ライフサイエンスコーパス: hypopnea

1 pite falling TP EMG and obstructive apnea or hypopnea.

2 esponsible for the development of apneas and hypopneas.

3 uctive, central, and mixed apnea, as well as hypopneas.

4 er, the hourly rate of episodes of apnea and hypopnea (36 +/- 10 versus 47 +/- 21), episodes of arous

5 he mean (+/- SD) hourly episodes of apnea or hypopnea (36 +/- 25 and 20 +/- 27; P = 0.015), the preva

6 re 40 patients without (hourly rate of apnea/hypopnea, 4 +/- 4; group 1) and 41 patients with (51% of

7 h (51% of all patients; hourly rate of apnea/hypopnea, 44 +/- 19; group 2) sleep apnea.

8 iability during sleep was predicted by apnea-hypopnea and body mass indices.

9 nd fragmentation; standard measures of apnea/hypopnea and periodic leg movement; and results of the m

10 reduced the number of episodes of apnea and hypopnea and the duration of arterial oxyhemoglobin desa

11 of desaturation and/or arousal) to identify hypopneas and apneas.

12 king systems, but the residual events (apnea/hypopnea) and leak data are not as easy to interpret as

13 isturbance index (RDI(Total), sum of apneas, hypopnea, and flow limitation events) of 18 events/h was

14 ereby altering the susceptibility for apnea, hypopnea, and periodic breathing in sleep.

15 a dominant role in the generation of apneas, hypopneas, and snoring in healthy subjects.

16 er design to determine whether apneas and/or hypopneas are temporally associated with episodes of par

17 In contrast, nocturnal rates of apneas and hypopneas, as well as minimal oxygen saturation, did not

18 h percentage of sleep time (>7%) in apnea or hypopnea (both measures of disordered breathing) were as

19 a (OSA) is characterized by repetitive apnea-hypopnea cycles during sleep associated with oxygen desa

20 TI (10 and 15 L/min), obstructive apneas and hypopneas decreased but periodic laryngeal obstructions

21 apnea defined as a cessation of airflow and hypopnea defined as a > or = 30% reduction in airflow or

22 Supplemental O2 significantly reduced hypopnea density, obstructive apnea index, and paradoxic

23 The number of episodes of apnea and hypopnea during sleep decreased 61 percent.

24 Obstructive apneas and hypopneas during sleep are a well recognized cause of ex

25 t Anxiety Scale) and the number of apnea and hypopnea events per hour of sleep (AHI), but were associ

26 was indicated by the frequency of apnea and hypopnea events per hour of sleep, measured by in-labora

27 opause; odds ratios for 15 or more apnea and hypopnea events per hour were 1.1 (0.5, 2.2) with perime

28 confounding factors, for 5 or more apnea and hypopnea events per hour were 1.2 (0.7, 2.2) with perime

29 -hypopnea index (AHI; the number of apnea or hypopnea events per hour, with a score of >/=15 indicati

30 or having 5 or more and 15 or more apnea and hypopnea events per hour.

31 index, and the fraction of events that were hypopneas (Fhypopneas) were independent predictors of th

32 ived from combinations of conventional apnea/hypopnea, flow limitation events (transient elevated upp

33 Men developed more severe hypopnea in response to identical applied external loads

34 However, apnea/hypopnea incidence was similarly increased in both MI-CH

35 t, for clinically defined sleep apnea (apnea/hypopnea index > or = 10 and daytime symptoms), men had

36 lity of life in 122 patients with SDB (apnea-hypopnea index > or = 5 events/hour), this study found t

37 polysomnography between 1992 and 2004 (apnea-hypopnea index > or =15) who subsequently underwent a PC

38 eight/obese matched patients with OSA (apnea-hypopnea index >/= 15 events per hour) and 11 normal-wei

