ライフサイエンスコーパス: hypospadias

1 (cleft palate, cleft lip, anal atresia, and hypospadias).

2 anomalies, especially cryptorchidism and/or hypospadias.

3 re older (p = 0.048) compared with boys with hypospadias.

4 , all of which have been implicated in human hypospadias.

5 ght into possible genetic mechanisms causing hypospadias.

6 such as cryptorchidism, urethral defects and hypospadias.

7 e-scale analysis of phytoestrogen intake and hypospadias.

8 sures to estrogenic compounds impact risk of hypospadias.

9 lies cryptorchidism (undescended testis) and hypospadias.

10 cellent outcomes for distal but not proximal hypospadias.

11 yndrome disorders, namely cryptorchidism and hypospadias.

12 tween chlordane levels and cryptorchidism or hypospadias.

13 ion during the external genital phase causes hypospadias.

14 ween placental weight and cryptorchidism and hypospadias.

15 tract, including digit loss, syndactyly, and hypospadias.

16 wth factor receptor 2 (Fgfr2) exhibit severe hypospadias.

17 be the best approach for midshaft and distal hypospadias.

18 m a completely female appearance to isolated hypospadias.

19 hat included vaginal and uterine defects and hypospadias.

20 (1.9%), breast mass (1.2%), club foot (1%), hypospadias (0.6%), hydrocephalus (0.6%), cleft lip or p

21 eo-oesophageal anomalies (2.25 [0.96-5.26]), hypospadias (1.96 [0.98-3.92]), and gastroschisis (3.19

22 ), injuries or wounds (54.7% and 98.9%), and hypospadias (50% and 100%).

23 o compare AGD in boys with cryptorchidism or hypospadias against normative data.

24 The odds ratio for hypospadias (among all mothers) was 0.8 (95% CI: 0.7, 1.

25 ng follow-up, 1,713 boys were diagnosed with hypospadias and 6,878 with cryptorchidism (3,624 underwe

26 s loss of ectodermal Fgfr2 results in severe hypospadias and absence of the ventral prepuce.

27 ow window of prenatal development results in hypospadias and chordee, whereas earlier disruptions cau

28 g window did blocking androgen action induce hypospadias and cryptorchidism and altered penile length

29 al testis, causing TDS-consistent effects of hypospadias and cryptorchidism.

30 sduce develop with variably penetrant severe hypospadias and incomplete midline fusion of the primiti

31 types: endodermal Fgfr2 deletion causes mild hypospadias and inhibits maturation of a complex urethra

32 dation, microcephaly, digital abnormalities, hypospadias and loose connective tissue) and resemble on

33 s in select reproductive organs (e.g. penile hypospadias and prostate dysgenesis but normal testis),

34 Ventral penile curvature occurs in both hypospadias and so-called 'chordee without hypospadias',

35 developmental link between Hoxa13-associated hypospadias and those produced by antagonists to androge

36 h hypospadias and so-called 'chordee without hypospadias', and so its correction is a topic of releva

37 Incomplete urethral tubularization (hypospadias) and anorectal abnormalities are two common

38 crypt-orchidism, 1.2 (95% CI: 0.6, 2.4) for hypospadias, and 1.9 (95% CI: 0.9, 4.0) for polythelia.

39 217 sons with cryptorchidism, 197 sons with hypospadias, and 557 sons with neither condition.

40 7,20-lyase deficiency, including micropenis, hypospadias, and gynecomastia, who is homozygous for CYP

41 irth, the 46,XY proband had a bifid scrotum, hypospadias, and micropenis consistent with clinical sta

42 ispose to the development of cryptorchidism, hypospadias, and WTs.

43 he male genital anomalies cryptorchidism and hypospadias are prematurity and low birth weight.

44 ale urogenital anomalies--cryptorchidism and hypospadias--are poorly understood.

45 sm were longer than mean values in boys with hypospadias (both p < 0.01) and shorter than mean values

46 al defect characterized by hypertelorism and hypospadias, but additional midline malformations are al

47 developmental factors in the development of hypospadias, but there is doubt whether the incidence of

48 e analysis included data on mothers of 1,250 hypospadias cases and 3,118 controls who delivered their

49 association study on 1,006 surgery-confirmed hypospadias cases and 5,486 controls from Denmark.

50 thers of 593 gastroschisis cases, 1,142 male hypospadias cases, and 4,399 nonmalformed controls.

51 Reports of CPAs, which include hypospadias, chordee, micropenis, and ambiguous genitali

52 ed with many common birth defects, including hypospadias, cleft lip with or without cleft palate, or

53 twins and by patterns of cryptorchidism and hypospadias co-occurrence in individuals.

