ライフサイエンスコーパス: hypotheses

1 , but by ecologically relevant questions and hypotheses.

2 pulation include the osmotic and the thermal hypotheses.

3 lysis offers a new opportunity to test these hypotheses.

4 tive modelling to test the validity of these hypotheses.

5 th unbiased approaches and tests of a priori hypotheses.

6 ure patients under both null and alternative hypotheses.

7 re the importance of the forage and movement hypotheses.

8 We interpreted our results considering two hypotheses.

9 ed a murine oral implant model to test these hypotheses.

10 fferent biological contexts and generate new hypotheses.

11 ession analyses were performed to test study hypotheses.

12 necessarily mutually exclusive from current hypotheses.

13 n, escaped genes, and primordial virus world hypotheses.

14 to generate data-driven mechanism-of-action hypotheses.

15 d a set of unexpected rules to help generate hypotheses.

16 ons that directly and easily tested specific hypotheses.

17 population control for many population-level hypotheses.

18 ies and the evaluation of multiple competing hypotheses.

19 estigations with which to test their various hypotheses.

20 al activation experiments that support these hypotheses.

21 The current investigation tested these hypotheses.

22 ibody testing and generate disease mechanism hypotheses.

23 r models, and limited derivation of testable hypotheses.

24 We tested 2 hypotheses: (1) among DSBCS patients, second-eye outcome

25 s from human subjects are being used to test hypotheses about abnormal neural computations in autism,

26 One approach to generate new hypotheses about aging is to use unbiased methods to loo

27 descriptive tool and can be used to develop hypotheses about cellular organization and dynamics.

28 manities working together to rigorously test hypotheses about general rules that may have shaped huma

29 Immune correlate studies are providing novel hypotheses about immunological mechanisms that may be re

30 oupling, allowing the generation of testable hypotheses about its past, present, and future dynamics

31 decades of ages provides a means to generate hypotheses about lifespan trajectories in brain phenotyp

32 th state, and, such patterns may help refine hypotheses about modes of pathogenesis.

33 o vertebrates will be invaluable for testing hypotheses about notochord evolution.

34 ted by insufficient information to formulate hypotheses about population sensitivity to high temperat

35 and links these taxa and individual OTUs to hypotheses about processes governing biogeochemical cycl

36 ons to transcriptional variation and to test hypotheses about regulatory evolution.

37 ed States) participants in order to generate hypotheses about social and environmental factors relate

38 ial learning across adolescence and generate hypotheses about social dysfunctions in psychiatric popu

39 Because we had prior hypotheses about the caudate, we performed a confirmator

40 t, representational models can be defined as hypotheses about the distribution of activity profiles a

41 ular mechanisms allows for the generation of hypotheses about the evolution of neural anatomy and fun

42 The VWFA is a critical region for testing hypotheses about the nature of cortical organization, be

43 ous nature of the recordings to test several hypotheses about the population-based mechanisms driving

44 way to simultaneously test multiple specific hypotheses about the representations of speech without u

45 s, providing quantitative data in support of hypotheses about the use of unusual formal features and

46 the entities involved are conducted to test hypotheses about these networks.

47 approaches, and also generates more accurate hypotheses about tissue-specific protein actions.

48 tic regression approach for testing a priori hypotheses about variation in the odds of transmission g

49 d considerable weight to three long-standing hypotheses according to which the sex disparity of ASD i

50 pproach has therefore generated new testable hypotheses and alternative interpretations of experiment

51 ion model to assess the strength of existing hypotheses and data that account for these disparities.

52 oring high dimensional data sets to generate hypotheses and discovering novel insights.

53 a" has been sold as a panacea for generating hypotheses and driving new frontiers of health care; the

54 aph encoding to preserve multiple structural hypotheses and exploit recent advances in representation

55 a key assumption in many existing ecological hypotheses and has been declared a general macroecologic

56 hypotheses, there remains a need for testing hypotheses and interpreting results with scientific rigo

57 -Boston, Chicago, and Los Angeles-to develop hypotheses and methodological strategies for assessing h

58 Current hypotheses and models of food allergy do not adequately

59 Future work should test pathophysiological hypotheses and novel interventions targeting reward- and

60 mulations allow researchers to pose and test hypotheses and perform experiments in silico.

