of gemfibrozil solutions with sodium hypochlorite yielded a 4'-chlorinated gemfibrozil analog