54 reproductive tract abnormalities (including hypospadias, cryptorchidism, hypospermatogenesis, and te

55 en external urogenital and anorectal tracts; hypospadias - ectopic ventral positioning of the urethra

56 of a small utricle (not in the patient with hypospadias), ejaculatory duct reflux, internal urachal

57 rgical techniques for treating patients with hypospadias, exstrophy, incontinence, and ambiguous or v

58 Boys with hypospadias had shorter mean AGD and penile length SDS t

59 iation between placental weight at birth and hypospadias has been indicated.

60 52, 95% confidence interval: 1.31, 1.76) and hypospadias (hazard ratio = 1.97, 95% confidence interva

61 deletion of Fgfr2 results in the most severe hypospadias highlights a major role for Fgfr2 in the dev

62 mass, obstetric fistula, undescended testes, hypospadias, hydrocephalus, cleft lip or palate, and clu

63 ses, obstetric fistulas, undescended testes, hypospadias, hydrocephalus, cleft lip/palate, and clubfo

64 We examined whether risk of hypospadias (i.e., a congenital malformation in which th

65 beta-catenin knockout animals develop severe hypospadias in both sexes raises the possibility that th

66 ental and molecular mechanisms that underlie hypospadias in Fkbp52-deficient mice.

67 Fgfr2 or its ligand Fgf10 results in severe hypospadias in mice, in which the entire urethral plate

68 nor abnormalities at or shortly after birth (hypospadias in one baby and rotation of small intestine

69 nile length SDS decreased as the severity of hypospadias increased (ptrend = 0.078).

70 patient presented with developmental delay, hypospadias, inguinal hernia and dysmorphic features whi

71 cele [adult and paediatric]), hydrocephalus, hypospadias, injuries or wounds, neck mass, undescended

72 Hypospadias is a common birth defect in humans, yet its

73 Hypospadias is a common congenital condition in boys in

74 Hypospadias is a congenital defect of the external genit

75 Hypospadias is a urethral tube defect defined by misloca

76 but there is doubt whether the incidence of hypospadias is increasing or not.

77 of FK506-binding protein-52 (Fkbp52) develop hypospadias, most likely due to actions of Fkbp52 as a m

78 d adjusted odds of cryptorchidism (n = 219), hypospadias (n = 199), and polythelia (extra nipples) (n

79 chidism (n = 71, age 13.4 +/- 5.8 months) or hypospadias (n = 81, age 11.4 +/- 6.2 months) were recru

80 In Hoxa13(GFP)-mutant mice, hypospadias occur as a result of the combined loss of Fg

81 Other abnormalities included hypospadias, opacification of a small utricle (not in th

82 and penile length were reduced in boys with hypospadias or cryptorchidism relative to normative data

83 rders of fetal masculinization, resulting in hypospadias or cryptorchidism, are common, but their cau

84 ychlordane level in either cryptorchidism or hypospadias (p-trend all > 0.45).

85 Severe hypospadias, particularly that associated with significa

86 expression in the urethra, and an associated hypospadias phenotype, suggesting that these genes are d

87 The use of engineered tissue substitutes in hypospadias reconstruction has also been applied clinica

88 as challenged more traditional approaches to hypospadias repair and is now considered by many pediatr

89 Many technical aspects of hypospadias repair and variations of perioperative manag

90 of penile degloving procedures, phimosis or hypospadias repair, and penile cancer resection.

91 After more than 100 years of innovation in hypospadias repair, new concepts regarding penile curvat

92 otentially be preserved in both phimosis and hypospadias repair.

93 quartile-specific ORs for cryptorchidism or hypospadias show no notable associations with trans-nona

94 Hypospadias surgery has been in continuous evolution for

95 Continuing innovation in hypospadias surgery offers additional options for straig

96 Further development of hypospadias surgery would benefit from objective, standa

97 le to simplify decision-making algorithms in hypospadias surgery, while achieving good functional and

98 The relationship seemed stronger for hypospadias than for cryptorchidism.

99 exhibit genital anomalies, which range from hypospadias to complete male-to-female sex reversal.

100 cial support with risks of gastroschisis and hypospadias, using data from the National Birth Defects

101 in the bladder wall; affected males may have hypospadias (ventrally misplaced urethral opening) of va

102 ongenital heart defects, inguinal hernia, or hypospadias were also reported.

103 Cryptorchidism and hypospadias were associated with low weight-for-gestatio

104 AGD in human infants with cryptorchidism and hypospadias, which are potential manifestations of TDS d

105 surgical techniques have been developed for hypospadias, with excellent outcomes for distal but not