61 functional studies confirmed the model-based hypotheses and provided evidence for protein misfolding

62 Due to the testing of a large number of hypotheses and relatively small sample sizes, results fr

63 e proxies already in use, we can develop new hypotheses and specify criteria for new and needed proxi

64 e results from Cedar Creek (MN) support both hypotheses and suggest that sensitivity to drivers varie

65 alytical: researchers study embryos, suggest hypotheses and test them through experimental perturbati

66 e amyloid cascade (ACH) and presenilin (PSH) hypotheses and the amyloid precursor protein (APP) matri

67 ogenetic comparative framework to test these hypotheses, and considered forearm length as both a prox

68 Alternate hypotheses are also discussed.

69 Some emerging hypotheses are an imbalance between indirect and direct

70 Two competing hypotheses are currently debated.

71 ocess in which a model is learned from data, hypotheses are generated from the model to propose infor

72 es, common records used to investigate these hypotheses are incomplete or unavailable, biasing existi

73 We show here that such hypotheses are insufficient to account for the observed

74 The models encoding these hypotheses are predicated on mutually antagonistic Rac-R

75 of OMICS has provided more depth to existing hypotheses as well as new insights in the etiology of de

76 ce, and is central to current origin of life hypotheses as well as the search for microbial life on t

77 Here we quantitatively test these three hypotheses at a large geographic scale and across 20 spe

78 needed to evaluate numerous paleobiological hypotheses at and prior to the root of our lineage.

79 global change, is ideally suited for testing hypotheses at broad geographic, taxonomic, and temporal

80 By testing two group-level hypotheses based on benefit-cost analysis and social str

81 ults are inconsistent with simple constraint hypotheses because the rate of evolution is very low rel

82 mental predictability and climatic stability hypotheses, but productivity and topographic complexity

83 Observational studies can generate hypotheses by evaluating novel exposures or biomarkers a

84 We tested the PEP-limitation hypotheses by feeding leaves with the PEP carboxylase co

85 Here, we test these competing hypotheses by having male and female humans detect natur

86 to environmental change while developing new hypotheses concerning adaptation to urban infrastructure

87 nalyses in children and allow examination of hypotheses concerning endocrine effects from dietary com

88 Many of the hypotheses concerning how and why hybridization contribu

89 Many hypotheses concerning the nature of early life assume th

90 ork, we statistically evaluated evolutionary hypotheses concerning the origin of a recently recognize

91 emonstrate how our model can be used to test hypotheses concerning the roles of different hotspot and

92 Consistent with these hypotheses, crowding out was driven by those who donated

93 This discrepancy has fostered two hypotheses: either other aspects of V1 continue changing

94 ifferent methods are being used to test such hypotheses: encoding analysis, pattern component modelin

95 d by the GEOCARBSULFvolc model support these hypotheses, excluding the volcanism-driven oceanic anoxi

96 Several hypotheses explain this extensive radiation [3], one of

97 listic range of prior probabilities for null hypotheses, false report probability is likely to exceed

98 associated with four not mutually exclusive hypotheses: food-perishability, consumption-time, resour

99 To evaluate alternative hypotheses for associations between first-trimester anti

100 essential to considering various mechanistic hypotheses for biological (and synthetic) nitrogen fixat

101 leverage molecular data sets to develop new hypotheses for disease mechanisms, identify new disease

102 egulatory changes suggest strong mechanistic hypotheses for disease risk, but we conclude that most r

103 drial complex I activity is one of the major hypotheses for dopaminergic neuron death in Parkinson's

104 These interaction motifs provide hypotheses for fungal-driven dynamics behind observed pl

105 ecular changes at the tissue level, building hypotheses for further investigation in DN and providing

106 fication of flowers, leading to new testable hypotheses for future research on angiosperms.

107 We generate several hypotheses for future research.

108 Preplanned subgroup analyses provide hypotheses for future studies.

109 community context and then present a set of hypotheses for future work.

110 cal model-based computational screen to test hypotheses for gradient formation.

111 We tested several hypotheses for how geographic and climatic variables sho

112 vations as constraints to test a sequence of hypotheses for how intracellular (GTPase) and ECM signal

113 this study, we evaluated multiple competing hypotheses for how metabolism of these parent estrogens

114 We then tested hypotheses for how these traits should vary as a functio

115 eaf and canopy characteristics to test three hypotheses for satellite-observed canopy reflectance sea

116 ignificance level and can be adapted to test hypotheses for specific phases of the gait cycle.

117 over effects and their mechanisms by uniting hypotheses for the causes and consequences of habitat se

118 o reducing with respect to the most accepted hypotheses for the conditions on primordial Earth.

