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1 l branch of the vagus, glossopharyngeal, and hypoglossal.
2 receptor subtypes 2A, 2C, or 7 on intrinsic hypoglossal activity and on serotonin agonist (serotonin
5 oduct Fos in trigeminal regions that receive hypoglossal afferents from the tongue and syrinx (the ma
9 was evident until 2 months had elapsed when hypoglossal amplitudes were significantly decreased bila
13 There was also substantial loss of cranial (hypoglossal and facial) motoneurons in the muscle-defici
17 identified the rostrocaudal distribution of hypoglossal and trigeminal motor nuclei, and their senso
18 ent uptake of sulforhodamine 101, peripheral hypoglossal and trigeminal nerves involved with tongue a
20 cture that resonance properties in vibrissa, hypoglossal, and potentially other motoneurones, may ser
21 dal oropharynx with independent and combined hypoglossal branch stimulation and pharyngeal branch of
22 receptor antagonist) to brainstems increased hypoglossal burst frequency and amplitude, with peak dis
23 Our data demonstrate that the size of the hypoglossal canal does not reflect vocal capabilities or
25 based on the hypothesis that the size of the hypoglossal canal is indicative of speech capabilities.
27 indicative of speech was the assumption that hypoglossal canal size is correlated with hypoglossal ne
31 of numerous nonhuman primate taxa that have hypoglossal canals in the modern human size range, both
32 canus, and Australopithecus boisei also have hypoglossal canals that, both absolutely and relative to
33 t, oculomotor/trochlear (cranial nerve 3/4), hypoglossal (cranial nerve 12) and lateral motor column
34 ntrast, trk-ir was no longer seen within the hypoglossal, cuneate, and gracile nuclei at this time po
35 st labeling included the trigeminal, facial, hypoglossal, dorsal vagal motor nuclei, medullary linear
36 e ventral horn of spinal cord and neurons in hypoglossal, facial, trigeminal, and abducens nuclei.
38 aneously from abdominal (AbN), phrenic (PN), hypoglossal (HN) and central vagus nerves from neonatal
39 report here a direct bilateral projection of hypoglossal internuclear interneurons onto facial motone
41 e small in size, and, like classic intrinsic hypoglossal local-circuit interneurons, had several thin
42 nic (104 +/- 7% vs. 57 +/- 5%, P < 0.05) and hypoglossal LTF (46 +/- 13% vs. 28 +/- 10%; P < 0.05).
47 nal (Mo5), facial (Mo7), ambiguus (Amb), and hypoglossal (Mo12) motor nuclei innervate jaw, facial, p
53 ta demonstrate that raphe pallidus inputs to hypoglossal motoneurones are predominantly glutamatergic
54 hilst 5-HT has a direct excitatory action on hypoglossal motoneurones as a result of activation of 5-
55 ther observed that the membrane impedance of hypoglossal motoneurones from both newborn and young ani
56 n anaesthetics on the membrane properties of hypoglossal motoneurones in a neonatal rat brainstem sli
59 recordings of noise-driven discharge in rat hypoglossal motoneurones that support this alternative e
66 At neonatal stage, ROCKalpha is expressed in hypoglossal motoneurons (HMNs) and in their afferent inp
67 erotonin (5-HT) of neonatal and juvenile rat hypoglossal motoneurons (HMs) by using intracellular rec
68 it distribution, we voltage clamped juvenile hypoglossal motoneurons (HMs) from the ventrolateral and
69 whole-cell patch-clamp recordings from mouse hypoglossal motoneurons (HMs) in an in vitro slice prepa
71 s to investigate the actions of clonidine on hypoglossal motoneurons (HMs) in rat brainstem slices.
76 interactions between functionally identified hypoglossal motoneurons and DOR terminals, and that enke
77 inhibitory postsynaptic currents (IPSCs) in hypoglossal motoneurons and its modulation by serotonin.
78 plasmic reticulum (ER) kinase] in facial and hypoglossal motoneurons and persistent upregulation of C
79 facilitatory effect on both ventral horn and hypoglossal motoneurons and that this disfacilitatory me
83 using whole cell patch-clamp recordings from hypoglossal motoneurons in the neonatal rat brainstem sl
86 During AS-carbachol, 86% of the recorded hypoglossal motoneurons were found to be postsynapticall
89 ed cats, we recorded intracellularly from 26 hypoglossal motoneurons which were antidromically activa
90 both the somata and dendrites of HRP-labeled hypoglossal motoneurons with a preponderance of the cont
91 ic contacts with the somata and dendrites of hypoglossal motoneurons with asymmetric specializations.
