ライフサイエンスコーパス: hypomania

1 pecific adverse effects were observed (e.g., hypomania).

2 the DSM-5 as cardinal symptoms of mania and hypomania.

3 n would alter the prevalence of mania and/or hypomania.

4 ng placebo discontinued treatment because of hypomania.

5 ajor depression predicted new-onset mania or hypomania.

6 major depression and in episodes of mania or hypomania.

7 h antidepressant treatment-emergent mania or hypomania.

8 h fewer symptoms than required for threshold hypomania.

9 ure to evaluate the workplace costs of mania/hypomania.

10 pomanic symptoms, 57% met criteria for mixed hypomania.

11 ncreased risk of treatment-emergent mania or hypomania.

12 preceding shifts from depression to mania or hypomania.

13 icantly higher rate of switching to mania or hypomania.

14 ncreased risk of treatment-emergent mania or hypomania (0.926 [0.576-1.491], p=0.753), but 52 week ex

15 cantly higher rates of subthreshold mania or hypomania (13.3% compared with 1.2%), manic, mixed, or h

16 re 7 episodes of treatment-emergent mania or hypomania, 5 occurring in the combined treatment group.

17 and mania has been well established, that of hypomania and bipolar II (BPII) disorder has not.

18 e do not support the splitting between mania/hypomania and depression); family history, major depress

19 pathophysiological processes associated with hypomania and depression, along with the particular impa

20 Threshold switches into full-duration hypomania and mania occurred in 11.4% and 7.9%, respecti

21 ty were observed for family history of mania/hypomania and multiple past mood episodes.

22 mania is common in patients with symptoms of hypomania and particularly common in women.

23 er, type I, was admitted to the hospital for hypomania and poorly controlled diabetes mellitus.

24 ixed symptoms increased with the severity of hypomania and then decreased at the most severe levels o

25 [at least 1 but <7 days] or recurrent brief hypomania) and threshold switches (emergence of full-dur

26 rtum period, with a focus on managing mania, hypomania, and the psychotic components of the illness.

27 nical remission, treatment-emergent mania or hypomania, and tolerability (using dropout rates as a pr

28 Taking vulnerability to hypomania as a surrogate model of impulsivity, we utiliz

29 hiatric complications (suicidal attenuation, hypomania) as well as high costs.

30 s who converted did not have any symptoms of hypomania at baseline.

31 patients to demonstrate subsequent mania or hypomania at follow-up.

32 esults indicate steeper delay discounting in hypomania at multiple stages of information processing.

33 hreshold brief hypomania (emergence of brief hypomania [at least 1 but <7 days] or recurrent brief hy

34 s) are episodes of mania (bipolar I, BPI) or hypomania (bipolar II, BPII) interspersed with periods o

35 Although mania and hypomania define bipolar disorder, depressive episodes a

36 hosis to mood disturbance, duration of mania/hypomania, depression, and psychosis) and 10-year outcom

37 ne episode of deep-brain-stimulation-induced hypomania during the blinded on-stimulation period); all

38 e likely than men to experience subthreshold hypomania during visits with depression (40.7% compared

39 rgent affective switch (a switch to mania or hypomania early in the course of treatment) were also ex

40 nse and the occurrence of subthreshold brief hypomania (emergence of brief hypomania [at least 1 but

41 Symptoms of hypomania, even when of low intensity, were frequently a

42 hosis predicted more weeks ill with mania or hypomania (F(1,80) = 12.2, P =.0008).

43 he hypomania-prone group relative to the low hypomania group, indicative of greater reward responsive

44 reshold switches (emergence of full-duration hypomania [> or =7 days] or mania) were blindly assessed

45 (HR = 1.713; 95% CI, 1.373-2.137; P < .001), hypomania (HR = 4.502; 95% CI, 3.466-5.849; P < .001), o

46 order; depression more common than mania and hypomania in bipolar disorders; trait mood lability in m

47 oms in major depressive disorder; factors of hypomania inside major depressive disorder; recurrent co

48 is characterized by episodes of mania and/or hypomania interspersed with periods of depression.