119 Combined, these findings provide new hypotheses for the genomic origins, biological conservat

120 In this review, we will discuss the various hypotheses for the mechanism of SIT and we will put forw

121 Hypotheses for the muscular basis of this performance di

122 We discuss two hypotheses for the origin of animal cell types: division

123 ins the appeal of morphology-based polyphyly hypotheses for the origins of Lissamphibia while reconci

124 We also tested alternative hypotheses for the phylogenetic positions of ants and be

125 species, in particular, have led to several hypotheses for the processes underlying the molecular ev

126 t are largely consistent with other proposed hypotheses for the renewed growth of atmospheric methane

127 d to form similar structures, suggesting new hypotheses for their functions and evolutionary historie

128 counterparts and to discuss the mechanistic hypotheses for those reactions that are currently active

129 ling in thermogenesis together with testable hypotheses for understanding mechanisms and developing t

130 cuss the implications of the two alternative hypotheses for understanding the origin of animals.

131 We propose two alternative hypotheses for why a system decreases the distance from

132 We investigated several hypotheses for why the phenotype may be absent, with the

133 trasting empirical data and provide testable hypotheses for yet unexplored patterns.

134 s to the extraction of insights and testable hypotheses from big, sometimes noisy data.

135 emains to be elucidated to inform functional hypotheses further is whether a pattern exists in the st

136 Two hypotheses, gaze aversion and gaze indifference, are com

137 ical analyses that tested key aspects of the hypotheses generated by the molecular dynamics simulatio

138 based and machine learning methodologies for hypotheses generation in gap filling and metabolic model

139 NM] and geometric morphometrics) to test two hypotheses: given their behavioral, morphological, and e

140 we show here that it can be used to develop hypotheses guiding biochemical experiments for establish

141 Simple lag hypotheses have become prominent in disequilibrium ecolo

142 oms, but over time the basic tenets of these hypotheses have become unclear.

143 Although a variety of hypotheses have been presented as to the biphasic nature

144 Two hypotheses have been proposed to explain MHC specificity

145 Several hypotheses have been proposed to explain these differenc

146 Two competing hypotheses have been proposed to explain this diel starc

147 Several hypotheses have been proposed to explain this genomic va

148 Competing hypotheses have been proposed: the direction of flow is

149 Two main hypotheses have been proposed: the paranotal hypothesis,

150 However, none of the hypotheses have been tested in vivo.

151 A variety of contrasting hypotheses have emerged in the literature to explain phy

152 ion modulates visual information codes, such hypotheses have largely relied on the extrapolation of s

153 Although several hypotheses have provided insights into the interaction,

154 te severe traumatic brain injury to test two hypotheses: (i) in patients who lack behavioural evidenc

155 esses within species and are consistent with hypotheses implicating age and environmental stability i

156 s and offers an attractive technique to test hypotheses implicating telomere length in various cardia

157 hibitory processes, the authors tested these hypotheses in adults followed since childhood, contrasti

158 explore these datasets and generate testable hypotheses in an effective and intuitive manner.

159 athways to help scientists generate testable hypotheses in an effort to understand the etiology and m

160 cial systems that would allow us to test the hypotheses in detail are still lacking.

161 ween these two disorders will engender novel hypotheses in future preclinical and clinical studies.

162 Researchers can then test these hypotheses in RCTs.

163 help to lay the foundation for entirely new hypotheses in the field.

164 Most hypotheses in the heated debate about the Neanderthals'

165 The authors evaluated both mechanistic hypotheses in two sets of experiments at the time of ini

166 not always possible to rigorously test these hypotheses in vivo We applied in vitro biophysical and b

167 w that the resulting clusters lead to useful hypotheses: in the case of genetic regulation these conc

168 Hypotheses include inequity aversion, a moral sense that

169 matically described here can clarify various hypotheses including those of large-polaron charge trans

170 ws for statistical tests of several relevant hypotheses, including a range shift test, a stopover tes

171 comprehensive assessment of these competing hypotheses, including estimates of uncertainty.

172 In partial support of these hypotheses, increasing SR or FGR (holding the other cons

173 Here, we call both hypotheses into question.

174 Collectively, our data support hypotheses invoking nutrient limitation as a central dri

175 d neurodegeneration by testing two competing hypotheses involving frontal regions' activity (neurodeg

176 However, support for these hypotheses is scarce.

177 aging, but a major impediment to testing ASD hypotheses is the lack of human cell models.

178 Moreover, since validation of hypotheses made by gap filling tools require experimenta

179 Africa, Europe, and Asia to test alternative hypotheses of body mass evolution.

180 n cardiovascular imaging, including clinical hypotheses of improving patient outcomes, the importance

181 We use a microsatellite data set to test hypotheses of population connectivity and refugial isola

182 Based on these maps, we generated hypotheses of regions of the brain causally related to s

183 te that the most investigated candidate gene hypotheses of schizophrenia are not well supported by ge

184 nd may unify a number of currently competing hypotheses of SCZ pathophysiology.