92 some of which projected to the pre-BotC and hypoglossal motoneurons, colocalized 5-HT and SP, and re
94 ensitivities of native TASK-like currents in hypoglossal motoneurons, which strongly express TASK-1 a
102 (1) robustly promoted the growth of lesioned hypoglossal motor axons, (2) altered the expression and
104 nist and antagonist microinjections into the hypoglossal motor nuclei in adult rats exposed to 3 week
106 ciated proteins in the developing facial and hypoglossal motor nuclei were examined in the Brazilian
107 sal nerves stimulation labeled the bilateral hypoglossal motor nuclei, the trigeminal motor nuclei, t
109 the pre-Botzinger complex (pre-BotC) and the hypoglossal motor nucleus (XIIMN), which are neuronal po
112 rom the supratrigeminal region (Vsup) to the hypoglossal motor nucleus were studied in rats using ant
113 eactivity was also common in neurones of the hypoglossal motor nucleus, inferior olive, hippocampus a
114 The lesion did not prevent growth of the hypoglossal motor nucleus, which does not receive direct
119 months), male rats no longer exhibit LTF of hypoglossal motor output; phrenic LTF is significantly r
120 w that muscarinic receptor antagonism at the hypoglossal motor pool prevents the inhibition of geniog
121 rgic-GIRK channel mechanism operating at the hypoglossal motor pool that has its largest inhibitory i
123 ction and mastication, including the facial, hypoglossal, motor trigeminal, and dorsal motor vagus nu
125 n we (i) attempted to redirect hypobranchial/hypoglossal muscle precursors towards various attractant
126 oat and tongue (hypopharyngeal/hypobranchial/hypoglossal muscle precursors, HMP) that take a stereoty
129 insufficiency, as evidenced by a loss of the hypoglossal nerve (cranial nerve XII) in embryos from th
130 iratory-related rhythmic motor activity from hypoglossal nerve (XIIn) and patch-clamped preBotC inspi
131 iratory-related rhythmic motor output in the hypoglossal nerve (XIIn) to 84 % (without IBMX) and to 7
134 tivation, increased the respiratory rate and hypoglossal nerve activity, induced c-fos expression in
135 analysis of MVBs in the normal postnatal rat hypoglossal nerve and under a variety of experimental co
136 o the magnitude of motor output; respiratory hypoglossal nerve discharge decreased and its frequency
137 hesize that the presence of afferents in the hypoglossal nerve is a derived characteristic of anurans
138 from stimulation of the medial branch of the hypoglossal nerve is predominantly due to ventral displa
139 suggested that afferents are present in the hypoglossal nerve of the leopard frog, Rana pipiens.
140 2A antagonist, MDL-100907, dropped intrinsic hypoglossal nerve respiratory activity by 61 +/- 6% (p <
142 weeks of intermittent hypoxia showed reduced hypoglossal nerve responsiveness (logEC50) for serotonin
143 at hypoglossal canal size is correlated with hypoglossal nerve size, which in turn is related to tong
145 ral and central endings of the branch of the hypoglossal nerve that supplies the syrinx, the tracheos
148 rupted vocal behavior, whereas lesion of the hypoglossal nerve to the tongue exerted no obvious disru
150 y neurons from the tongue that ascend in the hypoglossal nerve were identified and described in the l
151 ats underwent unilateral transections of the hypoglossal nerve, followed by intramedullary grafts of
152 apparent correlation between the size of the hypoglossal nerve, or the number of axons it contains, a
158 but not exclusively, via stimulation of the hypoglossal nerves and also increases upstream resistanc
159 f transecting the cervical strap muscles and hypoglossal nerves on airflow dynamics during hypercapni
160 hodamine 101 uptake after the trigeminal and hypoglossal nerves stimulation labeled the bilateral hyp
161 cular septal defect, abnormal development of hypoglossal nerves, and defective remodeling of the aort
162 nd N-methyl-D-aspartate excitatory output of hypoglossal nerves, and that reduced excitatory responsi
166 ed the cholinergic phenotype in 84 +/- 6% of hypoglossal neurons compared with 39 +/- 6% in control a
168 merald, and Fluoro-Gold) into the facial and hypoglossal nuclei of the rat, we report here a direct b
169 of different tracers into the facial and the hypoglossal nuclei revealed a small, but constant, numbe
171 ear, solitary, raphe, spinal trigeminal, and hypoglossal nuclei, as well as the vestibular complex an
172 ar formation that project to both facial and hypoglossal nuclei, could be involved in oro-facial coor
177 phenotypes to the motor trigeminal (mV) and hypoglossal nucleus (mXII) has not been fully evaluated.