39 OSA (apnea-hypopnea index >/= 5 events/h) was assessed using home-b

40 SDB was characterized by apnea-hypopnea index >/=15 events per hour (polysomnography).

41 -to-severe sleep-disordered breathing (apnea-hypopnea index >/=15%) was significantly higher in parti

42 with newly revascularized CAD and OSA (apnea-hypopnea index >/=15/h) without daytime sleepiness (Epwo

43 aroxysmal AF (43 with >/=moderate OSA [apnea-hypopnea index >/=15] and 43 without OSA [apnea-hypopnea

44 predicted by age >60 years (HR: 5.53), apnea-hypopnea index >20 (HR: 1.60), mean nocturnal O2sat <93%

45 erweight/obese subjects without apnea (apnea-hypopnea index < 15 events per hour) with 25 overweight/

46 normal subjects (n = 15) without SDB (apnea-hypopnea index < 5 events/hour) recruited from the gener

47 erate degrees of sleep apnea (5 < or = apnea-hypopnea index < or = 30).

48 opnea index >/=15] and 43 without OSA [apnea-hypopnea index <5]), right atrial and left atrial voltag

49 ragmentation, all participants with an apnea-hypopnea index (AHI) > or = 1 were analyzed separately.

50 Nasal occlusion increased the apnea hypopnea index (AHI) (occlusion mean = 6.6 +/- 8.0 versu

51 OSA-associated quantitative phenotypes apnea-hypopnea index (AHI) and body mass index (BMI).

52 table monitors, or association between apnea-hypopnea index (AHI) and health outcomes among community

53 A polysomnographically derived apnea-hypopnea index (AHI) and hypoxemia index (percent of sle

54 SDB was quantified with the apnea hypopnea index (AHI) and oxygen desaturation measures.

55 Apnea-hypopnea index (AHI) and percent nighttime with oxygen s

56 ificant dose-relationships between REM apnea-hypopnea index (AHI) and prevalent hypertension.

57 SDB was categorized using the apnea-hypopnea index (AHI) and the hypoxemia index (percent sl

58 for all-cause mortality, with FEV1 and apnea-hypopnea index (AHI) as the primary exposure indicators

59 disordered breathing, depending on the apnea-hypopnea index (AHI) cutoff, ranged from 40 to 60%.

60 te to severe SDB, defined as having an Apnea-Hypopnea Index (AHI) greater than 15 as assessed by poly

61 n fully adjusted models, patients with apnea-hypopnea index (AHI) greater than 30 had a 30% higher ha

62 OSAS was defined by an apnea/hypopnea index (AHI) greater than or equal to 1 event/h,

63 on a nondialysis day, subjects with an apnea-hypopnea index (AHI) greater than or equal to 20 had flu

64 nce of periodontal disease between the apnea-hypopnea index (AHI) groups, with a negligible Spearman

65 ation of head and facial form with the apnea hypopnea index (AHI) in 364 white individuals and 165 Af

66 Women with an apnea-hypopnea index (AHI) less than 10 comprised the control

67 Women with an apnea-hypopnea index (AHI) less than 10 were the control group

68 Patients with an apnea-hypopnea index (AHI) less than 15 were the control group

69 nts with resistant hypertension and an apnea-hypopnea index (AHI) of 15 or higher.

70 r ejection fraction of 45% or less, an apnea-hypopnea index (AHI) of 15 or more events (occurrences o

71 A total of 14.7% of subjects with an apnea-hypopnea index (AHI) of 15 or more had a diagnosis of di

72 ently diagnosed (<6 months) OSA and an apnea-hypopnea index (AHI) of 20 events/hour or more.