185 We review hypotheses of the cell of origin of liver tumorigenesis

186 we are able to generate testable mechanistic hypotheses of the molecular changes that drive disease r

187 e cancer research community by providing new hypotheses on compound MoA and potential insights for dr

188 nd tolerated variants that can also generate hypotheses on specific molecular events disrupted by the

189 ains involved in the interaction, suggesting hypotheses on the causal link between diseases.

190 ssed) meat digestion, supporting the current hypotheses on the causal link between red and processed

191 sistency by verifying some commonly accepted hypotheses on the evolution of these disharmonies by mea

192 role in structuring communities, and propose hypotheses on the factors that shape bacterial biogeogra

193 Our data challenge current published hypotheses on the influence of genetic variation on this

194 In malaria pathophysiology, divergent hypotheses on the inhibition of hematin crystallization

195 We contrast two hypotheses on the relationship between green and brown f

196 These venerable hypotheses persist in models of aesthetic processing [3-

197 Four trait-scaling hypotheses (plant functional type, nutrient limitation,

198 Simple evolutionary hypotheses predict such a relationship if the supply of

199 namics and the ability to examine ecological hypotheses previously untestable outside of theoretical

200 All hypotheses produced global GPP that was highly correlate

201 Multiple hypotheses propose an ostensibly disparate array of driv

202 Two hypotheses propose to explain this negative relationship

203 dopamine in schizophrenia and the prominent hypotheses put forth regarding alterations in dopaminerg

204 While there have been several hypotheses put forward to explain the enormous success o

205 We linked hypotheses regarding different types of factors and info

206 s it difficult to develop testable molecular hypotheses regarding host-microbe interactions.

207 Our mapping analysis allowed us to build hypotheses regarding HOXA5 functions in the nervous syst

208 computations in autism, with an emphasis on hypotheses regarding potential excitation/inhibition imb

209 ies of recent studies which have sparked new hypotheses regarding the function of claustral circuits.

210 emonstrate how this tool has generated novel hypotheses regarding the mechanisms by which Th17-cell p

211 ctured, state-space models to test different hypotheses regarding the spatial structure of a populati

212 We studied one of the hypotheses regarding this size-selective removal: the fo

213 Few studies in AD have tested hypotheses regarding which medication will work best for

214 otential to be powerful tools for generating hypotheses related to gene-environment interplay in huma

215 nd 42 states in the conterminous USA to test hypotheses relating abnormalities and four categories of

216 es of this increase remain unclear; proposed hypotheses rely on fluctuations in either the magnitude

217 ts from such screens and generating testable hypotheses requires training in bioinformatics and the s

218 are generally based on plausible biological hypotheses, some are found to not correlate well with cl

219 Finally, we found no support for alternative hypotheses such as a female preference for aggressive ma

220 A number of domestication hypotheses suggest that dogs have acquired a more tolera

221 Current hypotheses suggest that reactivation contributes to memo

222 These hypotheses suggest that the most suitable/attractive hos

223 s across societies and can also be linked to hypotheses suggested by earlier empirical studies in soc

224 Contrary to previous hypotheses suggested by the patrilocality of many agricu

225 arious regions of the cerebral cortex and by hypotheses surrounding its possible role in multimodal s

226 Bonferroni corrected for the multiplicity of hypotheses tested (n = 8).

227 ain the lack of statistical evidence for the hypotheses tested.

228 ignificant after correction for the multiple hypotheses tested.

229 ucture to perform in silico, high-throughput hypotheses testing on such predicted methylation or hydr

230 To test the hypotheses that (1) antemortem cerebrospinal fluid (CSF)

231 ABSTRACT: We examined the hypotheses that (1) at rest, endothelial function would

232 Here, we tested the hypotheses that (1) pLTF expression in young, gonadally

233 g studies of normal subjects and support the hypotheses that (i) cerebellar efferents target frontal

234 Our findings do not support the hypotheses that a greater consumption of high-fat dairy

235 zophrenia, and as a consequence generate new hypotheses that are testable in patients.

236 To test the hypotheses that birds select supportive winds and that s

237 nal data and providing competing mechanistic hypotheses that can be experimentally tested.

238 ffect group level outcomes, and suggests new hypotheses that can be explored empirically.