178 urons and premotor projection neurons to the hypoglossal nucleus (mXII) retrogradely labeled with Flu
179 the enkephalinergic (ENK) innervation of the hypoglossal nucleus (nXII) in the rat was organized diff
182 g density was observed across infancy in the hypoglossal nucleus (regression slope coefficient = 0.00
183 otor nucleus (Vmo), facial nucleus (VII) and hypoglossal nucleus (XII) are also located in the PCRt a
184 axons and axon terminals bilaterally in the hypoglossal nucleus (XII) as well as other regions of th
185 alic trigeminal nucleus (Vme) neurons to the hypoglossal nucleus (XII) motoneurons was studied using
186 orsal PCRt neurons to the motoneurons of the hypoglossal nucleus (XII) were examined at both the ligh
187 control the tongue musculature, namely, the hypoglossal nucleus (XIIN); however, virtually nothing i
188 ns (MNs) in the tracheosyringeal part of the hypoglossal nucleus (XIIts) that receive their synaptic
189 - injections of anterograde tracers into the hypoglossal nucleus - labeled fine varicose nerve fiber
195 of cytoplasmic human TDP-43, only MNs in the hypoglossal nucleus and the SC are lost after 8 weeks of
196 suggest that substance P projections to the hypoglossal nucleus are a subset of serotonergic project
198 on of upper airway (UA) motor neurons in the hypoglossal nucleus by a selective serotonin reuptake in
201 For example, the Forum recognized that the hypoglossal nucleus had been incorrectly identified as t
203 brain atlas, and what was identified as the hypoglossal nucleus in that atlas should instead be call
205 atively moderate and late involvement of the hypoglossal nucleus indicates that, although the general
206 enkephalins acting on DOR but not MOR in the hypoglossal nucleus may play a role in the control of to
207 l), with a trend toward fewer neurons in the hypoglossal nucleus of animals with severe facial nucleu
209 id receptor (MOR) containing elements in the hypoglossal nucleus of the adult cat; and (2) the associ
212 zation of serotonin receptor subtypes in the hypoglossal nucleus provides a focus for the development
214 njection of ROCK or MLCK inhibitors into the hypoglossal nucleus reduced or increased, respectively,
215 microinjection of 5-HT2 antagonists into the hypoglossal nucleus reduces motor activity to a much les
216 ral hypothalamus neurons that project to the hypoglossal nucleus some were determined to be hypocreti
217 release in the ventral horn with that in the hypoglossal nucleus to determine whether the mechanism o
221 motoneurons in the dorsal subdivision of the hypoglossal nucleus were demonstrated using tetramethyl
223 n neurons in the nucleus tractus solitarius, hypoglossal nucleus, and dorsal motor nucleus of the vag
224 terminals were found at the EM level in the hypoglossal nucleus, and none of these terminals contact
225 ne latex microspheres were injected into the hypoglossal nucleus, and then serotonin and peptide dual
226 the pre-Botzinger complex, nucleus ambiguus, hypoglossal nucleus, and ventrolateral subnucleus of sol
227 parent at the light microscopic level in the hypoglossal nucleus, but MOR-like immunoreactive process
228 ain cell groups that directly project to the hypoglossal nucleus, indicating the transneuronal spread
229 as one of the premotor neuronal pools of the hypoglossal nucleus, may coordinate and modulate the act
230 trol system (tracheosyringeal portion of the hypoglossal nucleus, nXIIts, and the syrinx, or vocal or
231 ith cardiopulmonary regulation including the hypoglossal nucleus, subnuclei of the nucleus of the sol
233 lation in the tracheosyringal portion of the hypoglossal nucleus, which innervates the syrinx (the av
252 he phrenic motor function data, no change in hypoglossal output was evident until 2 months had elapse
253 rostral part of M2, with considerably fewer hypoglossal projections arising from the other cortical
254 intermittent hypoxia did not appear to alter hypoglossal response to alpha-amino-3-hydroxy-methylisox
255 atory-related activity was recorded from the hypoglossal rootlet of 700- to 800-microm medullary sect
258 ting spontaneous respiratory-related rhythm, hypoglossal (XII) motoneuronal inspiratory drive current
260 tsynaptic 5-HT type 2 (5-HT(2)) receptors on hypoglossal (XII) motoneurons leads to long-lasting incr
261 tic enhancement of AMPA receptor function in hypoglossal (XII) motoneurons that can be induced by int
262 opulations of brainstem respiratory neurons, hypoglossal (XII) motoneurons, and rhythmogenic (type-1)
263 onin (5-HT)-dependent synaptic plasticity in hypoglossal (XII) motoneurons, which control tongue musc
266 500 microM) pressure microinjection into the hypoglossal (XII) motor nucleus (100-500 nl; pH = 7.2-7.
267 having axonal branches in the region of the hypoglossal (XII) motor nucleus and assess their behavio
268 retains the preBotC, the respiratory-related hypoglossal (XII) motor nucleus and XII premotor circuit
274 2), 5 min intervals), integrated phrenic and hypoglossal (XII) nerve burst amplitudes were increased
275 n to rhythmogenesis, we compared preBotC and hypoglossal (XII) nerve motor activity in medullary slic
278 ibution of GG motoneurons (GGMNs) within the hypoglossal (XII) nucleus has not been studied in the ad
279 ency, whereas injection into the ipsilateral hypoglossal (XII) nucleus induced tonic/seizure-like act
280 active during inspiration and project to the hypoglossal (XII) nucleus that contains motoneurons impo
282 s (P) 0-22) spontaneous rhythmic activity in hypoglossal (XII) rootlets that occur in synchrony with
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