73 The prevalence varies based on the apnea-hypopnea index (AHI) threshold used for the evaluation (

74 olution of symptoms and a reduction in Apnea/Hypopnea Index (AHI) to < 5/h, and partial response (PR)

75 Mean apnea-hypopnea index (AHI) was 52.6 +/- 28.2 (SD) events/h wit

76 The apnea-hypopnea index (AHI) was derived from standardized sleep

77 OSA, physiological data including the apnea-hypopnea index (AHI), and nocturnal oxygen saturation (O

78 have variable success at reducing the apnea-hypopnea index (AHI), and predicting responders is chall

79 ith hsCRP and MRP 8/14 levels and with apnea-hypopnea index (AHI), BMI z score, and apolipoprotein B

80 ur main exposures were the obstructive apnea-hypopnea index (AHI), central apnea index (CAI >/= 5), a

81 o four severity groups on the basis of apnea-hypopnea index (AHI), followed by comparisons of cogniti

82 In combination with apnea-hypopnea index (AHI), identification of "respiratory eve

83 associated with a 55% reduction in the apnea-hypopnea index (AHI), which decreased from a preflight v

84 rdered breathing was quantified by the apnea-hypopnea index (AHI)-the average number of apneas and hy

85 e diagnosis of OSAS and calculation of Apnea-Hypopnea Index (AHI).

86 hours of use, mask leak, and residual apnea-hypopnea index (AHI).

87 divided into 3 sub-groups based on the apnea/hypopnea index (AHI): mild, moderate, or severe OSA.

88 OSA severity was defined by the apnea-hypopnea index (AHI): severe >30, moderate >15-30, mild

89 Apnea-hypopnea index (AHI, the average number of apneas plus h

90 Outcome measures included apnea-hypopnea index (AHI; average number of apneas plus hypop

91 The primary outcome measures were the apnea-hypopnea index (AHI; the number of apnea or hypopnea eve

92 channel home polysomnography, were the apnea-hypopnea index (average number of apneas/hypopneas per h

93 ea (OR, 6.31; 95% CI, 1.94-20.51), and apnea-hypopnea index (OR, 1.22; 95% CI, 1.08-1.39 [per 5-unit

94 iated with significant improvements in apnea-hypopnea index (P < 0.001); microarousal index (P = 0.00

95 y with DeltaNC (r=-0.755, P<0.001) and apnea-hypopnea index (r=-0.765, P<0.001), it did not in women.

96 t positive correlation between SAA and apnea-hypopnea index (r=0.40, P=0.03).

97 n diffusivity correlated with a higher apnea hypopnea index (Spearman's r = -0.50, p = 0.008) and a g

98 isordered breathing, as defined by the apnea-hypopnea index (the number of episodes of apnea and hypo

99 le) with Cheyne-Stokes breathing (mean apnea-hypopnea index 19.8 [SD 2.6] and stable symptomatic chro

100 leep laboratory and clinical criteria (apnea/hypopnea index [AHI] > or = 10 and the presence of dayti

101 ersomnolence in 741 patients with SDB (apnea-hypopnea index [AHI] >/= 10 events/h).

102 he 24-h prevalence of predominant CAs (apnea/hypopnea index [AHI] >/=5 events/h, with CA of >50%) was

103 e new outpatients diagnosed with SAHS (apnea/hypopnea index [AHI] >or= 5/hour, and >or= 2 symptoms in

104 1997, and had to have normal results (apnea hypopnea index [AHI] <5).

105 cal responses (>/=50% reduction in the apnea-hypopnea index [AHI] and <10 events/hour) in patients wi

106 ipants were identified as free of OSA (apnea-hypopnea index [AHI] of <5 events/h and not treated) by

107 1.00 to 1.21] per 10-unit increase in apnea-hypopnea index [AHI]) but not in older men or in women o

108 126 patients with moderate-severe OSA (apnea hypopnea index [AHI], 25.6 [SD 12.3]) were randomly assi

109 patients (55 males, 13 females; median apnea-hypopnea index [AHI], 35) not receiving hypotensive medi

110 We examined 55 sleep apnea probands (apnea-hypopnea index [AHI]: 43.2 +/- 26.3 events/h), 55 proban

111 tal of 25 adults with positional OSAS (apnea-hypopnea index [AHI]supine:AHInon-supine >/= 2) were pro

112 each interval, we assessed the median apnea-hypopnea index and the relative risk of sudden death fro

113 -year follow-up study according to the apnea-hypopnea index at base line were estimated after adjustm

114 nt CVD experienced larger increases in apnea-hypopnea index between polysomnograms.

