ライフサイエンスコーパス: hypogonadotropic hypogonadism

1 (olfactory dysfunction, delayed puberty and hypogonadotropic hypogonadism).

2 ons include Kallmann syndrome and idiopathic hypogonadotropic hypogonadism.

3 ency, including the rare adult-onset form of hypogonadotropic hypogonadism.

4 elayed puberty, hypothalamic amenorrhea, and hypogonadotropic hypogonadism.

5 immune function, and delayed puberty due to hypogonadotropic hypogonadism.

6 on population in the hypothalamus as well as hypogonadotropic hypogonadism.

7 r characterized by adrenal insufficiency and hypogonadotropic hypogonadism.

8 rized by anosmia and pubertal failure due to hypogonadotropic hypogonadism.

9 at mutations in genes involved in idiopathic hypogonadotropic hypogonadism, a congenital form of GnRH

10 llular loop (IL2) of GPR54 causes idiopathic hypogonadotropic hypogonadism, a disorder characterized

11 d prospectively among 50 men with idiopathic hypogonadotropic hypogonadism after a mean (+/-SD) durat

12 rome AHC, a disorder that is associated with hypogonadotropic hypogonadism also.

13 410K phenotype to include Kallmann syndrome (hypogonadotropic hypogonadism and anosmia), stereotyped

14 Lats1-/- mice are reminiscent of isolated LH-hypogonadotropic hypogonadism and corpus luteum insuffic

15 ate when adjusted for fat-free mass, partial hypogonadotropic hypogonadism and growth failure.

16 e (KS) is a genetic disease characterized by hypogonadotropic hypogonadism and impaired sense of smel

17 microRNA synthesis in GnRH neurons leads to hypogonadotropic hypogonadism and infertility in mice.

18 ve function, as mice lacking miR-7a2 develop hypogonadotropic hypogonadism and infertility.

19 4 prevents the onset of puberty and leads to hypogonadotropic hypogonadism and infertility.

20 fic deletion of Kiss1r (Kiss1r(d/d)) display hypogonadotropic hypogonadism and infertility.

21 ertal timing, including causes of idiopathic hypogonadotropic hypogonadism and Kallmann syndrome.

22 Sustained reversal of normosmic idiopathic hypogonadotropic hypogonadism and the Kallmann syndrome

23 variants in genes associated with idiopathic hypogonadotropic hypogonadism are found in women with hy

24 e (GnRH) receptor mutants from patients with hypogonadotropic hypogonadism are frequently misrouted p

25 defined the sustained reversal of idiopathic hypogonadotropic hypogonadism as the presence of normal

26 The syndrome of hypogonadotropic hypogonadism, ataxia, and dementia can

27 severe gynecomastia of prepubertal onset and hypogonadotropic hypogonadism caused by elevated estroge

28 in neurokinin B (NKB) and its receptor show hypogonadotropic hypogonadism characterised by failure t

29 (NKB) or its receptor, NK3 (NK3R), result in hypogonadotropic hypogonadism, characterized by an absen

30 xpress LepR and inactivation of Kiss1 causes hypogonadotropic hypogonadism, Donato et al., in this is

31 his recessive mutation (GnRHR E(90)K) causes hypogonadotropic hypogonadism (failed puberty associated

32 xome sequencing in a patient with ataxia and hypogonadotropic hypogonadism, followed by targeted sequ

33 opathy, bifid uvula, malignant hyperthermia, hypogonadotropic hypogonadism, growth retardation, hypog

34 lassic GnRH deficiency, men with adult-onset hypogonadotropic hypogonadism had larger mean (+/-SD) te

35 rism, with anterior pituitary hypoplasia and hypogonadotropic hypogonadism, has been reported in pati

36 nked, adrenal hypoplasia congenita (AHC) and hypogonadotropic hypogonadism (HH).

37 inked adrenal hypoplasia congenita (AHC) and hypogonadotropic hypogonadism (HH).

38 Hypogonadotropic hypogonadism (HHG) has been identified

39 erogeneous disorder consisting of idiopathic hypogonadotropic hypogonadism (IHH) and anosmia, and is

40 Idiopathic hypogonadotropic hypogonadism (IHH) due to defects of go

41 Idiopathic hypogonadotropic hypogonadism (IHH) is a condition chara

42 Idiopathic hypogonadotropic hypogonadism (IHH) with anosmia (Kallma

43 erase 1 (HS6ST1) in families with idiopathic hypogonadotropic hypogonadism (IHH).

44 sequence of genes associated with idiopathic hypogonadotropic hypogonadism in 55 women with hypothala

45 r gene, cause autosomal recessive idiopathic hypogonadotropic hypogonadism in humans and mice, sugges

46 n, and mutations or deletions of GPR54 cause hypogonadotropic hypogonadism in humans and mice.

47 nction mutations in the FSHB/Fshb gene cause hypogonadotropic hypogonadism in humans and mice.

48 uggest a basis for adrenal insufficiency and hypogonadotropic hypogonadism in males affected by adren

49 The recognition of adult-onset hypogonadotropic hypogonadism in men as a distinct disor

50 compelling explanation for the occurrence of hypogonadotropic hypogonadism in patients with inactivat

51 hormonal therapy to assess reversibility of hypogonadotropic hypogonadism is reasonable.

52 uman presents either as normosmic idiopathic hypogonadotropic hypogonadism (nIHH) or with anosmia [Ka

53 rtion of 4H (Hypomyelination, Hypodontia and Hypogonadotropic Hypogonadism) or RNA polymerase III (PO

54 The Gpr54-deficient mice had isolated hypogonadotropic hypogonadism (small testes in male mice

55 e describe an adult-onset form of idiopathic hypogonadotropic hypogonadism that develops after pubert

56 1 knockout mice are a novel genetic model of hypogonadotropic hypogonadism that establishes essential

57 ce suffering from adult onset of obesity and hypogonadotropic hypogonadism to study effects of gonado

58 54, and an unrelated proband with idiopathic hypogonadotropic hypogonadism was determined to have two

59 Idiopathic hypogonadotropic hypogonadism was previously thought to

60 nked adrenal hypoplasia congenita (AHC) with hypogonadotropic hypogonadism was recently shown to be c

61 scribe 15 men in whom reversal of idiopathic hypogonadotropic hypogonadism was sustained after discon

62 who lacked pubertal development (idiopathic hypogonadotropic hypogonadism) was examined for mutation

63 Idiopathic hypogonadotropic hypogonadism, which may be associated w

64 n the GNRHR and GPR54 genes cause idiopathic hypogonadotropic hypogonadism with normal olfaction (nIH

65 ompared with six patients who had idiopathic hypogonadotropic hypogonadism without GPR54 mutations.