49 Our findings indicate that proneness to hypomania is associated with both reward hypersensitivit

50 Hypomania is associated with impulsive decision making a

51 Mixed hypomania is common in patients with symptoms of hypoman

52 major concern is the risk for mood switch to hypomania, mania, and mixed states.

53 ale scores, and the patients presenting with hypomania, mania, or a mixed state exhibited a 74% decre

54 that manic symptoms below the threshold for hypomania (mixed features) are common in individuals wit

55 ieved recovery, time to recurrence of mania, hypomania, mixed state, or a depressive episode was exam

56 nd those who had treatment-emergent mania or hypomania (N=46).

57 xperienced a switch during the study period (hypomania, N=17; severe hypomania, N=3).

58 ng the study period (hypomania, N=17; severe hypomania, N=3).

59 Hypomania of long or short duration in BP-II seems to be

60 tes (mixed depression) and dysphoric (mixed) hypomania (opposite polarity symptoms in the same episod

61 ar depression (BPD), 30 with current bipolar hypomania or mania (BPM), 15 bipolar euthymic (BPE), and

62 ference between groups in treatment-emergent hypomania or mania (six patients in the modafinil group

63 tive risks of switches in mood polarity into hypomania or mania during acute and continuation trials

64 risks of threshold switches to full-duration hypomania or mania in both acute and long-term continuat

65 The intermediate phenotypes include 1) hypomania or mania not otherwise specified, in which the

66 pomanic symptoms at baseline with subsequent hypomania or mania was determined in survival analyses u

67 n 1 and 3 days in duration, and 2) irritable hypomania or mania, in which the patient has demarcated

68 meet the full DSM-IV diagnostic criteria for hypomania or mania, including the duration criterion, an

69 the presence of symptoms of depression or of hypomania or mania, measured by the Inventory of Depress

70 ntimanic medication (excluding patients with hypomania or mania, mixed symptoms, or rapid cycling).

71 sis, 19.6% (N=108) of the sample experienced hypomania or mania, resulting in revision of diagnoses f

72 onitor course of illness and to identify any hypomania or mania.

73 then decreased at the most severe levels of hypomania or mania.

74 18.7) and MDEs (OR=2.0, CI: 1.5-2.7) but not hypomania (OR=1.3, CI: 0.5-3.6).

75 n was significantly greater for women during hypomania (P<.001).

76 The hypomania-prone group also showed smaller FRN to losses,

77 In the second experiment, the hypomania-prone group evidenced greater differentiation

78 In the first experiment, the hypomania-prone group made significantly more immediate

79 icted, rewards elicited a smaller FRN in the hypomania-prone group relative to the low hypomania grou

80 ty to both reward and punishment outcomes in hypomania-prone individuals not receiving pharmacotherap

81 Patients with subthreshold hypomania (SBP; subthreshold bipolar disorder) were indi

82 Duration of mania/hypomania showed 2 discontinuities demarcating 3 groups:

83 der rather than to stronger effects of mania/hypomania than depression.

84 were significantly more likely to experience hypomania than those with bipolar II disorder.

85 ho underwent sleep restriction reported mild hypomania that was unrelated to weekly sleep duration.

86 56.9% +/- 28.8% of total weeks with mania or hypomania (unipolar or mixed), and 38.7% +/- 28.8% of th

87 tuent episodes (major depression, mania, and hypomania) using interview and best-estimate diagnostic

88 Proneness to hypomania was also associated with greater N1 amplitude

89 Mixed hypomania was defined at a given visit as a Young Mania

90 primary symptom, the prevalence of mania and hypomania was reduced.

91 t that recurrent major depression as well as hypomania was required for a diagnosis of BPII disorder.

92 of threshold switches to subthreshold brief hypomanias was higher in both the acute (ratio=3.60) and

93 of brief (2-6 days) vs longer (> or =7 days) hypomanias were not significantly different on any measu

94 ad developed one or more distinct periods of hypomania, while another 19% had at least one episode of

95 MAIN OUTCOME MEASURES: Mania/hypomania with or without depression among those who met

96 Subthreshold BPD was defined as recurrent hypomania without a major depressive episode or with few