115 relation of incident CVD to change in apnea-hypopnea index between the 2 polysomnograms was tested w

116 The difference in adjusted mean apnea-hypopnea index change between subjects with and without

117 causes during other intervals, and the apnea-hypopnea index correlated directly with the relative ris

118 Mean number of events measured by the apnea-hypopnea index decreased from 35.7/h to 2.1/h at 6 month

119 pothesis, we correlated loop gain with apnea-hypopnea index during supine, nonrapid eye movement slee

120 ation of all children with obstructive apnea-hypopnea index greater than 5/hour total sleep time in a

121 non-REM sleep was quantified using the apnea-hypopnea index in REM (AHIREM) and non-REM sleep (AHINRE

122 lation was found between loop gain and apnea-hypopnea index in the atmospheric group only (r = 0.88,

123 At baseline, the mean apnea-hypopnea index in the patients with the syndrome was 35,

124 aphy, and severe SDB was defined as an apnea-hypopnea index of >30 per hour of sleep.

125 lative to the reference category of an apnea-hypopnea index of 0 events per hour at base line, the od

126 idence interval, 1.13 to 1.78) with an apnea-hypopnea index of 0.1 to 4.9 events per hour at base lin

127 sted rate ratio [caffeine/placebo] for apnea-hypopnea index of 0.89 [95% CI = 0.55-1.43]; P = 0.63).

128 disordered breathing was defined as an apnea-hypopnea index of 15 or more events per hour of sleep.

129 valence of sleep-disordered breathing (apnea-hypopnea index of 15 or more) among hormone users (61 of

130 Participants with an apnea-hypopnea index of 15 to 50 events per hour were randomly

131 idence interval, 1.46 to 5.64) with an apnea-hypopnea index of 15.0 or more events per hour.

132 ndrome was 35, as compared with a mean apnea-hypopnea index of 2 in the comparison group.

133 tive patients were enrolled who had an apnea-hypopnea index of 20 h(-1) or greater and an Epworth Sle

134 e sleep apnea syndrome was based on an apnea-hypopnea index of 5 or higher (five or more events per h

135 idence interval, 1.29 to 3.17) with an apnea-hypopnea index of 5.0 to 14.9 events per hour, and 2.89

136 ore events per hour); patients with an apnea-hypopnea index of less than 5 served as the comparison g

137 An apnea-hypopnea index of more than 10 per hour was significantl

138 ere total sleep time on actigraphy and apnea-hypopnea index on polysomnography.

139 isordered breathing was ascertained by apnea-hypopnea index or clinical diagnosis.

140 t to 6 a.m. had a significantly higher apnea-hypopnea index than those with sudden death from cardiac

141 cardiovascular events with increasing apnea-hypopnea index values.

142 90 m than placebo and autoCPAP: median apnea/hypopnea index was 5.8 events per hour (5.8/h) (IQR, 3.0

143 Mean (SEM) apnea-hypopnea index was also significantly higher in particip

144 Initially, the apnea-hypopnea index was determined by polysomnography followe

145 The mean (+/-SD) of apnea-hypopnea index was significantly higher in patients with

146 (1,839 in fully adjusted models), the apnea-hypopnea index was used to classify OSA as none (0-4.9/h

147 rth Sleepiness Scale score >10) and an apnea-hypopnea index with 3% desaturation and from 5 to 30 eve

148 pneas and hypopneas per hour of sleep (apnea-hypopnea index) was determined by unattended, single-nig

149 ath, sleep study measures (such as the Apnea-Hypopnea Index), measures of cardiovascular status (such

150 diagnosed with moderate to severe OSA (apnea-hypopnea index, >/=15) in 19 Spanish sleep units.