239 We sought to test the hypotheses that claudin-18 is a determinant of airway ep

240 nsible for scientific misconduct, supporting hypotheses that connect bias to situational factors, lac

241 ble intramolecular H-bond, while alternative hypotheses that could explain the higher relaxivity were

242 We show that several hypotheses that depend on the evaporating sites require

243 Our results support the hypotheses that dysregulation of neuronal-activity-depen

244 To test the hypotheses that estradiol and time of day signals alter

245 t that more research should focus on testing hypotheses that explain spider silk property variations

246 difficult to reconcile with many alternative hypotheses that have been proposed for the origin of ove

247 Testing hypotheses that implicate changing atmospheric CO2 level

248 These impairment experiments support hypotheses that magnetic field perception in sharks is n

249 These data are consistent with the hypotheses that Nogo receptors are membrane-bound growth

250 g the geography of omnivory, we tested three hypotheses that predict the proportion of animal tissue

251 m and ecology of early cells and for testing hypotheses that propose that the eukaryotic nuclear line

252 We tested the hypotheses that reperfusion therapy with tenecteplase wo

253 C-less plants experimentally support classic hypotheses that SCs permit greater stomatal responsivene

254 These findings support our hypotheses that statin use is inversely associated, and

255 Results call those domestication hypotheses that suggest dogs evolved greater cooperative

256 This study examines the hypotheses that the IgG3-H435 variant promotes increased

257 We tested the hypotheses that the measured traits would be significant

258 tal growth, and the present study tested the hypotheses that thyroid hormones promote beta cell proli

259 gnetic resonance spectroscopy, we tested the hypotheses that, at the same power: ATP synthesis rates

260 In this study, we tested the hypotheses that, in a very large scale GWAS, we would id

261 There are two prevailing hypotheses: that it is a physicochemically dominated pro

262 Counter to the reverse epidemiology hypotheses, the protective effects of obesity were less

263 o address five of the current oxygen sensing hypotheses: the lactate-Olfr 78 hypothesis of oxygen che

264 ing unexpected structure in data to generate hypotheses, there remains a need for testing hypotheses

265 etrieve and combine data sets and to develop hypotheses through data exploration.

266 We tested our hypotheses through univariate and bivariate heritability

267 lement filters to remove data sets where the hypotheses to be tested cannot achieve significance.

268 delling to compare competing trophic cascade hypotheses to explain how dingoes could influence shrub

269 gging strand templates, and propose testable hypotheses to gain further insights.

270 upon previous findings and set the stage for hypotheses to guide future modeling and experimental ana

271 r direct conversion, and to suggest specific hypotheses to improve cell fate engineering protocols.

272 nitrogen limitation and habitat productivity hypotheses use the same logic to predict more animal con

273 ly plausible support for the self-medication hypotheses used to explain high rates of cannabis use in

274 Here we systematically test these hypotheses using a microfluidics assay to mechanically w

275 y experiments to test circuit and behavioral hypotheses using a variety of manipulations, including g

276 n = 41 and 39 participants), we tested these hypotheses using functional neuroimaging.

277 to patients under both null and alternative hypotheses using NCI and Alliance data, and then computi

278 To test these various hypotheses we performed a logistic meta-regression analy

279 To disentangle these hypotheses, we asked two questions: are legumes hardwire

280 To test these hypotheses, we assessed two therapies in Tk2(-/-) mice:

281 To test these hypotheses, we compared interneuronal progenitors in the

282 To test between competing hypotheses, we constructed a massive repository of histo

283 Consistent with these hypotheses, we found that activated mouse and human T ce

284 Consistent with these hypotheses, we found that high N availability increased

285 Consistent with our hypotheses, we found that: (1) perturbations increased E

286 To evaluate these hypotheses, we investigated associations between cerebro

287 To test the two competing hypotheses, we measured (87)Sr/(86)Sr and delta(13)C of

288 e method's efficacy in generating biological hypotheses, we performed WGBS of primary macrophages der

289 To test these hypotheses, we studied contractile force, mitochondrial

290 The primary and secondary hypotheses were noninferiority (margin: 5 letters at a 1

291 te and multivariate analyses of the a priori hypotheses were performed and reported with correlation

292 The research hypotheses were tested in three subsamples with differen

293 Hypotheses were tested using cultured myoblasts and fibr

294 Key hypotheses were that (1) the tax would be passed through

295 The coprimary hypotheses were that exenatide, administered once weekly

296 Our a priori hypotheses were that underreporting by the NVSS would ex

297 rial used a 2x2 factorial design to test two hypotheses: whether use of accelerated epirubicin would

298 This work stands in contrast to classical hypotheses, which predict a positive effect of productiv

299 nitrogen limitation and habitat productivity hypotheses, which predict more animal consumption in N-p

300 ne both the multiple-demand and sensory-bias hypotheses within caudal portions of human LFC (both men