151 ss: severe sleep-disordered breathing (apnea-hypopnea index, >30 episodes/hr), self-report of poor sl

152 to each criterion that was satisfied: (apnea-hypopnea index, <30 events per hour) + (nadir oxygen sat

153 Seventy-one subjects (ages, 55-76 yr; apnea-hypopnea index, 0.2-96.6 events/h) were evaluated by mag

154 sue structures in 48 control subjects (apnea-hypopnea index, 2.0 +/- 1.6 events/hour) and 48 patients

155 e recruited 30 obese control subjects (apnea-hypopnea index, 4.7 +/- 3.1 events per hour) and 72 obes

156 [10] yr; median [interquartile range] apnea-hypopnea index, 41 [35-53]; mean [SD] Epworth sleepiness

157 Seventeen subjects (apnea-hypopnea index, 42.6 +/- 6.2 [SEM]) were studied during

158 nd 72 obese patients with sleep apnea (apnea-hypopnea index, 43.5 +/- 28.0 events per hour).

159 our) and 48 patients with sleep apnea (apnea-hypopnea index, 43.8 +/- 25.4 events/hour).

160 OSA prevalence was 65% (median apnea-hypopnea index, 7.2; range, 0-93), 40% of which were mod

161 isodes of apnea and hypopnea per hour (apnea-hypopnea index, AHI).

162 pneas and hypopneas per hour of sleep (apnea-hypopnea index, AHI).

163 Body mass index, apnea-hypopnea index, and cognitive abilities were modeled as

164 Cheyne-Stokes respiration, obstructive apnea-hypopnea index, and percentage of sleep time with less t

165 1765, GPR83, P = 1.90 x 10(-8) for the apnea-hypopnea index, and rs35424364; C6ORF183/CCDC162P, P = 4

166 uration as measured by pulse oximetry, apnea-hypopnea index, and the fraction of events that were hyp

167 The effects of severe apnea (apnea-hypopnea index, at least 30 episodes/h), which occurred

168 metaanalyzed for association with the apnea-hypopnea index, average oxygen saturation during sleep,

169 s assessed for baseline sleep indices: apnea-hypopnea index, central sleep apnea (central apnea index

170 Apnea hypopnea index, defined as number of apneas and hypopnea

171 to severe sleep-disordered breathing (apnea-hypopnea index, measured as events/hour, >/=15) are 10%

172 es focused on traits defined using the apnea-hypopnea index, which contains limited information on po

173 groups and correlated negatively with apnea-hypopnea index.

174 Nocturnal polysomnography to evaluate apnea-hypopnea index.

175 matched for age, body mass index, and apnea/hypopnea index.

176 overnight sleep study to determine an apnea-hypopnea index.

177 nt gradations of OSA severity based on apnea-hypopnea index.

178 ent in nocturnal oxygen saturation and apnea/hypopnea index.

179 leg fluid volume and either DeltaNC or apnea-hypopnea index.

180 uctive sleep apnea was assessed by the apnea-hypopnea index.

181 tion (SaO2); right putamen tCho/Cr and apnea hypopnea index; right putamen GABA/Cr and baseline SaO2;

182 re nocturnal oxygen saturation and the apnea/hypopnea index; secondary outcomes were sleep structure,

183 sleep apnea characterized by high apnea and hypopnea indices during rapid eye movement (REM) sleep.

184 Similar high apnea and hypopnea indices were also noted in prehypertensive spon

185 ent diagnostic sleep studies to obtain apnea-hypopnea indices.

186 During the hypopnea, laryngeal adductor activity was prominent, acc

187 Repeated episodes of apnea and hypopnea may result in desaturation and arousals, which

188 te ventilation initially increased, and then hypopnea occurred.

189 defined as an increased number of apneas and hypopneas on overnight monitoring.

190 d by periodic breathing that alternates with hypopnea or apnea.

191 Apnea occurred more than hypopnea (p < 0.0001).

192 01; 1.7 +/- 0.7 versus 4.1 +/- 0.5 mm Hg for hypopnea, p < 0.05).

193 more than 15 episodes per hour of apnea and hypopnea participated in the study.

194 eases in the number of episodes of apnea and hypopnea per hour (18 +/- 17, vs. 37 +/- 23 with placebo

195 rams showed 15 or more episodes of apnea and hypopnea per hour (apnea-hypopnea index, AHI).

196 onse and the number of episodes of apnea and hypopnea per hour during sleep (r=0.6, P=0.01).

197 a index (the number of episodes of apnea and hypopnea per hour of sleep).

198 ing, with more than 10 episodes of apnea and hypopnea per hour.

199 our (25.1 versus 17.1; P < 0.0001) and apnea-hypopneas per hour (27.2 versus 15.2; P < 0.0001) and gr

200 The frequency of apneas and hypopneas per hour of sleep (apnea-hypopnea index) was d

201 graphy to assess the frequency of apneas and hypopneas per hour of sleep (apnea-hypopnea index, AHI).

202 ratory disturbance indices (number of apneas/hypopneas per hour of sleep) corrected for normal increa

203 ea index (AHI; average number of apneas plus hypopneas per hour of sleep), systolic/diastolic hyperte

204 -disordered breathing (more than 5 apneas or hypopneas per hour of sleep).

205 (RDI), defined as the number of apneas plus hypopneas per hour of sleep, measured during in-home pol

206 (RDI), defined as the number of apneas plus hypopneas per hour of sleep, was measured during in-home

207 ndex (AHI, the average number of apneas plus hypopneas per hour of sleep, with apnea defined as a ces

208 opnea index, defined as number of apneas and hypopneas per hour of sleep.

209 index (AHI)-the average number of apneas and hypopneas per hour of sleep.

210 nea-hypopnea index (average number of apneas/hypopneas per hour) and the hypoxemia index (percentage

211 f 15 or more events (occurrences of apnea or hypopnea) per hour, and a predominance of central events

212 uctive airways disease (OAD) and sleep apnea-hypopnea (SAH) nor the sleep consequences of each disord

213 Obstructive sleep apnea hypopnea syndrome (OSAHS) is a prevalent disorder, for w

214 ice in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) who require higher CPAP (10 cm

215 tes in patients with obstructive sleep apnea hypopnea syndrome (OSAHS).

216 Around 50% of patients with the sleep apnea/hypopnea syndrome (SAHS) are not obese: body mass index

217 is increasing evidence that the sleep apnea-hypopnea syndrome (SAHS) is associated with daytime hype

218 as performed with 46 adults with sleep apnea-hypopnea syndrome (SAHS) to determine the effect of ther

219 ted for treatment of snoring and sleep apnea/hypopnea syndrome (SAHS), but often it does not effect a

220 ure (CPAP) are used to treat the sleep apnea/hypopnea syndrome (SAHS).

221 Patients with obstructive sleep apnea/hypopnea syndrome can experience residual daytime sleepi

222 ess in patients with obstructive sleep apnea/hypopnea syndrome who are regular users of nasal continu

223 ronic hypercapnia in obstructive sleep apnea/hypopnea syndrome.

224 O2)) during spontaneous breathing, the apnea-hypopnea threshold for CO2, and then calculated the diff

225 leep nor proportionally decrease their apnea-hypopnea threshold.

226 ons were among RDIs that required apneas and hypopneas to be associated with some level of desaturati

227 starting bronchoscopy when hypoventilation (hypopnea, two successive breaths of at least 50% reducti

228 defined by various definitions of apneas and hypopneas were assessed in 5,046 participants in the Sle

229 ET(CO2) thereby protecting against apnea and hypopnea, whereas reduced ventilatory drive and hypovent